Distinctions among electroconvulsion- and proconvulsant-induced seizure discharges and native motor patterns during flight and grooming: quantitative spike pattern analysis in Drosophila flight muscles

References

• Avila-Akerberg, O., & Charcon, M. (2011). Nonrenewal spike train statistics: Causes and functional consequences on neural coding. Experimental Brain Research, 210 (3–4), 353–371. doi:10.1007/s00221-011-2553-y
   PubMed Web of Science ®Google Scholar
• Bacci, A., & Huguenard, J. (2006). Enhancement of spike-timing precision by autaptic transmission in neocortical inhibitory interneurons. Neuron, 49, 119–130. doi:10.1016/j.neuron.2005.12.014
   PubMed Web of Science ®Google Scholar
• Benzer, S. (1971). From the gene to behavior. JAMA, 218, 1015–1022. doi:10.1001/jama.1971.03190200047010
   PubMed Web of Science ®Google Scholar
• Brembs, B., Christiansen, F., Pfluger, H., & Duch, C. (2007). Flight initiation and maintenance deficits in flies with genetically altered biogenic amine levels. Journal of Neuroscience, 27, 11122–11131. doi:10.1523/JNEUROSCI.2704-07.2007
   PubMed Web of Science ®Google Scholar
• Brennan, M., Palaniswami, M., & Kamen, P. (2001). Do existing measures of Poincare plot geometry reflect nonlinear features of heart rate variability? IEEE Transactions on Biomedical Engineering, 48, 1342–1347. doi:10.1109/10.959330
   PubMed Web of Science ®Google Scholar
• Card, G., & Dickinson, M. (2008). Visually mediated motor planning in the escape response of Drosophila. Current Biology, 18, 1300–1307. doi:10.1016/j.cub.2008.07.094
   PubMed Web of Science ®Google Scholar
• Chen, L., Durkin, K., & Casida, J. (2006). Structural model for gama-aminobutyric acid receptor noncompetitive anatagonist binding: Widely diverse structures fit the same site. Proceedings of the National Academy of Sciences of the United States of America, 103, 5185–5190. doi:10.1073/pnas.0600370103
   PubMed Web of Science ®Google Scholar
• Chen, X., Green, P., & Levine, J. (2011). Stress enhances muscle nociceptor activity in the rat. Neuroscience, 185, 166–173. doi:10.1016/j.neuroscience.2011.04.020
   PubMed Web of Science ®Google Scholar
• Coggshall, J. (1978). Neurons associated with the dorsal longitudinal flight muscles of Drosophila melanogaster. Journal of Comparative Neurology, 177, 707–720. doi:10.1002/cne.901770410
   PubMed Web of Science ®Google Scholar
• Consuolas, C., Restifo, L., & Levine, R. (2002). Dendritic remodeling and growth of motoneurons during metamorphosis of Drosophila melanogaster. Journal of Neuroscience, 22, 4906–4917. doi:10.1523/JNEUROSCI.22-12-04906.2002
   PubMed Web of Science ®Google Scholar
• Crompton, D., Griffin, A., Davies, J., & Miklos, G. (1992). Analysis of a cDNA from the neurologically active locus of shaking-B (Passover) of Drosophila melanogaster. Gene, 122, 385–386. doi:10.1016/0378-1119(92)90233-F
   PubMed Web of Science ®Google Scholar
• Curtsinger, J., & Laurie-Ahlberg, C. (1981). Genetic variability of flight matabolizm in Drosophila melanogaster. I. Characterization of power output during tethered flight. Genetics, 98, 549–564.
