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Cornea

Endothelial Wound Repair of the Organ-Cultured Porcine Corneas

ORCID Icon, , , , &
Pages 856-865 | Received 06 Feb 2018, Accepted 24 Mar 2018, Published online: 13 Apr 2018

References

  • Engelmann K, Bohnke M, Friedl P. Isolation and long-term cultivation of human corneal endothelial cells. Invest Ophthalmol Vis Sci. 1988;29:1656–62.
  • Joyce NC, Joyce SJ, Powell SM, Meklir B. EGF and PGE2: effects on corneal endothelial cell migration and monolayer spreading during wound repair in vitro. Curr Eye Res. 1995; 14(7):601–09. doi:10.3109/02713689508998408.
  • Joyce NC. Proliferative capacity of corneal endothelial cells. Exp Eye Res. 2012;95(1):16–23. doi:10.1016/j.exer.2011.08.014.
  • Laule A, Cable MK, Hoffman CE, Hanna C. Endothelial cell population changes of human cornea during life. Arch Ophthalmol. 1978;96:2031–35. doi:10.1001/archopht.1978.03910060419003.
  • Pels E, Beekhuis H, Völker-Dieben HJ. Long term tissue storage for keratoplasty. In: Brightbill FS ed. Corneal surgery, theory, technique & tissue. 3rd ed. Mosby, St. Louis, MO. p. 897–906. 1999.
  • Krabcova I, Studeny P, Jirsova K. Endothelial cell density before and after the preparation of corneal lamellae for Descemet membrane endothelial keratoplasty with a stromal rim. Cornea. 2011;30(12):1436–41. doi:10.1097/ICO.0b013e318212497e.
  • Claerhout I, Maas H, Pels E. European Eye Bank Association Directory Report. 18th ed. 2010. www.europeaneyebanks.org
  • Go W, Wm B, Hf E, Kr K. The corneal endothelium. Normal and pathologic structure and function. Ophthalmology. 1982;89(6):531–90.
  • Hoppenreijs VP, Pels E, Vrensen GF, Oosting J, Treffers WF. Effects of human epidermal growth factor on endothelial wound healing of human corneas. Invest Ophthalmol Vis Sci. 1992;33(6):1946–57.
  • Liu Y, Sun H, Guo P, Hu M, Zhang Y, Tighe S, et al. Characterization and prospective of human corneal endothelial progenitors. Int J Med Sci. 2017;14(8):705–10. doi:10.7150/ijms.19018.
  • Parekh M, Ferrari S, Sheridan C, Kaye S, Ahmed S. Concise Review: an update on the culture of human corneal endothelial cells for transplantation. Stem Cells Transl Med. 2016;5(2):258–64. doi:10.5966/sctm.2015-0181.
  • Katikireddy KR, Schmedt T, Price MO, Price FW, Jurkunas UV. Existence of neural crest-derived progenitor cells in normal and fuchs endothelial dystrophy corneal endothelium. Am J Pathol. 2016;186(10):2736–50. doi:10.1016/j.ajpath.2016.06.011.
  • He Z, Campolmi N, Gain P, Ha Thi BM, Dumollard JM, Duband S, et al. Revisited microanatomy of the corneal endothelial periphery: new evidence for continuous centripetal migration of endothelial cells in humans. Stem Cells. 2012;30(11):2523–34. doi:10.1002/stem.1212.
  • McGowan SL, Edelhauser HF, Pfister RR, Whikehart DR. Stem cell markers in the human posterior limbus and corneal endothelium of unwounded and wounded corneas. Mol Vis. 2007;13:1984–2000.
  • Hara H, Cooper DK. Xenotransplantation: the future of corneal transplantation? Cornea. 2011;30:317–78. doi:10.1097/ICO.0b013e3181f237ef.
  • Choi HJ, Lee JJ, Kim DH, Kim MK, Lee HJ, Ko AY, et al. Blockade of CD40-CD154 costimulatory pathway promotes long-term survival of full-thickness porcine corneal grafts in nonhuman primates: clinically applicable xenocorneal transplantation. Am J Transplant. 2015;15(3):628–41. doi:10.1111/ajt.13057.
