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Neuro-Ophthalmology Volume 48, 2024 - Issue 1
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Original article

Septo-Optic Dysplasia: A Case Series of 33 Patients

Rohan NalawadeStrabismus Pediatric and Neuro-ophthalmology, Jasti V Ramanamma Children’s Eye Care Centre, L V Prasad Eye Institute, Hyderabad, IndiaView further author information
&
Manjushree BhateStrabismus Pediatric and Neuro-ophthalmology, Jasti V Ramanamma Children’s Eye Care Centre, L V Prasad Eye Institute, Hyderabad, IndiaCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0002-3826-3506View further author information
ORCID Icon
Pages 13-18 | Received 20 Feb 2023, Accepted 12 Oct 2023, Published online: 16 Nov 2023

References

  • de Morsier G. Studies on malformation of cranio-encephalic sutures. III. Agenesis of the septum lucidum with malformation of the optic tract. Schweiz Arch NeurolPsychiatr. 1956;77:267–292.
  • Ganau M, Huet S, Syrmos N, Meloni M, Jayamohan J. Neuro-ophthalmological manifestations of septo-optic dysplasia: current perspectives. Eye Brain. 2019;11:37–47. doi:10.2147/EB.S186307.
  • Miller SP, Shevell MI, Patenaude Y, Poulin C, O’Gorman AM. Septo-optic dysplasia plus: a spectrum of malformations of cortical development. Neurology. 2000;54(8):1701–1703. doi:10.1212/WNL.54.8.1701.
  • McCabe MJ, Alatzoglou KS, Dattani MT. Septo-optic dysplasia and other midline defects: the role of transcription factors: HESX1 and beyond. Best Pract Res Clin Endocrinol Metab. 2011;25(1):115–124. doi:10.1016/j.beem.2010.06.008.
  • Miller NM, Subramanian PS, Patel VR. Walsh and Hoyt’s clinical neuro-ophthalmology: The essentials. 4th ed. USA: Wolters Kluver; 2020.
  • Garne E, Rissmann A, Addor MC, et al. Epidemiology of septo-opticdysplasia with focus on prevalence and maternal age – a EUROCATstudy. Eur J Med Genet. 2018;61(9):483–488. doi:10.1016/j.ejmg.2018.05.010.
  • Khaper T, Bunge M, Clark I, et al. Increasing incidence of optic nerve hypoplasia/septo-optic dysplasia spectrum: geographic clustering in Northern Canada. Paediatr Child Health. 2017;22(8):445–453. doi:10.1093/pch/pxx118.
  • Tornqvist K, Ericsson A, Källén B. Optic nerve hypoplasia: risk factors and epidemiology. Acta Ophthalmol Scand. 2002;80(3):300–304. doi:10.1034/j.1600-0420.2002.800313.x.
  • Acers TE. Optic nerve hypoplasia: septo-optic-pituitary dysplasia syndrome. Trans Am Ophthalmol Soc. 1981;79:425–457.
  • Ryabets-Lienhard A, Stewart C, Borchert M, Geffner ME. The optic nerve hypoplasia spectrum: review of the literature and clinical guidelines. Adv Pediatr. 2016;63:127–146. doi:10.1016/j.yapd.2016.04.009.
  • Lubinsky MS. Hypothesis: septo-optic dysplasia is a vascular disruption sequence. Am J Med Genet. 1997;69(3):235–236. doi:10.1002/(SICI)1096-8628(19970331)69:3<235:AID-AJMG4>3.0.CO;2-K.
  • Alt C, Shevell MI, Poulin C, Rosenblatt B, Saint-Martin C, Srour M. Clinical and radiologic spectrum of septo-optic dysplasia: review of 17 cases. J Child Neurol. 2017;32(9):797–803. doi:10.1177/0883073817707300.
  • Borchert M. Reappraisal of the optic nerve hypoplasia syndrome. J Neuroophthalmol. 2012;32(1):58–67. doi:10.1097/WNO.0b013e31824442b8.
  • Kelberman D, Dattani MT. Septo-optic dysplasia–novel insights into the aetiology. Horm Res Paediatr. 2008;69(5):257–265. doi:10.1159/000114856.
  • O’Dwyer JA, Newton TH, Hoyt WF. Radiologic features of septooptic dysplasia: de morsier syndrome. Am J Neuroradiol. 1980;1:443–447.
  • Polizzi A, Pavone P, Iannetti P, Manfré L, Ruggieri M. Septo-optic dysplasia complex: a heterogeneous malformation syndrome. Pediatr Neurol. 2006;34(1):66–71. doi:10.1016/j.pediatrneurol.2005.07.004.
  • De Ferran K, Paiva IA, Gilban DL, et al. Septo-optic dysplasia. Arq NeuroPsiquiatr. 2010;68(3):400–405. doi:10.1590/S0004-282X2010000300014.
  • Qian X, Jain SF, Morgan LA, Kruse T, Cabrera M, Suh DW. Neuroimaging and endocrine disorders in paediatric optic nerve hypoplasia. Br J Ophthalmol. 2018;102(7):906–910. doi:10.1136/bjophthalmol-2017-310763.
  • Brodsky MC, Glasier CM. Optic nerve hypoplasia: clinical significance of associated central nervous system abnormalities on magnetic resonance imaging. Arch Ophthalmol. 1993;111(1):66–74. doi:10.1001/archopht.1993.01090010070029.

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