Adipokines, asymmetrical dimethylarginine, and pulmonary function in adolescents with asthma and obesity

References

• Beuther DA, Weiss ST, Sutherland ER. Obesity and asthma. Am J Respir Crit Care Med 2006;174:112–119.
   PubMed Web of Science ®Google Scholar
• Yuksel H, Sogut A, Yilmaz O, Onur E, Dinc G. Role of adipokines and hormones of obesity in childhood asthma. AAIR 2012; 4:98–103.
   Google Scholar
• Huang FY, del-Río-Navarro BE, Torres-Alcántara S, Pérez-Ontiveros JA, Pietropaolo-Cienfuegos DR, Bello-González SA, Villafaña S, Bravo G, Hong E. Plasminogen activator inhibitor-1, fibrinogen, and lung function in adolescents with asthma and obesity. Endocr J 2012; 37:135–144.
   Google Scholar
• Huang FY, del-Río-Navarro BE, Sienra-Monge JJL, Torres-Alcántara S, Pérez-Ontiveros JA, Navarro-Olivos E, Martínez-de-Castro GT, Zhao L, Hong E. Endothelial activation and Systemic inflammation in obese asthmatic children. Allergy Asthma Proc 2008; 29:453–460.
   PubMed Web of Science ®Google Scholar
• Marcon A, Corsico, A, Cazzoletti, L, Bugiani, M, Accordini, S, Almar, E, Cerveri, I, Gislason, D, Gulsvik, A, Janson, C, Jarvis, D, Martínez-Moratalla, J, Pin, I, de Marco, R, Therapy and Health Economics Group of the European Community Respiratory Health Survey. Body mass index, weight gain, and other determinants of lung function decline in adult asthma. J Allergy Clin Immunol 2009;123:1069–1074.
   PubMed Web of Science ®Google Scholar
• Santamaria F, Montella S, Greco L, Valerio G, Franzese A, Maniscalco M, Fiorentino G, Peroni D, Pietrobelli A, De Stefano S, Sperlì F, Boner AL. Obesity duration is associated to pulmonary function impairment in obese subjects. Obesity 2011;19:1623–1628.
   PubMed Web of Science ®Google Scholar
• Aaron SD, Fergusson D, Dent R, Chen Y, Vandemheen KL, Dales RE. Effect of weight reduction on respiratory function and airway reactivity in obese women. Chest 2004;125:2046–2052.
   PubMed Web of Science ®Google Scholar
• Rastogi D, Canfield SM, Andrade A, Isasi CR, Hall CB, Rubinstein A, Arens R. Obesity-associated asthma in children—a distinct entity. Chest 2012;141:895–905.
   PubMed Web of Science ®Google Scholar
• Rastogi D, Fraser S, Oh J, Huber AM, Schulman Y, Bhagtani BH, Khan ZS, Tesfa L, Hall CB, Macian F. Inflammation, metabolic dysregulation, and pulmonary function among obese urban adolescents with asthma. Am J Crit Care Med 2015;191:149–160.
   Web of Science ®Google Scholar
• Sood A. Obesity, adipokines, and lung disease. J Appl Physiol 2010;108:744–753.
   PubMed Web of Science ®Google Scholar
• Ahmad T, Mabalirajan U, Ghosh B, Agrawal A. Altered asymmetric dimethyl arginine metabolism in allergically inflamed mouse lungs. Am J Respir Cell Mol Biol 2010;42:3–8.
   PubMed Web of Science ®Google Scholar
• Global Initiative for Asthma. Workshop Report, Global Strategy for Asthma Management and Prevention. Available from: http://www.ginasthma.org/local/uploads/files/GINA_Pocket_2015.pdf. 5p [last accessed 1 December 2015].
   Google Scholar
• Tanner JM. Growth at adolescence. Oxford, UK: Blackwell, 1962.
   Google Scholar
• Polgar G, Promadhat V. Standard values in pulmonary function testing in children: Techniques and standards. Philadelphia, PA; Saunders; 1971.
   Google Scholar
• Shore SA. Obesity and asthma: lessons from animal models. J Appl Physiol 2007;102:516–528.
   PubMed Web of Science ®Google Scholar
• Shore SA. Obesity and asthma: implications for treatment. Curr Opin Pulm Med 2007;13:56–62.
   PubMed Web of Science ®Google Scholar
• Sierra-Honigmann MR, Nath AK, Murakami C, García-Cardeña G, Papapetropoulos A, Sessa WC, Madge LA, Schechner JS, Schwabb MB, Polverini PJ, Flores-Riveros JR. Biological action of leptin as an angiogenic factor. Science 1998;281:1683–1686.
