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Journal of Obstetrics and Gynaecology Volume 22, 2002 - Issue 4
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Original Article

Maternal homocysteine levels and plasma lipids in gestational diabetes: is there any relationship?

N. Vitoratos Second Department of Obstetrics and Gynecology, University of Athens, Areteion Hospital, Athens
,
D. Kassanos Second Department of Obstetrics and Gynecology, University of Athens, Areteion Hospital, Athens
,
E. Salamalekis Second Department of Obstetrics and Gynecology, University of Athens, Areteion Hospital, Athens
,
Ch. Sirisratidis Second Department of Obstetrics and Gynecology, University of Athens, Areteion Hospital, Athens
,
E. Baimacou Second Department of Obstetrics and Gynecology, University of Athens, Areteion Hospital, Athens
&
G. Creatsas Second Department of Obstetrics and Gynecology, University of Athens, Areteion Hospital, Athens
Pages 366-369 | Received 10 Sep 2002, Accepted 10 Sep 2002, Published online: 10 Sep 2002

  • Kapkan J.C., Labal S., England B.C., Zawacki C.M. and Herman W.H. (1999) Is pregnancy in diabetic women associated with folate deficiency. Diabetes Care, 22, 1017-1021.
  • Hyanek H., Stribrny J., Sebestra P., Niederle P., Kramar J., Kozich V, Orental O., Zaykova K., Mandysova E., Boruvka, V,et al. (1997) Hyperhomocysteinemia: a risk factor for the development of vascular diseases not associated with lipid levels. Casopis Lekaru Ceskych, 136, 720-723.
  • Mazza A., Motti C., NulIi A., Marra G., Gnasso A., Pastore A., Federici G. and Cortese C. (2000) Lack of association between carotid intima-media thickness and methylenetetrahydrofolat reductase gene polymorphism or aerum homocysteine in non-insulin-dependent diabetes mellitus. Metabolism, 49, 718-723.
  • Pavia C., Ferrer I., Valls C., Artuch R., Colome C. and Vilaseca M.A. Total homocysteine in patients with type I diabetes. Diabetes Care, 23, 84-87.
  • Pixa A., Pietzsch J., Julius U., Manschilowski M. and Hanefeld M. (2000) Impaired glucose tolerance (IGT) is not associated with disturbed homocysteine metabolism. Amino Acids, 18, 289-298.
  • Ray J.C. and Laskin C.A. (1999) Folic acid and homocysteine metabolism defects and the risk of placenta! abruption, preeclampsia and spontaneous pregnancy loss: a systematic review. Placenta, 20, 519-529.
  • Schleich M.P., John S., Jacobi J., lacker K.J. and Schmieder R.E. (2000) Mildly elevated homocysteine concentrations impair endothelium vasodilation in hypercholesterolemic patients. Atherosclerosis, 153, 386-389.
  • Powers R.W., Evans R.W., Majors A.K., Ojimba J.I., Ness R.B., Crombleholme W.R. and Roberts J.M. (1998) Plasma Homocysteine concentration is increased in pre-eclampsia and is associated with evidence of endothelial activation. American Journal of Obstetrics and Gynecology, 179, 1605-1611.
  • Steinberg H.O., Bayazeed B., Hook G., Jonson A., Cronic J. and Baron A.D. (1997) Endothelial dysfunction is associated with cholesterol levels in the high normal range in humans. Circulation, 96, 3286-3293.
  • Walker M.C., Smith G.N., Perkins S.L., Keely E.Z. and Garner RR. (1999) Changes in homocysteine levels during normal pregnancy. American Journal of Obstetrics and Gynecology, 180, 660-664.
  • Hollingsworth D.R. and Grundy S. (1982) Pregnancy associated hypertriglyceridemia in normal and diabetic women: differences in insulin-dependent, non-insulin dependent and gestational diabetes. Diabetes, 31, 1092-1097.
  • Vollset S.E., Refsum H., Irgens N.M., Emdlen B.M., Tverdal A., Gjessing H.K., Monsen A.L. and Veland P.M. (2000) Plasma total homocysteine, pregnancy outcomes. The Hordaland Homocysteine Study. American Journal of Clinical Nutrition, 71, 962-968.
  • Werstuck G.H., Leute S.R., Daval S., Hossain G.S., Sood S.K., Shi Y.Y., Zhou-Maeda N., Krisans S.K., Maninow--Moceda N., Kirsans S.K., Malinow M.R. and Austin R.C. (2001) Homocysteine--induced endoplasmic reticulum stress causes dysregulation of the cholesterol and trigyceride biosynthetic pathways. Journal of Clinical Investigation, 107, 1221-1222.
  • Aubard Y., Darodes N. and Cantaloube M. (2000) Hyperhocysteinemia and pregnancy--review of our present understanding and therapeutic implications. European Journal of Obstetrics, Gynecology and Reproductive Biology, 93, 157-165.
  • Carpenter N.W. and Coustan D.r. (1982) Criteria for screening tests for gestational diabetes. American Journal of Obstetrics and Gynecology, 144, 768-773.
  • de long S.C., van den Berg M., Rauwerda J.A. and Stehouwer C.D. (1998) Hyperhomocysteinemia and atherothtombotic disease. Seminars in Thrombosis and Hemostasis, 24, 381-385.
  • Gallistl S., Sudi K., Mangge H., Erwa W. and Borkenstein M. (2000) Insulin is an independent correlate of plasma homocysteine levels in obese children and adolescents. Diabetes Care, 23, 1348-1352.
  • Holven K.B., Holm T., Aukrust P., Christensen B., Kjekshus J., Andreassen A.K., GuIlestad L., Hagve T.A., Svilaas A., Ose L. and Nenseter M.S. (2001) Effects of folic treatment on endothelium--dependent vasodilation and nitric oxide-derived end products in hyperhomocysteinemic subjects. American Journal of Medicine, 110, 536-542.

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