219
Views
3
CrossRef citations to date
0
Altmetric
Reviews

Animal models in intrauterine adhesion research

ORCID Icon, , , ORCID Icon, & ORCID Icon

References

  • AAGL Advancing Minimally Invasive Gynecology Worldwide. 2010. AAGL practice report: practice guidelines for management of intrauterine synechiae. Journal of Minimally Invasive Gynecology 17:1–7.
  • Azizi R, Aghebati-Maleki L, Nouri M, Marofi F, Negargar S, Yousefi M. 2018. Stem cell therapy in Asherman syndrome and thin endometrium: stem cell- based therapy. Biomedicine & Pharmacotherapy = Biomedecine & pharmacotherapie 102:333–343.
  • Bazoobandi S, Tanideh N, Rahmanifar F, Tamadon A, Keshtkar M, Mehrabani D, et al. 2016. Induction of Asherman’s syndrome in rabbit. Journal of Reproduction & Infertility 17:10–16.
  • Cai H, Li H, He Y. 2016. Interceed and estrogen reduce uterine adhesions and fibrosis and improve endometrial receptivity in a rabbit model of intrauterine adhesions. Reproductive Sciences 23:1208–1216.
  • Cao J, Liu D, Zhao S, Yuan L, Huang Y, Ma J, et al. 2020. Estrogen attenuates TGF-β1-induced EMT in intrauterine adhesion by activating Wnt/β-catenin signaling pathway. Brazilian Journal of Medical and Biological Research = Revista brasileira de pesquisas medicas e biologicas 53:e9794.
  • Chai D, Cuneo S, Falconer H, Mwenda JM, D'Hooghe T. 2007. Olive baboon (Papio anubis anubis) as a model for intrauterine research. Journal of Medical Primatology 36:365–369.
  • Chen JX, Yi XJ, Gu PL, Gao SX. 2019. The role of KDR in intrauterine adhesions may involve the TGF-β1/Smads signaling pathway. Brazilian Journal of Medical and Biological Research = Revista brasileira de pesquisas medicas e biologicas 52:e8324.
  • Ding J, Zhang J, Li J, Li D, Xiao C, Xiao H, et al. 2019. Electrospun polymer biomaterials. Progress in Polymer Science 90:1–34.
  • Ebrahim N, Mostafa O, El Dosoky RE, Ahmed IA, Saad AS, Mostafa A, et al. 2018. Human mesenchymal stem cell-derived extracellular vesicles/estrogen combined therapy safely ameliorates experimentally induced intrauterine adhesions in a female rat model. Stem Cell Research & Therapy 9:175.
  • Fang Z-A, He Y, Sun C, Zhan L, Zhou G, Wei B, et al. 2021. Expression and potential role of CXCL5 in the pathogenesis of intrauterine adhesions. The Journal of International Medical Research 49:300060521997718.
  • Feng Q, Gao B, Zhao X, Huang H, Yi S, Zou L, et al. 2020. Establishment of an animal model of intrauterine adhesions after surgical abortion and curettage in pregnant rats. Annals of Translational Medicine 8:56.
  • Feng X, Li J, Zhang X, Liu T, Ding J, Chen X. 2019. Electrospun polymer micro/nanofibers as pharmaceutical repositories for healthcare. Journal of Controlled Release : Official Journal of the Controlled Release Society 302:19–41.
  • Healy MW, Schexnayder B, Connell MT, Terry N, DeCherney AH, Csokmay JM, et al. 2016. Intrauterine adhesion prevention after hysteroscopy: a systematic review and meta-analysis. American Journal of Obstetrics and Gynecology 215:267–275.e7.
  • Hooker A, Fraenk D, Brölmann H, Huirne J. 2016. Prevalence of intrauterine adhesions after termination of pregnancy: a systematic review. The European Journal of Contraception & Reproductive Health Care : The Official Journal of the European Society of Contraception 21:329–335.
  • Hu X, Dai Z, Pan R, Zhang Y, Liu L, Wang Y, et al. 2022. Long-term transplantation human menstrual blood mesenchymal stem cell loaded collagen scaffolds repair endometrium histological injury. Reproductive Toxicology (Elmsford, N.Y.) 109:53–60.
  • Jang HY, Myoung SM, Choe JM, Kim T, Cheon YP, Kim YM, et al. 2017. Effects of autologous platelet-rich plasma on regeneration of damaged endometrium in female rats. Yonsei Medical Journal 58:1195–1203.
  • Kaya C, Sever N, Cengiz H, Yıldız Ş, Ekin M, Yaşar L. 2014. A randomized controlled study of the efficacy of misoprostol and hyaluronic acid in preventing adhesion formation after gynecological surgery: a rat uterine horn model. European Journal of Obstetrics & Gynecology and Reproductive Biology 176:44–49.
  • Khrouf M, Morel O, Hafiz A, Chavatte-Palmer P, Fernandez H. 2012. Evaluation of the rabbit as an experimental model for human uterine synechia. Journal of Human Reproductive Sciences 5:175–180.
