A single-center intervention to discontinue postoperative antibiotics after spinal fusion

References

• Lewis A, Czeisler B, Lord A. Prolonged prophylactic antibiotics with neurosurgical drains and devices: are we using them? Do we need them? Am J Infect Control 2016;44:1757–8.
   PubMed Web of Science ®Google Scholar
• Abu Hamdeh S, Lytsy B, Ronne-Engström E. Surgical site infections in standard neurosurgery procedures- a study of incidence, impact and potential risk factors. Br J Neurosurg 2014;28:270–5.
   PubMed Web of Science ®Google Scholar
• Dellit TH, Chan JD, Fulton C, et al. Reduction in clostridium difficile infections among neurosurgical patients associated with discontinuation of antimicrobial prophylaxis for the duration of external ventricular drain placement. Infect Control Hosp Epidemiol 2014;35:589–90.
   PubMed Web of Science ®Google Scholar
• Murphy RKJ, Liu B, Srinath A, et al. No additional protection against ventriculitis with prolonged systemic antibiotic prophylaxis for patients treated with antibiotic-coated external ventricular drains. J Neurosurg 2015;122:1120–6.
   PubMed Web of Science ®Google Scholar
• Flibotte JJ, Lee KE, Koroshetz WJ, Rosand J, McDonald CT. Continuous antibiotic prophylaxis and cerebral spinal fluid infection in patients with intracranial pressure monitors. Ncc 2004;1:61–8.
   Web of Science ®Google Scholar
• May AK, Fleming SB, Carpenter RO, et al. Influence of broad-spectrum antibiotic prophylaxis on intracranial pressure monitor infections and subsequent infectious complications in head-injured patients. Surg Infect (Larchmt) 2006;7:409–17.
   PubMedGoogle Scholar
• Lemaire A, Dombrovskiy V, Batsides G, et al. The effect of Clostridium difficile infection on cardiac surgery outcomes. Surg Infect (Larchmt) 2015;16:24–8.
   PubMed Web of Science ®Google Scholar
• Roberts RR, Hota B, Ahmad I, et al. Hospital and societal costs of antimicrobial-resistant infections in a Chicago teaching hospital: implications for antibiotic stewardship. Clin Infect Dis 2009;49:1175–84.
   PubMed Web of Science ®Google Scholar
• Akalin HE. Surgical prophylaxis: the evolution of guidelines in an era of cost containment. J Hosp Infect 2002;50(Suppl A):S3–S7.
   PubMed Web of Science ®Google Scholar
• Lewis A, Sen R, Hill TC, et al. Antibiotic prophylaxis for subdural and subgaleal drains. J Neurosurg 2017;126:908–12.
   PubMed Web of Science ®Google Scholar
• CDC/NHSN surveillance definitions for specific types of infections. 2014.
   Google Scholar
• Magee G, Strauss ME, Thomas SM, Brown H, Baumer D, Broderick KC. Impact of Clostridium difficile-associated diarrhea on acute care length of stay, hospital costs, and readmission: a multicenter retrospective study of inpatients, 2009-2011. Am J Infect Control 2015;43:1148–53.
   PubMed Web of Science ®Google Scholar
• Haddad S, Millhouse PW, Maltenfort M, Restrepo C, Kepler CK, Vaccaro AR. Diagnosis and neurologic status as predictors of surgical site infection in primary cervical spinal surgery. Spine J 2016;16:632–42.
   PubMed Web of Science ®Google Scholar
• Patel H, Khoury H, Girgenti D, Welner S, Yu H. Burden of surgical site infections associated with select spine operations and involvement of Staphylococcus aureus. Surg Infect (Larchmt) 2016;18:461473.
   Web of Science ®Google Scholar
• Shaffer WO, Matz PG, Baisden J, Fernand R, North American Spine Society Evidence-Based Clinical Guidelines for Multidiscilinary Spine Care. 2013. Available from: https://www.spine.org/Portals/0/Documents/ResearchClinicalCare/Guidelines/AntibioticProphylaxis.pdf
   Google Scholar
• Brown EM, Pople IK, de Louvois J, et al. Spine update: prevention of postoperative infection in patients undergoing spinal surgery. Spine (Phila Pa 1976) 2004;29:938–45.
