372
Views
11
CrossRef citations to date
0
Altmetric
Review Article

Stories of spinster with various faces: from courtship rejection to tumor metastasis rejection

Pages 90-95 | Received 04 Oct 2018, Accepted 11 Feb 2019, Published online: 02 Apr 2019

References

  • Bradley, M., Dasgupta, S., Jiang, X., Zhao, X., Zhu, G., He, Q., … Wang, G. (2014). Critical role of Spns2, a sphingosine-1-phosphate transporter, in lung cancer cell survival and migration. PLoS One, 9, e110119. doi:10.1371/journal.pone.0110119
  • Celia-Terrassa, T., & Kang, Y. (2017). Mouse genomic screen reveals novel host regulator of metastasis. Genome Biology, 18, 31. doi:10.1186/s13059-017-1170-x
  • Chen, J., Ingham, N., Kelly, J., Jadeja, S., Goulding, D., Pass, J., … Jackson, I.J. (2014). Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss. PLOS Genetics, 10, e1004688. doi:10.1371/journal.pgen.1004688
  • Dermaut, B., Norga, K.K., Kania, A., Verstreken, P., Pan, H., Zhou, Y., … Bellen, H.J. (2005). Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer. The Journal of Cell Biology, 170, 127–139. doi:10.1083/jcb.200412001
  • Fang, C., Bian, G., Ren, P., Xiang, J., Song, J., Yu, C., … Liu, F. (2018). S1P transporter SPNS2 regulates proper postnatal retinal morphogenesis. The FASEB Journal, 32, 3597–3613. doi:10.1096/fj.201701116R
  • Fukuhara, S., Simmons, S., Kawamura, S., Inoue, A., Orba, Y., Tokudome, T., … Ishida, J. (2012). The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice. The Journal of Clinical Investigation, 122, 1416–1426. doi:10.1172/JCI60746
  • Han, M., Chang, H., Zhang, P., Chen, T., Zhao, Y., Zhang, Y., … Xu, P. (2013). C13C4.5/Spinster, an evolutionarily conserved protein that regulates fertility in C. elegans through a lysosome-mediated lipid metabolism process. Protein & Cell, 4, 364–372. doi:10.1007/s13238-013-3015-z
  • Hebbar, S., Khandelwal, A., Jayashree, R., Hindle, S.J., Chiang, Y.N., Yew, J.Y., … Schwudke, D. (2017). Lipid metabolic perturbation is an early-onset phenotype in adult spinster mutants: A Drosophila model for lysosomal storage disorders. Molecular Biology of the Cell, 28, 3728–3740. doi:10.1091/mbc.e16-09-0674
  • Herr, D.R., Fyrst, H., Creason, M.B., Phan, V.H., Saba, J.D., & Harris, G.L. (2004). Characterization of the Drosophila sphingosine kinases and requirement for Sk2 in normal reproductive function. Journal of Biological Chemistry, 279, 12685–12694. doi:10.1074/jbc.M310647200
  • Hindle, S., Hebbar, S., & Sweeney, S.T. (2011). Invertebrate models of lysosomal storage disease: What have we learned so far? Invertebrate Neuroscience, 11, 59–71. doi:10.1007/s10158-011-0125-2
  • Hisano, Y., Kobayashi, N., Yamaguchi, A., & Nishi, T. (2012). Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells. PLoS One, 7, e38941. doi:10.1371/journal.pone.0038941
  • Johnson, A.E., Shu, H., Hauswirth, A.G., Tong, A., & Davis, G.W. (2015). VCP-dependent muscle degeneration is linked to defects in a dynamic tubular lysosomal network in vivo. Elife, e07366. doi: 10.7554/eLife.07366.
  • Kawahara, A., Nishi, T., Hisano, Y., Fukui, H., Yamaguchi, A., & Mochizuki, N. (2009). The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors. Science, 323, 524–527. doi:10.1126/science.1167449
  • Kishi, S., Bayliss, P.E., Uchiyama, J., Koshimizu, E., Qi, J., Nanjappa, P., … Amsterdam, A. (2008). The identification of zebrafish mutants showing alterations in senescence-associated biomarkers. PLOS Genetics, 4, e1000152. doi:10.1371/journal.pgen.1000152