  • Lee SE, Mehra R, Fujita M, Roh DS, Long C, Lee W, et al. Characterization of porcine corneal endothelium for xenotransplantation. Semin Ophthalmol. 2014;29(3):127–35. doi:10.3109/08820538.2013.787104.
  • Sullivan TP, Eaglstein WH, Davis SC, Mertz P. The pig as a model for human wound healing. Wound Repair Regen. 2001; 9(2):66–76. doi:10.1046/j.1524-475x.2001.00066.x.
  • Gutierrez K, Dicks N, Glanzner WG, Agellon LB, Bordignon V. Efficacy of the porcine species in biomedical research. Front Genet. 2015;6:293. doi:10.3389/fgene.2015.00293.
  • Elsheikh A, Alhasso D, Rama P. Biomechanical properties of human and porcine corneas. Exp Eye Res. 2008;86(5):783–90. doi:10.1016/j.exer.2008.02.006.
  • Sanchez I, Martin R, Ussa F, Fernandez-Bueno I. The parameters of the porcine eyeball. Graefes Arch Clin Exp Ophthalmol. 2011;249(4):475–82. doi:10.1007/s00417-011-1617-9.
  • Doughty MJ, Zaman ML. Human corneal thickness and its impact on intraocular pressure measures: a review and meta-analysis approach. Surv Ophthalmol. 2000;44(5):367–408. doi:10.1016/S0039-6257(00)00110-7.
  • Heichel J, Wilhelm F, Kunert KS, Hammer T. Topographic findings of the porcine cornea. Med Hypothesis Discov Innov Ophthalmol. 2016;5(4):125–31.
  • Hayes S, Boote C, Lewis J, Sheppard J, Abahussin M, Quantock AJ, et al. Comparative study of fibrillar collagen arrangement in the corneas of primates and other mammals. Anat Rec (Hoboken). 2007;290(12):1542–50. doi:10.1002/ar.20613.
  • Jay L, Brocas A, Singh K, Kieffer JC, Brunette I, Ozaki T. Determination of porcine corneal layers with high spatial resolution by simultaneous second and third harmonic generation microscopy. Opt Express. 2008;16(21):16284–93. doi:10.1364/OE.16.016284.
  • Meurens F, Summerfield A, Nauwynck H, Saif L, Gerdts V. The pig: a model for human infectious diseases. Trends Microbiol. 2012;20(1):50–57. doi:10.1016/j.tim.2011.11.002.
  • Nicholls S, Bailey M, Mitchard L, Dick AD. Can the corneal endothelium of the pig proliferate in vivo? Acta Ophthalmol. 2009;87:0–0. doi:10.1111/j.1755-3768.2009.2271.x.
  • Fujita M, Mehra R. Lee SE, Roh DS, Long C, Funderburgh JL, et al. Comparison of proliferative capacity of genetically-engineered pig and human corneal endothelial cells. Ophthalmic Res. 2013;49(3):127–38. doi:10.1159/000342978.
  • Taylor MJ, Hunt CJ. Dual staining of corneal endothelium with trypan blue and alizarin red S: importance of pH for the dye-lake reaction. Br J Ophthalmol. 1981;65:815–19. doi:10.1136/bjo.65.12.815.
  • Nejepinska J, Juklova K, Jirsova K. Organ culture, but not hypothermic storage, facilitates the repair of the corneal endothelium following mechanical damage. Acta Ophthalmol. 2009;88(4):413–19. doi:10.1111/j.1755-3768.2008.01490.x.
  • Krabcova I, Studeny P, Jirsova K. Endothelial quality of pre-cut posterior corneal lamellae for Descemet membrane endothelial keratoplasty with a stromal rim (DMEK-S): two-year outcome of manual preparation in an ocular tissue bank. Cell Tissue Bank. 2013;14:325–31. doi:10.1007/s10561-012-9327-z.
  • Merjava S, Neuwirth A, Mandys V, Cytokeratins JK. 8 and 18 in adult human corneal endothelium. Exp Eye Res. 2009;89(3):426–31. doi:10.1016/j.exer.2009.04.009.
  • Forest F, Thuret G, Gain P, Dumollard Jm, Peoc’h M, Perrache C, et al. Optimization of immunostaining on flat-mounted human corneas. Mol Vis. 2015;21:1345–56.