   PubMed Web of Science ®Google Scholar
• Dickinson, M., & Tu, M. (1997). The function of dipteran flight muscle. Comparative Biochemistry and Physiology Part A: Physiology, 116, 223–238. doi:10.1016/S0300-9629(96)00162-4
   PubMed Web of Science ®Google Scholar
• Ehaideb, S., Iyengar, A., Ueda, A., Iacobucci, G., Cranston, C., Bassuk, A., … Manak, J. (2014). Prickle modulates microdubule polarity and axonal transport to ameliorate seizures in flies. Proceedings of the National Academy of Sciences of the United States of America, 111, 11187–11192. doi:10.1073/pnas.1403357111
   PubMed Web of Science ®Google Scholar
• Elkins, T., & Ganetzky, B. (1988). The roles of potassium currents in Drosophila flight muscles. Journal of Neuroscience, 8, 428–434. doi:10.1523/JNEUROSCI.08-02-00428.1988
   PubMed Web of Science ®Google Scholar
• Elkins, T., Ganetzky, B., & Wu, C.F. (1986). A Drosophila mutation that eliminates a calcium-dependent potassium current. Proceedings of the National Academy of Sciences of the United States of America, 83, 8415–8419. doi:10.1073/pnas.83.21.8415
   PubMed Web of Science ®Google Scholar
• Engel, J., & Wu, C.F. (1992). Interactions of membrane excitability mutations affect potassium and sodium currents in the flight and giant fiber escape systems of Drosophila. Journal of Comparative Physiology A, 171, 93–104.
   PubMed Web of Science ®Google Scholar
• Engel, J., & Wu, C.F. (1996). Altered habituation of an identified escape circuit in Drosophila memory mutants. Journal of Neuroscience, 16, 3486–3499. doi:10.1523/JNEUROSCI.16-10-03486.1996
   PubMed Web of Science ®Google Scholar
• Engel, J., & Wu, C.F. (1998). Genetic dissection of functional contributions of specific potassium channel subunits in habituation of an escape circuit in Drosophila. Journal of Neuroscience, 18, 2254–2267. doi:10.1523/JNEUROSCI.18-06-02254.1998
   PubMed Web of Science ®Google Scholar
• Engel, J., Xie, X., Sokolowski, M., & Wu, C.F. (2000). A cGMP-dependent protein kinase gene, foraging, modifies habituation-like response decrement of the giant fiber escape circuit in Drosophil. Learning and Memory, 7, 341–352. doi:10.1101/lm.31600
   PubMed Web of Science ®Google Scholar
• Ewing, A. (1977). The neuromuscular basis of courtship song in Drosophila: The role of the indirect flight muscles. Journal of Comparative Physiology, 119, 249–265. doi:10.1007/BF00656637
   Web of Science ®Google Scholar
• Fergestad, T., Bostwick, B., & Ganetzky, B. (2006). Metabolic disruption in Drosophila bang-sensitive seizure mutants. Genetics, 173, 1357–1364. doi:10.1534/genetics.106.057463
   PubMedGoogle Scholar
• Fernandes, J., & VijayRaghavan, K. (1993). The development of indirect flight muscle innervation in Drosophila melanogaster. Development, 118, 215–227.
   Web of Science ®Google Scholar
• Ffrench-Constant, R., Mortlock, D., Shaffer, C., MacIntyre, R., & Roush, R. (1991). Molecular cloning and transformation of cyclodiene resistance in Drosophila: An invertibrate gamma-aminobutyric acid subtype A receptor locus. Proceedings of the National Academy of Sciences of the United States of America, 88, 7209–7213. doi:10.1073/pnas.88.16.7209
   PubMed Web of Science ®Google Scholar
• Ffrench-Constant, R., Williamson, M., Davies, T., & Bass, C. (2016). Ion channels as insecticide targets. Journal of Neurogenetics, 30, 163–177. doi:10.1080/01677063.2016.1229781
   PubMed Web of Science ®Google Scholar
• Frankel, A., & Brosseau, G. (1968). Drosophila medium that does not require dried yeast. Drosophila Information Service, 43, 184.
   Google Scholar
• Ganetzky, B., Wu, C.-F. (1982). Indirect suppression involving behavioral mutants iwht altered nerve excitability in Drosophila melanogaster. Genetics 100(4), 597–614.
