Magnesium sulphate reduces cell volume in physiological conditions but not in the cytotoxic oedema during global brain ischemia

References

• Farooqui A, Haun S, Horrocks L. Ischemia and hypoxia. Basic neurochemistry: Molecular, cellular and medical aspects, GJ Siegel. Raven Press, New York 1994; 871–872
   Google Scholar
• Zivin JA, Choi DW. Stroke therapy. Scientific American 1991; 265: 56–63
   PubMed Web of Science ®Google Scholar
• Harrison NL, Simmonds MA. Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex. British Journal of Pharmacology 1985; 84: 381–391
   PubMed Web of Science ®Google Scholar
• Muir KW. Magnesium for neuroprotection in ischemic stroke: Rationale for use and evidence of effectiveness. Central Nervous System Drugs 2001; 15: 921–930
   Google Scholar
• Nowak L, Bregestovski P, Ascher P, et al. Magnesium gates glutamate-activated channels in mouse central neurons. Nature 1984; 307: 462–465
   PubMed Web of Science ®Google Scholar
• Sang N, Meng Z. Blockade by magnesium of sodium currents in acutely isolated hippocampal CA1 neurons of rat. Brain Research 2002; 952: 218–221
   PubMed Web of Science ®Google Scholar
• van der Hel WS, van den Bergh WM, Nicolay K, et al. Suppression of cortical spreading depressions after magnesium treatment in the rat. Neuroreport 1998; 9: 2179–2182
   PubMed Web of Science ®Google Scholar
• Tsuda T, Kogure K, Nishioka K, et al. Mg2+administered up to twenty-four hours following reperfusion prevents ischemic damage of the Ca1 neurons in the rat hippocampus. Neuroscience 1991; 44: 335–341
   PubMed Web of Science ®Google Scholar
• Kemp PA, Gardiner SM, Bennett T, et al. Magnesium sulfate reverses the carotid vasoconstriction caused by endotelin-I, angiotensin-II and neuropeptide Y, but not that caused by NG-nitro-L-arginine methyl esther, in conscious rats. Clinical Science 1993; 85: 175–181
   PubMed Web of Science ®Google Scholar
• Chi O, Pollak P, Weiss HR. Effects of magnesium sulfate and nifedipine on regional cerebral blood flow during middle cerebral artery ligation in rats. Archive of International Pharmacodynamic and Therapeutics 1990; 304: 196–205
   PubMedGoogle Scholar
• Greenwood K, Cox P, Mehmet H, et al. Magnesium sulfate treatment after transient hypoxia-ischemia in the newborn piglet does not protect against cerebral damage. Pediatric Research 2000; 48: 346–350
   PubMed Web of Science ®Google Scholar
• Muir KW, Lees KR. Dose optimization of intravenous magnesium sulfate after acute stroke. Stroke 1998; 29: 918–923
   PubMed Web of Science ®Google Scholar
• Izumi Y, Roussel S, Pinard E, et al. Reduction of infarct volume by magnesium after middle cerebral artery occlusion in rats. Journal of Cerebral Flow and Metabolism 1991; 11: 1025–1030
   PubMed Web of Science ®Google Scholar
• Ustun ME, Gurbilek M, Ak A, et al. Effects of magnesium sulfate on tissue lactate and malondialdehyde levels in experimental head trauma. Intensive Care Medicine 2001; 27: 264–268
   PubMed Web of Science ®Google Scholar
• Galvin KA, Oorschot DE. Postinjury magnesium sulfate treatment is not markedly neuroprotective for striatal medium spiny neurons after perinatal hypoxia/ischemia in the rat. Pediatric Research 1998; 44: 740–745
   PubMed Web of Science ®Google Scholar
• Zhu H, Meloni BP, Moore SR, et al. Intravenous administration of magnesium is only neuroprotective following transient global ischemia when present with post-ischemic mild hypothermia. Brain Research 2004; 1014: 53–60
   PubMed Web of Science ®Google Scholar
• Zhu HD, Martin R, Meloni B, et al. Magnesium sulfate fails to reduce infarct volume following transient focal cerebral ischemia in rats. Neuroscience Research 2004; 49: 347–353
