55
Views
22
CrossRef citations to date
0
Altmetric
Research Article

Nitric oxide and glioma: a target for novel therapy?

&
Pages 213-220 | Published online: 06 Jul 2009

  • Katsuti S, Arnold W, Mittal C, Murad F. Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine. J Cyclic Nucleotide Res 1977; 3:23-35.
  • Murad F, Mittal CK, Arnold WP, Katsuti S, Kimura H. Guanylate cyclase: activation by azide, nitro compounds, nitric oxide, and hydroxyl radical and inhibition by hemoglobin and myoglobin. Adv Cyclic Nucleotide Res 1978; 9:145-58.
  • Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980; 288:373-6.
  • Furchgott RF, Vanhoutte PM. Endothelium derived relaxing and contractor factors. FASEB J 1989; 3:20007-18.
  • Ignarro LJ. Endothelium-derived nitric oxide: actions and properties. FASEB J 1989; 3:31-6.
  • Palmer RMJ, Fertige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing actor. Nature 1987; 327:524.
  • Palmer RMJ, Rees DD, Ashton DS, Moncada S. Larginine is the physiological precursor for the formation of nitric oxide in endothelium dependent relaxation. Biochem Biophys Res Comm 1988; 153:1256.
  • Murphy S, Simmons ML, Agullo L, et al Synthesis of nitric oxide in CNS glial cells. Trends Neurosci 1993; 16:323-8.
  • Faraci FM, Brian JE. Nitric oxide and the cerebral virculation. Stroke 1994; 25:692-703.
  • Änggård E. Nitric oxide: mediator, murderer, and medicine. Lancet 1994; 343:1199-206.
  • Paakkari I, Lindsberg P. Nitric oxide in the central nervous system. Ann Med 1995; 27:369-77.
  • O'Mahony D, Kendall MJ. Nitric oxide in acute ischemie stroke: a target for neuroprotection. J Neural Neurosurg Psychiatry 1999; 67:l-3.
  • Wink DA, Vodovotz Y, Lavai J, Lavai F, Dewhirst MW, Mitchell JB. The multifaceted roles of nitric oxide in cancer. Carcinogenesis 1998; 19:711-21.
  • Chinje EC, Stratford IJ. Role of nitric oxide in growth of solid tumours: a balancing act. Essays in Biochem 1997,32:61-72.
  • Scmidt HHHW, Gagne GD, Nakane M, Pollock JS, Miller MF, Murad F. Mapping of neural nitric oxide synthase in the rat suggests frequent co-localization with NADPH diaphorase but not soluble guanylyl cyclase, and novel paraneural functions for nitrinergic signal transduction. J Histochem Cytochem 1992; 40:1439-56.
  • O'Dell TJ, Huang PL, Dawson TM, et al Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS. Science 1994,265:542-6.
  • Radomski MW, Palmer RMJ, Moncada S. The antiaggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide. Br J Pharmacol 1987; 92:639-46.
  • Shinoda J, Bell HS, Swaroop GR, Yamaguchi S, Holmes MC, Whittle IR. Inhibition of iNOS induction in C, glioma cells by glucocorticoids. Neurooncology 1999; 1:S102.
  • Simmons ML, Murphy S, Cytokines regulate Larginine-dependent cyclic GMP production in rat glial cells. Eur J Neurosci 1993; 5:825-31.
  • Ling-Ling C, Nakamura T, Nakatsu Y, Sakumi K, Hayakawa H. Specific amino acid sequences required for O6-methylguanine-DNA-methyltransferase activity: analysis of three residues at or near the methyl acceptor site. Carcinogenesis 1992; 13:837-43.
  • Zak P, Kliebl K, Laval F. Repair of O6-methylguanine and O4-methylthymine by human and rat O6-methylguanine-DNA-methyltransferase. J Biol Chent 1994; 269:730-3.
  • Granziewica M, Wink DA, Laval F. Nitric oxide inhibits DNA ligase activity Potential mechanisms for NO mediated DNA damage. Carcinogenesis 1996; 17:2501-5.
  • Fenoglio C, Necchi D, Civallero M, Ceroni M, Nano R. Cytochemical demonstration of nitric oxide synthase and 5'nucleotidase in human glioblastoma. Anticancer Res 1997; 17:2507-12.
  • Swaroop GR, Whittle IR. Nitric oxide synthase expression in malignant glioma: A histochemical study. Neurol India 1998,46:23-29.
  • Cobbs CS, Brenman JE, Aldape KD, Bredt DS, Israel MA. Expression of nitric oxide synthase in human central nervous system tumours. Cancer Res 1995; 55:727-30.
  • Bakshi A, Nag TC, Wadhwa S, Mahapatra AK, Sarkar C. The expression of nitric oxide syntheses in human brain tumours and peritumoural areas. J Neural Set 1998; 155:196-203.
  • Ellie E, Loiseau H, Lafond F, Arsaut J, DemotesMainard J. Differential expression of inducible nitric oxide synthase mRNA in human brain tumours. Neuroreport 1995; 7:294-6.