   PubMed Web of Science ®Google Scholar
• Geier, S., Bancaud, J., Talairach, J., Bonis, A., Enjelvin, M., & Hossard-Bouchaud, H. (1976). Automatisms during frontal lobe epileptic seizures. Brain, 99, 447–458. doi:10.1093/brain/99.3.447
   PubMed Web of Science ®Google Scholar
• Ghezzi, A., Pohl, J., Wang, Y., & Atkinson, N. (2010). BK channels play a counter-adaptive role in drug tolerance and dependence. Proceedings of the National Academy of Sciences of the United States of America, 107, 16360–16365. doi:10.1073/pnas.1005439107
   PubMed Web of Science ®Google Scholar
• Giachello, C., & Baines, R. (2015). Inappropriate neural activity during a sensitive period in embryogenesis results in persistent seizure-like behavior. Current Biology, 25, 2964–2968. doi:10.1016/j.cub.2015.09.040
   PubMed Web of Science ®Google Scholar
• Goldberger, A., Rigney, D., & West, B. (1990). Chaos and fractals in human physiology. Scientific American, 262, 42–49. doi:10.1038/scientificamerican0290-42
   PubMed Web of Science ®Google Scholar
• Gorczyca, M., & Hall, J. (1984). Identification of a cholinergic synapse in the giant fiber pathway of Drosophila using conditional mutations of acetylcholine synthesis. Journal of Neurogenetics, 1, 289–313. doi:10.3109/01677068409107093
   PubMedGoogle Scholar
• Gordon, S., & Dickinson, M. (2006). Role of calcium in the regulation of mechanical power in insect flight. Proceedings of the National Academy of Sciences of the United States of America, 103, 4311–4315. doi:10.1073/pnas.0510109103
   PubMed Web of Science ®Google Scholar
• Greenspan, R., Finn, J., & Hall, J. (1980). Acetylcholinesterase mutants in Drosophila and their effects on the structure and function of the central nervous system. Journal of Comparative Neurology, 189, 741–744. doi:10.1002/cne.901890409
   PubMed Web of Science ®Google Scholar
• Grigliatti, T., Hall, L., Rosenbluth, R., Suzuki, D. (1973). Temperature-sensitive mutations in Drosophila melanogaster. Mol. Gen. Genet. 120(2), 107–114. doi:10.1007/BF00267238
   PubMedGoogle Scholar
• Harcombe, E., & Wyman, R. (1977). Output pattern generation by Drosophila flight motoneurons. Journal of Neurophysiology, 40, 1066–1077. doi:10.1152/jn.1977.40.5.1066
   PubMed Web of Science ®Google Scholar
• Harris, R., Pfeiffer, B., Rubin, G., Truman, J. (2015). Neuronal hemilineages provide the functional ground plan for the Drosophila ventral nervous system. eLife. 4 e03393. doi:10.7554/eLife.04493.
   PubMed Web of Science ®Google Scholar
• Hebbar, S., & Fernandes, J. (2004). Pruning of motor neuron branches establishes the DLM innervation pattern in Drosophila. Journal of Neurobiology, 60, 499–516. doi:10.1002/neu.20031
   PubMed Web of Science ®Google Scholar
• Hekmat-Scafe, D., Lundy, M., Ranga, R., & Tanouye, M. (2006). Mutations in the K+/Cl- cotransporter gene kazachoc (kcc) increase seizure susceptibility in Drosophila. Journal of Neuroscience, 26, 8943–8954. doi:10.1523/JNEUROSCI.4998-05.2006
   PubMed Web of Science ®Google Scholar
• Herrera-Valdez, M.A., McKiernan, E.C., Berger, S.D., Ryglewski, S., Duch, C., & Crook, S. (2013). Relating ion channel expression, bifurcation structure and diverse firing patterns in a model of an identified motor neuron. Journal of Computational Neuroscience, 34, 211–229. doi:10.1007/s10827-012-0416-6
   PubMed Web of Science ®Google Scholar
• Holt, G., Softky, W., Koch, C., & Douglas, R. (1996). Comparison of discharge variability in vitro and in vivo in cat visual cortex neurons. Journal of Neurophysiology, 75, 1806–1814. doi:10.1152/jn.1996.75.5.1806
   PubMed Web of Science ®Google Scholar
