BIRC3 single nucleotide polymorphism associate with asthma susceptibility and the abundance of eosinophils and neutrophils

References

• March ME, Sleiman PM, Hakonarson H. The genetics of asthma and allergic disorders. Discov Med 2011;11:35–45.
   PubMed Web of Science ®Google Scholar
• Poon A, Litonjua AA, Laprise C. Relevance and implication of genetic determinants to asthma pathophysiology. Curr Opin Allergy Clin Immunol 2011;11:407–413.
   PubMed Web of Science ®Google Scholar
• Marsh RA, Villanueva J, Zhang K, Snow AL, Su HC, Madden L, Mody R, Kitchen B, Marmer D, Jordan MB, Risma KA, Filipovich AH, Bleesing JJ. A rapid flow cytometric screening test for X-linked lymphoproliferative disease due to XIAP deficiency. Cytometry B Clin Cytom 2009;76:334–344.
   PubMed Web of Science ®Google Scholar
• McLeish S, Turner SW. Gene-environment interactions in asthma. Arch Dis Child 2007;92:1032–1035.
   PubMed Web of Science ®Google Scholar
• Holloway JW, Yang IA, Holgate ST. Genetics of allergic disease. J Allergy Clin Immunol 2010;125:S81–94.
   Google Scholar
• Bartemes KR, Kita H. Dynamic role of epithelium-derived cytokines in asthma. Clin Immunol 2012;143:222–235.
   PubMed Web of Science ®Google Scholar
• Davies DE, Wicks J, Powell RM, Puddicombe SM, Holgate ST. Airway remodeling in asthma: new insights. J Allergy Clin Immunol 2003;111:215–225.
   PubMed Web of Science ®Google Scholar
• Holgate ST. Asthma: a simple concept but in reality a complex disease. Eur J Clin Iinvest 2011;41:1339–1352.
   PubMed Web of Science ®Google Scholar
• Trautmann A, Kruger K, Akdis M, Muller-Wening D, Akkaya A, Brocker EB, Blaser K, Akdis CA. Apoptosis and loss of adhesion of bronchial epithelial cells in asthma. Int Arch Allergy Immunol 2005;138:142–150.
   PubMed Web of Science ®Google Scholar
• Tumes DJ, Cormie J, Calvert MG, Stewart K, Nassenstein C, Braun A, Foster PS, Dent LA. Strain-dependent resistance to allergen-induced lung pathophysiology in mice correlates with rate of apoptosis of lung-derived eosinophils. J Leukoc Biol 2007;81:1362–1373.
   PubMed Web of Science ®Google Scholar
• Vignola AM, Chiappara G, Gagliardo R, Gjomarkaj M, Merendino A, Siena L, Bousquet J, Bonsignore G. Apoptosis and airway inflammation in asthma. Apoptosis 2000;5:473–485.
   PubMed Web of Science ®Google Scholar
• Choi YE, Butterworth M, Malladi S, Duckett CS, Cohen GM, Bratton SB. The E3 ubiquitin ligase cIAP1 binds and ubiquitinates caspase-3 and −7 via unique mechanisms at distinct steps in their processing. J Biol Chem 2009;284:12772–12782.
   PubMed Web of Science ®Google Scholar
• Eckelman BP, Salvesen GS. The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases. J Biol Chem 2006;281:3254–3260.
   PubMed Web of Science ®Google Scholar
• Herman MD, Moche M, Flodin S, Welin M, Tresaugues L, Johansson I, Nilsson M, Nordlund P, Nyman T. Structures of BIR domains from human NAIP and cIAP2. Acta Crystallogr Sect F Struct Biol Cryst Commun 2009;65:1091–1096.
   PubMedGoogle Scholar
• Burke SP, Smith L, Smith JB. cIAP1 cooperatively inhibits procaspase-3 activation by the caspase-9 apoptosome. J Biol Chem 2010;285:30061–30068.
   PubMed Web of Science ®Google Scholar
• Durkop H, Hirsch B, Hahn C, Stein H. cIAP2 is highly expressed in Hodgkin-Reed-Sternberg cells and inhibits apoptosis by interfering with constitutively active caspase-3. J Mol Med (Berl) 2006;84:132–141.
   PubMed Web of Science ®Google Scholar
• Roy N, Deveraux QL, Takahashi R, Salvesen GS, Reed JC. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J 1997;16:6914–6925.
   PubMed Web of Science ®Google Scholar
• Weber A, Kirejczyk Z, Besch R, Potthoff S, Leverkus M, Hacker G. Proapoptotic signalling through Toll-like receptor-3 involves TRIF-dependent activation of caspase-8 and is under the control of inhibitor of apoptosis proteins in melanoma cells. Cell Death Differ 2010;17:942–951.