  • Bednarz J, Rodokanaki-von Schrenck A, Engelmann K. Different characteristics of endothelial cells from central and peripheral human cornea in primary culture and after subculture. In Vitro Cell Dev Biol Anim. 1998;34(2):149–53. doi:10.1007/s11626-998-0097-7.
  • Whikehart DR, Parikh CH, Vaughn AV, Mishler K, Edelhauser HF. Evidence suggesting the existence of stem cells for the human corneal endothelium. Mol Vis. 2005;11:816–24.
  • Yamagami S, Yokoo S, Mimura T, Takato T, Araie M, Amano S. Distribution of precursors in human corneal stromal cells and endothelial cells. Ophthalmology. 2007;114(3):433–39. doi:10.1016/j.ophtha.2006.07.042.
  • Schultz G, Cipolla L, Whitehouse A, Eiferman R, Woost P, Jumblatt M. Growth factors and corneal endothelial cells: III. Stimulation of adult human corneal endothelial cell mitosis in vitro by defined mitogenic agents. Cornea. 1992;11(1):20–27. doi:10.1097/00003226-199201000-00003.
  • Ayoubi MG, Armitage WJ, Easty DL. Corneal organ culture: effects of serum and a stabilised form of L-glutamine. Br J Ophthalmol. 1996 Aug;80(8):740–44. doi:10.1136/bjo.80.8.740.
  • Lindl T. Zell- und Gewebekultur. 5th ed. Heidelberg: Spektrum Akademischer Verlag; 2002. p. 352.
  • Joyce NC. Proliferative capacity of the corneal endothelium. Prog Retin Eye Res. 2003;22(3):359–89. doi:10.1016/S1350-9462(02)00065-4.
  • Meekins LC, Rosado-Adames N, Maddala R, Zhao JJ, Rao PV, Afshari NA. Corneal endothelial cell migration and proliferation enhanced by rho kinase (ROCK) inhibitors in in vitro and in vivo models. Invest Opthalmol Vis Sci. 2016;57(15):6731. doi:10.1167/iovs.16-20414.
  • Farjo A, McDermott M, Soong HK. Corneal anatomy, physiology, and wound healing. In: Yanoff M, Duker JS eds. Ophthalmology. 3rd ed. Mosby, St. Louis, MO. 203–208. 2009. p. 1552
  • Bhogal M, Matter K, Balda MS, Allan BD. Organ culture storage of pre-prepared corneal donor material for Descemet’s membrane endothelial keratoplasty. Br J Ophthalmol. 2016;100(11):1576–83. doi:10.1136/bjophthalmol-2016-308855.
  • Doughman DJ, Van Horn D, Rodman WP, Byrnes P, Lindstrom RL. Human corneal endothelial layer repair during organ culture. Arch Ophthalmol. 1976;94(10):1791–96. doi:10.1001/archopht.1976.03910040565016.
  • Senoo T, Joyce NC. Cell cycle kinetics in corneal endothelium from old and young donors. Invest Ophthalmol Vis Sci. 2000;41(3):660–67.
  • Mimura T, Joyce NC. Replication competence and senescence in central and peripheral human corneal endothelium. Invest Ophthalmol Vis Sci. 2006;47:1387–96. doi:10.1167/iovs.05-1199.
  • Tamayo-Arango LJ, Baraldi-Artoni SM, Laus JL, Mendes-Vicenti FA, Pigatto JA, Abib FC. Ultrastructural morphology and morphometry of the normal corneal endothelium of adult crossbred pig. Ciencia Rural. 2009;39(1):117–22. doi:10.1590/S0103-84782009000100018.
  • Schroeter J, Meltendorf C, Ohrloff C, Rieck P. Influence of temporary hypothermia on corneal endothelial cell density during organ culture preservation. Graefes Arch Clin Exp Ophthalmol. 2008;246(3):369–72. doi:10.1007/s00417-007-0711-5.
  • Schroeter J, Ruggeri A, Thieme H, Meltendorf C. Impact of temporary hyperthermia on corneal endothelial cell survival during organ culture preservation. Graefes Arch Clin Exp Ophthalmol. 2015;253(5):753–58. doi:10.1007/s00417-014-2903-0.

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