• Homyk, T., Grigliatti, T. (1983). Behavorial mutants of Drosophila melanogaster. IV. Analysis of developmentally temperature-sensitive mutations affecting flight. Dev. Genet. 4(2) 77–97. doi:10.1002/dvg.1020040204
   Google Scholar
• Homyk, T., Szidonya, J., & Suzuki, D. (1980). Behavioral mutants of Drosophila melanogaster. III. Isolation and mapping of mutations by direct visual observations of behavioral phenotypes. Molecular and General Genetics (MGG), 177, 553–565. doi:10.1007/BF00272663
   PubMed Web of Science ®Google Scholar
• Howlett, I., & Tanouye, M. (2013). Seizure-sensitivity in Drosophila is ameliorated by dorsal vessel injection of the antiepileptic drug valproate. Journal of Neurogenetics, 27, 143–150. doi:10.3109/01677063.2013.817574
   PubMed Web of Science ®Google Scholar
• Huikuri, H.V., Ma¨Kikallio, T.H., Peng, C.K., Goldberger, A.L., Hintze, U., & Møller, M. (2000). Fractal correlation properties of RR interval dynamics and mortality in patients with depressed left ventricular function after an acute myocardial infarction. Circulation, 101, 47–53. doi:10.1161/01.CIR.101.1.47
   PubMed Web of Science ®Google Scholar
• Ikeda, K., & Koenig, J. (1988). Morphological identification of the motor neurons innervating the dorsal longitudinal flight muscle of Drosophila melanogaster. Journal of Comparative Neurology A, 273, 436–444. doi:10.1002/cne.902730312
   PubMed Web of Science ®Google Scholar
• Iyengar, A., & Wu, C.F. (2014). Flight and seizure motor patterns in Drosophila mutants: Simultaneous acoustic and electrophysiological recordings of wing beats and flight muscle activity. Journal of Neurogenetics, 28, 316–328. doi:10.3109/01677063.2014.957827
   PubMed Web of Science ®Google Scholar
• Jackson, F., Wilson, S., Strichartz, G., Hall, L. (1984). Two types of mutants affecting voltage-sensitive sodium channels in Drosophila melanogaster. Nature 308(5955), 189–191. doi:10.1038/308189a0
   Web of Science ®Google Scholar
• Jasper, H. (1964). Some physiological mechanisms involved in epileptic automatisms. Epilepsia, 5, 1–20. doi:10.1111/j.1528-1157.1964.tb04341.x
   PubMed Web of Science ®Google Scholar
• Judd, B., Shen, M., & Kaufman, T. (1972). The anatomy and function of a segment of the X chromosome of Drosophila melanogaster. Genetics, 71, 139–156.
   PubMed Web of Science ®Google Scholar
• Kadas, D., Tzortzopoulos, A., Skoulakis, E.M.C., & Consoulas, C. (2012). Constitutive activation of Ca2+/calmodulain dependent protein kinase II during development impairs central cholinergic transmission in a circuit underlying escape behavior in Drosophila. Journal of Neuroscience, 32, 170–182. doi:10.1523/JNEUROSCI.6583-10.2012
   PubMed Web of Science ®Google Scholar
• Kaplan, W., & Trout, W. (1969). The behavior of four neurological mutants of Drosophila. The Genetics, 61, 399–409.
   PubMed Web of Science ®Google Scholar
• Kawasaki, F., Felling, R., & Ordway, R. (2000). A temperature-sensitive paralytic mutant defines a primary synaptic calcium channel in Drosophila. Journal of Neuroscience, 20, 4885–4889. doi:10.1523/JNEUROSCI.20-13-04885.2000
   PubMed Web of Science ®Google Scholar
• King, D., & Wyman, R. (1980). Anatomy of the giant fiber pathway in Drosophila. I. Three thoracic components of the pathway. Journal of Neuroscience, 9, 753–770. doi:10.1007/BF01205017
   Web of Science ®Google Scholar
• Knight, B. (1972). Dynamics of encoding in a population of neurons. The Journal of General Physiolog, 59, 734–766. doi:10.1085/jgp.59.6.734
   PubMed Web of Science ®Google Scholar
• Koenig, J., & Ikeda, K. (1980). Neural interactions controlling timing of flight muscle activity in Drosophila. Journal of Experimental Biology, 87, 121–136.