   PubMed Web of Science ®Google Scholar
• Tubaki VR, Rajasekaran S, Shetty AP. Effects of using intravenous antibiotic only versus local intrawound vancomycin antibiotic powder application in addition to intravenous antibiotics on postoperative infection in spine surgery in 907 patients. Spine (Phila Pa 1976) 2013;38:2149–55.
   PubMed Web of Science ®Google Scholar
• Takemoto RC, Lonner B, Andres T, et al. Appropriateness of twenty-four-hour antibiotic prophylaxis after spinal surgery in which a drain is utilized. J Bone Jt Surgery-American 2015;97:979–86.
   PubMed Web of Science ®Google Scholar
• Marimuthu C, Abraham VT, Ravichandran M, Achimuthu R. Antimicrobial prophylaxis in instrumented spinal fusion surgery: a comparative analysis of 24-hour and 72-hour dosages. Asian Spine J 2016;10:1018–22.
   PubMed Web of Science ®Google Scholar
• Kim B, Moon S-H, Moon E-S, et al. Antibiotic microbial prophylaxis for spinal surgery: comparison between 48 and 72-hour AMP protocols. Asian Spine J 2010;4:71.
   PubMedGoogle Scholar
• Kanayama M, Hashimoto T, Shigenobu K, Oha F, Togawa D. Effective prevention of surgical site infection using a Centers for Disease Control and Prevention guideline–based antimicrobial prophylaxis in lumbar spine surgery. J Neurosurg Spine 2007;6:327–9.
   PubMed Web of Science ®Google Scholar
• Barker FG. Efficacy of prophylactic antibiotic therapy in spinal surgery: a meta-analysis. Neurosurgery 2002;51:391–400.
   PubMed Web of Science ®Google Scholar
• Allegranzi B, Zayed B, Bischoff P, et al. Surgical site infections 2 New WHO recommendations on intraoperative and postoperative measures for surgical site infection prevention: an evidence-based global perspective. Lancet Infect Dis 2016;16:e288–303.
   PubMedGoogle Scholar
• Bratzler DW, Dellinger EP, Olsen KM, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J Health Syst Pharm 2013;70:195–283.
   PubMedGoogle Scholar
• Dimick JB, Lipsett PA, Kostuik JP. Spine update: antimicrobial prophylaxis in spine surgery: basic principles and recent advances. Spine (Phila Pa 1976) 2000;25:2544–8.
   PubMed Web of Science ®Google Scholar
• Collignon P. Antibiotic resistance: are we all doomed? Intern Med J 2015;45:1109–15.
   PubMed Web of Science ®Google Scholar
• Charani E, Castro-Sanchez E, Sevdalis N, et al. Understanding the determinants of antimicrobial prescribing within hospitals: the role of “prescribing etiquette”. Clin Infect Dis 2013;57:188–96.
   PubMed Web of Science ®Google Scholar
• Fridkin SK, Srinivasan A. Implementing a strategy for monitoring inpatient antimicrobial use among hospitals in the United States. Clin Infect Dis 2014;58:401–6.
   PubMed Web of Science ®Google Scholar
• The Joint Commission. Improving America’s hospitals: the Joint Commission’s annual report on quality and safety 2013. 2013. Available from: http://www.jointcommission.org/assets/1/6/TJC_Annual_Report_2013.pdf. [last accessed 15 May 2015].
   Google Scholar
• Khan SA, Rodrigues G, Kumar P, Rao PGM. Current challenges in adherence to clinical guidelines for antibiotic prophylaxis in surgery. J Coll Physicians Surg Pak 2006;16:435–7.
   PubMedGoogle Scholar
• Hepburn-Smith M, Dynkevich I, Spektor M, Lord A, Czeisler B, Lewis A. Establishment of an external ventricular drain best practice guideline: the Quest for a Comprehensive, Universal Standard for External Ventricular Drain Care. J Neurosci Nurs 2016;48:54–65.
   PubMed Web of Science ®Google Scholar
• Little AS, White WL. Prophylactic antibiotic trends in transsphenoidal surgery for pituitary lesions. Pituitary 2011;14:99–104.
   PubMed Web of Science ®Google Scholar
• Joundi RA, Wong BM, Leis JA. Antibiotics “just-in-case” in a patient with aspiration pneumonitis. JAMA Intern Med 2015;175:489–90.
   PubMed Web of Science ®Google Scholar