75
Views
0
CrossRef citations to date
0
Altmetric
Research Articles

Hepatoprotective effect of methanol fruit extract of Punica granatum L in highly active antiretroviral therapy-induced toxicity in Wistar rats

, , , , , , , & show all
Pages 243-251 | Received 05 Nov 2022, Accepted 01 Nov 2023, Published online: 01 Feb 2024

References

  • Abdel Moneim, A. E., & El-Khadragy, M. F. (2013). The potential effects of pomegranate (Punica granatum) juice on carbon tetrachloride-induced nephrotoxicity in Rats. Journal of Physiology and Biochemistry, 69(3), 359–370. https://doi.org/10.1007/s13105-012-0218-3
  • Afolabi, O., Oloyede, O., Olayide, I., Obafemi, T., Awe, O., Afolabi, B., & Onikani, A. (2015). Antioxidant enhancing ability of different solvents extractable components of Talinum triangulare in some selected Tissue homogenates of Albino rats -in vitro. Journal of Applied Pharmaceutical Science, 5(9), 056–061. https://doi.org/10.7324/JAPS.2015.50911
  • Alimoradian, A., Changizi-Ashtiyani, S., Farahani, A. G., Kheder, L., Rajabi, R., & Sharifi, A. (2017). Protective effects of pomegranate juice on nephrotoxicity induced by captopril and gentamicin in rats. Iran J Kidney Dis, 11(6), 422–429.
  • Aloqbi, A., Omar, U., Yousr, M., Grace, M., Lila, M. A., & Howell, N. (2016). Antioxidant activity of pomegranate juice and punicalagin. Natural Science, 08(06), 235–246. https://doi.org/10.4236/ns.2016.86028
  • Arhel, N., & Kirchhoff, F. (2010). Host proteins involved in HIV infection: New therapeutic targets. Biochimica et Biophysica Acta, 1802(3), 313–321. https://doi.org/10.1016/j.bbadis.2009.12.003
  • Baynes, H. W., Tegene, B., Gebremichael, M., Birhane, G., Kedir, W., & Biadgo, B. (2017). Assessment of the effect of antiretroviral therapy on renal and liver functions among hiv-infected patients: A retrospective study. HIV/AIDS (Auckland, N.Z.), 9, 1–7. https://doi.org/10.2147/HIV.S120979
  • Benedicto, A. M., Fuster-Mart, I., Tosca, J., Esplugues, J. V., Blas-Garc, A., & Apostolova, N. (2021). NNRTI and liver damage : Evidence of their association and the mechanisms involved. Cells, 10(7), 1687 https://doi.org/10.3390/cells10071687
  • Bhandari, P. (2012). Pomegranate (Punica granatum L). Ancient seeds for modern cure? Review of potential therapeutic applications. International Journal of Nutrition, Pharmacology, Neurological Diseases, 2(3), 171. https://doi.org/10.4103/2231-0738.99469
  • Bilgic, Y., Akbulut, S., Aksungur, Z., Erdemli, M. E., Ozhan, O., Parlakpinar, H., Vardi, N., & Turkoz, Y. (2018). Protective effect of dexpanthenol against cisplatin ‑ induced hepatotoxicity. Experimental and Therapeutic Medicine, 16(5), 4049–4057. https://doi.org/10.3892/etm.2018.6683
  • Calvani, M., Pasha, A., & Favre, C. (2020). Nutraceutical boom in cancer: Inside the labyrinth of reactive oxygen species. International Journal of Molecular Sciences, 21(6), 1936. https://doi.org/10.3390/ijms21061936
  • Cohen, G., Dembiec, D., & Marcus, J. (1970). Measurement of catalase activity in tissue extracts. Analytical Biochemistry, 34(1), 30–38. https://doi.org/10.1016/0003-2697(70)90083-7
  • El-Beshbishy, H. A., Tork, O. M., El-Bab, M. F., & Autifi, M. A. (2011). Antioxidant and antiapoptotic effects of green tea polyphenols against azathioprine-induced liver injury in rats. Pathophysiology: The Official Journal of the International Society for Pathophysiology, 18(2), 125–135. https://doi.org/10.1016/j.pathophys.2010.08.002
  • Erdemli, M. E., Gul, M., Altinoz, E., Aksungur, Z., Gul, S., & Bag, G. (2018). Can crocin play a preventive role in Wistar rats with carbon tetrachloride-induced nephrotoxicity? Journal of Basic Medical Sciences, 21(4), 382. https://doi.org/10.22038/IJBMS.2018.26101.6412