   PubMed Web of Science ®Google Scholar
• Kuebler, D., & Tanouye, M. (2000). Modifications of seizure susceptibility in Drosophila. Journal of Neurophysiology, 83, 998–1009. doi:10.1152/jn.2000.83.2.998
   PubMed Web of Science ®Google Scholar
• Kuebler, D., Zhang, H., Ren, X., & Tanouye, M. (2001). Genetic suppression of seizure susceptibility in Drosophila. Journal of Neurophysiology, 86, 1211–1225. doi:10.1152/jn.2001.86.3.1211
   PubMed Web of Science ®Google Scholar
• Lansky, P., Rodriguez, R., & Sacerdote, L. (2004). Mean instantaneous firing frequency is always higher than the firing rate. Neural Computation, 16, 477–489. doi:10.1162/089976604772744875
   PubMed Web of Science ®Google Scholar
• Lee, D., Su, H., & O’Dowd, D.K. (2003). GABA receptors containing Rdl subunits mediate fast inhibitory synaptic transmission in Drosophila neurons. Journal of Neuroscience, 23, 4625–4634. doi:10.1523/JNEUROSCI.23-11-04625.2003
   PubMed Web of Science ®Google Scholar
• Lee, J., & Wu, C.F. (2002). Electroconvulsive seizure behavior in Drosophila: Analysis of the physiological repertoire underlying a stereotyped action pattern in bang-sensitive mutants. Journal of Neuroscience, 22, 11065–11079. doi:10.1523/JNEUROSCI.22-24-11065.2002
   PubMed Web of Science ®Google Scholar
• Lee, J., & Wu, C.F. (2006). Genetic modifications of seizure susceptivility and expression by altered excitability in Drosophila Na.+ and K.+ channel mutants. Journal of Neurophysiology, 96, 2465–2478. doi:10.1152/jn.00499.2006
   PubMed Web of Science ®Google Scholar
• Lehman, F.O., Skandalis, D., & Berthe, R. (2013). Calcium signalling indicates bilateral power balancing in the Drosophila fligth muscle during manoeuvring flight. Journal of the Royal Society Interface, 10, 1050.
   Web of Science ®Google Scholar
• Lehmann, F.O., & Dickinson, M. (1997). The changes in power requirements and muscle efficiency during elevated force production in the fruit fly Drosophila melanogaster. Journal of Experimental Biology, 200, 1133–1143.
   PubMed Web of Science ®Google Scholar
• Levine, J., & Wyman, R. (1973). Neurophysiology of flight in wild-type and a mutant Drosophila. Proceedings of the National Academy of Sciences of the United States of America, 70, 1050–1054. doi:10.1073/pnas.70.4.1050
   PubMed Web of Science ®Google Scholar
• Lindsley, D., & Zimm, G. (1992). The genome of Drosophila. San Diego, CA: Academic Press.
   Google Scholar
• Liu, W., & Wilson, R. (2013). Glutamate is an inhibitor neurotransmitter in the Drosophila olfactory system. Proceedings of the National Academy of Sciences of the United States of America, 110, 10294–10299. doi:10.1073/pnas.1220560110
   PubMed Web of Science ®Google Scholar
• Longtin, A. (1993). Stochastic resonance in neuron models. Journal of Statistical Physics, 70, 309–327. doi:10.1007/BF01053970
   Web of Science ®Google Scholar
• Löscher, W., Schmidt, D. (1988). Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy res., 2(3), 145–181. doi:10.1016/0920-1211(88)90054-X
   PubMed Web of Science ®Google Scholar
• Loughney, K., Kreber, R., & Ganetzky, B. (1989). Molecular analysis of the para locus, a sodium channel gene in Drosophila. Cell, 58, 1143–1154. doi:10.1016/0092-8674(89)90512-6
   PubMed Web of Science ®Google Scholar
• Luttjohann, A., Fabene, P., & van Luijtelaar, G. (2009). A revised Racine’s scale for PTZ-induced seizures in rats. Physiology & Behavior, 98, 579–586. doi:10.1016/j.physbeh.2009.09.005
   PubMed Web of Science ®Google Scholar
• Marley, R., & Baines, R. (2011). Increased persistent Na + current contributes to seizure in the slamdance bang-sensitive Drosophila mutant. Journal of Neurophysiology, 106, 18–29. doi:10.1152/jn.00808.2010
   PubMed Web of Science ®Google Scholar
• Melom, J., & Littleton, J. (2013). Mutation of a NCKX eliminates glial microdomain calcium oscillations and enhances seizure susceptibility. Journal of Neuroscience, 33, 1169–1178. doi:10.1523/JNEUROSCI.3920-12.2013
   PubMed Web of Science ®Google Scholar
• Melzig, J., Buchner, S., Wiebel, F., Wolf, R., Buchner, E., Burg, M., & Pak, W. (1996). Genetic depletion of histamine from the nervous system of Drosophila eliminates specific visual and mechanosensory behavior. Journal of Comparative Physiology A, 176, 763–773.
