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Research Article

Ketoprofen-poly(D,L-lactic-co-glycolic acid) microspheres: influence of manufacturing parameters and type of polymer on the release characteristics

Pages 1-12 | Published online: 29 Sep 2008

References

  • BODMEIER, R., and MCGINITY, R. W., 1987, The preparation and evaluation of drug-containing poly(dl-lactide) microspheres formed by the solvent evaporation method. Pharmaceutical Research, 4, 465–471.
  • BODMEIER, R., and CHEN, H., 1989, Preparation and characterization of microspheres containing the anti-inflammatory agents indomathacin, ibuprofen and ketoprofen. Journal of Controlled Release, 10, 167–175.
  • CONTI, B., PAvANETTo, F., and GENTA, I., 1992, Use of polylactic acid for the preparation of microparticulate drug delivery systems. Journal of Microencapsulation, 9, 153–166.
  • EL-GIBALY, I., SAFWAT, S. M., and AHMED, M. 0., 1996, Microencapsulation of ketoprofen using w/o/w complex emulsion technique Journal of Microencapsulation, 13, 67–97.
  • ERMAK, T. H., DOUGHERTY, E. P. BHAGAT, H. R., KABOK, Z., and PAPE°, J., 1995, Uptake and transport of copolymer biodegradable microspheres by rabbit Peyer's patch M cells. Cell and Tissue Research, 279, 433–436.
  • GUTERRES, S. S., FESSI, H. BARRATT, G., PUISIEUX, F., and DEVISSAGUET, J.-P., 1995, Poly(D,L-lactide) nanocapsules containing non-steroidal anti-inflammatory drugs: gastrointestinal tolerance following intravenous and oral administration. Pharmaceutical Research, 12, 1545–1547.
  • GOTO, S., KAWATA, M., NAKAMURA, M., MAEKAWA, K., and AOYAMA, T., 1986a, Eudragit RS and RL (acrylic resins) microcapsules as pH insensitive and sustained release preparations of ketoprofen. Journal of Microencapsulation, 3, 293–304.
  • GOTO, S., KAWATA, M., NAKAMURA, M., MAEKAWA, K., and AOYAMA, T., 1986b, Eudragit E, L and S (acrylic resins) microcapsules as pH sensitive release preparations of ketoprofen. Journal of Microencapsulation, 3, 305–316.
  • Guiziou, B., ARMSTRONG, D. J., ELLIOTT, P. N. C., FORD, J. L., and ROSTRON, C., 1996, Investigation of in-vitro characteristics of NSAID-loaded polylactic acid microspheres. Journal of Microencapsulation, 13, 701–708.
  • IGNATIUS, A. A., and CLAES, L. E., 1996, In vitro biocompatibility of bioresorbable polymers: poly(L,DL-lactide) and poly(L-lactide-co-glycolide). Biomaterials, 17, 831–839.
  • MAZE, G. I., REINHARDT, R. A., AGARWAL, R. K., DYER, J.ROBINSON, D. H., DuBois, L. M., TUSSING, G. J., and MAZE, C. R., 1995, Response to intracrevicular controlled delivery of 25%0 tetracycline from poly(lactide/glycolide) film strips in SFT patients. Journal of Clinical Periodontology, 22, 860–867.
  • O'DoNNEuu, P. B., and McGiNrry, J. W., 1996, Properties of multiphase microspheres of poly(dl-lactic acid) or poly(dl-lactic-co-glycolic acid) produced by mechanical agitation, sonication or potentiometric dispersion. Journal of Microencapsulation, 13, 667–677.
  • OKADA, H., and Tocuum, H., 1995, Biodegradable microspheres in drug delivery. Critical Reviews in Therapeutic Drug Delivery Systems, 12, 1–99.
  • PARK, T. G., 1995, Degradation of poly(lactic-co-glycolic acid) microspheres: effect of copolymer composition. Biomaterials, 16, 1123–1130.
  • ROLLAND, A., WAGNER, N., CHATELUS, A., SHROOT, B.„ and SCHAEFER, H., 1993, Site-specific drug delivery to pilosebaceous structures using polymeric microspheres. Pharmaceutical Research, 10, 1738–1744.
  • SANCHEZ, A., VILA-JATO, J. L., and ALONSO, M. J., 1993, Development of biodegradable microspheres and nanospheres for the controlled release of cyclosporin A. International Journal of Pharmaceutics, 99, 263–273.
  • SANSDRAP, P., and MoEs, A. J., 1993, Influence of manufacturing parameters on the size characteristics and the release profiles of nifedipine from poly(DL-lactide-co-glycolide) microspheres. International Journal of Pharmaceutics, 98, 157–164.
  • VOLLAND, C., WOLFF, M., and KISSEL, T., 1994, The influence of terminal gamma-sterilization on captopril containing poly(D,L-lactide-co-glycolide) microspheres. Journal of Controlled Release, 31, 293–305.
  • ZHANG, X., WYSS, U. P., PICHORA, D., and GoosEN, M. F., 1994, A mechanistic study of antibiotic release from biodegradable poly(d,l-lactide) cylinders. Journal of Controlled Release, 31, 128–144.

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