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Journal of Microencapsulation
Micro and Nano Carriers
Volume 19, 2002 - Issue 1
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Research Article

Protein immobilization in crosslinked alginate microparticles

G. Coppi Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G. Campi 183, 41100 Modena, Italy
,
V. Iannuccelli Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G. Campi 183, 41100 Modena, Italy
,
E. Leo Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G. Campi 183, 41100 Modena, Italy
,
M. T. Bernabei Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G. Campi 183, 41100 Modena, Italy
&
R. Cameroni Department of Pharmaceutical Sciences, University of Modena and Reggio Emilia, Via G. Campi 183, 41100 Modena, Italy
Pages 37-44 | Published online: 29 Sep 2008

  • AUNGST, B. J., 1993, Novel formulation strategies for improving oral bioavailability of drugs with poor membrane permeation or presystemic metabolism. Journal of Pharmaceutical Sciences, 82, 979-987.
  • BODMEIER, R., and PAERATAKUL, O., 1989, Spherical agglomerates of-water-insoluble drugs. Journal of Pharmaceutical Sciences, 78, 964-967.
  • COPPI, G., IANNUCCELLI, V., LEO, E., BERNABEI, M. T., and CAMERONI, R., 2001, Chitosanalginate microparticles as protein carrier. Drug Development and Industrial Pharmacy, 27, 386-393.
  • FLORENCE, A. T., and JANI, P. U., 1993, Paniculate delivery: the challenge of the oral route. In Pharmaceutical Paniculate Carriers: Therapeutic Applications, edited by A. Rolland (New York: Marcel Dekker Inc.) pp. 65-107.
  • OMBOTZ, W. R., and WEE, S. F., 1998, Protein release from alginate matrices. Advanced Drug Delivery Reviews, 31, 267-285.
  • HOPWOOD, D., 1970, Use of isoelectric focusing to determine the isoelectric point of bovine serum albumine after treatment with various common fixatives. Histochemical Journal, 3, 201-205.
  • LOWRY, O. H., ROSEBROUGH, N. J., FARR, A. L., and RANDALL, R. J., 1951, Protein measurement with the Polin Phenol Reagent. Journal of Biological Chemistry, 193, 265-275.
  • LUEßEN, H. L., RENTEL, C. O., KOTZÈ, A. F., LEHR, C.-M., DE BOER, A. G., VERHOEF, J. C., and JUNGINGER, H. E., 1997, Mucoadhesive polymers in peroral peptide drug delivery. IV. Polycarbophil and chitosan are potent enhancers of peptide transport across intestinal mucosae in vitro. Journal of Controlled Release, 45, 15-23.
  • MURATA, Y., MAEDA, T., MIYAMOTO, E., and KAWASHIMA, S., 1993, Preparation of chitosanreinforced alginate gel beads-effects of chitosan on gel matrix erosion. International Journal of Pharmaceutics, 96, 139-145.
  • POLK, A., AMSDEN, B., DE YAO, K., PENG, T., and GOOSEN, M. F. A., 1994, Controlled release of albumin from chitosan-alginate microparticles. Journal of Pharmaceutical Sciences, 83, 178-185.
  • ZHOU, X. H., 1994, Overcoming enzymatic and absorption barriers to non-parenterally administered protein and peptide drugs. Journal of Controlled Release, 29, 239-252.
  • ZHOU, X. H., and WAN Po, L. A., 1991a, Peptide and protein drugs. I. Therapeutic applications, absorption and parenteral administration. International Journal of Pharmaceutics, 75, 97-115.
  • ZHOU, X. H., and WAN Po, L. A., 1991b, Peptide and protein drugs: II. Non-parenteral routes of delivery. International Journal of Pharmaceutics, 75, 117-130.

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