  • Kraut, R. (2011). Roles of sphingolipids in Drosophila development and disease. Journal of Neurochemistry, 116, 764–778. doi:10.1111/j.1471-4159.2010.07022.x
  • Mendoza, A., Breart, B., Ramos-Perez, W.D., Pitt, L.A., Gobert, M., Sunkara, M., … Schwab, S.R. (2012). The transporter Spns2 is required for secretion of lymph but not plasma sphingosine-1-phosphate. Cell Reports, 2, 1104–1110. doi:10.1016/j.celrep.2012.09.021
  • Milton, V.J., Jarrett, H.E., Gowers, K., Chalak, S., Briggs, L., Robinson, I.M., & Sweeney, S.T. (2011). Oxidative stress induces overgrowth of the Drosophila neuromuscular junction. Proceedings of the National Academy of Sciences of the United States of America, 108, 17521–17526. doi:10.1073/pnas.1014511108
  • Nagahashi, M., Kim, E.Y., Yamada, A., Ramachandran, S., Allegood, J.C., Hait, N.C., … Spiegel, S. (2013). Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network. The FASEB Journal, 27, 1001–1011. doi:10.1096/fj.12-219618
  • Nakano, Y., Fujitani, K., Kurihara, J., Ragan, J., Usui-Aoki, K., Shimoda, L., … Sano, Y. (2001). Mutations in the novel membrane protein spinster interfere with programmed cell death and cause neural degeneration in Drosophila melanogaster. Molecular and Cellular Biology, 21, 3775–3788. doi:10.1128/MCB.21.11.3775-3788.2001
  • Nijnik, A., Clare, S., Hale, C., Chen, J., Raisen, C., Mottram, L., … Adissu, H. (2012). The role of sphingosine-1-phosphate transporter Spns2 in immune system function. Journal of Immunology, 189, 102–111. doi:10.4049/jimmunol.1200282
  • Nishi, T., Kobayashi, N., Hisano, Y., Kawahara, A., & Yamaguchi, A. (2014). Molecular and physiological functions of sphingosine 1-phosphate transporters. Biochimica et Biophysica Acta, 1841, 759–765. doi:10.1016/j.bbalip.2013.07.012
  • Osborne, N., Brand-Arzamendi, K., Ober, E.A., Jin, S.W., Verkade, H., Holtzman, N.G., … Stainier, D.Y. (2008). The spinster homolog, two of hearts, is required for sphingosine 1-phosphate signaling in zebrafish. Current Biology, 18, 1882–1888. doi:10.1016/j.cub.2008.10.061
  • Perland, E., & Fredriksson, R. (2017). Classification systems of secondary active transporters. Trends in Pharmacological Sciences, 38, 305–315. doi:10.1016/j.tips.2016.11.008
  • Perland, E., Bagchi, S., Klaesson, A., & Fredriksson, R. (2017). Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: Evolutionary conservation, predicted structure and neuronal co-expression. Open Biology, 7. pii: 170142. doi:10.1098/rsob.170142
  • Platt, F.M. (2014). Sphingolipid lysosomal storage disorders. Nature, 510, 68–75. doi:10.1038/nature13476
  • Rong, Y., McPhee, C.K., Deng, S., Huang, L., Chen, L., Liu, M., … Lenardo, M.J. (2011). Spinster is required for autophagic lysosome reformation and mTOR reactivation following starvation. Proceedings of the National Academy of Sciences of the United States of America, 108, 7826–7831. doi:10.1073/pnas.1013800108
  • Saftig, P., & Klumperman, J. (2009). Lysosome biogenesis and lysosomal membrane proteins: Trafficking meets function. Nature Reviews Molecular Cell Biology, 10, 623–635. doi:10.1038/nrm2745
  • Sakurai, A., Koganezawa, M., Yasunaga, K., Emoto, K., & Yamamoto, D. (2013). Select interneuron clusters determine female sexual receptivity in Drosophila. Nature Communications, 4, 1825. doi:10.1038/ncomms2837
  • Sakurai, A., Nakano, Y., Koganezawa, M., & Yamamoto, D. (2010). Phenotypic interactions of spinster with the genes encoding proteins for cell death control in Drosophila melanogaster. Archives of Insect Biochemistry and Physiology, 73, 119–127. doi:10.1002/arch.20345
