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Journal of Medical and Veterinary Mycology Volume 29, 1991 - Issue 1
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Original Article

Phenotypes of Candida albicans sterol mutants deficient in Δ8,7-isomerization or 5-desaturation

O. Shimokawa Department of Microbiology, Faculty of Dentistry, Kyushu University, Fukuoka, 812, Japan
&
H. Nakyama Department of Microbiology, Faculty of Dentistry, Kyushu University, Fukuoka, 812, Japan
Pages 53-56 | Accepted 04 Oct 1990, Published online: 09 Jul 2009

REFERENCES

  • Parks L.W., McLean-Bowen C.A., Taylor F.R., Hough S. Sterols in yeast subcellular fraction. Lipid 1978; 13: 730–735
  • Shimokawa O., Kato Y., Kawano K., Nakayama H. Accumulation of 14α-methylergosta-8, 24(28)-dien-3β, 6α-diol in 14α-demethylation mutants of Candida albicans: genetic evidence for the involvement of 5-desaturase. Biochimica et Biophysica Acta 1989; 1003: 15–19
  • Shimokawa O., Kato Y., Nakayama H. Accumulation of 14-methyl sterols and defective hyphal growth in Candida albicans. Journal of Medical and Veterinary Mycology 1986; 24: 327–336
  • Shimokawa O., Kato Y., Nakayama H. Increased drug sensitivity in Candida albicans cells accumulating 14 methylated sterols. Journal of Medical and Veterinary Mycology 1986; 24: 481–483
  • Shimokawa O., Nakayama H. A Candida albicans mutant conditionally defective in sterol 14α-demethylation. Journal of Medical and Veterinary Mycology 1989; 27: 121–125

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