216
Views
10
CrossRef citations to date
0
Altmetric
Research Article

Effect of Retinol Palmitate Eye Drops on Experimental Keratoconjunctival Epithelial Damage Induced byn-Heptanol in Rabbit

, , &
Pages 13-18 | Received 08 Apr 2007, Accepted 19 Nov 2007, Published online: 02 Jul 2009

REFERENCES

  • Ubels J L, MacRae S M. Vitamin A is present as retinol in the tears of humans and rabbits. Curr Eye Res. 1984; 3: 815–822
  • Kubo Y, Arimura A, Watanabe Y, Nakayasu K, Kanai A. Effect of vitamin A palmitate on vitamin A-deficient rabbits. J Jpn Ophthalmol Soc. 1999; 103: 729–733
  • Ubels J L, Edelhauser H F, Foley K M, Liao J C, Gressel P. The efficacy of retinoic acid ointment for treatment of xerophthalmia and corneal epithelial wounds. Curr Eye Res. 1985; 4: 1049–1057
  • Kubo Y, Arimura A, Nakayasu K, Kanai A. Effect of vitamin A palmitate on the synthesis of mucins in cultured conjuntiva. J Jpn Ophthalmol Soc. 1999; 103: 580–583
  • Hori Y, Spurr-Michaud S J, Russo C L, Argüeso P, Gipson I K. Effect of retinoic acid on gene expression in human conjunctival epithelium: Secretory phospholipase A2 mediates retinoic acid induction of MUC16. Invest Ophthalmol Vis Sci 2005; 46: 4050–4061
  • Wright P. 1985. Topical retinoic acid therapy for disorders of the outer eye. Trans Ophthalmol Soc UK 1985; 104: 869–874
  • Soong H K, Martin N F, Wagoner M D, Alfonso E, Mandelbaum S H, Laibson P R, Smith R E, Udell I. 1988. Topical retinoid therapy for squamous metaplasia of various ocular surface disorders. A multicenter, placebo-controlled double-masked study. Ophthalmology 1988; 95: 1142–1146
  • Ohashi Y, Watanabe H, Kinoshita S, Hosotani H, Umemoto M, Manabe R. Vitamin A eyedrops for superior limbic keratoconjunctivitis. Am J Ophthalmol. 1988; 105: 523–527
  • Kobayashi T, Tsubota K, Takamura E, Sawa M, Ohashi Y, Usui M. Effect of retinol palmitate as a treatment for dry eye: A cytological evaluation. Ophthalmologica. 1997; 211: 358–361
  • Kessing S V. Mucous gland system of the conjunctiva. A quantitative normal anatomical study. Acta Ophthalmol Suppl 1968; 95: 1
  • Watanabe H, Fabricant M, Tisdale A S, Spurr-Michaud S J, Lindberg K, Gipson I K. Human corneal and conjunctival epithelia produce a mucin-like glycoprotein for the apical surface. Invest Ophthalmol Vis Sci. 1995; 36: 337–344
  • Johansen S, Heegaard S, Prause J U, Rask-Pedersen E. The healing effect of all-trans retinoic acid on epithelial corneal abrasions in rabbits. Acta Ophthalmol Scand 1998; 76: 401–404
  • Araki K, Ohashi Y, Kinoshita S, Hayashi K, Kuwayama Y, Tano Y. Epithelial wound healing in the denervated cornea. Curr Eye Res. 1993; 13: 203–211
  • Ohashi Y, Watanabe T M, Umemoto M, Kinoshita Y H, Kinoshita S, Watanabe H, Manabe R. Effect of vitamin A instillation on corneal and conjuntival disorders. Rinsho Ganka (Jpn J Clin Ophthalmol). 1987; 41: 368–369
  • Lemp M A. Report of the National Eye Institute/Industry workshop on clinical trials in dry eyes. CLAO J. 1995; 21: 221–232
  • Van Bijsterveld O P. Diagnostic tests in the sicca syndrome. Arch Ophthalmol 1969; 82: 10–14
  • Toshida H, Nakata K, Hamano T, Nakamura M, Nguyen D, Beuerman R W. Effect of gefarnate on the ocular surface in squirrel monkeys. Cornea. 2002; 21: 292–299
  • Toshida H, Nakata K, Hamano T, Nakamura M, Nguyen D, Beuerman R. Gefarnate stimulates goblet cell repopulation following an experimental wound to the tarsal conjunctiva in the dry eye rabbit. Adv Exp Med Biol 2002; 506: 353–357, (Pt A)
  • Murakami T, Fujihara T, Nakamura M, Nakata K. P2Y2 receptor elicits PAS-positive glycoprotein secretion from rabbit conjunctival goblet cells in vivo. J Ocul Pharmacol Ther 2003; 19: 345–352
  • Shigemitsu T, Shimizu Y, Majima Y. Effects of mucin ophthalmic solution on epithelial wound healing in rabbit cornea. Ophthalmic Res. 1997; 29: 61–66

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.