   Google Scholar
• Miller, A. (1950). The internal anatomy and histology of the imago of Drosophila melanogaster. In M. Demerec (Ed.), Biology of drosophila (pp. 420–524). Plainview, NY: Cold Spring Harbor Press.
   Google Scholar
• Miller, T. (1985). Structure and physiology of the circulatory system. In G. Kerkut, & L. Gilbert (Eds.), Comprehensive insect physiology, biochemistry and pharmacology integument, respiration and circulation (1 ed., Vol. 3, pp. 290–349). Oxford, UK: Pergamon Press.
   Google Scholar
• Mu, L., Bacon, J., Ito, K., & Strausfeld, N. (2014). Responses of Drosophila giant descending neurons to visual and mechanical stimuli. Journal of Experimental Biology, 217, 2121–2129. doi:10.1242/jeb.099135
   PubMed Web of Science ®Google Scholar
• Noachtar, S., & Peters, A. (2009). Semiology of epileptic seizures: A critical review. Epilepsy & Behavior, 15, 2–9. doi:10.1016/j.yebeh.2009.02.029
   PubMed Web of Science ®Google Scholar
• Palladino, M., Bower, J., Kreber, R., & Ganetzky, B. (2003). Neural dysfunction and neurodegeneration in Drosophila Na+/K + ATPase alpha subunit mutants. Journal of Neuroscience, 23, 1276–1286. doi:10.1523/JNEUROSCI.23-04-01276.2003
   PubMed Web of Science ®Google Scholar
• Parker, L., Padilla, M., Du, Y., Dong, K., & Tanouye, M. (2011). Drosophila as a model for epilepsy: Bss is a gain-of-function mutation in the para sodium channel gene that leads to seizures. Genetics, 187, 523–534. doi:10.1534/genetics.110.123299
   PubMed Web of Science ®Google Scholar
• Pavlidis, P., & Tanouye, M. (1995). Seizures and failures in the giant fiber pathway of Drosophila bang-sensitive paralytic mutants. Journal of Neuroscience, 15, 5810–5819. doi:10.1523/JNEUROSCI.15-08-05810.1995
   PubMed Web of Science ®Google Scholar
• Phelan, P., Nakagawa, M., Wilkin, M., Moffat, K., O’Kane, C., Davies, J., & Bacon, J. (1996). Mutations in shaking-B prevent electrical synapse formation in the Drosophila giant fiber system. Journal of Neuroscience, 16, 1101–1113. doi:10.1523/JNEUROSCI.16-03-01101.1996
   PubMed Web of Science ®Google Scholar
• Phelan, P., Stebbings, L., Baines, R., Bacon, J., Davies, J., & Ford, C. (1998). Drosophila Shaking-B protein forms gap junction s in paired Xenopus oocytes. Nature, 391, 181–184. doi:10.1038/34426
   PubMed Web of Science ®Google Scholar
• Phillis, R.B., Wotus, C., Whittaker, A., Gramates, L., Seppala, D., Farahanchi, F., … Murphey, R. (1993). Isolation of mutations affecting neural circuitry required for grooming behavior in Drosophila. Genetics, 133, 581–593.