  • Esté, J. A., & Cihlar, T. (2010). Current status and challenges of antiretroviral research and therapy. Antiviral Research, 85(1), 25–33. https://doi.org/10.1016/j.antiviral.2009.10.007
  • Gil, L., Tarinas, A., Hernández, D., Riverón, B. V., Pérez, D., Tápanes, R., Capo, V., & Pérez, J. (2011). Altered oxidative stress indexes related to disease progression marker in human immunodeficiency virus infected patients with antiretroviral therapy. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 1(1), 8–15. https://doi.org/10.1016/j.biomag.2010.09.001
  • Jacinto, A. M. T. (2018). Review of the phytochemical, pharmacological and toxicological properties of Punica granatum L. Journal of the Science of Food and Agriculture, 2(3), 71–83. https://doi.org/10.26855/jsfa.2018.03.004
  • Kalemeera, F., Rennie, T., Godman, B., & Stergachis, A. (2020). Tenofovir disoproxil fumarate associated nephrotoxicity: A retrospective cohort study at two referral hospitals in Namibia. Pharmacoepidemiology and Drug Safety, 30(2), 189–200. https://doi.org/10.1002/pds.5125
  • Kalyesubula, R. (2011). Hepatotoxicity from first line antiretroviral therapy: An experience from a resource limited setting. Afr. Health Sci, 11(1), 16–23.
  • Kaspar, M. B., & Sterling, R. K. (2017). Mechanisms of liver disease in patients infected with HIV. BMJ Open Gastroenterology, 4(1), e000166 https://doi.org/10.1136/bmjgast-2017-000166
  • Lewis, W., Copeland, W. C., & Day, B. J. (2001). Mitochondrial DNA depletion, oxidative stress, and mutation: Mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors. Laboratory Investigation; a Journal of Technical Methods and Pathology, 81(6), 777–790. https://doi.org/10.1038/labinvest.3780288
  • Mandas, A., Iorio, E. L., Congiu, M. G., Balestrieri, C., Mereu, A., Cau, D., Dessì, S., & Curreli, N. (2009). Oxidative imbalance in HIV-1 infected patients treated with antiretroviral therapy. Journal of Biomedicine & Biotechnology, 2009, 749575–749577. https://doi.org/10.1155/2009/749575
  • Mebrat, Y., Amogne, W., Mekasha, A., & Seifu, (2017). Lipid Peroxidation and Altered Antioxidant Profiles with Pediatric HIV Infection and Antiretroviral Therapy in Addis Ababa, Ethiopia. Journal of Tropical Pediatrics, 63(3), 196–202. https://doi.org/10.1093/tropej/fmw076
  • Mestry, S. N., Gawali, N. B., Pai, S. A., Gursahani, M. S., Dhodi, J. B., Munshi, R., & Juvekar, A. R. (2020). Journal of ayurveda and integrative medicine Punica granatum improves renal function in gentamicin-induced nephropathy in rats via attenuation of oxidative stress. Journal of Ayurveda and Integrative Medicine, 11(1), 16–23. https://doi.org/10.1016/j.jaim.2017.09.006
  • Moga, M. A., Dimienescu, O. G., Bălan, A., Dima, L., Toma, S. I., Bîgiu, N. F., & Blidaru, A. (2021). Pharmacological and therapeutic properties of Punica granatum phytochemicals: Possible roles in breast cancer. Molecules (Basel, Switzerland), 26(4), 1–20. https://doi.org/10.3390/molecules26041054
  • Nair, A., & Jacob, S. (2016). A simple practice guide for dose conversion between animals and human. Journal of Basic and Clinical Pharmacy, 7(2), 27–31. https://doi.org/10.4103/0976-0105.177703
  • Offor, U., Coleridge, E., Olalekan, O., Isaac, A., Imo, A., & Okpara, O. (2018). Nephrotoxicity and highly active antiretroviral therapy : Mitigating action of Momordica charantia. Toxicology Reports, 5, 1153–1160. https://doi.org/10.1016/j.toxrep.2018.09.003
  • Otto, A. O., Rivera, C. G., Zeuli, J. D., & Temesgen, Z. (2021). Hepatotoxicity of contemporary antiretroviral drugs : A review and evaluation of published clinical data. Cells, 10(5), 1263 https://doi.org/10.3390/cells10051263