  • Sasaki, T., Lian, S., Khan, A., Llop, J.R., Samuelson, A.V., Chen, W., … Kishi, S. (2017). Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase. Autophagy, 13, 386–403. doi:10.1080/15548627.2016.1256934
  • Sasaki, T., Lian, S., Qi, J., Bayliss, P.E., Carr, C.E., Johnson, J.L., … Gill, M. (2014). Aberrant autolysosomal regulation is linked to the induction of embryonic senescence: Differential roles of Beclin 1 and p53 in vertebrate Spns1 deficiency. PLOS Genetics, 10, e1004409. doi:10.1371/journal.pgen.1004409
  • Suzuki, K., Juni, N., & Yamamoto, D. (1997). Enhanced mate refusal in female Drosophila induced by a mutation in the spinster locus. Applied Entomology and Zoology, 32, 235–243. doi:10.1303/aez.32.235
  • Sweeney, S.T., & Davis, G.W. (2002). Unrestricted synaptic growth in spinster-a late endosomal protein implicated in TGF-beta-mediated synaptic growth regulation. Neuron, 36, 403–416. doi:10.1016/S0896-6273(02)01014-0
  • Usui-Aoki, K., Nakano, Y., & Yamamoto, D. (2002). Pathology of the adult central nervous system induced by genetic inhibition of programmed cell death in Drosophila pupae. Archives of Insect Biochemistry and Physiology, 49, 94–101. doi:10.1002/arch.10011
  • van der Weyden, L., Arends, M.J., Campbell, A.D., Bald, T., Wardle-Jones, H., Griggs, N., … Karp, N.A. (2017). Genome-wide in vivo screen identifies novel host regulators of metastatic colonization. Nature, 541, 233–236. doi:10.1038/nature20792
  • Venkatesh, B., Lee, A.P., Ravi, V., Maurya, A.K., Lian, M.M., Swann, J.B., … Kasahara, M. (2014). Elephant shark genome provides unique insights into gnathostome evolution. Nature, 505, 174–179. doi:10.1038/nature12826
  • Yamamoto, D., & Nakano, Y. (1999). Sexual behavior mutants revisited: Molecular and cellular basis of Drosophila mating. Cellular and Molecular Life Sciences: CMLS, 56, 634–646. doi:10.1007/s000180050458
  • Yanagisawa, H., Ishii, T., Endo, K., Kawakami, E., Nagao, K., Miyashita, T., … Eto, Y. (2017). l-Leucine and SPNS1 coordinately ameliorate dysfunction of autophagy in mouse and human Niemann–Pick type C disease. Scientific Report, 7, 15944. doi:10.1038/s41598-017-15305-9
  • Yanagisawa, H., Miyashita, T., Nakano, Y., & Yamamoto, D. (2003). HSpin1, a transmembrane protein interacting with Bcl-2/Bcl-xL, induces a caspase-independent autophagic cell death. Cell Death and Differentiation, 10, 798–807. doi:10.1038/sj.cdd.4401246
  • Yonamine, I., Bamba, T., Nirala, N.K., Jesmin, N., Kosakowska-Cholody, T., Nagashima, K., … Acharya, U. (2011). Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors. The Journal of Cell Biology, 192, 557–567. doi:10.1083/jcb.201004098
  • Young, R.M., Marty, S., Nakano, Y., Wang, H., Yamamoto, D., Lin, S., & Allende, M.L. (2002). Zebrafish yolk-specific not really started (nrs) gene is a vertebrate homolog of the Drosophila spinster gene and is essential for embryogenesis. Developmental Dynamics, 223, 298–305. doi:10.1002/dvdy.10060
  • Yu, L., McPhee, C.K., Zheng, L., Mardones, G.A., Rong, Y., Peng, J., … Wan, F. (2010). Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature, 465, 942–946. doi:10.1038/nature09076
  • Yuva-Aydemir, Y., Bauke, A.C., & Klambt, C. (2011). Spinster controls Dpp signaling during glial migration in the Drosophila eye. The Journal of Neuroscience, 31, 7005–7015. doi:10.1523/JNEUROSCI.0459-11.2011
  • Zhu, X., Ren, K., Zeng, Y.Z., Zheng, Z., & Yi, G.H. (2018). Biological function of SPNS2: From zebrafish to human. Molecular Immunology, 103, 55–62. doi:10.1016/j.molimm.2018.08.025

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.