  • Kara E, Takahashi K, Tominaga T, et al. Expression of heme oxgenase and inducible nitric oxide synthase mRNA in human brain tumors. Biochem Biophys Res Commun 1996; 224:153-8.
  • Persichini, Mancino G, Cappelli G, Colizzi V, Lauro GM. Mycobacterium tuberculosis enhances iNOS mRNA expression and HIV replication in human astrocytoma cells. Neuroreport 1997; 8:1897901.
  • Colasanti M, Mollace V, Cundari E, Massoud R, Nistico G, Lauro M. The generation of nitric oxide participates in gIFN-induced MHC class II antigen expression by cultured astrocytoma cells. Int J Immunopharmacol 1993; 15:763-71.
  • Rieger J, Ständer M, Löschmann PA, et al. Synthesis and biological effects of NO in malignant glioma cells: modulation by cytokines including CD95L and TGFb, dexamethasone, and p53 gene transfer. Oncogene 1998; 17:2323-32.
  • Nakao S, Matsukado K, Black KL. Increased brain tumor microvessel permeability after intracarotid bradykinin infusion is mediated by nitric oxide. Cancer Res 1996; 56:4027-31.
  • Bama M, Komatsu T, Reiss CS. Activation of type III 7 nitric oxide synthase in astrocytes following a neurotropic viral infection. Virology 1996; 223:331-43.
  • Simmons ML, Murphy S. Induction of nitric oxide synthase in glial cells. J Neurochem 1992; 59:897-905.
  • Galea E, Feinstein DL, Reis DJ. Induction of calciumindependent nitric oxide synthase activity in primary rat astrocyte cultures. Proc Natl Acad Sd USA 1992; 89:10945-9.
  • Feinstein DL, Galea E, Roberts S, Berquist H, Wang H, Reis DJ. Induction of nitric oxide synthase in rat C6 glioma cells. J Neurochem 1994; 62:315-21.
  • Miller KJ, Gonzalez HA. Serotonin 5-HT2A receptor activation inhibits cytokine-stimulated inducible nitric oxide synthase in C6 glioma cells. Ann NY Acad Sci 1998; 861:169-73.
  • Ding AH, Nathan CF, Stuerth DJ. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J Immunol 1998; 141:2407-12.
  • Busse R, Mülsch A. Induction of nitric oxide synthase by cytokines in vascular smooth muscle cell. FEBS Lett 1990; 275:87-90.
  • Kilbourn RG, Belloni I. Endothelial cell production of nitric oxides in response to interfern in combination with tumor necrosis actor, interleukin-1, or endotoxin. J Narl Cancer Inst 1990; 82:772-6.
  • Geller DA, Nussler AK, DiSilvio M, et al Cytokines, endotoxin and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes. Proc Natl Acad Sci USA 1993; 90:522-6.
  • Galea E, Reddi J, Feinstein DL. Differential suppression of glial nitric oxide synthase induction by structurally related tyrosine kinase inhibitors. Neurosci Lett 1995; 200:195-8.
  • Nicotera P, Bonfoco E, Brune B. Mechanisms for nitric oxide-induced cell death: Involvement of apoptosis. Adv Neuroimmunol 1995; 5:411-20.
  • Dong Z, Staroselsky AH, Qi X, Xie K, Fidler IJ. Inverse correlation between expression of inducible nitric oxide synthase activity and production of metastasis in K-1735 murine melanoma cells. Cancer Res 1994; 54:789-93.
  • Kong L, Dunn GD, Keefer LK, Korthuis RJ. Nitric oxide reduces tumor cell adhesion to isolated rat postcapillary venules. Clin Exp Metastasis 1996; 14:335-43.
  • Murata J, Ricciardi-Castagnoli P, Dessous L'Eglise Mange P, Martin F, Juillerat-Jeanneret L. Microglial cells induce cytotoxic effects toward colon carcinoma cells: measurement of tumor cytotoxicity with a gamma-glutamyl transpeptidase assay. Int J Cancer 1997; 70:169-74.
  • Khan BV, Harrison DG, Olbrych MT, Alexander RW, Medford RM. Nitric oxide regulates vascular cell adhesion molecule 1 gene expression and redox-sensitive transcriptional events in human vascular endothelial cells. Proc Natl Acad Sei USA 1996; 93:9114-19.
  • Chin K, Kurashima Y, Ogura T, Tajiri H, Yoshida S, Esumi H. Induction of vascular endothelial growth factor by nitric oxide in human glioblastoma and hepatocellular carcinoma cells. Oncogens 1997; 15:437-42.
  • Tsurumi Y, Murohara T, Krashinski K, et al. Reciprocal relation between VEGF and NO in the regulation of endothelial integrity. Natl Med 1997; 3:879-86.
  • Tawara Y, Kagaya A, Uchitomi Y, Horiguchi J, Yamawaki S. Lipopolysaccharide regulate both serotonin-and thrombin-induced intracellular calcium mobilization in rat C6 glioma cells: possible involvement of nitric oxide synthase-mediated pathway. J Neurosci Res 1998; 51:517-25.