   PubMed Web of Science ®Google Scholar
• Racine, R. (1972). Modification of seizure activity by electrical stimulation: II Motor seizure. Electroencephalography and Clinical Neurophysiology, 32, 281–294. doi:10.1016/0013-4694(72)90177-0
   PubMedGoogle Scholar
• Roeder, K. (1935). An experimental analysis of the sexual behavior of the praying mantis (Mantis religiosa L.). The Biological Bulletin, 69, 203–220. doi:10.2307/1537420
   Google Scholar
• Royden, C., Pirrotta, V., & Jan, L. (1987). The tko locus, site of a behavioral mutation in D. melanogaster, codes for a protein homologous to prokaryotic ribosomal protein S12. Cell, 51, 165–173. doi:10.1016/0092-8674(87)90144-9
   PubMed Web of Science ®Google Scholar
• Ryglewski, S., & Duch, C. (2009). Shaker and Shal mediate transient calcium-independent potassium current in a Drosophila flight motor neuron. Journal of Neurophsiology, 102, 3673–3688. doi:10.1152/jn.00693.2009
   PubMed Web of Science ®Google Scholar
• Ryglewski, S., Kilo, L., & Duch, C. (2014). Sequential acquisition of cacophony calcium currents, sodium channels, and voltage-dependent potassium currents affects spike shape and dendrite growth durin postembryonic maturation of an identified Drosophila motoneuron. The European journal of Neuroscience, 39, 1572–1585. doi:10.1111/ejn.12517
   PubMed Web of Science ®Google Scholar
• Ryglewski, S., Lance, K., Levine, R., & Duch, C. (2012). Cav2 channels mediate low and high voltage-activated calcium currents in Drosophila motoneuron. Journal of Physiology, 590, 809–825. doi:10.1113/jphysiol.2011.222836
   PubMed Web of Science ®Google Scholar
• Sadaf, S., Reddy, O., Sane, S., & Hasan, G. (2015). Neural control of wing coordination in flies. Current Biology, 25, 80–86. doi:10.1016/j.cub.2014.10.069
   PubMed Web of Science ®Google Scholar
• Salkoff, L., & Kelly, L. (1978). Temperature-induced seizure and frequency-dependent neuromuscular block in a ts mutant of Drosophila. Nature, 273, 156–158. doi:10.1038/273156a0
   PubMed Web of Science ®Google Scholar
• Salkoff, L., & Wyman, R. (1981). Outward currents in developing Drosophila flight muscle. Science, 212, 461–463. doi:10.1126/science.6259736
   PubMed Web of Science ®Google Scholar
• Seeds, A., Ravbar, P., Chung, P., Hampel, S., Midgley, F., Mensh, B., & Simpson, J. (2014). A suppression heirarchy among competing motor programs drives sequential grooming in Drosophila. eLife, 3, e02951. doi:10.7554/eLife.02951
   PubMed Web of Science ®Google Scholar
• Siddiqi, O., & Benzer, S. (1976). Neurophysiological defects in temperature sensitive paralytic mtuants of Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America, 73, 3253–3257. doi:10.1073/pnas.73.9.3253
   PubMed Web of Science ®Google Scholar
• Song, J., & Tanouye, M. (2006). Seizure suppression by shakB2, a gap junction mutation in Drosophila. Journal of Neurophysiology, 95, 627–635. doi:10.1152/jn.01059.2004
   PubMed Web of Science ®Google Scholar
• Stilwell, G., Saraswati, S., Littleton, J., & Chouinard, S. (2006). Development of a Drosophila seizure model for in vivo high-throughput drug screening. European Journal of Neuroscience, 24, 2211–2222. doi:10.1111/j.1460-9568.2006.05075.x
   PubMed Web of Science ®Google Scholar
• Szucs, A. (1998). Applications of the spike density function in analysis of neuronal firing patterns. Journal of Neuroscience Methods, 81, 159–167. doi:10.1016/S0165-0270(98)00033-8
   PubMed Web of Science ®Google Scholar
