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Biological Agriculture & Horticulture
An International Journal for Sustainable Production Systems
Volume 39, 2023 - Issue 4
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Review Article

Revision of Vitamin E recommendations for dairy cows in organic agriculture: a review-based approach

ORCID Icon & ORCID Icon
Pages 223-246 | Received 26 Apr 2022, Accepted 04 Apr 2023, Published online: 13 Apr 2023

References

  • Adler SA, Dahl AV, Jensen SK, Thuen E, Gustavsson A-M, Steinshamn H. 2013. Fatty acid composition, fat-soluble vitamin concentrations and oxidative stability in bovine milk produced on two pastures with different botanical composition. Livest Sci. 154(1–3):93–102. doi:10.1016/j.livsci.2013.03.013.
  • Aggarwal A, Ashutosh, Chandra G, Singh AK. 2013. Heat shock protein 70, oxidative stress, and antioxidant status in periparturient crossbred cows supplemented with α-tocopherol acetate. Trop Anim Health Prod. 45(1):239–245. doi:10.1007/s11250-012-0196-z.
  • Aggarwal A, Chandra G. 2011. Body condition score and lactation curve of crossbred cows supplemented with α -tocopherol acetate. Indian Vet J. 88:27–29.
  • Aggarwal A, Chandra G. 2018. The effect of additional supplementation of Vitamin E and Zinc on endocrine and metabolic changes in dairy cows during peripartal period. Vet Arh. 88(6):733–748. doi:10.24099/vet.arhiv.0059.
  • Al-Mabruk RM, Beck NFG, Dewhurst RJ, Beck NFG, Al-Mabruk RM, Dewhurst RJ, Dewhurst RJ, Al Mabruk RM, Beck NFG. 2004. Effects of silage species and supplemental vitamin E on the oxidative stability of milk. J Dairy Sci. 87(2):406–412. doi:10.3168/jds.S0022-0302(04)73180-X.
  • Amirifard R, Khorvash M, Forouzmand M, Rahmani HR, Riasi A, Malekkhahi M, Yari M, Hosseini-Ghaffari M. 2016. Performance and plasma concentration of metabolites in transition dairy cows supplemented with vitamin E and fat. J Integr Agric. 15(5):1076–1084. doi:10.1016/S2095-3119(15)61090-5.
  • Anderson JS, Sunderland R. 2002. Effect of extruder moisture and dryer processing temperature on vitamin C and E and astaxanthin stability. Aquaculture. 207(1–2):137–149. doi:10.1016/S0044-8486(01)00787-6.
  • Atkinson J, Thakur V, Manor D. 2019. The tocopherol transfer protein: regulator of vitamin E status. In: Vitamin E in human health. Springer International Publishing; p. 111–124. doi:10.1007/978-3-030-05315-4_9.
  • Atwal AS, Hidiroglou M, Kramer JKG. 1991. Effects of Feeding Protec® and α-Tocopherol on fatty acid composition and oxidative stability of cow’s milk. J Dairy Sci. 74(1):140–145. doi:10.3168/jds.S0022-0302(91)78154-X.
  • Atwal AS, Hidiroglou M, Kramer JKG, Binns MR. 1990. Effects of Feeding α-Tocopherol and calcium salts of fatty acids on Vitamin E and fatty acid composition of cow’s milk. J Dairy Sci. 73(10):2832–2841. doi:10.3168/jds.S0022-0302(90)78971-0.
  • Baldi A, Savoini G, Pinotti L, Monfardini E, Cheli F, Orto VD. 2000. Effects of Vitamin E and different energy sources on Vitamin E status, milk quality and reproduction in transition cows. J Vet Med Ser A. 47(10):599–608. doi:10.1046/j.1439-0442.2000.00323.x.
  • Ballet N, Robert JC, Williams PEV. 2000. Vitamins in forages. In: Givens D, Owen E, Axford R, and Omed H, editors. Forage Eval Rumin Nutr. Wallingford, UK: CAB International; p. 399–431.
  • Batra TR, Hidiroglou M, Smith MW. 1992. Effect of vitamin E on incidence of mastitis in dairy cattle. Can J Anim Sci. 72(2):287–297. doi:10.4141/cjas92-036.
  • Beeckman A, Vicca J, Van Ranst G, Janssens GPJ, Fievez V. 2010. Monitoring of vitamin E status of dry, early and mid-late lactating organic dairy cows fed conserved roughages during the indoor period and factors influencing forage vitamin E levels. J Anim Physiol Anim Nutr. 94(6):736–746. doi:10.1111/j.1439-0396.2009.00956.x.
  • Bell JA, Griinari JM, Kennelly JJ. 2006. Effect of safflower oil, flaxseed oil, monensin, and vitamin E on concentration of conjugated linoleic acid in bovine milk fat. J Dairy Sci. 89(2):733–748. doi:10.1093/jn/138.2.403.
  • Bieber A, Wallenbeck A, Leiber F, Fuerst-Waltl B, Winckler C, Gullstrand P, Walczak J, Wójcik P, Neff AS. 2019. Production level, fertility, health traits, and longevity in local and commercial dairy breeds under organic production conditions in Austria, Switzerland, Poland, and Sweden. J Dairy Sci. 102(6):5330–5341. doi:10.3168/jds.2018-16147.
  • Bludau MJ, Maeschli A, Leiber F, Steiner A, Klocke P. 2014. Mastitis in dairy heifers: prevalence and risk factors. Vet J. 202(3):566–572. doi:10.1016/j.tvjl.2014.09.021.
