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Original Article

Formulation and evaluation of stomach-specific amoxicillin-loaded carbopol-934P mucoadhesive microspheres for anti-Helicobacter pylori therapy

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Pages 365-376 | Published online: 01 Jun 2009

References

  • Gohel MC, Amin AF. Formulation optimization of controlled release diclofenac sodium microspheres using factorial design. J Contr Rel 1998; 51: 115–22
  • Woo BH, Jiang G, Jo YW, DeLuca PP. Preparation and characterization of a composite PLGA and poly (acryloyl hydroxymethyl starch) microsphere system for protein delivery. Pharm Res 2001; 18: 1600–6
  • Capan Y, Jiang G, Giovagnoli S, DeLuca PP. Preparation and characterization of poly (D,L-lactide-co-glycolide) microsphere for controlled release of human growth hormone. AAPS PharmSciTech. 2003; 4, article 28
  • Vasir JK, Tambwekar K, Garg S. Bioadhesive microspheres as a controlled drug delivery system. Int J Pharm 2003; 255: 13–32
  • Ikeda K, Murata K, Kobayashi M, Noda K. Enhancement of bioavailability of dopamine via nasal route in beagle dogs. Chem Pharm Bull 1992; 40: 2155–8
  • Schaefer MJ, Singh J. Effect of isopropyl myristic acid ester on the physical characteristics and in-vitro release of etoposide from PLGA microspheres. AAPS PharmSciTech. 2000; 1, article 32
  • Govender S, Pillay V, Chetty DJ, Essack SY, Dangor CM, Govender T. Optimisation and characterisation of bioadhesive controlled release tetracycline microspheres. Int J Pharm. 2005; 306: 24–40
  • Patel JK, Patel RP, Amin AF, Patel MM. Formulation and evaluation of mucoadhesive glipizide microspheres. AAPS PharmSciTech 2005; 06: E49–55
  • Lehr CM, Bouwstra JA, Schacht EH, Junginger HE. In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers. Int J Pharm 1992; 78: 43–8
  • Henriksen L, Green KL, Smart JD, Smistad G, Karlsen J. Bioadhesion of hydrated chitosans: an in vitro and in vivo study. Int J Pharm 1996; 145: 231–40
  • Rao SB, Sharma CP. Use of chitosan as biomaterial: studies on its safety and hemostatic potential. J Biomed Mater Res 1997; 34: 21–8
  • Chowdary KPR, Rao YS. Design and in vitro and in vivo evaluation of mucoadhesive microcapsules of glipizide for oral controlled release: a technical note. AAPS PharmSciTech. 2003; 4, article 39
  • Chickering D, Jacob J, Mathiowitz E. Bioadhesive microspheres II. Characterization and evaluation of bioadhesion involving hard, bioerodiable polymers and soft tissue. Reactive Polym 1995; 25: 198–206
  • Chun MK, Cho CS, Choi HK. Mucoadhesive drug carrier based on interpolymer complex of poly(vinyl pyrrolidone) and poly(acrylic acid) prepared by template polymerization. J Contr Rel 2002; 17: 327–34
  • Chun M-K, Cho C-S, Choi H-K. Mucoadhesive microspheres prepared by interpolymer complexation and solvent diffusion method. Int J Pharm 2005; 288: 295–303
  • Blanco-Fuente H, Anguiamo-Igea S, Otero-Espinar FJ, Blanco-M’endez J. In vitro bioadhesion of carbopol hydrogel. Int J Pharm 2004; 276: 51–8
  • Liu Z, Lu W, Qian L, Zhang X, Zeng P, Pan J. In vitro and in vivo studies on mucoadhesive microspheres of amoxicillin. J Contr Rel 2005; 102: 135–44
  • Warren JR, Marshall B. Unified curved bacilli on gastric epithelium in active chronic gastritis. Lancet 1983; 321: 1273–5
  • Magraud F, Lamouliatte H. Helicobacter pylori and duodenal ulcers. Dig Dis Sci 1992; 37: 769–72
  • Forman D, Webb P, Personnet J. H. pylori and gastric cancer. Lancet 1994; 343: 243–4
  • Forman D, Newell F, Fullerton J, Yarnell A, Stacey N, Wald S. Association between infection with Helicobacter pylori and risk of gastric cancer: evidence from a prospective investigation. Br Med J 1991; 302: 302–5
  • Blaser M. Ecology of Helicobacter pylori in the human stomach. J Clin Invest 1997; 100: 759–62
  • Malfertheiner P, Megraud C, O’Morain A, Hungin R, Jones A, Axon D, et al. European Helicobacter Pylori Study Group (EHPSG). Current concepts in the management of Helicobacter pylori infection–the Maastricht 2-2000 Consensus Report. Aliment Pharmacol Ther 2002; 16: 167–80
  • Gisbert J, Pajares J. Helicobacter pylori therapy: first-line options and rescue regimen. Dig Dis 2001; 19: 134–43
  • Jenks P, Edwards D. Metronidazole resistance in Helicobacter pylori. Int J Antimicrob Agents 2002; 19: 1–7
  • Osato M, Reddy S, Reddy R, Penland R, Malaty H, Graham D. Pattern of primary resistance of Helicobacter pylori to metronidazole or clarithromycin in the United States. Arch Intern Med 2001; 161: 1217–20
