52
Views
0
CrossRef citations to date
0
Altmetric
Letters to the Editor

Electrophysiological and developmental implications of Na+ channel-splice variants

Pages 187-191 | Published online: 11 Jul 2009

References

  • Brackenbury W. J., Chioni A. M., Diss J. K. J., Djamgoz M. B. The neonatal splice variant of Nav1.5 potentiates in vitro invasive behaviour of MDA-MB-231 human breast cancer cells. Breast Cancer Res. Treat. 2007; 101: 149–160
  • Chioni A. M., Fraser S. P., Pani F., Foran P., Wilkin G. P., Diss J. K. J., Djamgoz M. B. A novel polyclonal antibody specific for the Nav1.5 voltage-gated Na+ channel “neonatal” isoform. J. Neurosci. Meth. 2005; 147: 88–98
  • Diss J. K. J., Fraser S. P., Djamgoz M. B. Voltage-gated Na+ channels: functional consequences of multiple subtypes and isoforms for physiology and pathophysiology. Eur. Biophys. J. 2004; 33: 180–193
  • Fraser S. P., Diss J. K. J., Coombes R. C., Djamgoz M. B. Expression of functional voltage-gated sodium ion channels in a metastatic human breast cancer cell line. J. Physiol. 2003; 549P: 7P–8P
  • Fraser S. P., Diss J. K. J., Chioni A. M., Mycielska M. E., Pan H., Yamaci R. F., Pani F., Siwy Z., Krakowska M., Grzywna Z., Brackenbury W. J., Theodorou D., Koyuturk M., Kaya H., Battaloglu E., Tamburo De Bella M., Slade M. J., Tolhurst R., Palmieri C., Jiang J., Latchman D. S., Coombes R. C., Djamgoz M. B. Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis. Clin. Cancer Res. 2005; 11: 5381–5389
  • Gustafson T. A., Clevinger E. C., Oneill T. J., Yarowsky P. J., Krueger B. K. Mutually exclusive exon splicing of type-III brain sodium channel-alpha subunit RNA generates developmentally regulated isoforms in rat-brain. J. Biol. Chem. 1993; 268: 18648–18653
  • Huang B., El-Sherif T., Gidh-Jain M., Qin D., El-Sherif N. Alterations of sodium channel kinetics and gene expression in the postinfarction remodeled myocardium. J. Cardiovasc. Electrophysiol. 2001; 12: 218–225
  • Monk M., Holding C. Human embryonic genes reexpressed in cancer cells. Oncogene 2001; 20: 8085–8091
  • Moody W. J., Bosma M. M. Ion channel development, spontaneous activity, and activity-dependent development in nerve and muscle cells. Physiol. Rev. 2005; 85: 883–941
  • Onkal, R., Mattis, J. H., Fraser, S. P., Diss, J. K., Shao, D., Okuse, K., & Djamgoz, M. B. 2008. Alternative splicing of Nav1.5: an electrophysiological comparison of “neonatal” and “adult” isoforms and critical involvement of a lysine residue. J. Cell. Physiol. [ Apr 4, Epub ahead of print].
  • Ou S. W., Kameyama A., Hao L. Y., Horiuchi M., Minobe E., Wang W. Y., Makita N., Kameyama M. Tetrodotoxin-resistant Na+ channels in human neuroblastoma cells are encoded by new variants of Nav1.5/SCN5A. Eur. J Neurosci. 2005; 22: 793–801
  • Roger S., Besson P., Le Guennec J. Y. Involvement of a novel fast inward sodium current in the invasion capacity of a breast cancer cell line. Biochim. Biophys. Acta. 2003; 1616: 107–111
  • Sarao R., Gupta S. K., Auld V. J., Dunn R. J. Developmentally regulated alternative RNA splicing of rat-brain sodium-channel messenger-RNAs. Nucleic Acids Res. 1991; 19: 5673–5679
  • Wang J., Ou S. W., Wang Y. J., Zong Z. H., Lin L., Kameyama M., Kameyama A. New variants of Nav1.5/SCN5A encode Na+ channels in the brain. J. Neurogenet. 2008; 22: 1–19
  • Ou S. W., Kameyama A., Hao L. Y., et al. Tetrodotoxin-resistant Na+ channels in human neuroblastoma cells are encoded by new variants of Nav1.5/SCN5A[J]. Eur. J. Neurosci. 2005; 22(4)793–801
  • Ou S. W., Zong Z. H., Wang J., et al. Nav1.5 Na+ channels in human brain are encoded by new variants of Nav1.5/SCN5A. Prog. Biochem. Biophys. 2007; 34(9)935–944
  • Ren C. T., Ou S. W., Wang Y. J., et al. Cloning and distribution analysis of Nav1.5 sodium channel in rat brain. Prog. Biochem. Biophys. 2007; 34(3)816–823
  • Wang, J., Wang, Y. J., Ou, S. W, et al. 2008. The expression of sodium channel mRNA in 16 different Wistar rat tissues of 5 different developmental stages. Chin. J. Biochem. Molec. Biol, in press.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.