  • Bourne N, Laven R, Wathes DC, Martinez T, McGowan M. 2007. A meta-analysis of the effects of Vitamin E supplementation on the incidence of retained foetal membranes in dairy cows. Theriogenology. 67(3):494–501. doi:10.1016/j.theriogenology.2006.08.015.
  • Bourne N, Wathes DC, McGowan M, Laven R. 2007. A comparison of the effects of parenteral and oral administration of supplementary vitamin E on plasma vitamin E concentrations in dairy cows at different stages of lactation. null. 106(1):57–64. doi:10.1016/j.livsci.2006.07.001.
  • Bouwstra RJ, Goselink RMA, Dobbelaar P, Nielen M, Newbold JR, van Werven T. 2008. The relationship between oxidative damage and vitamin E concentration in blood, milk, and liver tissue from vitamin E supplemented and nonsupplemented periparturient heifers. J Dairy Sci. 91(3):977–987. doi:10.3168/jds.2007-0596.
  • Bouwstra RJ, Nielen M, Stegeman JA, Dobbelaar P, Newbold JR, Jansen EHJM, van Werven T. 2010. Vitamin E supplementation during the dry period in dairy cattle. Part I: adverse effect on incidence of mastitis postpartum in a double-blind randomized field trial. J Dairy Sci. 93(12):5684–5695. doi:10.3168/jds.2010-3159.
  • Bouwstra RJ, Nielen M, Van Werven T. 2009. Comparison of the oxidative status of vitamin E-supplemented and non-supplemented cows under field conditions. Tijdschr Diergeneeskd. 134(16):656–661.
  • Brzezinska-Slebodzinska E, Miller JK, Quigley JD III, Moore JR, Madsen FC. 1994. Antioxidant status of dairy cows supplemented prepartum with vitamin E and selenium. J Dairy Sci. 77(10):3087–3095. doi:10.3168/jds.s0022-0302(94)77251-9.
  • Brzóska F, Gąsior R, Sala K, Zyzak W. 1999. Effect of linseed oil fatty acid calcium salts andvitamin E on milk yield and composition. J Anim Feed Sci. 8(3):367–378. doi:10.22358/jafs/68942/1999.
  • Campbell MH, Miller JK. 1998. Effect of supplemental dietary vitamin E and zinc on reproductive performance of dairy cows and heifers fed excess iron. J Dairy Sci. 81(10):2693–2699. doi:10.3168/jds.S0022-0302(98)75826-6.
  • Chandra G, Aggarwal A, Kumar M, Singh AK. 2018. Effect of zinc and vitamin E supplementation on hormones and blood biochemicals in peri-partum Sahiwal cows. J Trace Elem Med Biol. 50:489–497. doi:10.1016/j.jtemb.2018.02.015.
  • Chandra G, Aggarwal A, Kumar M, Singh AK, Sharma VK, Upadhyay RC. 2014. Effect of additional vitamin E and zinc supplementation on immunological changes in peripartum Sahiwal cows. J Anim Physiol Anim Nutr. 98(6):1166–1175. doi:10.1111/jpn.12190.
  • Chandra G, Aggarwal A, Singh AK, Kumar M. 2012. TNF-alpha level and metabolic status in alpha-tocopheryl acetate supplemented high body condition periparturient crossbred cows during summer and winter. Indian J Anim Res. 82:999–1003.
  • Chandra G, Aggarwal A, Singh AK, Kumar M. 2015. Effect of vitamin E and zinc supplementation on milk yield, milk composition, and udder health in Sahiwal cows. Anim Nutr Feed Technol. 15(1):67–78. doi:10.5958/0974-181X.2015.00008.6.
  • Chandra G, Aggarwal A, Singh AK, Kumar M, Upadhyay RC. 2013. Effect of vitamin E and zinc supplementation on energy metabolites, lipid peroxidation, and milk production in peripartum sahiwal cows. Asian-Australas J Anim Sci. 26(11):1569–1576. doi:10.5713/ajas.2012.12682.
  • Charmley E, Nicholson JWG. 1994. Influence of dietary-fat source on oxidative stability and fatty-acid composition of milk from cows receiving a low or high level of dietary Vitamin-E. Can J Anim Sci. 74(4):657–664. doi:10.4141/cjas94-095.
  • Charmley E, Nicholson JWG, Zee JA. 1993. Effect of supplemental vitamin E and selenium in the diet on vitamin E and selenium levels and control of oxidized flavor in milk from Holstein cows. Can J Anim Sci. 73(2):453–457. doi:10.4141/cjas93-049.
  • Chatterjee PN, Kaur H, Kewalramani N, Tyagi AK. 2005. Influence of duration of prepartum and postpartum vitamin E supplementation on mastitis and milk yield in crossbred cows. Indian J Anim Sci. 75:503–507.
  • Chatterjee PN, Kaur H, Panda N. 2003. Effect of vitamin E supplementation on plasma antioxidant vitamins and immunity status of crossbred cows. Asian-Australas J Anim Sci. 16(11):1614–1618. doi:10.5713/ajas.2003.1614.
  • Chawla R, Kaur H. 2004. Plasma antioxidant vitamin status of periparturient cows supplemented with α-tocopherol and β-carotene. Anim Feed Sci Technol. 114(1–4):279–285. doi:10.1016/j.anifeedsci.2003.11.002.
  • Chawla R, Kaur H, Tyagi K. 2003. Influence of vitamin E and beta-carotene supplementation on spontaneous oxidised flavour of milk in dairy cows. Indian J Anim Sci. 73:807–811.
