REFERENCES
- Weinbaurer GF, Rovan E, Frick J (1983): Toxicity of gossypol at antifertility dosages in male rats: statistical analyses of lethal rates and body weight responses. Andrologyia 15:213–221.
- Liu GZ (1987): Clinical studies of gossypol as a male contraceptive. Reproduction 5:189–192.
- Wsites GM, Wang C, Griffin PD (1998): Gossypol: reasons for its failure to be accepted as a safe reversible anti-fertility drug. Int J Androl 21:313–316.
- Elsimar MC (2002): Gossypol: a contraceptive for men. Contraception 65:259–263.
- Handelsman DJ, Farley TM, Peregoudov A, Waites GMH, WHO Task force on methods for the regulation of male fertility. (1995): Factors in the nonuniform induction of azoospermia by testosterone enanthate in normal men. Fertil Steril 63:125–133.
- Francea LR, Parreira GG, Gates RJ, Russell LD (1998): Hormonal regulation of spermatogenesis in the hypophysectomized rat: quantitation of germ cell population and effect of elimination of residual testosterone after long-term hypophysectomy. J Andro 19:335–342.
- Wu FC, Balasubramanian R, Mulders TM, Coelingh-Bennink HJ (1999): Oral progestogen combined with testosterone as a potential male contraceptive: Additive effects between desogestrel and testosterone enanthate in suppression of spermatogenesis, pituitary-testicular axis, and lipid metabolism. J Clin Endocrinol Metab 84:112–121.
- Cui GH, Xu ZL, Yang ZJ, Xu YY, Xue SP (2004): A combined regimen of gossypol plus methyltestosterone and ethinylestradiol as a contraceptive induces germ cell apoptosis and expression of its related genes in rats. Contraception 70:335–342.
- Yang ZJ, Ye WS, Cui GH, Guo Y, Xue SP (2004): Combined administration of low-dose gossypol acetic acid with desogestrel/mini-dose ethinylestradiol/testosterone undecanoate as an oral contraceptive for men. Contraception 70:203–211.
- Clouthier DE, Avarbock MR, Maika SD, Hammer RE, Brinster RL. (1996): Rat spermatogenesis in mouse testis. Nature 381:418–421.
- Wu DF (1989) An overview of the clinical pharmacology and therapeutic potential of gossypol as a male contraceptive agent and in gynecological disease. Drugs 38:333–341.
- Teng CS, Vilagrasa X (1998): Biphasic c-Myc protein expression during gossypol-induced apoptosis in rat spermatocytes. Contraception 57:117–123.
- Zhang X, Yamamoto N, Soramoto S, Takenaka I (2001): Cisplatin-induced germ cell apoptosis in mouse testes. Arch Androl 46(1):43–49.
- Shinhara T, Avarabock MR, Brinster RL (1999): α1 and β6-integrin are surface markers on mouse spermatogonial stem cells. Proc Natl Acad Sci 96:5504–5509.
- Shinhara T, Avarabock MR, Brinster RL (2000): Functional analysis of spermatogonial stem cells in steel and cryptorchid infertile mouse models. Dev Biol 220:401–411.
- Ogawa T, Dobrinski I, Avarbock MR, Brinster RL (1997): Transplantation of testis germinal cells into mouse seminiferous tubules. Int J Dev Biol 41:111–122.
- Ogawa T, Dobrinski I, Avarbock MR, Brinster RL (1999): Xenogeneic spermatogenesis following transplantation of Hamster germ cells to mouse testes. Biol Reprod 60:515–521.
- Brinster RL, Zimmermann JM (1994): Spermatogenisis following male germ-cell transplantation. Proc Natl Acad Sci USA 91:11298–11302.