Improved bioavailability of orally delivered insulin using Eudragit-L30D coated PLGA microparticles

References

• Agarwal V, Khan MA. Current status of the oral delivery of insulin. Pharm Technol 2001; 10: 76–90
   Google Scholar
• Aguiar MM, Rodrigues JM, Silva Cunha A. Encapsulation of insulin-cyclodextrin complex in PLGA microspheres: A new approach for prolonged pulmonary insulin delivery. J Microencapsulation 2004; 21: 553–564
   PubMed Web of Science ®Google Scholar
• Arbit E. The physiological rationale for oral insulin administration. Diabetes Technol Ther 2004; 6: 510–517
   PubMedGoogle Scholar
• Brange J. The new era of biotech insulin analogues. Diabetologia 1997; 2: S48–S53
   Google Scholar
• Carino GP, Mathiowitz E. Oral insulin delivery. Adv Drug Deliv Rev 1999; 35: 249–257
   PubMed Web of Science ®Google Scholar
• Cilek A, Celebi N, Tirnaksiz F, Tay A. A lecithin-based microemulsion of rh-insulin with aprotinin for oral administration: Investigation of hypoglycemic effects in non-diabetic and STZ-induced diabetic rats. Int J Pharm 2005; 298: 176–185
   PubMed Web of Science ®Google Scholar
• Crotts G, Park TG. Preparation of porous and nonporous biodegradable polymeric hollow microspheres. J Control Rel 1995; 35: 91–105
   Web of Science ®Google Scholar
• Cui F, Shi K, Zhang L, Tao A, Kawashima Y. Biodegradable nanoparticles loaded with insulin–phospholipid complex for oral delivery: Preparation, in vitro characterization and in vivo evaluation. J Control Rel 2006; 114: 242–250
   PubMed Web of Science ®Google Scholar
• Deutel B, Greindl M, Thaurer M, Schnurch AB. Novel insulin thiomer nanoparticles: in vivo evaluation of an oral drug delivery system. Biomicromolecules 2008; 9: 278–85
   PubMed Web of Science ®Google Scholar
• Goel RK, Mahajan MP, Kulkarni SK. Evaluation of anti-hyperglycemic activity of some novel monocyclic beta lactams. J Pharm Pharm Sci 2004; 7: 80–83
   PubMed Web of Science ®Google Scholar
• Goto T, Morishita M, Nishimura K, Nakanishi M, Kato A, Takayama K. Novel mucosal insulin delivery systems based on fusogenic liposomes. Pharm Res 2006; 23: 384–391
   PubMed Web of Science ®Google Scholar
• Hinds KD, Campbell KM, Holland KM, Lewis DH, Piche CA, Schmidt PG. PEGylated insulin in PLGA microparticles in vivo and in vitro analysis. J Control Rel 2005; 104: 447–460
   PubMed Web of Science ®Google Scholar
• Hori M, Onishi H, Machida Y. Evaluation of Eudragit-coated chitosan particles as an oral immune delivery system. Int J Pharm 2005; 297: 223–234
   PubMed Web of Science ®Google Scholar
• Jain D, Panda AK, Majmumdar DK. Eudragit S100 entrapped insulin microparticles for oral delivery. AAPS Pharm SciTech 2005; 6: E100–E107
   PubMed Web of Science ®Google Scholar
• Kanchan V, Panda AK. Interactions of antigen-loaded polylactide particles with macrophages and their correlation with the immune response. Biomaterials 2007; 28: 5344–5357
   PubMed Web of Science ®Google Scholar
• Katare YK, Muthukumaran T, Panda AK. Influence of particle size, antigen load, dose and additional adjuvant on the immune response from antigen loaded PLA microparticle. Int J Pharm 2005; 301: 150–160
   Google Scholar
• Katare YK, Panda AK. Influences of excipients on in vitro release and in vivo performance of tetanus toxoid loaded polymer particles. Eur J Pharm Sci 2006; 28: 179–188
   PubMed Web of Science ®Google Scholar
• Kim BY, Jeong JH, Park K, Kim JD. Bioadhesive interaction and hypoglycemic effect of insulin loaded lectin-microparticle conjugate in oral insulin delivery system. J Control Rel 2005; 102: 525–538
   PubMed Web of Science ®Google Scholar
• Marschutz MK, Caliceti P, Schnurch AB. Design and in vivo evaluation of an oral delivery system for insulin. Pharm Res 2000; 17: 1468–1474
   PubMed Web of Science ®Google Scholar
• Morishita M, Goto T, Nakamura K, Lowman AM, Takayama K, Peppas NA. Novel oral insulin delivery systems based on complexation polymer hydrogels: single and multiple administration studies in Type 1 and 2diabetic rats. J Control Rel 2006; 110: 587–594