  • Dang AK, Prasad S, De K, Pal S, Mukherjee J, Sandeep IVR, Mutoni G, Pathan MM, Jamwal M, Kapila S, et al. 2013. Effect of supplementation of vitamin E, copper and zinc on the in vitro phagocytic activity and lymphocyte proliferation index of peripartum Sahiwal (Bos indicus) cows. J Anim Physiol Anim Nutr. 97(2):315–321. doi:10.1111/j.1439-0396.2011.01272.x.
  • Deaville ER, Givens DI, Blake JS. 2004. Dietary supplements of whole linseed and vitamin E to increase levels of alpha-linolenic acid and vitamin E in bovine milk. Anim Res. 53(1):3–12. doi:10.1051/animres:2003044.
  • De Luca AP, Teichman R, Rousseau JE Jr, Morgan ME, Eaton HD, Mac Leod P, Dicks MW, Johnson RE. 1957. Relative effectiveness of various antioxidants fed to lactating dairy Cows, on incidence of copper-induced oxidized milk flavor and on apparent carotene and tocopherol utilization. J Dairy Sci. 40(8):877–886. doi:10.3168/jds.S0022-0302(57)94570-8.
  • De K, Pal S, Prasad S, Dang AK. 2014. Effect of micronutrient supplementation on the immune function of crossbred dairy cows under semi-arid tropical environment. Trop Anim Health Prod. 46(1):203–211. doi:10.1007/s11250-013-0477-1.
  • Dobbelaar P, Bouwstra RJ, Goselink RMA, Jorritsma R, van den Borne JJGC, Jansen EHJM. 2010. Effects of vitamin E supplementation on and the association of body condition score with changes in peroxidative biomarkers and antioxidants around calving in dairy heifers. J Dairy Sci. 93(7):3103–3113. doi:10.3168/jds.2009-2677.
  • Dunkley WL, Franke AA, Robb J. 1968. Tocopherol concentration and oxidative stability of milk from cows fed supplements of d or dl-α-tocopheryl acetate. J Dairy Sci. 51(4):531–534. doi:10.3168/jds.S0022-0302(68)87024-9.
  • Dunkley WL, Ronning M, Franke AA, Robb J. 1967. Supplementing rations with tocopherol and ethoxyquin to increase oxidative stability of milk. J Dairy Sci. 50(4):492–499. doi:10.3168/jds.s0022-0302(67)87453-8.
  • Elgersma A, Søegaard K, Jensen SK. 2015. Interrelations between herbage yield, α-tocopherol, β-carotene, lutein, protein, and fiber in non-leguminous forbs, forage legumes, and a grass–clover mixture as affected by harvest date. J Agric Food Chem. 63(2):406–414. doi:10.1021/jf503658n.
  • European Commission. 2021. Commission Implementing Regulation (EU) 2021/1165 of 15 July 2021 authorising certain products and substances for use in organic production and establishing their lists. Off J Eur Communities. L 253:13–48.
  • European Parliament and the Council of the European Union. 2018. Regulation (EU) 2018/848 of the European Parliament and of the Council of 30 May 2018 on organic production and labelling of organic products and repealing Council Regulation (EC) No 834/2007. Off J Eur Union. 61:1–92.
  • Fauteux M-C, Gervais R, Rico DE, Lebeuf Y, Chouinard PY. 2016. Production, composition, and oxidative stability of milk highly enriched in polyunsaturated fatty acids from dairy cows fed alfalfa protein concentrate or supplemental vitamin E. J Dairy Sci. 99(6):4411–4426. doi:10.3168/jds.2015-10722.
  • FDA 2019. Converting units of measure for Folate, Niacin, and Vitamins A, D, and E on the nutrition and supplement facts labels: guidance for Industry. U.S. Department of Health and Human Services Food and Drug Administration Center for Food Safety and Applied Nutrition. p. 31.
  • Ferlay A, Martin B, Lerch S, Gobert M, Pradel P, Chilliard Y. 2010. Effects of supplementation of maize silage diets with extruded linseed, vitamin E and plant extracts rich in polyphenols, and morning v. evening milking on milk fatty acid profiles in Holstein and Montbéliarde cows. Animal. 4:627–640. doi:10.1017/S1751731109991224.
  • Firth CL, Laubichler C, Schleicher C, Fuchs K, Käsbohrer A, Egger-Danner C, Köfer J, Obritzhauser W. 2019. Relationship between the probability of veterinary-diagnosed bovine mastitis occurring and farm management risk factors on small dairy farms in Austria. J Dairy Sci. 102(5):4452–4463. doi:10.3168/jds.2018-15657.
  • Focant M, Mignolet E, Marique M, Clabots F, Breyne T, Dalemans D, Larondelle Y. 1998. The effect of vitamin E supplementation of cow diets containing rapeseed and linseed on the prevention of milk fat oxidation. J Dairy Sci. 81(4):1095–1101. doi:10.3168/jds.S0022-0302(98)75671-1.
  • Givens DI, Allison R, Blake JS. 2003. Enhancement of oleic acid and vitamin E concentrations of bovine milk using dietary supplements of whole rapeseed and vitamin E. Anim Res. 52(6):531–542. doi:10.1051/animres:2003039.
  • Gobert M, Martin B, Ferlay A, Chilliard Y, Graulet B, Pradel P, Bauchart D, Durand D. 2009. Plant polyphenols associated with vitamin E can reduce plasma lipoperoxidation in dairy cows given n-3 polyunsaturated fatty acids. J Dairy Sci. 92(12):6095–6104. doi:10.3168/jds.2009-2087.