  • Kelly PA, Thomas CL, Ritchie IM, Arbuthnott GW. Cerebrovascular autoregulation in response to hypertension induced by NG-nitro-L-arginine methyl ester. Neuroscience 1994,59:13-20.
  • Iadecola C, Zhang F, Xu X. SIN-1 reverses attenuation of hypercapnic cerebrovasodilatation by nitric oxide synthase inhibitors. Am J Physiol 1994; 267:R228-35.
  • Swaroop GR, Malcolm GP, Kelly PAT, Ritchie I, Whittle IR. Effects of nitric oxide modulation on tumour blood flow and microvascular permeability in C6 glioma. Neuroreport 1998; 9:2577-81.
  • Whittle IR, Collins F, Kelly PA, Ritchie I, Ironside JW. Nitric oxide synthase is expressed in experimental malignant glioma and influences tumour bloodflow. Acta Neurochir (Wien) 1996; 138:870-5.
  • Malcolm GP, Jodrell DI, MacLellan A, Swaroop GR, Kelly PAT, Whittle IR. Effects of nitric oxide manipulation on the disposition of platinum in an experimental glioma model. Neuroreport 1998; 9:1815.
  • Matsukado K, Inamura T, Nakano S, Fukui M, Bartus RT, Black KL. Enhanced tumor uptake of carboplatin and survival in glioma-bearing rats by intracarotid infusion of bradykinin analog, RMP-7. Neurosurgery 1996; 39:125-34.
  • Koga H, Inamura T, Ikezaki K, Nomura T, Samoto K, Fukui M. Increased delivery of a new cisplatin analogue (254-s) in a rat brain tumor by an intracarotid infusion of bradykinin. Neural Res 1996; 18:2447.
  • Matsukado K, Sugita M, Black KL. Intracarotid low dose bradykinin infusion selectively increases tumor permeability through activation of bradykinin B2 receptors in malignant gliomas. Brain Res 1998; 792:10-15.
  • Black KL, Cloughesy T, Huang SC, et al. Intracarotid infusion of RMP-7, a bradykinin analog, and transport of gallium-68 ethylenediamine tetraacetic acid into human gliomas. J Neurosurg 1997; 86:603-9.
  • Ford J, Osborn C, Barton T, Bleehen NM. A phase I study of intravenous RMP-7 with carboplatin in patients with progression of malignant glioma. Eur J Cancer 1998; 34:1807-11.
  • Earth RF, Yang W, Bartus RT, Moeschberger ML, Goodman JH. Enhanced delivery of boronophenylalanine for neutron capture therapy of brain tumors using the bradykinin analog Cereport (ReceptorMediated Permeabilizer-7). Neurosurgery 1999; 44:351-9.
  • LeMay DR, Kittaka M, Gordon EM, et al Intravenous RMP-7 increases delivery of ganciclovir into rat brain tumors and enhances the effects of herpes simplex virus thymidine kinase gene therapy. Hum Gene Ther 1998; 9:98-995.
  • Rainov NG, Dobberstein KU, Heidecke V, et al Long-term survival in a rodent brain tumor model by bradykinin-enhanced intra-arterial delivery of a therapeutic herpes simplex virus vector. Cancer Gene Ther 1998; 5:158-62.
  • Lee YS, Wurster RD. Potentiation of anti-proliferative effect of nitroprusside by ascorbate in human brain tumor cells. Cancer Lett 1994; 78:19-23.
  • Lee YS, Wurster RD. Mechanisms of potentiation of LY83583-induced growth inhibition by sodium nitroprusside in human brain tumor cells. Cancer Chemother Pharmacol 1995; 36:341-4.
  • Kurimoto M, Endo S, Hiroshima Y, Hamada H, Ogiichi T, Takaku A. Growth inhibition and radiosensitization of cultured glioma cells by nitric oxide generating agents. J Neurooncol 1999; 42:35-44.
  • Swaroop GR, Kelly PAT, Bell H, Yamaguchi S, Shinoda J, Whittle IR. The effects of chronic nitric oxide synthase expression on glioma pathophysiology. Br J Neurosurg 2000; 14:543-8.
  • Yamaguchi S, Shinoda J, Holmes MC, Whittle IR. Is tumorgenecity dependent on glioma expression of iNOS? Studies using antisense knockout of iNOS expression in C6 glioma cell line. Neurooncol 1999; 1:S103.
  • Yamaguchi S, Shinoda J, Bell H, Holmes M, Whittle IR. Tumourgenicity dependence of C6 cells on iNOS; studies using the rodent striatal implantation model. Br J Neurosurg, in press.
  • Juang SH, Xie K, Xu L, et al. Suppression of tumourogenicity and metastsase of human renal carcinoma cell by infection with retroviral vectors harbouring the murine-inducible NOS gene. Hum Gene Ther 1998; 9:845-54.
  • Swaroop GR, Kelly PAT, Holmes MC, Whittle IR. The effects of dexamethasone on vascular permeability, blood flow and iNOS expression in experimental glioma. J Clin Neurasci 2001; 8:35-9.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.