  • Kilic S, Yuksel B, Pinarli F, Albayrak A, Boztok B, Delibasi T. 2014. Effect of stem cell application on Asherman syndrome, an experimental rat model. Journal of Assisted Reproduction and Genetics 31:975–982.
  • Knight A. 2012. Assessing the necessity of chimpanzee experimentation. Altex 29:93–94.
  • Kong D, Zhang L, Xu X, Zhang J, Li Y, Huang X. 2018. Small intestine submucosa is a potential material for intrauterine adhesions treatment in a rat model. Gynecologic and Obstetric Investigation 83:499–507.
  • Lee WL, Liu CH, Cheng M, Chang WH, Liu WM, Wang PH. 2021. Focus on the primary prevention of intrauterine adhesions: current concept and vision. International Journal of Molecular Sciences 22:5175.
  • Li B, Zhang Q, Sun J, Lai D. 2019. Human amniotic epithelial cells improve fertility in an intrauterine adhesion mouse model. Stem Cell Research & Therapy 10:257.
  • Li J, Huang B, Dong L, Zhong Y, Huang Z. 2020. WJ‑MSCs intervention may relieve intrauterine adhesions in female rats via TGF‑β1‑mediated Rho/ROCK signaling inhibition. Molecular Medicine Reports 23:1–1.
  • Li L, Deng J, Lin L-M, Li Y-M, Lin Y, Xia B-H, et al. 2022. Metabolomics and pharmacodynamic analysis reveal the therapeutic role of Prunella vulgaris oil on intrauterine adhesion rats. Journal of Pharmaceutical and Biomedical Analysis 209:114532.
  • Liao Z, Liu C, Wang L, Sui C, Zhang H. 2021. Therapeutic role of mesenchymal stem cell-derived extracellular vesicles in female reproductive diseases. Frontiers in Endocrinology 12:665645.
  • Lin X, Zhang Y, Pan Y, He S, Dai Y, Zhu B, et al. 2018. Endometrial stem cell-derived granulocyte-colony stimulating factor attenuates endometrial fibrosis via sonic hedgehog transcriptional activator Gli2. Biology of Reproduction 98:480–490.
  • Liu F, Zhu ZJ, Li P, He YL. 2013. Creation of a female rabbit model for intrauterine adhesions using mechanical and infectious injury. Journal of Surgical Research 183:296–303.
  • Liu W, Pu L, Deng B, Xu H, Wang Z, Wang T, et al. 2020. Intermittent hypobaric hypoxia causes deleterious effects on the reproductive system in female rats. Biomedicine & Pharmacotherapy = Biomedecine & pharmacotherapie 130:110511.
  • Liu Y, Zhang S, Xue Z, Zhou X, Tong L, Liao J, et al. 2021. Bone mesenchymal stem cells-derived miR-223-3p-containing exosomes ameliorate lipopolysaccharide-induced acute uterine injury via interacting with endothelial progenitor cells. Bioengineered 12:10654–10665.
  • Ma X-L, Ding Y, Wu L-M, Wang Y-X, Yao Y, Wang Y-X, et al. 2021. The glucagon-like peptide-1 (GLP-1) analog exenatide ameliorates intrauterine adhesions in mice. Peptides 137:170481.
  • Salazar CA, Isaacson K, Morris S. 2017. A comprehensive review of Asherman’s syndrome: causes, symptoms and treatment options. Current Opinion in Obstetrics & Gynecology 29:249–256.
  • Sebbag L, Even M, Fay S, Naoura I, Revaux A, Carbonnel M, et al. 2019. Early second-look hysteroscopy: prevention and treatment of intrauterine post-surgical adhesions. Frontiers in Surgery 6:50.
  • Stamenov GS, Vitale SG, Della Corte L, Vilos GA, Parvanov DA, Nikolova DN, et al. 2020. Hysteroscopy and female infertility: a fresh look to a busy corner. Human Fertility 2020:1–29.
  • Wang S, Shi C, Cai X, Wang Y, Chen X, Han H, et al. 2021. Human acellular amniotic matrix with previously seeded umbilical cord mesenchymal stem cells restores endometrial function in a rat model of injury. Mediators of Inflammation 2021:5573594.
  • Wang X, Ma N, Sun Q, Huang C, Liu Y, Luo X. 2017. Elevated NF-κB signaling in Asherman syndrome patients and animal models. Oncotarget 8:15399–15406.
  • Wen J, Hou B, Lin W, Guo F, Cheng M, Zheng J, et al. 2022. 3D-printed hydrogel scaffold-loaded granulocyte colony-stimulating factor sustained-release microspheres and their effect on endometrial regeneration. Biomaterials Science 10:3346–3358.
  • Xiao HB, Sui GG, Lu XY, Sun ZL. 2018. Elevated levels of ADMA are associated with lower DDAH2 and higher PRMT1 in LPS-induced endometritis rats. Inflammation 41:299–306.
  • Xiao L, Song Y, Huang W, Yang S, Fu J, Feng X, et al. 2017. Expression of SOX2, NANOG and OCT4 in a mouse model of lipopolysaccharide-induced acute uterine injury and intrauterine adhesions. Reproductive Biology and Endocrinology : RB&E 15:14.