  • Govasmark E, Steen A, Strøm T, Hansen S, Ram Singh B, Bernhoft A. 2005. Status of selenium and vitamin E on Norwegian organic sheep and dairy cattle farms. Acta Agric Scand Sect A - Anim Sci. 55(1):40–46. doi:10.1080/09064700510009298.
  • Graulet B, Piquet M, Duriot B, Pradel P, Hulin S, Cornu A, Portelli J, Martin B, Farruggia A. 2012. Variations des teneurs en micronutriments de l’herbe des prairies de moyenne montagne et transfert au lait. Fourrages. 209:59–68.
  • Gullickson TW, Fitch JB, Gilmore LO. 1948. Effect of feeding tocopherols to dairy cows on the quantity and the fat content of milk produced. J Dairy Sci. 31(7):557–560. doi:10.3168/jds.S0022-0302(48)92242-5.
  • Hakkarainen J, Pehrson B. 1987. Vitamin E and polyunsaturated fatty acids in Swedish feedstuffs for cattle. Acta Agric Scand. 37(3):341–346. doi:10.1080/00015128709436566.
  • Hamilton C, Emanuelson U, Forslund K, Hansson I, Ekman T. 2006. Mastitis and related management factors in certified organic dairy herds in Sweden. Acta Vet Scand. 48(1):11. doi:10.1186/1751-0147-48-11.
  • Hardeng F, Edge V. 2001. Mastitis, ketosis, and milk fever in 31 organic and 93 conventional Norwegian dairy herds. J Dairy Sci. 84(12):2673–2679. doi:10.3168/jds.S0022-0302(01)74721-2.
  • Harrison JH, Hancock DD, Conrad HR. 1984. Vitamin E and selenium for reproduction of the dairy cow. J Dairy Sci. 67(1):123–132. doi:10.3168/jds.S0022-0302(84)81275-8.
  • Harrison JH, Hancock DD, Pierre N, Conrad HR, Harvey WR. 1986. Effect of pepartum selenium treatment on uterine involution in the dairy cow. J Dairy Sci. 69(5):1421–1425. doi:10.3168/jds.S0022-0302(86)80550-1.
  • Herdt TH, Smith JC. 1996. Blood-lipid and lactation-stage factors affecting serum vitamin E concentrations and vitamin E cholesterol ratios in dairy cattle. J Vet Diagn Invest. 8(2):228–232. doi:10.1177/104063879600800213.
  • Hidiroglou M, Batra TR, Nielsen KH. 1992. Effect of vitamin E supplementation and of health status of mammary gland on immunoglobulin concentration in milk of dairy cows. Ann Rech Vet. 23(2):139–144.
  • Hidiroglou M, Batra T, Roy G. 1994. Changes in plasma α-Tocopherol and selenium of gestating cows fed hay or silage. J Dairy Sci. 77(1):190–195. doi:10.1016/0921-4488(96)00869-3.
  • Hidiroglou M, Batra T, Zhao X. 1997. Bioavailability of vitamin E compounds and the effect of supplementation on release of superoxide and hydrogen peroxide by bovine neutrophils. J Dairy Sci. 80:187–193.
  • Hidiroglou N, Cave N, Atwall AS, Farnworth ER, McDowell LR. 1992. Comparative vitamin E requirements and metabolism in livestock. Ann Rech Vet. 23:337–359.
  • Hidiroglou N, McDowell LR, Papas AM, Antapli M, Wilkinson NS. 1992. Bioavailability of vitamin E compounds in lambs. J Anim Sci. 70:2556–2561.
  • Hidiroglou M, Wauthy JM, Proulx JE. 1976. [Vitamin E activity of stored forages and incidence of myopathy in calves]. Ann Rech Vet. 7(2):185–194.
  • Hogan JS, Smith KL, Weiss WP, Todhunter DA, Schockey WL. 1990. Relationships among Vitamin E, selenium, and bovine blood neutrophils. J Dairy Sci. 73:2372–2378. doi:10.3168/jds.S0022-0302(90)78920-5.
  • Hogan JSS, Weiss WPP, Smith KLL. 1993. Role of vitamin E and selenium in host defense against mastitis. J Dairy Sci. 76:2795–2803. doi:10.3168/jds.S0022-0302(93)77618-3.
  • Hogan JS, Weiss WP, Todhunter DA, Smith KL, Schoenberger PS. 1992. Bovine neutrophil responses to parenteral vitamin E. J Dairy Sci. 75:399–405. doi:10.3168/jds.S0022-0302(92)77775-3.
  • Höjer A, Adler S, Martinsson K, Jensen SK, Steinhsamn H, Thuen T, Gustavsson A-M. 2012. Effect of legume–grass silages and a-tocopherol supplementation on fatty acid composition and a-tocopherol, b-carotene and retinol concentrations in organically produced bovine milk. Livest Sci. 148:268–281. doi:10.1016/j.livsci.2012.06.016.
  • INRA. 2018. INRA feeding systems for ruminants. Wageningen, the Netherlands: Wageningen Academic Publishers.
  • INRA-CIRAD-AFZ. 2017–2021. INRA-CIRAD-AFZ feed tables. Composition and nutritive values of feeds for cattle, sheep, goats, pigs, poultry, rabbits, horses and salmonids. https://feedtables.com/
  • Ivemeyer S, Smolders G, Brinkmann J, Gratzer E, Hansen B, Henriksen BIF, Huber J, Leeb C, March S, Mejdell C, et al. 2012. Impact of animal health and welfare planning on medicine use, herd health and production in European organic dairy farms. null. 145:63–72. doi:10.1016/j.livsci.2011.12.023.