   PubMed Web of Science ®Google Scholar
• McComb S, Cheung HH, Korneluk RG, Wang S, Krishnan L, Sad S. cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation. Cell Death Differ 2012;19:1791–1801.
   PubMed Web of Science ®Google Scholar
• Vince JE, Wong WW, Gentle I, Lawlor KE, Allam R, O'Reilly L, Mason K, Gross O, Ma S, Guarda G, Anderton H, Castillo R, Hacker G, Silke J, Tschopp J. Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation. Immunity 2012;36:215–227.
   PubMed Web of Science ®Google Scholar
• Tenev T, Bianchi K, Darding M, Broemer M, Langlais C, Wallberg F, Zachariou A, Lopez J, MacFarlane M, Cain K, Meier P. The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs. Mol Cell 2011;43:432–448.
   PubMed Web of Science ®Google Scholar
• Moulin M, Anderton H, Voss AK, Thomas T, Wong WW, Bankovacki A, Feltham R, Chau D, Cook WD, Silke J, Vaux DL. IAPs limit activation of RIP kinases by TNF receptor 1 during development. EMBO J 2012;31:1679–1691.
   PubMed Web of Science ®Google Scholar
• Bureau F, Seumois G, Jaspar F, Vanderplasschen A, Detry B, Pastoret PP, Louis R, Lekeux P. CD40 engagement enhances eosinophil survival through induction of cellular inhibitor of apoptosis protein 2 expression: Possible involvement in allergic inflammation. J Allergy Clin Immunol 2002;110:443–449.
   PubMed Web of Science ®Google Scholar
• Conte D, Holcik M, Lefebvre CA, Lacasse E, Picketts DJ, Wright KE, Korneluk RG. Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival. Mol Cell Biol 2006;26:699–708.
   PubMed Web of Science ®Google Scholar
• O'Neill AJ, Doyle BT, Molloy E, Watson C, Phelan D, Greenan MC, Fitzpatrick JM, Watson RW. Gene expression profile of inflammatory neutrophils: alterations in the inhibitors of apoptosis proteins during spontaneous and delayed apoptosis. Shock 2004;21:512–518.
   PubMed Web of Science ®Google Scholar
• Damgaard RB, Gyrd-Hansen M. Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity. Discov Med 2011;11:221–231.
   PubMed Web of Science ®Google Scholar
• Gyrd-Hansen M, Meier P. IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer. Nat Rev Cancer 2010;10:561–574.
   PubMed Web of Science ®Google Scholar
• Cheng L, Zhou Z, Flesken-Nikitin A, Toshkov IA, Wang W, Camps J, Ried T, Nikitin AY. Rb inactivation accelerates neoplastic growth and substitutes for recurrent amplification of cIAP1, cIAP2 and Yap1 in sporadic mammary carcinoma associated with p53 deficiency. Oncogene 2010;29:5700–5711.
   PubMed Web of Science ®Google Scholar
• Choschzick M, Tabibzada AM, Gieseking F, Woelber L, Jaenicke F, Sauter G, Simon R. BIRC2 amplification in squamous cell carcinomas of the uterine cervix. Virchows Arch 2012;461:123–128.
   PubMed Web of Science ®Google Scholar
• Rosebeck S, Lucas PC, McAllister-Lucas LM. Protease activity of the API2-MALT1 fusion oncoprotein in MALT lymphoma development and treatment. Future Oncol 2011;7:613–617.
   PubMed Web of Science ®Google Scholar
• Grant JF, Chittleborough CR, Taylor AW, Dal Grande E, Wilson DH, Phillips PJ, Adams RJ, Cheek J, Price K, Gill T, Ruffin RE. The North West Adelaide Health Study: detailed methods and baseline segmentation of a cohort for selected chronic diseases. Epidemiol Perspect In nov 2006;3:4.
   PubMedGoogle Scholar
• Grant JF, Taylor AW, Ruffin RE, Wilson DH, Phillips PJ, Adams RJ, Price K. Cohort Profile: The North West Adelaide Health Study (NWAHS). Int. J. Epidemiol. 2009;38:1479–86.
   PubMed Web of Science ®Google Scholar
• Adams RJ, Wilson DH, Appleton S, Taylor A, Dal Grande E, Chittleborough CR, Ruffin RE. Underdiagnosed asthma in South Australia. Thorax 2003;58:846–850.
   PubMed Web of Science ®Google Scholar
• The International HapMap Project. Nature 2003;426:789–796.