  • Xu C, Bao M, Fan X, Huang J, Zhu C, Xia W. 2022. EndMT: new findings on the origin of myofibroblasts in endometrial fibrosis of intrauterine adhesions. Reproductive Biology and Endocrinology : RB&E 20:9.
  • Xu Q-X, Zhang W-Q, Liu X-Z, Yan W-K, Lu L, Song S-S, et al. 2021. Notch1 signaling enhances collagen expression and fibrosis in mouse uterus. BioFactors (Oxford, England) 47:852–864.
  • Xu X-x, Cao L-b, Wang Z, Xu Z, Zhang B-q, Wu S-l, et al. 2018. Creation of a rabbit model for intrauterine adhesions using electrothermal injury. Journal of Zhejiang University-SCIENCE B 19:383–389.
  • Xu X-X, Zhang S-S, Lin H-L, Lin Q, Shen L-E, Ansong E, et al. 2019. Metformin promotes regeneration of the injured endometrium via inhibition of endoplasmic reticulum stress-induced apoptosis. Reproductive Sciences (Thousand Oaks, Calif.) 26:560–568.
  • Yang H, Wu S, Feng R, Huang J, Liu L, Liu F, et al. 2017. Vitamin C plus hydrogel facilitates bone marrow stromal cell-mediated endometrium regeneration in rats. Stem Cell Research & Therapy 8:267.
  • Yang L, Ma N, Song D, Huang X, Zhou Q, Guo Y, et al. 2022. The effect of estrogen in the prevention of adhesion reformation after hysteroscopic adhesiolysis: a prospective randomized control trial. Journal of Minimally Invasive Gynecology 29:871–878.
  • Zakaria R, Wan Yaacob WM, Othman Z, Long I, Ahmad AH, Al-Rahbi B. 2017. Lipopolysaccharide-induced memory impairment in rats: a model of Alzheimer’s disease. Physiological Research 66:553–565.
  • Zhang H, Xu D, Li Y, Lan J, Zhu Y, Cao J, et al. 2022. Organoid transplantation can improve reproductive prognosis by promoting endometrial repair in mice. International Journal of Biological Sciences 18:2627–2638.
  • Zhang J, Xiao C, Zhang X, Lin Y, Yang H, Zhang YS, et al. 2021. An oxidative stress-responsive electrospun polyester membrane capable of releasing anti-bacterial and anti-inflammatory agents for postoperative anti-adhesion. Journal of Controlled Release : Official Journal of the Controlled Release Society 335:359–368.
  • Zhang L, Li Y, Guan C-Y, Tian S, Lv X-D, Li J-H, et al. 2018. Therapeutic effect of human umbilical cord-derived mesenchymal stem cells on injured rat endometrium during its chronic phase. Stem Cell Research & Therapy 9:36.
  • Zhang L, Wang M, Zhang Q, Zhao W, Yang B, Shang H, et al. 2019. Estrogen therapy before hysteroscopic adhesiolysis improves the fertility outcome in patients with intrauterine adhesions. Archives of Gynecology and Obstetrics 300:933–939.
  • Zhang S, Sun Y, Jiang D, Chen T, Liu R, Li X, et al. 2021. Construction and optimization of an endometrial injury model in mice by transcervical ethanol perfusion. Reproductive Sciences (Thousand Oaks, Calif.) 28:693–702.
  • Zhang S-S, Xu X-X, Xiang W-W, Zhang H-H, Lin H-L, Shen L-E, et al. 2020. Using 17β-estradiol heparin-poloxamer thermosensitive hydrogel to enhance the endometrial regeneration and functional recovery of intrauterine adhesions in a rat model. FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology 34:446–457.
  • Zhao S, Qi W, Zheng J, Tian Y, Qi X, Kong D, et al. 2020. Exosomes derived from adipose mesenchymal stem cells restore functional endometrium in a rat model of intrauterine adhesions. Reproductive Sciences (Thousand Oaks, Calif.) 27:1266–1275.
  • Zhao Y-X, Chen S-R, Huang Q-Y, Chen W-C, Xia T, Shi Y-C, et al. 2021. Repair abilities of mouse autologous adipose-derived stem cells and ShakeGel™3D complex local injection with intrauterine adhesion by BMP7-Smad5 signaling pathway activation. Stem Cell Research & Therapy 12:191.
  • Zheng Y, Li L, Bi X, Xue R. 2022. circPTP4A2-miR-330-5p-PDK2 signaling facilitates in vivo survival of HuMSCs on SF-SIS scaffolds and improves the repair of damaged endometrium. Oxidative Medicine and Cellular Longevity 2022:2818433.
  • Zhu R, Gan L, Wang S, Duan H. 2019. A cohort study comparing the severity and outcome of intrauterine adhesiolysis for Asherman syndrome after first- or second-trimester termination of pregnancy. European Journal of Obstetrics, Gynecology, and Reproductive Biology 238:49–53.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.