  • Ivemeyer S, Walkenhorst M, Heil F, Notz C, Maeschli A, Butler G, Klocke P. 2009. Management factors affecting udder health and effects of a one year extension program in organic dairy herds. Animal. 3:1596–1604. doi:10.1017/S1751731109990498.
  • Jackson JA, Harmon RJ, Tabeidi Z. 1997. Effect of dietary supplementation with Vitamin E for lactating dairy cows fed tall fescue hay infected with endophyte. J Dairy Sci. 80:569–572. doi:10.3168/jds.S0022-0302(97)75972-1.
  • Jensen SK. 2003. Malkekoens vitaminbehov og -forsyning. In: Strudsholm F, Sejrsen K, editors. Kvægets ernæring og Fysiol Bind 2-Fodring og produktion. Tjele: Danmarks Jordbrugsforskning; p. 180–188. DJF Rapport 54.
  • Jensen SK, Lauridsen C. 2007. Alpha-tocopherol stereoisomers. Vitam Horm. 76:281–308. doi:10.1016/S0083-6729(07)76010-7.
  • Johansson B, Persson Waller K, Jensen SK, Lindqvist H, Nadeau E. 2014. Status of vitamins E and a and β-carotene and health in organic dairy cows fed a diet without synthetic vitamins. J Dairy Sci. 97:1682–1692. doi:10.3168/jds.2013-7388.
  • Jukola E, Hakkarainen J, Saloniemi H, Sankari S. 1996. Blood selenium, vitamin E, vitamin A, and b-carotene concentrations and udder health, fertility treatments, and fertility. J Dairy Sci. 79:838–845. doi:10.3168/jds.S0022-0302(96)76432-9.
  • Kay JK, Roche JR, Kolver ES, Thomson NA, Baumgard LH. 2005. A comparison between feeding systems (pasture and TMR) and the effect of vitamin E supplementation on plasma and milk fatty acid profiles in dairy cows. J Dairy Res. 72:322–332. doi:10.1017/S0022029905000944.
  • Khodamoradi SH, Fatahnia F, Taherpour K, Pirani V, Rashidi L, Azarfar A. 2013. Effect of monensin and vitamin E on milk production and composition of lactating dairy cows. J Anim Physiol Anim Nutr. 97:666–674. doi:10.1111/j.1439-0396.2012.01307.x.
  • Kidane A, Nesheim IL, Larsen HJS, Thuen E, Jensen SK, Steinshamn H. 2015. Effects of supplementing mid-lactation dairy cows with seaweed and vitamin E on plasma and milk α -tocopherol and antibody response to immunization. J Agric Sci. 153:929–942. doi:10.1017/S0021859615000052.
  • Krieger M, Sjöström K, Blanco-Penedo I, Madouasse A, Duval JE, Bareille N, Fourichon C, Sundrum A, Emanuelson U. 2017. Prevalence of production disease related indicators in organic dairy herds in four European countries. null. 198:104–108. doi:10.1016/j.livsci.2017.02.015.
  • Krukovsky VN, Loosli JK. 1952. Further studies on the influence of tocopherol supplementation on the vitamin content of the milk fat, stability of milk and milk and fat production. J Dairy Sci. 35:834–838. doi:10.3168/jds.S0022-0302(52)93764-8.
  • Lashkari S, Jensen SK, Bernes G. 2019. Biodiscrimination of alpha-tocopherol stereoisomers in plasma and tissues of lambs fed different proportions of all-rac-alpha-tocopheryl acetate and RRR-alpha-tocopheryl acetate. J Anim Sci. 97:1222–1233. doi:10.1093/jas/skz011.
  • Leiber F. 2022. Let them graze! Potentials of ruminant production outside the feed-food competition. In: El-Hage Scialabba N, editor. Managing healthy livestock production and consumption. London: Academic Press Elsevier; p. 137–148. doi:10.1016/B978-0-12-823019-0.00009-X.
  • Leiber F, Amsle Z, Bieber A, Quander-Stoll N, Maurer V, Lambertz C, Früh B, Ayrle H. 2022. Effects of riboflavin supplementation level on health, performance, and fertility of organic broiler parent stock and their chicks. Animal. 16:100433. doi:10.1016/j.animal.2021.100433.
  • Leiber F, Holinger M, Amsler Z, Maeschli A, Maurer V, Früh B, Lambertz C, Ayrle H. 2022. Riboflavin for laying hens fed organic winter diets: effects of different supplementation rates on health, performance and egg quality. Biol Agric Hortic. 38:1–16. doi:10.1080/01448765.2021.1955005.
  • Leiber F, Kreuzer M, Nigg D, Wettstein HR, Scheeder MRL. 2005. A study on the causes for the elevated n-3 fatty acids in cows’ milk of alpine origin. Lipids. 40:191–202.
  • Levison LJ, Miller-Cushon EK, Tucker AL, Bergeron R, Leslie KE, Barkema HW, DeVries TJ. 2016. Incidence rate of pathogen-specific clinical mastitis on conventional and organic Canadian dairy farms. J Dairy Sci. 99(2):1341–1350. doi:10.3168/jds.2015-9809.
  • Lindqvist H, Nadeau E, Jensen SK. 2012. A-tocopherol and b-carotene in legume-grass mixtures as influenced by wilting, ensiling and type of silage additive. Grass Forage Sci. 67:119–128. doi:10.1111/gfs.12058.
  • Lindqvist H, Nadeau E, Persson Waller K, Jensen SK, Johansson B. 2011. Effects of RRR-α-tocopheryl acetate supplementation during the transition period on vitamin status in blood and milk of organic dairy cows during lactation. null. 142:155–163. doi:10.1016/j.livsci.2011.07.009.