  • Wu H, Shi XD, Wang HT, Liu JX. Resistance of Helicobacter pylori to metronidazole, tetracycline and amoxycillin. J Antimicrob Chemother 2000; 46: 121–3
  • Kwon D, Kim J, Lee M, Yamaoka M, Kato M, Osato F, et al. Isolation and characterization of tetracycline-resistant clinical isolates of Helicobacter pylori. Antimicrob Agents Chemother 2000; 44: 3203–5
  • Buzas GM, Szekely E. Eradication of Helicobacter pylori in peptide ulcer patients. Orv Hetil 1999; 140: 121–4
  • Suleymanlar I, Tuncer M, Tugrul MS, Erttugrul C, Sarikaya M, Fevzi FE, et al. Response to triple treatment with omeprazole, amoxicillin and clarithromycin for Helicobacter pylori infections in continuous ambulatory peritoneal dialysis patients. Adv Perit Dial 1999; 15: 79–81
  • Vakil N, Cutler A. Ten-day triple therapy with ranitidine, bismuthcitrate, amoxicillin and clarithromycin in eradicating Helicobacter pylori. Am J Gastroenterol 1999; 94: 1197–9
  • Kawabami E, Ogata SK, Portorreal AC. Triple therapy with clarithromycin amoxicillin and omeprazole for Helicobacter pylori in eradication in children and adolescents. Arq Gastroenterol 2001; 38: 203–6
  • Lin CK, Hsu PI, Lai KH. One-week quadruple therapy is an effective salvage regiment for Helicobacter pylori infection in patients after failure of standard triple therapy. J Clin Gastroenterol 2002; 34: 547–51
  • Cooreman MP, Krausgrill P, Hengels KJ. Local gastric and serum amoxicillin concentrations after different oral application forms. Antimicrob Agents Chemother 1993; 37: 1506–9
  • Atherton JC, Cockayne A, Balsitis M, Kirk GE, Hawley CJ, Spiller RC. Detection of the intragastric sites at Helicobacter pylori evades treatment with amoxicillin and cimetidine. Gut 1995; 36: 670–4
  • Axon AT. The role of acid inhibition in the treatment of Helicobacter pylori infection. Scand J Gastroenterol 1994; 29: 16–23
  • Giacomo F, Marinano L, Silvana M, Domenico S, Gaetano G. Amoxicillin-loaded polyethylcyanoacrylate nanoparticles: influence PEG coating on the particle size, drug release rate and phagocytic uptake. Biomaterials 2001; 22: 2857–65
  • Hilton AK, Deasy PB. In vitro and in vivo evaluation of an oral sustained-release floating dosage form of amoxicillin trihygrate. Int J Pharm 1992; 86: 79–88
  • Nagahara N, Akiyama Y, Nako M, Tada M, Kitano M, Ogawa Y. Mucoadhesive microspheres containing amoxicillin for clearance of Helicobacter pylori. Antimicrob Agent Chemother 1998; 42: 2492–4
  • Patel JK, Patel MM. Stomach specific anti-Helicobacter Pylori therapy- preparation and evaluation of amoxicillin loaded chitosan mucoadhesive microspheres. Curr Drug Deliv 2007; 4: 41–51
  • Eugene L. Milling. The theory and practice of industrial pharmacy2nd, L Lachman, HA Liberman. Varghese publishing house, Mumbai 1991; 26–7
  • Lehr CM, Bowstra JA, Tukker JJ, Junginger HE. Intestinal transit of bioadhesive microspheres in an in situ loop in the rat. J Contr Rel 1990; 13: 51–62
  • Dokoumetzidis A, Papadopoulou V, Macheras P. Analysis of dissolution data using modified versions of Noyes-Whitney equation and the Weibull function. Pharm Res 2006; 23: 256–61
  • Korsemeyer R, Gurny R, Peppas N. Mechnisums of solute release from porous hydrophilic polymers. Int J Pharm 1983; 15: 25–35
  • Karasulu E, Karasuslu HY, Ertan G, Kirilmaz L, Guneri T. Extended release lipophillic indomethacin microspheres: formulation factors and mathematical equations fitted drug release rates. Eur J Pharm Sci 2003; 19: 99–104
  • Lee JW, Park JH, Robinson JR. Bioadhesive-based dosage forms: the next generation. J Pharm Sci 2000; 89: 850–66
  • Ogwal S, Xide TU. Bioavailability and stability of erythromycin delayed release tablets. Afr Health Sci 2001; 2: 90–6
  • Erach PO, Goddard AF, Barrett DA, Shaw PN, Spiller RC. The stability of amoxicillin, clarithromycin and metronidazole in gastric juice: relevance to the treatment of Helicobacter pylori infection. J Antimicrob Chemother 1997; 39: 5–12
  • Mascher C, Kikuta C. Determination of amoxicillin in human serum and plasma by high-performance liquid chromatography and on-line postcolumn derivatisation. J Chromatogr A 1998; 182: 221–6
  • Chadha R, Kashid N, Jain DV. Kinetic studies of the degradation of an aminopenicillin antibiotic in aqueous solution using heat conduction microcalorimerty. J Pharm Pharmcol 2003; 55: 1495–503

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