• Takeuchi, A., & Takeuchi, N. (1969). A study of the action of picrotoxin on the inhibitory neuromuscular junction of the crayfish. The Journal of Physiology, 205, 377–391. doi:10.1113/jphysiol.1969.sp008972
   PubMed Web of Science ®Google Scholar
• Tanouye, M., & Wyman, R. (1980). Motor outputs of giant nerve fiber in Drosophila. Journal of Neurophysiology, 44, 405–421. doi:10.1152/jn.1980.44.2.405
   PubMed Web of Science ®Google Scholar
• Thomas, J., & Wyman, R. (1984). Mutations altering synaptic connectivity between identified neurons in Drosophila. Journal of Neuroscience, 4, 530–538. doi:10.1523/JNEUROSCI.04-02-00530.1984
   PubMed Web of Science ®Google Scholar
• Titus, S.A., Warmke, J.W., & Ganetzky, B. (1997). The Drosophila erg K + channel polypeptide is encoded by the seizure locus. Journal of Neuroscience, 17, 875–881. doi:10.1523/JNEUROSCI.17-03-00875
   PubMed Web of Science ®Google Scholar
• Trimarchi, J., & Schneiderman, A. (1995). Flight initiations in Drosophila melanogaster are mediated by several distinct motor patterns. Journal of Comparative Physiology A, 3, 355–364.
   Google Scholar
• Trotta, N., Rodesch, C., Fergestad, T., & Broadie, K. (2004). Cellular bases of activity-dependent paralysis in Drosophila stress-sensitive mutants. Journal of Neurobiology, 60, 328–347. doi:10.1002/neu.20017
   PubMed Web of Science ®Google Scholar
• von Reyn, C.R., Breads, P., Peek, M.Y., Zheng, G.Z., Williamson, W.R., Yee, A.L., … Card, G.M. (2014). A spike-timing mechanism for action selection. Nature Neuroscience, 17, 962–970. doi:10.1038/nn.3741
   PubMed Web of Science ®Google Scholar
• Wang, C.T., Zhang, H.G., Rocheleau, T.A., Ffrench-Constant, R.H., & Jackson, M.B. (1999). Cation permeability and cation-anion interactions in a mutant GABA-gated chloride channel from Drosophila. Biophysical Journal, 77, 691–700. doi:10.1016/S0006-3495(99)76924-9
   PubMed Web of Science ®Google Scholar
• Werner, G., & Mountcastle, V. (1963). The variability of central neural activity in a sensory system, and its implications for the central reflection of sensory events. Journal of Neurophysiology, 26, 958–977. doi:10.1152/jn.1963.26.6.958
   PubMed Web of Science ®Google Scholar
• Williamson, R. (1982). Lithium stops hereditary shuddering in Drosophila melanogaster. Psychopharmacology, 76, 265–268. doi:10.1007/BF00432558
   PubMed Web of Science ®Google Scholar
• Wyman, R. (1965). Probabilistic characterization of simultaneous nerve impulse sequences controlling dipteran flight. Biophysical Journal, 5, 447–471. doi:10.1016/S0006-3495(65)86729-7
   PubMed Web of Science ®Google Scholar
• Yellman, C., Tao, H., He, B., & Hirsh, J. (1997). Conserved and sexually dimorphic behavioral responses to biogenic amines in decapitated Drosophila. Proceedings of the National Academy of Sciences of the United States of America, 94, 4131–4136. doi:10.1073/pnas.94.8.4131
   PubMed Web of Science ®Google Scholar
• Zhang, H.G., Ffrench-Constant, R.H., & Jackson, M.B. (1994). A unique amino acid of the Drosophila GABA receptor with influence on drug sensitivity by two mechanisms. Journal of Physiology, 479, 65–75. doi:10.1113/jphysiol.1994.sp020278
   PubMed Web of Science ®Google Scholar
• Zhang, Y., Roote, J., Brogna, S., Davis, A., Barbash, D., Nash, D., & Ashburner, M. (1999). stress sensitive B encodes an adenine nucleotide translocase in Drosophila melanogaster. Genetics, 153, 891–903.
   PubMed Web of Science ®Google Scholar