  • Liu Q, Lanari MC, Schaefer DM. 1995. A review of dietary Vitamin E supplementation for improvement of beef quality. J Anim Sci. 73:3131–3140. doi:10.2527/1995.73103131X.
  • Liu ZL, Yang DP, Chen P, Dong WX, Wang DM. 2008. Supplementation with selenium and vitamin E improves milk fat depression and fatty acid composition in dairy cows fed fat diet. Asian-Australas J Anim Sci. 21:838–844. doi:10.5713/ajas.2008.70618.
  • Lundin PK, Palmquist DL. 1983. Vitamin E supplementation of high fat diets for dairy cows. J Dairy Sci. 66:1909–1916. doi:10.3168/jds.S0022-0302(83)82029-3.
  • Maxin G, Cornu A, Andueza D, Laverroux S, Graulet B. 2020. Carotenoid, tocopherol, and phenolic compound content and composition in cover crops used as forage. J Agric Food Chem. 68:6286–6296. doi:10.1021/acs.jafc.0c01144.
  • McDowell LR, Williams SN, Hidiroglou N, Njeru CA, Hill GM, Ochoa L, Wilkinson NS. 1996. Vitamin E supplementation for the ruminant. Anim Feed Sci Technol. 60:273–296. doi:10.1016/0377-8401(96)00982-0.
  • McKay ZC, Mulligan FJ, Lynch MB, Rajauria G, Miller C, Pierce KM. 2019. The effects of cereal type and α-tocopherol level on milk production, milk composition, rumen fermentation, and nitrogen excretion of spring-calving dairy cows in late lactation. J Dairy Sci. 102:7118–7133. doi:10.3168/jds.2019-16270.
  • Meglia GE, Jensen SK, Lauridsen C, Waller KP. 2006. α-Tocopherol concentration and stereoisomer composition in plasma and milk from dairy cows fed natural or synthetic vitamin E around calving. J Dairy Res. 73:227–234. doi:10.1017/S0022029906001701.
  • Miller JK, Brzezinska-Slebodzinska E, Madsen FC. 1993. Oxidative stress, antioxidants, and animal function. J Dairy Sci. 76:2812–2823. doi:10.3168/jds.S0022-0302(93)77620-1.
  • Mogensen L, Kristensen T, Søegaard K, Jensen SK, Sehested J. 2012. Alfa-tocopherol and beta-carotene in roughages and milk in organic dairy herds. null. 145:44–54. doi:10.1016/j.livsci.2011.12.021.
  • Morales MS, Palmquist DL, Weiss WP. 2000. Milk fat composition of Holstein and Jersey cows with control or depleted copper status and fed whole soybeans or tallow. J Dairy Sci. 83:2112–2119. doi:10.3168/jds.S0022-0302(00)75093-4.
  • Müller CE, Möller J, Jensen SK, Uden P. 2007. Tocopherol and carotenoid levels in baled silage and haylage in relation to horse requiremnets. Anim Feed Sci Technol. 137:182–197. doi:10.1016/j.anifeedsci.2006.10.007.
  • National Academies of Sciences Engineering and Medicine. 2016. Nutrient Requirements of Beef Cattle: Eighth Revised Edition. Washington, DC: The National Academies Press. doi:10.17226/19014.
  • National Academies of Sciences Engineering and Medicine. 2021. Nutrient Requirements of Dairy Cattle: Eighth Revised Edition. Washington, DC: The National Academies Press. doi:10.17226/25806.
  • Nicholson JWG, Stlaurent AM. 1991. Effect of forage type and supplemental dietary vitamin E on milk oxidative stabilitv. Can J Anim Sci. 71:1181–1186.
  • Nicholson J, Stlaurent A, McQueen R, Charmley E. 1991. The effect of feeding organically bound selenium and alpha-tocopherol to dairy cows on susceptibility of milk oxidation. Can J Anim Sci. 71:135–143. doi:10.4141/cjas91-015.
  • NRC. 2001. Nutrient Requirements of Dairy Cattle: Seventh Revised. Washington, DC: The National Academies Press. doi:10.17226/9825.
  • NRC. 2007. Nutrient Requriements of Small ruminants. Sheep, goats, cervids, and new world camelids. Washington DC: National Academic Press.
  • O’Donnell-Megaro AM, Capper JL, Weiss WP, Bauman DE. 2012. Effect of linoleic acid and dietary vitamin E supplementation on sustained conjugated linoleic acid production in milk fat from dairy cows1. J Dairy Sci. 95:7299–7307. doi:10.3168/jds.2012-5802.
  • Politis I, Bizelis I, Tsiaras A, Baldi A. 2004. Effect of vitamin E supplementation on neutrophil function, milk composition and plasmin activity in dairy cows in a commercial herd. J Dairy Res. 71:273–278. doi:10.1017/S002202990400010X.
  • Politis I, Hidiroglou M, Batra TR, Gilmore JA, Gorewit RC, Scherf H. 1995. Effects of vitamin E on immune function of dairy cows. Am J Vet Res. 56:179–184.
  • Politis L, Hidiroglou N, Cheli F, Baldi A. 2001. Effects of vitamin E on urokinase-plasminogen activator receptor expression by bovine neutrophils. Am J Vet Res. 62(12):1934–1938. doi:10.2460/ajvr.2001.62.1934.
  • Politis I, Hidiroglou N, White JH, Gilmore JA, Williams SN, Scherf H, Frigg M. 1996. Effects of vitamin E on mammary and blood leukocyte function, with emphasis on chemotaxis, in periparturient dairy cows. Am J Vet Res. 57:468–471.
