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Journal of Obstetrics and Gynaecology Volume 18, 1998 - Issue 6
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Research Article

Efficacy of chloroquine plus chlorpheniramine in chloroquine-resistant falciparum malaria during pregnancy in Nigerian women: a preliminary study

A. SOWUNMI 1Department of Pharmacology and Therapeutics and Postgraduate Institute for Medical Research and Training; 2Department of Obstetrics and Gynaecology, University of Ibadan, Nigeria
Pages 524-527 | Published online: 02 Jul 2009

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  • Bray R. S. and Sinden R. E. (1979) The sequestration of Plasmodium falciparum infected erythrocytes in the placenta. Transactions of the Royal Society of Tropical Medicine and Hygiene, 73, 716-719.
  • Falade C. O., Salako L. A., Sowunmi A., Oduola A. M. J. and Larcier P. (1997) Comparative efficacy of halo-fantrine, chloroquine and sulphadoxine-pyrimethamine in treatment of acute uncomplicated falciparum malaria in Nigerian children. Transactions of the Royal Society of Tropical Medicine of Hygiene, 91, 58-62.
  • Fried A. M. and Duffy P. E. (1996) Adherence of Plasmodium falciparum to chondroitin sulfate A in the human placenta. Science, 272, 1502-1504.
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  • Rieckmann K. H., Campbell G. H., Sax M. J. and Mrema J. E. (1978) Drug sensitivity of Plasmodium falciparum: an in vitro microtechnique. Lancet, 1, 22-23.
  • Sowunmi A., Ilesanmi A. O., Oduola A. M. J., Omitowoju G. O. and Ojengbede O. A. (1996) Efficacy of mefloquine in uncomplicated chloroquine-resistant falciparum malaria during pregnancy. Journal of Obstetrics and Gynaecology, 16, 362-363.
  • Sowunmi A. and Oduola A. M. J. (1997) Comparative efficacy of chloroquine/chlorpheniramine combination and mefloquine for the treatment of chloroquine-resistant Plasmodium falciparum malaria in Nigerian children. Transactions of the Royal Society of Tropical Medicine and Hygiene, 91, 689-693.
  • Sowunmi A., Oduola A. M. J., Ogundahunsi O. A. T., Falade C. O., Gbotosho G. O. and Salako L. A. (1997) Enhanced efficacy of chloroquine/chlorpheniramine combination in acute uncomplicated falciparum malaria in children. Transactions of the Royal Society of Tropical Medicine and Hygiene, 91, 63-67.
  • Sowunmi A., Oduola A. M. J., Ogundahunsi O. A. T. and Salako L. A. (1998a) Enhancement of the antimalarial efficacy of chloroquine by chlorpheniramine in vivo. Tropical Medicine and International Health, in press.
  • Sowunmi A., Oduola A. M. J., Ogundahunsi O. A. T. and Salako L. A. (1998b) Comparative efficacy of chloroquine plus chlorpheniramine and pyrimethamine-sulphadoxine in acute uncomplicated falciparum malaria in Nigerian children. Transactions of the Royal Society of Tropical Medicine and Hygiene, 92, in press.
  • World Health Organisation Division of Control of Tropical Diseases (1990) Severe and complicated malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 84, supplement 2, 1-65.

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