40
Views
2
CrossRef citations to date
0
Altmetric
Original

CELL LOSS IN THE INFERIOR OLIVE OF THE STAGGERER MUTANT MOUSE IS AN INDIRECT EFFECT OF THE GENE

, &
Pages 257-269 | Received 20 Oct 1989, Published online: 11 Jul 2009

References

  • Angaut, P., Alvarado-Mallarl, R. M. & Sotelo, C. (1982). Ultrastructural evidence for compensatory sprouting of climbing and mossy afferents to the cerebellar hemisphere after ipsilateral pedunculotomy in the newborn rat. J. Comp. Neurol., 205, 101–111.
  • Blatt, G. J. & Eisenman. L. M (1985). A quantitative and qualitative light microscopic study of the Inferior Olivary Complex in the adult staggerer mutant mouse. J. Neurogener., 2, 51–56.
  • Bradley, P. & Berry, M (1978). Purkinje cell dendritic tree in mutant mouse cerebellum. A quantitative Golgi study of weaver and staggerer mice. Brain Res., 142, 135–141.
  • Caddy, K. W. T. & Biscoe, T. J. (1979). Structural and quantitative studies on the normal C3H and lurcher mutant mouse. Phil. Trans. Roy. Soc. (Lond.) B, 287, 167–201.
  • Castro, A. J. (1978). Projections of the superior cerebellar peduncle in rats and the development of new connections in response to neonatal hemicerebellectomy. J. Comp. Neurol., 178, 611–628.
  • Clarke, P. G. H. (1985). Neuronal death during development in the isthmo-optic nucleus of the chick: sustaining role of afferents from the tectum. J. Comp. Neurol., 234, 365–379.
  • Clarke, P. G. H & Cowan, W. M. (1976). The development of the isthmo-optic tract in the chick, with special reference to the occurrence and correction of developmental errors in the location and connection of isthmo-optic neurons. J. Comp Neurol., 167, 143–64.
  • Courville, J., Augustine, J R & Martel, P. (1977). Projections from the inferior olive to the cerebellar nuclei in the cat demonstrated by retrograde transport of horseradish peroxidase. Brain Res., 130, 405–419.
  • Crepel, F., Delhaye-Bouchaud, N., Guastavino, J. M. & Sampaio, J. (1980). Multiple innvervation of cerebellar Purkinje cells by climbing fibers in staggerer mutant mouse. Nature (Lond.), 183, 483–484.
  • Ghetti, B., Norton, J. & Triarhou, L. (1987). Nerve cell atrophy and loss in the inferior olivary complex of Purkinje cell degeneration mutant mice. J. Comp. Neurol., 260, 409–422.
  • Goldowitz, D. & Mullen, R. J. (1982). Nuclear morphology of ichthyosis mutant mice as a cell marker in chimeric brain. Dev. Biol., 89, 261–267.
  • Harkmark, W. (1956). The influence of the cerebellum on development and maintenance of the inferior olive and the pons. An experimental investigation on chick embryo. J. Exp. Zool., 131, 333–360.
  • Hayashi, M., Nakajima, T. & Fishman, W. H. (1964). Distribution of β-glucuronidase activity in rat tissues employing the naphthol AS-BI glucuronide hexazonium pararosanalin method. J. Histochem. Cytochem., 12, 293–297.
  • Herrup. K. (1983). Role of staggerer gene in determining cell number in cerebellar cortex. II. Granule cell death and persistence of the external granule cell layer in young mouse chimeras. Dev. Brain Res., 12, 271–283.
  • Herrup, K. & Mullen, R J. (1979a). Regional variation and absence of large neurons in the cerebellum of the staggerer mouse, Brain Res., 172, 1–12.
  • Herrup, K. & Mullen, R. J. (1979b). Staggerer chimeras: Intrinsic nature of Purkinje cell defects and implications for normal cerebellar development. Brain Res., 178, 443–457.
  • Herrup, K. & Mullen, R. J. (1981). Role of the staggerer gene in determining Purkinje cell number in the cerebellar cortex of mouse chimeras. Dev. Brain Res., 1, 475–485.
  • Herrup, K. & Sunter, K. (1987). Numerical matching during cerebellar development: quantitative analysis of granule cell death in staggerer mouse chimera. J. Neurosci., 7, 829–836.
  • Herrup, K., Wetts, R. & Diglio, T. J. (1984b). Cell lineage relationships in the development of the mammalian CNS. II. Bilateral independence of CNS clones. J. Neurogenet., 1, 275–288.
  • Herrup, K., Diglio, T. J & Lctsou, A. (1984a). Cell lineage relationships in the development of the mammalian CNS: the facial nerve nucleus. Dev. Biol., 103, 329–336.
  • Lamb, A. H. (1981). Target dependency of developing motoneurons in Xenopus lacvis. J. Comp. Neurol., 203, 157–171.
  • Lamb, A. H. (1984). Motoneuron death in the embryo. Crit. Rev. Clin. Neurobiol., 1. 141–179.
  • Landis, D. M. D. & Sidman, R. L. (1978). Electron microscopic analysis of postnatal histogenesis in the cerebellar cortex of staggerer mutant mice. J. Comp. Neurol., 179, 831–863.
  • Lanser, M. E. & Fallon. J. F. (1984). Development of the lateral motor column in the limbless mutant chick embryo. J. Neurosci., 4, 2043–2050.
  • Lanser, M. E. & Fallon, J. F. (1987). Development of the brachial lateral motor column in the wingless mutant chick embryo: motoneuron survival under varying degrees of peripheral load. J. Comp. Nerol., 261, 423–434.