   PubMed Web of Science ®Google Scholar
• Demirei M, Ayata C, Dalkara T, et al. Monitoring cellular oedema at single-neuron level by electrical resistance measurements. Journal of Neuroscience Methods 1997; 72: 175–181
   PubMed Web of Science ®Google Scholar
• Itkis M, Ghajar J, Hariri R. The square-wave approach to impedance measurements of brain tissue water dynamics. Journal of Neuroscience Methods 1995; 59: 237–244
   PubMed Web of Science ®Google Scholar
• Oria C, Eblen-Zajjur A. Extrarenal effects of furosemide on normal and ischemic cerebral tissue in the rat. Revista de Neurología 2000; 18: 11–13
   Google Scholar
• National Institute of Health. Guide for the care and use of laboratory animals. NIH, Washington, DC 1987; 86–123
   Google Scholar
• Pellegrino L, Pellegrino A, Cushman A. A stereotaxic atlas of the rat brain. Plenun Press, New York 1981
   Google Scholar
• Marinov MB, Harbaugh KS, Hoopes PJ, et al. Neuroprotective effects of preischemia intraarterial magnesium sulfate in reversible focal cerebral ischemia. Journal of Neurosurgery 1996; 85: 117–124
   PubMed Web of Science ®Google Scholar
• Lin JY, Chung SY, Lin MC, et al. Effects of magnesium sulfate on energy metabolites and glutamate in the cortex during focal cerebral ischemia and reperfusion in the gerbil monitored by a dual-probe microdialysis technique. Life Science 2002; 71: 803–811
   PubMed Web of Science ®Google Scholar
• Nelson RM, Lambert DG, Richard GA, et al. Pharmacology of ischemia-induced glutamate efflux from rat cerebral cortex in vitro. Brain Research 2003; 964: 1–8
   PubMed Web of Science ®Google Scholar
• Thurnau GR, Kemp DB, Jarvis A. Cerebrospinal fluid levels of magnesium in patients with preeclampsia after treatment with intravenous magnesium sulfate: A preliminary report. American Journal of Obstetrics and Gynecology 1987; 157: 1435–1438
   PubMed Web of Science ®Google Scholar
• Zausinger S, Scholler K, Plesnila N, et al. Combination drug therapy and mild hypothermia after transient focal cerebral ischemia in rats. Stroke 2003; 34: 2246–2251
   PubMed Web of Science ®Google Scholar
• Miles AN, Majda BT, Meloni BP, et al. Postischemic intravenous administration of magnesium sulfate inhibits hippocampal CA1 neuronal death after transient global ischemia in rats. Neurosurgery 2001; 49: 1443–1450
   PubMed Web of Science ®Google Scholar
• Kinoshita Y, Ueyama T, Senba E, et al. Expression of c-fos, heat shock protein 70, neurotrophins, and cyclooxygenase-2 mRNA in response to focal cerebral ischemia/reperfusion in rats and their modification by magnesium sulfate. Journal of Neurotrauma 2001; 18: 435–445
   PubMed Web of Science ®Google Scholar
• Auer RN. Non-pharmacologic (physiologic) neuroprotection in the treatment of brain ischemia. Annals of the New York Academy of Science 2001; 939: 271–282
   PubMed Web of Science ®Google Scholar
• Groenendaal F, Rademaker CM, Toet MC, et al. Effects of magnesium sulphate on amplitude-integrated continuous EEG in asphyxiated term neonates. Acta Paediatrica 2002; 91: 1073–1077
   PubMed Web of Science ®Google Scholar
• Weigl M, Tenze G, Steinlechner B, et al. A systematic review of currently available pharmacological neuroprotective agents as a sole intervention before anticipated or induced cardiac arrest. Resuscitation 2005; 65: 21–39
   PubMed Web of Science ®Google Scholar
• Abo M, Yamamuchi H, Chen Z, et al. Behavioural recovery correlated with MRI in a rat experimental stroke model. Brain Injury 2003; 17: 799–808
   PubMed Web of Science ®Google Scholar