  • Panth, N., Manandhar, B., & Paudel, K. R. (2016). Anticancer activity of Punica granatum (Pomegranate): A review, 2017. https://doi.org/10.1002/ptr.5784
  • Prabhakar, P. V., Reddy, U. A., Singh, S. P., Balasubramanyam, A., Rahman, M. F., Indu Kumari, S., Agawane, S. B., Murty, U. S. N., Grover, P., & Mahboob, M. (2012). Oxidative stress induced by aluminum oxide nanomaterials after acute oral treatment in Wistar rats. Journal of Applied Toxicology: JAT, 32(6), 436–445. https://doi.org/10.1002/jat.1775
  • Rahman, S. A., Kadar, B. A., Taufik, M., & Baharuldin, H. (2015). Antidepressant-like effect of methanolic extract of Punica granatum (pomegranate) in mice model of depression. J Nat Prod Biomed Res, 22(3), 1670
  • Ramya, S., Narayanan, V., Ponnerulan, B., Saminathan, E., & Veeranan, U. (2020). Potential of peel extracts of Punica granatum and Citrus aurantifolia on alloxan- induced diabetic rats. Beni-Suef University Journal of Basic and Applied Sciences, 9(1), 24.https://doi.org/10.1186/s43088-020-00049-9
  • Sabraoui, T. (2020). Determination of punicalagins content, metal chelating, and antioxidant properties of edible pomegranate (Punica granatum L) peels and seeds grown in Morocco. International Journal of Food Science, 2020, 4–11.
  • Scarpino, M., & Santoro, M. (2015). HIV infection and kidney disease : Literature review. Infect. Dis. Trop. Med, 1(4), E195
  • Sharma, J., & Maity, A. (2010). Pomegranate phytochemicals: nutraceutical and therapeutic values. Fruit Veg Cereal Sci Biotechnol, 4(2), 56–76. [Online]. Available: http://www.globalsciencebooks.info/Online/GSBOnline/images/2010/FVCSB_4(SI2)/FVCSB_4(SI2)56-76o.pdf
  • Shaygannia, E., Bahmani, M., Zamanzad, B., & Rafieian-Kopaei, M. (2016). A review study on Punica granatum L. Journal of Evidence-Based Complementary & Alternative Medicine, 21(3), 221–227. https://doi.org/10.1177/2156587215598039
  • Singh, A., Bhat, T. K., & Sharma, O. P. (2011). Clinical biochemistry of hepatotoxicity journal of clinical toxicology. Journal of Clinical Microbiology, S4(001), 1–19. https://doi.org/10.4172/2161-0495.S4-001
  • Singh, B., Singh, J. P., Kaur, A., & Singh, N. (2018). Phenolic compounds as beneficial phytochemicals in pomegranate (Punica granatum L.) peel: A review. Food Chemistry, 261, 75–86. https://doi.org/10.1016/j.foodchem.2018.04.039
  • UNAIDS (2022). In danger: UNAIDS global AIDS update 2022. Geneva. Jt. United Nations Program. HIV/AIDS.
  • Viswanatha, G. L., & Venkataranganna, M. V. (2018). Methanolic leaf extract of Punica granatum attenuates ischemia- reperfusion brain injury in Wistar rats : Potential antioxidant and anti-inflammatory mechanisms. Iran J Basic Med Sci, 22, 187–196. https://doi.org/10.22038/ijbms.2018.30660.7389
  • Wei, X-l., Fang, R-t., Yang, Y-h., Bi, X-y., Ren, G-x., Luo, A-l., Zhao, M., & Zang, W-j. (2015). Protective effects of extracts from Pomegranate peels and seeds on liver fibrosis induced by carbon tetrachloride in rats. BMC Complementary and Alternative Medicine, 15(1), 1–9. https://doi.org/10.1186/s12906-015-0916-9
  • WHO (2019). Update of first- and second-line antiretroviral regimens. HIV Treat, no. July.
  • Williams, A. A., Sitole, L. J., & Meyer, D. (2017). Molecular BioSystems detectable by metabonomics. Molecular bioSystems, 13(11), 2202–2217. https://doi.org/10.1039/C7MB00336F
  • Zhao, L., Zhang, N., Yang, D., Yang, M., Guo, X., He, J., Wu, W., Ji, B., Cheng, Q., & Zhou, F. (2018). Protective effects of five structurally diverse flavonoid subgroups against chronic alcohol-induced hepatic damage in a mouse model. Nutrients, 10(11), 1754. https://doi.org/10.3390/nu10111754

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.