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Original Article

Nebivolol attenuates cerebral vasospasm both by increasing endothelial nitric oxide and by decreasing oxidative stress in an experimental subarachnoid haemorrhage

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Pages 439-445 | Received 08 Dec 2015, Accepted 11 Jan 2017, Published online: 23 Mar 2017

References

  • Aladag MA, Turkoz Y, Sahna E, et al. The attenuation of vasospasm by using a sod mimetic after experimental subarachnoidal haemorrhage in rats. Acta Neurochir (Wien) 2003;145:673–7.
  • Aladag MA, Turkoz Y, Ozcan C, et al. Caffeic acid phenethyl ester (CAPE) attenuates cerebral vasospasm after experimental subarachnoidal haemorrhage by increasing brain nitric oxide levels. Int J Dev Neurosci 2006;24:9–14.
  • Aladag MA, Turkoz Y, Parlakpinar H, et al. Melatonin ameliorates cerebral vasospasm after experimental subarachnoidal haemorrhage correcting imbalance of nitric oxide levels in rats. Neurochem Res 2009;34:1935–44.
  • Ciurea AV, Palade C, Voinescu D, Nica DA. Subarachnoid hemorrhage and cerebral vasospasm: literature review. J Med Life 2013;6:120–5.
  • Dietrich HH, Dacey RG Jr. Molecular keys to the problems of cerebral vasospasm. Neurosurgery 2000;46:517–30.
  • Hänggi D, Steiger HJ. Nitric oxide in subarachnoid haemorrhage and its therapeutics implications. Acta Neurochir (Wien) 2006;148:605–13.
  • Asano T. Oxyhemoglobin as the principal cause of cerebral vasospasm: a holistic view of its actions. Crit Rev Neurosurg 1999;9:303–18.
  • Sercombe R, Dinh YR, Gomis P. Cerebrovascular inflammation following subarachnoid hemorrhage. Jpn J Pharmacol 2002;88:227–49.
  • Hall ED, Wang JA, Bosken JM, Singh IN. Lipid peroxidation in brain or spinal cord mitochondria after injury. J Bioenerg Biomembr 2015; (in press). doi: 10.1007/s10863-015-9600-5
  • Hall ED, Vaishnav RA, Mustafa AG. Antioxidant therapies for traumatic brain injury. Neurotherapeutics 2010;7:51–61.
  • Erdi MF, Guney O, Kiyici A, Esen H. The effects of alpha lipoic acid on cerebral vasospasm following experimental subarachnoid hemorrhage in the rabbit. Turk Neurosurg 2011;21:527–33.
  • Lu H, Zhang DM, Chen HL, et al. N-acetylcysteine suppresses oxidative stress in experimental rats with subarachnoid hemorrhage. J Clin Neurosci 2009;16:684–8.
  • Fathi AR, Bakhtian KD, Pluta RM. The role of nitric oxide donors in treating cerebral vasospasm after subarachnoid hemorrhage. Acta Neurochir Suppl 2011;110:93–7.
  • Pathak A, Mathuriya SN, Khandelwal N, Verma K. Intermittent low dose intrathecal sodium nitroprusside therapy for treatment of symptomatic aneurysmal SAH-induced vasospasm. Br J Neurosurg 2003;7:306–10.
  • Siuta M, Zuckerman SL, Mocco J. Nitric oxide in cerebral vasospasm: theories, measurement, and treatment. Neurol Res Int 2013;2013:972417.
  • Khan MU, Zhao W, Zhao T, et al. Nebivolol: a multifaceted antioxidant and cardioprotectant in hypertensive heart disease. J Cardiovasc Pharmacol 2013;62:445–51.
  • Vanhoutte PM, Gao Y. Beta blockers, nitric oxide, and cardiovascular disease. Curr Opin Pharmacol 2013;13:265–73.
  • Weiss RJ, Saunders E, Greathouse M. Efficacy and tolerability of nebivolol in stage I-II hypertension: a pooled analysis of data from three randomized, placebo-controlled monotherapy trials. Clin Ther 2011;33:1150–61.
  • Hjalmarson A. Cardioprotection with beta-adrenoceptor blockers. Does lipophilicity matter? Basic Res Cardiol 2000;95:I41–145.
  • Ozbek E, Turkoz Y, Gokdeniz R, et al. Increased nitric oxide production in the spermatic vein of patients with varicocele. Eur Urol 2000;37:172–5.
  • Sun Y, Oberley LW, Li Y. A simple method for clinical assay of superoxide dismutase. Clin Chem 1988;34:497–500.
  • Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967;70:158–69.
  • Lowry OH, Rosebrough NJ, Farr AL, et al. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265–75.
  • Jungersten L, Edlund A, Petersson AS, Wennmalm A. Plasma nitrate as an index of nitric oxide formation in man: analyses of kinetics and confounding factors. Clin Physiol 1996;16:369–79.
  • Gules I, Satoh M, Clower BR, et al. Comparison of three rat models of cerebral vasospasm. Am J Physiol Heart Circ Physiol 2002;283:H2551–9.
  • Marbacher S, Fandino J, Kitchen ND. Standard intracranial in vivo animal models of delayed cerebral vasospasm. Br J Neurosurg 2010;24:415–34.
  • Pluta RM, Oldfield EH. Analysis of nitric oxide (NO) in cerebral vasospasm after aneursymal bleeding. Rev Recent Clin Trials 2007;2:59–67.
  • Hong Y, Guo S, Chen S, et al. Beneficial effect of hydrogen-rich saline on cerebral vasospasm after experimental subarachnoid hemorrhage in rats. J Neurosci Res 2012;90:1670–80.
  • McGirt MJ, Parra A, Sheng H, et al. Attenuation of cerebral vasospasm after subarachnoid hemorrhage in mice overexpressing extracellular superoxide dismutase. Stroke 2002;33:2317–23.
  • Gaetani P, Pasqualin A, Rodriguez y, et al. Oxidative stress in the human brain after subarachnoid hemorrhage. J Neurosurg 1998;89:748–54.
  • Lewén A, Matz P, Chan PH. Free radical pathways in CNS injury. J Neurotrauma 2000;17:871–90.
  • Heeba GH, El-Hanafy AA. Nebivolol regulates eNOS and iNOS expressions and alleviates oxidative stress in cerebral ischemia/reperfusion injury in rats. Life Sci 2012;90:388–95.
  • Uzar E, Acar A, Evliyaoğlu O, et al. The anti-oxidant and anti-apoptotic effects of nebivolol and zofenopril in a model of cerebral ischemia/reperfusion in rats. Prog Neuropsychopharmacol Biol Psychiatry 2012;36:22–8.
  • Findlay JM, Nisar J, Darsaut T. Cerebral vasospasm: a review. Can J Neurol Sci 2016;43:15–32.
  • Koenig MA. Management of delayed cerebral ischemia after subarachnoid hemorrhage. Continuum (Minneap Minn) 2012;18:579–97.
  • Akkus NI, Rajpal S, Peter E. Resolution of nebivolol-induced coronary vasospasm by intracoronary nitroglycerin during a coronary angiogram. Rev Port Cardiol 2012;31:825–8.
  • Galderisi M, D’Errico A. Beta-blockers and coronary flow reserve: the importance of a vasodilatory action. Drugs 2008;68:579–90.
  • Lindamood C, Ortiz S, Shaw A, et al. Effects of commonly administered agents and genetics on nebivolol pharmacokinetics: drug-drug interaction studies. J Clin Pharmacol 2011;51:575–85.
  • Sule SS, Frishman W. Nebivolol: new therapy update. Cardiol Rev 2006;14:259–64.

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