  • Mariani, J & Changcux, J. P. (1980). Multiple innervation of Purkinje cells by climbing fibers in the cerebellum of the adult staggerer mutant mouse. J. Neurohioi., 11, 41–50.
  • Mariani, J. & Delhaye-Bouchaud, N. (1987). Elimination of functional synapses during the development of the nervous system. News in Physiol. Sci., 1, 93–97.
  • Mariani, J. (1982). Extent of multiple innervation of Purkinje cells by climbing fibers in the olivocerebellar system of weaver, reeler and staggerer mutant mice. J. Neurohioi., 13, 119–126.
  • Mintz, B (1962). Formation of genotypically mosaic mouse embryos. Am. Zool., 2, 432.
  • Mintz, B. (1965). Genetic mosaicism in adult mice of quadriparental lineage. Science, 148, 1232–1233.
  • Mullen, R. J. (1977). Site of pcd gene action and Purkinje cell mosaicism in ccrebella of chimeric mice. Nature, 270, 245–247.
  • Mullen, R. J. & Whitten, W. K. (1971). Relationship of genotype and degree of chimerism in coat color to sex ratios and gametogenesis in chimeric mice. J. Exp. Zool., 178, 165–176.
  • Okado, N. & Oppenheim, R. W. (1984). Cell death of motoneurons in the chick embryo spinal cord. IX. The loss of motoneurons following removal of afferent input. J. Neurosci., 4, 1639–1652.
  • Oppenheim, R. W. (1985). Naturally occurring cell death during neural development. Trends Neurosci., 8, 487–493.
  • Parks, T. N. (1979). Afferent influences on the development of the brainstem auditory nuclei of the chicken: otocyst ablation. J. Comp. Neurol., 83, 665–678.
  • Roffler-Tarlov, S. & Herrup, K. (1981). Quantitative examination of the deep cerebellar nuclei in the staggerer mutant mice. Brain Res., 215, 49–59.
  • Shojaeian, H., Delhaye-Bouchaud, N. & Mariani, J. (1985). Decreased number of cell in Inferior Olivary Nucleus of the developing staggerer mouse. Dev. Brain Res., 21, 141–146.
  • Shojaeian, H., Mariani, J., Delhaye-Bouchaud, N & Bouchaud, N (1989). Olivary cell counts in nervous and leaner cerebellar mutant mice. Neurosci. Absct., 165, 437.
  • Shojaeian, H. (1987). Etude en cytologic quantitative de l’olive bulbaire des rongeurs: relation entre mort neuronale et elimination synaptique au cours du development et role des cellules cibles dans la regulation du nombre des neurones olivaires. Doctoral Thesis, Université Pierre et Marie Curie (Paris 6), Paris.
  • Shojaeian, H., Delhaye-Bouchaud, N. & Mariani, J. (1988). Stability of inferior olivary neurons in rodents. I. Moderate cell loss in adult Purkinje cell degeneration mutant mouse. Dev. Bruin Res., 38, 211–218.
  • Sidman, R. L., Lane, P. W & Dickie, M. M. (1962). Staggerer: a new mutation in the mouse affecting the cerebellum. Science, 137, 610–612.
  • Sidman, R. L. (1968). Development of interncuronal connection in brains of mutant mice. In F. D. Carlson (Ed.), Physiological and Biochemical Aspects of Nervous Integration, Prentice Hall, Englewood Cliffs, N.J., pp. 163–193.
  • Sidman, R. L .Green, M. L. and Appel, S. H. (1965). Catalogue of the neurological mutants of the mouse. Hardvard University Press, Cambridge, MA, pp. 66–67.
  • Soha, J M. & Hcrrup, K. (1989). Comparative morphology of +/+ Purkinje cell dendrites in staggerer, lurcher and wild type chimeric mice. Soc. Neurosci. Abst., 46, 102.
  • Sohal, G. S., Stoney, S. D. J., Arumugam, T. & Knox, T. S. (1986). Influence of reduced neuron pool on the magnitude of naturally occurring motor neuron death. J. Comp. Neurol., 247, 516–528.
  • Sonmez, E. & Herrup, K. (1984). Role of staggerer gene in determining cell number in cerebellar cortex, II. Granule cell death and persistence of the external granule cell layer in young mouse chimeras. Dev. Brain Res., 12, 271–283.
  • Sotelo, C. & Changeux, J. P (1974). Transsynaptic degeneration “en cascade” in the cerebellar cortex of staggerer mutant mice. Brain Res., 67, 519–526.
  • Tanaka, H. & Landmesser, L. (1986). Cell death of lumbosacral motoneurons in chick, quail, and chick-quail chimera embryos: a test of the quantitative matching hypothesis of neuronal cell death. J. Neurosci., 6, 2889–2899.
  • Tarkowski, A. K. (1961). Mouse chimeras developed from fused eggs. Nature, 230, 333–33.
  • Wetts, R & Wetts, R (1982b). Cerebellar Purkinje cells arc descended from a small number of progenitors committed during early development: quantitative analysis of lurcher chimeric mice. J. Neurosci., 2, 1494–1498.
  • Wetts, R. & Herrup, K. (1982a) Interaction of granule, Purkinje and inferior olivary neurons in lurcher chemeric mice, I. Qualitative studies. J. Embryol. Exp. Morph., 68, 87–98.
  • Williams, R. W. & Herrup. K. (1988). Control of cell number in the nervous system. Ann. Rev. Neurosci, 11, 423–453.
  • Yoon, C. H. (1972). Developmental mechanism for changes in cerebellum of staggerer mouse, a ncurological mutant of genetics origin. Neurology, 22, 743–754.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.