  • Politis I, Theodorou G, Lampidonis AD, Kominakis A, Baldi A. 2012. Short communication: oxidative status and incidence of mastitis relative to blood alpha-tocopherol concentrations in the postpartum period in dairy cows. J Dairy Sci. 95:7331–7335. doi:10.3168/jds.2012-5866.
  • Pottier J, Focant M, Debier C, De Buysser G, Goffe C, Mignolet E, Froidmont E, Larondelle Y. 2006. Effect of dietary vitamin E on rumen biohydrogenation pathways and milk fat depression in dairy cows fed high-fat diets. J Dairy Sci. 89:685–692. doi:10.3168/jds.S0022-0302(06)72131-2.
  • Quek S, Chu B, Baharin BS. 2007. Commercial extraction of vitamin E from food sources. In: Preedy V, and Watson R, editors. The encyclopedia of vitamin E. Wallingford: CAB International; p. 140–152.
  • Rahmani M, Dehghan-Banadaky M, Kamalyan R. 2015. Comparison between feeding rumen-protected choline and vitamin e on milk yield and blood metabolites in early lactation dairy cows. Anim Prod Sci. 55:752–757. doi:10.1071/AN14429.
  • Ramírez-Mella M, Hernández-Mendo O, Ramírez-Bribiesca EJ, Améndola-Massiotti RD, Crosby-Galván MM, Burgueño-Ferreira JA. 2013. Effect of vitamin E on milk composition of grazing dairy cows supplemented with microencapsulated conjugated linoleic acid. Trop Anim Health Prod. 45:1783–1788. doi:10.1071/AN14429.
  • Roesch M, Doherr MG, Schären W, Schällibaum M, Blum JW. 2007. Subclinical mastitis in dairy cows in Swiss organic and conventional production systems. J Dairy Res. 74:86–92. doi:10.1017/S002202990600210X.
  • Ruegg P. 2009. Management of mastitis on organic and conventional dairy farms. J Anim Sci. 87(13 suppl): 73-55. doi:10.2527/jas.2008-1217.
  • Santos FS, Zeoula LM, De Lima LS, De Marchi FE, Ítavo LCV, Santos NW, Pintro PM, Damasceno JC, Dos Santos GT. 2019. Effect of supplementation with yerba mate (Ilex paraguariensis) and Vitamin E on milk lipoperoxidation in cows receiving diets containing ground soybean seeds. J Dairy Res. 86:279–282. doi:10.1017/S0022029919000529.
  • Schäfers S, Meyer U, von Soosten D, Hüther L, Drong C, Eder K, Most E, Tröscher A, Pelletier W, Zeyner A, et al. 2018. Influence of conjugated linoleic acids and vitamin E on milk fatty acid composition and concentrations of vitamin a and α-tocopherol in blood and milk of dairy cows. J Anim Physiol Anim Nutr. 102:e431–441. doi:10.1111/jpn.12762.
  • Schäfers S, von Soosten D, Meyer U, Drong C, Frahm J, Kluess J, Raschka C, Rehage J, Tröscher A, Pelletier W, et al. 2017. Influence of conjugated linoleic acid and vitamin E on performance, energy metabolism, and change of fat depot mass in transitional dairy cows. J Dairy Sci. 100:3193–3208. doi:10.3168/jds.2016-11882.
  • Schäfers S, von Soosten D, Meyer U, Drong C, Frahm J, Tröscher A, Pelletier W, Sauerwein H, Dänicke S. 2018. Influence of conjugated linoleic acids and vitamin E on biochemical, hematological, and immunological variables of dairy cows during the transition period. J Dairy Sci. 101:1585–1600. doi:10.3168/jds.2017-13071.
  • Schingoethe DJ, Parsons JG, Ludens FC, Schaffer LV, Shave HJ. 1979. Response of lactating cows to 300 mg of supplemental vitamin E daily. J Dairy Sci. 62:333–338. doi:10.3168/jds.S0022-0302(79)83244-0.
  • Secrist DS, Owens FN, Gill DR, Boyd LJ, Oldfield JE. 1997. Effects of vitamin E on performance of feedlot cattle: a Review. Prof Anim Sci. 13:47–54. doi:10.15232/S1080-7446(15)31844-1.
  • Shingfield KJ, Salo-Väänänen P, Pahkala E, Toivonen V, Jaakkola S, Piironen V, Huhtanen P. 2005. Effect of forage conservation method, concentrate level and propylene glycol on the fatty acid composition and vitamin content of cows’ milk. J Dairy Res. 72:349–361. doi:10.1017/S0022029905000919.
  • Simpson MV, Hidiroglou M, Batra TR, Zhao X. 1998. Reduced level of creatine kinase in the plasma of Holstein cows supplemented with d-α-tocopherol acetate. Can J Anim Sci. 78:147–149. doi:10.4141/A97-042.
  • Singh AK, Bhakat C, Kumari T, Mandal DK, Chatterjee A, Karunakaran M, Dutta TK. 2020. Influence of pre and postpartum alpha-tocopherol supplementation on milk yield, milk quality, and udder health of Jersey crossbred cows at tropical lower Gangetic region. Vet World. 13:2006–2011. doi:10.14202/vetworld.2020.2006-2011.
  • Slots T, Skibsted LH, Nielsen JH. 2007. The difference in transfer of all-rac-alpha-tocopherol stereo-isomers to milk from cows and the effect on its oxidative stability. Int J Dairy Technol. 17:737–745. doi:10.1016/j.idairyj.2006.09.010.