   PubMed Web of Science ®Google Scholar
• Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005;21:263–265.
   PubMed Web of Science ®Google Scholar
• Wang M, Marin A. Characterization and prediction of alternative splice sites. Gene 2006;366:219–227.
   PubMed Web of Science ®Google Scholar
• R Development Core Team. R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2015.
   Google Scholar
• Gonzalez JR, Armengol L, Sole X, Guino E, Mercader JM, Estivill X, Moreno V. SNPassoc: an R package to perform whole genome association studies. Bioinformatics 2007;23:644–645.
   PubMed Web of Science ®Google Scholar
• Sinnwell JP, Schaid D. haplo.stats: Statistical Analysis of Haplotypes with Traits and Covariates when Linkage Phase is Ambiguous. Rochester, NY: R package version 1.5.8; 2012.
   Google Scholar
• Stram DO, Seshan VE. Multi-SNP haplotype analysis methods for association analysis. Meth Mol Biol 2012;850:423–452.
   PubMedGoogle Scholar
• Pollard KS, Dudoit S, van der Laan MJ. Multiple Testing Procedures: R multtest Package and Applications to Genomics. In: Gentleman R, Carey V, Huber W (eds.) Bioinformatics and Computational Biology Solutions Using R and Bioconductor. New York, NY: Springer (Statistics for Biology and Health Series) 2005:249–271.
   Google Scholar
• Kim CW, Kim HK, Vo MT, Lee HH, Kim HJ, Min YJ, Cho WJ, Park JW. Tristetraprolin controls the stability of cIAP2 mRNA through binding to the 3′UTR of cIAP2 mRNA. Biochem Biophys Res Commun 2010;400:46–52.
   PubMed Web of Science ®Google Scholar
• Wenzel SE. Asthma phenotypes: the evolution from clinical to molecular approaches. Nat Med 2012;18:716–725.
   PubMed Web of Science ®Google Scholar
• Mayer BA, Rehberg M, Erhardt A, Wolf A, Reichel CA, Kracht M, Krombach F, Tiegs G, Zahler S, Vollmar AM, Furst R. Inhibitor of apoptosis proteins as novel targets in inflammatory processes. Arterioscler Thromb Vasc Biol 2011;31:2240–2250.
   PubMed Web of Science ®Google Scholar
• Los H, Koppelman GH, Postma DS. The importance of genetic influences in asthma. Eur Respir J 1999;14:1210–1227.
   PubMed Web of Science ®Google Scholar
• Ferreira MA, Matheson MC, Duffy DL, Marks GB, Hui J, Le Souef P, Danoy P, Baltic S, Nyholt DR, Jenkins M, Hayden C, Willemsen G, Ang W, Kuokkanen M, Beilby J, Cheah F, de Geus EJ, Ramasamy A, Vedantam S, Salomaa V, Madden PA, Heath AC, Hopper JL, Visscher PM, Musk B, Leeder SR, Jarvelin MR, Pennell C, Boomsma DI, Hirschhorn JN, Walters H, Martin NG, James A, Jones G, Abramson MJ, Robertson CF, Dharmage SC, Brown MA, Montgomery GW, Thompson PJ, Australian Asthma Genetics C. Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. Lancet 2011;378:1006–1014.
   PubMed Web of Science ®Google Scholar
• Cookson WO, Moffatt MF. Genetics of asthma and allergic disease. Hum Mol Genet 2000;9:2359–2364.
   PubMed Web of Science ®Google Scholar
• Shin HD, Kim LH, Park BL, Choi YH, Park HS, Hong SJ, Choi BW, Lee JH, Park CS. Association of interleukin 18 (IL18) polymorphisms with specific IgE levels to mite allergens among asthmatic patients. Allergy 2005;60:900–906.
   PubMed Web of Science ®Google Scholar
• Ungvari I, Hadadi E, Virag V, Bikov A, Nagy A, Semsei AF, Galffy G, Tamasi L, Horvath I, Szalai C. Implication of BIRC5 in asthma pathogenesis. Int Immunol 2012;24:293–301.
   PubMed Web of Science ®Google Scholar
• Hirota T, Obara K, Matsuda A, Akahoshi M, Nakashima K, Hasegawa K, Takahashi N, Shimizu M, Sekiguchi H, Kokubo M, Doi S, Fujiwara H, Miyatake A, Fujita K, Enomoto T, Kishi F, Suzuki Y, Saito H, Nakamura Y, Shirakawa T, Tamari M. Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma. J Hum Genet 2004;49:370–375.
   PubMed Web of Science ®Google Scholar