Advanced search
Publication Cover
Current Eye Research Volume 32, 2007 - Issue 1
Submit an article Journal homepage
535
Views
16
CrossRef citations to date
0
Altmetric
Original Article

Isolation, Culture, and Characterization of Human Fetal Trabecular Meshwork Cells

Shan Lin Department of Ophthalmology, University of California, San Francisco, San Francisco, California, USA
,
On-Tat Lee Department of Ophthalmology, University of California, San Francisco, San Francisco, California, USA
,
Petros Minasi Department of Ophthalmology, University of California, San Francisco, San Francisco, California, USA
&
Joshua Wong Department of Ophthalmology, University of California, San Francisco, San Francisco, California, USA
Pages 43-50 | Received 07 Sep 2006, Accepted 31 Oct 2006, Published online: 02 Jul 2009

REFERENCES

  • Grant W M. Further studies on the facility of flow through the trabecular meshwork. Arch Ophthal. 1958; 60: 523
  • Alvarado J A, Yun A J, Murphy C G. Juxtacanalicular tissue in primary open angle glaucoma and in nonglaucomatous normals. Arch Ophthal. 1986; 104(10)1517–1528
  • Polansky J R, Fauss D J, Chen P, et al. Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid response gene product. Acta Ophthalmol. 1997; 211(3)126–139
  • Stone E M, Fingert J H, Sheffield V C, et al. Identification of a gene that causes primary open angle glaucoma. Science 1997; 31(275)668–670
  • Caballero M, Liton P B, Challa P, et al. Effects of donor age on proteasome activity and senescence in trabecular meshwork cells. Biochem Biophys Res Commun. 2004; 323(3)1048–1054
  • Schachtschabel D O, Binninger E A, Rohen J W. vitro cultures of trabecular meshwork cells of the human eye as a model system for the study of cellular aging. Arch Gerontol Geriatr. 1989; 9(3)251–262
  • Rhee D J, Tamm E R, Russell P. Donor corneoscleral buttons: a new source of trabecular meshwork for research. Exp Eye Res. 2003; 77(6)749–756
  • Reme C, d'Epinay S L. Periods of development of the normal human chamber angle. Doc Ophthalmol. 1981; 51(3)241–268
  • Cvekl A, Tamm E R. Anterior eye development and ocular mesenchyme: new insights from mouse models and human diseases. Bioessays. 2004; 26: 374–386
  • Polansky J R, Weinreb R N, Baxter J D, Alvarado J. Human trabecular cells. I. Establishment in tissue culture and growth characteristics. Invest Ophthalmol Vis Sci. 1979; 18(10)1043–1049
  • Gospodarowicz D, Ill C. Extracellular matrix and control of proliferation of vascular endothelial cells. J Clin Invest 1980; 65: 1351–1364
  • Ritch R, Shields M B, Krupic T. The Glaucomas. The C.V. Mosby Company, St. Louis 1989; Vol. 1: 12–18
  • Polansky J R, Wood I S, Maglio M T, Alvarado J A. Trabecular meshwork cell culture in glaucoma research: evaluation of biological activity and structural properties of human trabecular cells in vitro. Ophthalmology. 1984; 91(6)580–595
  • Alvarado J A, Wood I, Polansky J R. Human trabecular cells. II. Growth pattern and ultrastructural characteristics. Invest Ophthalmol Vis Sci. 1982; 23(4)464–478
  • Tumminia S J, Mitton K P, Arora J, et al. Mechanical stretch alters the actin cytoskeletal network and signal transduction in human trabecular meshwork cells. Invest Ophthalmol Vis Sci. 1998; 39(8)1361–1371
  • Clark A F, Brotchie D, Read A T, et al. Dexamethasone alters F-actin architecture and promotes cross-linked actin network formation in human trabecular meshwork tissue. Cell Motil Cytoskeleton. 2005; 60(2)83–95
  • Ryder M I, Weinreb R N, Alvarado J, Polansky J. The cytoskeleton of the cultured human trabecular cell. Characterization and drug responses. Invest Ophthalmol Vis Sci. 1988; 29(2)251–260
  • Yun A J, Murphy C G, Polansky J R, et al. Proteins secreted by human trabecular cells. Glucocorticoid and other effects. Invest Ophthalmol Vis Sci. 1989; 30(9)2012–2022
  • Stamer W D, Seftor R E, Snyder R W, Regan J W. Cultured human trabecular meshwork cells express aquaporin-1 water channels. Curr Eye Res. 1995; 14(12)1095–1100
  • Stamer W D, Roberts B C, Howell D N, Epstein D L. Isolation, culture, and characterization of endothelial cells from schlemm's canal. Invest Ophthalmol Vis Sci. 1998; 39(10)1804–1812

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.