  • Smith KL, Harrison JH, Hancock DD, Todhunter DA, Conrad HR. 1984. Effect of vitamin E and selenium supplementation on incidence of clinical mastitis and duration of clinical symptoms. J Dairy Sci. 67:1293–1300. doi:10.3168/jds.S0022-0302(84)81436-8.
  • Smith KL, Hogan JS, Weiss WP. 1997. Dietary vitamin E and selenium affect mastitis and milk quality. J Anim Sci. 75:1659–1665. doi:10.2527/1997.7561659x.
  • Stlaurent A, Hidiroglou M, Snoddon M, Nicholson J. 1990. Effect of alpha-tocopherol supplementation to dairy cows on milk and plasma alpha-tocopherol concentrations and spontaneous oxidized flavor in milk. Canadlian J Anim Sci. 70:561–570. doi:10.4141/cjas90-068.
  • Stowe HD, Thomas JW, Johnson T, Marteniuk JV, Morrow DA, Ullrey DE. 1988. Responses of dairy cattle to long-term and short-term supplementation with oral selenium and vitamin E. J Dairy Sci. 71:1830–1839. doi:10.3168/jds.S0022-0302(88)79752-0.
  • Tengerdy R. 1990. The Role of vitamin E in immune response and disease resistancea. Ann NY Acad Sci. 587:24–33. doi:10.1111/j.1749-6632.1990.tb00130.x.
  • Tian P, Niu D, Zuo S, Jiang D, Li R, Xu C. 2020. Vitamin a and E in the total mixed ration as influenced by ensiling and the type of herbage. Sci Total Environ. 746:141239. doi:10.1016/j.scitotenv.2020.141239.
  • Varga K, Fehér J, Trugly B, Drexler D, Leiber F, Verrastro V, Magid J, Chylinski C, Athanasiadou S, Thuerig B, et al. 2022. The State of Play of copper, mineral oil, external nutrient input, anthelmintics, antibiotics and vitamin usage and available reduction strategies in organic farming across Europe. Sustain. 14:3182. doi:10.3390/su14063182.
  • Volden H. 2011. NorFor-The Nordic feed evaluation system. Wageningen: Wageningen Academic Publishers.
  • Wallenbeck A, Rousing T, Sørensen JT, Bieber A, Spengler Neff A, Fuerst-Waltl B, Winckler C, Peiffer C, Steininger F, Simantke C, et al. 2019. Characteristics of organic dairy major farm types in seven European countries. Org Agric. 9:275–291. doi:10.1007/s13165-018-0227-9.
  • Waller KP, Sandgren CH, Emanuelson U, Jensen SK. 2007. Supplementation of RRR-{alpha}-tocopheryl acetate to periparturient dairy cows in commercial herds with high mastitis incidence. J Dairy Sci. 90:3640–3646. doi:10.3390/su14063182.
  • Weiss WP, Hogan JS, Smith KL, Todhunter DA, Williams SN. 1992. Effect of supplementing periparturient cows with vitamin E on distribution of α-tocopherol in blood. J Dairy Sci. 75:3479–3485. doi:10.3168/jds.S0022-0302(92)78124-7.
  • Weiss WP, Hogan JS, Smith KL, Williams SN. 1994. Effect of dietary fat and vitamin E on α-tocopherol and β-carotene in blood of peripartum cows. J Dairy Sci. 77:1422–1429. doi:10.3168/jds.S0022-0302(94)77080-6.
  • Weiss WP, Hogan JS, Todhunter DA, Smith KL. 1997. Effect of vitamin E supplementation in diets with a low concentration of selenium on mammary gland health of dairy cows. J Dairy Sci. 80:1728–1737. doi:10.3168/jds.S0022-0302(97)76105-8.
  • Weiss WP, Hogan JS, Wyatt DJ. 2009. Relative bioavailability of all-rac and RRR vitamin E based on neutrophil function and total {alpha}-tocopherol and isomer concentrations in periparturient dairy cows and their calves. J Dairy Sci. 92:720–731. doi:10.3168/jds.2008-1635.
  • Weiss WPP, Todhunter DAA, Hogan JSS, Smith KLL. 1990. Effect of duration of supplementation of selenium and vitamin E on periparturient dairy cows. J Dairy Sci. 73:3187–3194. doi:10.3168/jds.S0022-0302(90)79009-1.
  • Weiss WP, Wyatt DJ. 2003. Effect of dietary fat and vitamin E on α-tocopherol in milk from dairy cows. J Dairy Sci. 86:3582–3591. doi:10.3168/jds.S0022-0302(03)73964-2.
  • Whiting F, Loosli JK, Krukovsky VN, Turk KL. 1949. The influence of tocopherols and cod-liver oil on milk and fat production. J Dairy Sci. 32(2):133–138. doi:10.3168/jds.S0022-0302(49)92020-2.
  • Wichtel JJ, Craigie AL, Thompson KG, Williamson NB. 1996. Effect of selenium and A-tocopherol supplementation on postpartum reproductive function of dairy heifers at pasture. Theriogenology. 46(3):491–502. doi:10.1016/0093-691X(96)00171-9.
  • Witten S, Aulrich K. 2019. Exemplary calculations of native thiamine (vitamin B1) and riboflavin (vitamin B2) contents in common cereal-based diets for monogastric animals. Org Agric. 9(2):155–164. doi:10.1007/s13165-018-0219-9.
  • Zened A, Troegeler-Meynadier A, Najar T, Enjalbert F. 2012. Effects of oil and natural or synthetic vitamin E on ruminal and milk fatty acid profiles in cows receiving a high-starch diet. J Dairy Sci. 95(10):5916–5926. doi:10.3168/jds.2012-5326.