   PubMed Web of Science ®Google Scholar
• Owens DR. New horizons-alternative routes for insulin therapy. Nature Drug Disc Rev 2002; 1: 529–540
   PubMed Web of Science ®Google Scholar
• Packhaeuser CB, Kissel T. On the design of in situ forming biodegradable parenteral depot systems based on insulin loaded dialkylaminoalkyl-amine-poly(vinyl alcohol)-g-poly (lactide-co-glycolide) nanoparticles. J Control Rel 2007; 123: 131–140
   PubMed Web of Science ®Google Scholar
• Pan Y, Li Y, Zhao H, Cui F. Bioadhesive polysaccharide in protein delivery system: Chitosan nanoparticles improve the intestinal absorption of insulin in vivo. Int J Pharm 2002; 249: 139–147
   PubMed Web of Science ®Google Scholar
• Pardakhty A, Varshosaz J, Rouholamini A. In vitro study of polyoxyethylene alkyl ether niosomes for delivery of insulin. Int J Pharm 2007; 328: 130–141
   PubMed Web of Science ®Google Scholar
• Raghuvanshi RS, Goyal S, Singh O, Panda AK. Stabilization of dichloromethane-induced protein denaturation during microencapsulation. Pharm Dev Technol 1998; 3: 269–276
   PubMedGoogle Scholar
• Raghuvanshi RS, Singh OM, Panda AK. Correlation between in vitro release and in vivo immune response from biodegradable polymer particles entrapping tetanus toxoid. Drug Deliv 2002; 9: 113–120
   PubMed Web of Science ®Google Scholar
• Sajeesh S, Sharma CP. Cyclodextrin-insulin complex encapsulated polymethacrylic acid based nanoparticles for oral insulin delivery. Int J Pharm 2006; 325: 147–154
   PubMed Web of Science ®Google Scholar
• Schwendeman SP. Recent advances in the stabilization of proteins encapsulated in injectable PLGA delivery system. Crit Rev Ther Drug Carrier Syst 2002; 19: 73–98
   PubMed Web of Science ®Google Scholar
• Silva CM, Ribeiro AJ, Ferreira D, Veiga F. Insulin encapsulation in reinforced alginate microparticles prepared by internal gelation. Eur J Pharm Sci 2006; 29: 148–159
   PubMed Web of Science ®Google Scholar
• Sood A, Panchagnula R. Peroral route: an opportunity for protein and peptide drug delivery. Chem Rev 2001; 101: 3275–3303
   PubMed Web of Science ®Google Scholar
• Soriano I, Evora C, Llabres M. Preparation and evaluation of insulin loaded poly (Dl-lactide) microparticles using an experimental design. Int J Pharm 1996; 142: 135–142
   Web of Science ®Google Scholar
• Srikanth M, Rao V, Rao S. Modified assay procedure for the estimation of serum glucose using microwell reader. Indian J Clin Biochem 2004; 19: 34–35
   PubMedGoogle Scholar
• Takenaga M, Yamaguchi Y, Ogawa Y, Kitagawa A, Kawai S, Mizushima Y, Igarashi R, Namae M, Komeda K. Administration of optimum sustained-insulin release PLGA microcapsules to spontaneous diabetes-prone BB/Wor//Tky rats. Drug Deliv 2006; 13: 149–157
   PubMed Web of Science ®Google Scholar
• Toorisaka E, Hashida M, Kamiya N, Ono H, Kokazu Y, Goto M. An enteric coated dry emulsion formulation for oral insulin delivery. J Control Rel 2005; 107: 91–96
   PubMed Web of Science ®Google Scholar
• Van de Weert M, Hennink WE, Jiskoot W. Protein instability in poly (lactic-co-glycolic acid) microparticles. Pharm Res 2000; 17: 1159–1167
   PubMed Web of Science ®Google Scholar
• Wang LY, Gu YH, Su ZG, Ma GH. Preparation and release behavior of chitosan microspheres containing insulin. Int J Pharm 2006; 311: 187–195
   PubMed Web of Science ®Google Scholar
• Zhang N, Ping Q, Huang G, Xu W, Cheng Y, Han X. Lectin-modified solid lipid nanoparticles as carrier for oral administration of insulin. Int J Pharm 2006; 327: 153–159
   PubMed Web of Science ®Google Scholar
• Zhu G, Mallory SR, Schwendeman SP. Stabilization of proteins encapsulated in injectable poly (lactide-co-glycolide). Nature Biotechnol 2000; 18: 52–57
   PubMed Web of Science ®Google Scholar
• Ziv E, Bendayan M. Intestinal absorption of peptides through the enterocytes Microscopy Res Technique 2000; 49: 346–352
   PubMed Web of Science ®Google Scholar