- AUDIBERT, F. M., and LISE, L. D., 1993, Adjuvants: current status, clinical perspectives and future prospects. Immunology Today, 14, 281-284.
- CLELAND, J. L., BARRON, L., BERMAN, P. W., DAUGHERTY, A., GREGORY, T., LIM, A., VENNARI, J., WRIN, T., and POWELL, M. F., 1996, Development of a single-shot subunit vaccine for HIV-1, 2. Defining optimal autoboost characteristics to maximize the humoral immune response. Journal of Pharmaceutical Sciences, 85, 1346-1349.
- CRUZ, T., CASPAR, R., DONATO, A., and LOPES, C., 1997, Interaction between polyalkylycyanoacrylate nanoparticles and peritoneal macrophages: MTT metabolism, NBT reduction, and NO production. Pharmaceutical Research, 14, 73-79.
- DESAI, M. P., HILFINGER, J. M., AMIDON, G. L., LEVY, R. J., and LABHASTETWAR, V., 2000, Immune response with biodegradable nanospheres and alum: studies in rabbits using staphylococcal enterotoxin B-toxoid. Journal of Microencapsulation, 17, 215-225.
- ELDRIDGE, J. H., GILLEY, R. M., STAAS, J. K., MOLDOVEANAU, Z., MEULBROEK, J. A., and TICE, T. R., 1989, Biodegradable microspheres: vaccine delivery system for oral immunization. Current Topics in Microbiology and Immunology, 146, 59-66.
- ELDRIDGE, J. H., STAAS, J. K., CHEN, D., MARX, P. A., TICE, T. R., and GILLEY, R. M., 1993, New advances in vaccine delivery systems. Seminars in Hematology, 30, 16-24.
- ESPARZA, I., and KISSEL, T., 1992, Parameters affecting the immunogenicity of microencapsulated tetanus toxoid. Vaccine, 10, 714-720.
- GUPTA, R. K., 1998, Aluminium compounds as vaccine adjuvants. Advanced Drug Delivery Review, 32, 155-172.
- GUPTA, R. K., and SIBER, G. R., 1995, Adjuvants for human vaccines--current status, problems and future prospects. Vaccine, 13, 1263-1276.
- GUPTA, R. K., CHANG, A.-C., GRIFFIN, P., RIVERA, R., and SIBER, G. R., 1996a, In vivo distribution of radioactivity in mice after injection of biodegradable polymer microspheres containing 14C-labeled tetanus toxoid. Vaccine, 14, 1412-1416.
- GUPTA, R. K., GRIFFIN, P., JR., CHANG, A. C., RIVERA, R., ANDERSON, R., ROST, B., CECCHINI, D., NICHOLSON, M., and SIBER, G. R., 1996b, The role of adjuvants and delivery systems in modulation of immune response to vaccines. Advances in Experimental Medicine and Biology, 397, 105-113.
- LECLERC, C., and VOGEL, F. R., 1986, Synthetic immunomodulators and synthetic vaccines. Critical Reviews in Therapeutics and Drug Carrier Systems, 2, 353-406.
- MARX, P. A., COMPANS, R. W., GETTIE, A., STAAS, J. K., GILLEY, R. M., MULLIGAN, M. J., YAMISCHIKOV, G. V., CHEN, D., and ELDRIDGE, J. H., 1993, Protection against vaginal SIV transmission with microencapsulated vaccine. Science, 260, 1323-1327.
- O'HAGAN, D. T., JEFFERY, H., ROBERTS, M. J., McGEE, J. P., and DAVIS, S. S., 1991, Controlled release microparticles for vaccine development. Vaccine, 9, 768-771.
- O'HAGAN, D. T., OTT, G. S., and VAN NEST, G., 1997, Recent advances in vaccine adjuvants: the development of MF59 emulsion and polymeric microparticles. Molecular Medicine Today, 3, 69-75.
- RAGHUVANSHI, R., 1998, Formulation and evaluation of biodegradable microspheres for controlled release of tetanus toxoid. National Institute of Immunology, Javaharlal University, PhD. thesis, New Delhi, India.
- RAGHUVANSHI, R. S., GOYAL, S., SINGH, O., and PANDA, A. K., 1998, Stabilization of dichloromethane-induced protein denaturation during microencapsulation. Pharmaceutical Development and Technology, 3, 269-276.
- SING, M., LI, X. M., McGEE, J. P., ZAMB, T., KO, W., WANG, C. Y., and O'HAGAN, D. T., 1997a, Controlled release microparticles as a single dose hepatitis B vaccine: evaluation of immunogenicity in mice. Vaccine, 15, 475-481.
- SINGH, M., LI, X. M., WANG, H., MCGEE, J. P., ZAMB, T., KOFF, W., WANG, C. Y., and O'HAGAN, D. T., 1997b, Immunogenicity and protection in small-animal models with controlled-release tetanus toxoid microparticles as a single-dose vaccine. Infection and Immunology, 65, 1716-1721.
- SINGH, M., SINGH, O., and TALWAR, G. P., 1995, Biodegradable delivery system for a birth control vaccine: immunogenicity studies in rats and monkeys. Pharmaceutical Research, 12, 1796-1800.
- STEVENS, V. C., 1993, Vaccine delivery systems: potential methods for use in antifertility vaccines. American Journal of Reproductive Immunology, 29, 176-188.
- WHITE, R. G., COONS, A. H., and CONNOLLY, J. M., 1955, Studies on antibody production. III. The alum granoloma. Journal of Experimental Medicine, 102, 73-82.
- ZHAO, Z., and LEONG, K. W., 1996, Controlled delivery of antigens and adjuvants in vaccine development. Journal of Pharmaceutical Sciences, 85, 1261-1270.
Enhanced immune response with a combination of alum and biodegradable nanoparticles containing tetanus toxoid
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