   PubMed Web of Science ®Google Scholar
• Torday JS, Sun H, Wang L, Torres E, Sunday ME, Rubin LP. Leptin mediates the parathyroid hormone-related protein paracrine stimulation of fetal lung maturation. Am J Physiol Lung Cell Mol Physiol 2002;282:L405–410.
   Web of Science ®Google Scholar
• Sood A, Camargo CA, Jr, Ford ES. Association between leptin and asthma in adults. Thorax 2006;61:300–305.
   PubMed Web of Science ®Google Scholar
• Rastogi D, Bhalani K, Hall CB, Isasi CR. Association of pulmonary function with adiposity and metabolic abnormalities in urban minority adolescents. Ann Am Thorac Soc 2014;11:744–752.
   PubMedGoogle Scholar
• Naveed B, Weiden MD, Kwon S, Gracely EJ, Comfort AL, Ferrier N, Kasturiarachchi KJ, Cohen HW, Aldrich TK, Rom WN (2012) Metabolic syndrome biomarkers predict lung function impairment: a nested case-control study. Am J Respir Crit Care Med 2012;185:392–399.
   Google Scholar
• Fenger RV, Gonzalez-Quintela A, Linneberg A, Husemoen LL, Thuesen BH, Aadahl M, Vidal C, Skaaby T, Sainz JC, Calvo E. The relationship of serum triglycerides, serum HDL, and obesity to the risk of wheezing in 85,555 adults. Respir Med 2013;107:816–824.
   PubMed Web of Science ®Google Scholar
• Matsumoto Y, Toyomasu K, Uchimura N, Ishitake T. Low-molecular-weight adiponectin is more closely associated with episodes of asthma than high-molecular weight adiponectin. Endocr J 2013;60:119–125.
   PubMed Web of Science ®Google Scholar
• Hayashikawa Y, Iwata M, Inomata M, Kawagishi Y, Tokui K, Taka C, Kambara K, Okazawa S, Uamada T, Hayashi R, Kamura Y, Okazawa T, Matsui S, Kigawa M, Tobe K. Association of serum adiponectin with asthma and pulmonary function in the Japanese population. Endocr J 2015;62:695–709.
   PubMed Web of Science ®Google Scholar
• Park YH, Kim KW, Lee KE, Kim ES, Sohn MH, Kim KE. Clinical implications of serum retinol-binding protein 4 in asthmatic children. J Kor Med Sci 2009;24:1010–1014.
   PubMed Web of Science ®Google Scholar
• Huang FY, del-Río-Navarro BE, Pérez-Ontiveros JA, Ruiz-Bedolla E, Navarro-Olivos E, Villafaña S, Bravo G, Hong E. Changes in ghrelin and asymmetrical dimethylarginine in obese Mexican adolescents after six-month lifestyle intervention. Endocrine 2013;43:603–610.
   PubMed Web of Science ®Google Scholar
• Gruber HJ, Mayer C, Meinitzer A, Almer G, Horejsi R, Möller R, Pilz S, März W, Gasser R, Truschnig-Wilders M, Mangge H. Asymmetric dimethylarginine (ADMA) is tightly correlated with growth in juveniles without correlations to obesity related disorders. Exp Clin Endocrinol Diabetes 2008;116:520–524.
   PubMed Web of Science ®Google Scholar
• Rudofsky G, Roeder E, Merle T, Hildebrand M, Nawroth PP, Wolfrum C. Weight loss improves endothelial function independently of ADMA reduction in severe obesity. Horm Metab Res 2011;43:343–348.
   PubMed Web of Science ®Google Scholar
• Scott JA, North ML, Rafii M, Huang H, Pencharz P, Subbarao P, Belik J, Grasemann H. Asymmetric dimethylarginine is increased in asthma. Am J Respir Crit Care Med 2011;184:779–785.
   PubMed Web of Science ®Google Scholar
• Carraro S, Giordano G, Piacentini G, Kantar A, Moser S, Cesca L, Berardi M, Di Gangi IM, Baraldi E. Asymmetric dimethylarginine in exhaled breath condensate and serum of children with asthma. Chest 2013;144:405–410.
   PubMed Web of Science ®Google Scholar
• Holguin F, Comhair SAA, Hazen SL, Powers RW, Khatri SS, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Moore WC, Peters SP, Teague WG, Chung KF, Erzurum SC, Wenzel SE. An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype. Am J Respir Crit Care Med 2013;187:153–159.
   PubMed Web of Science ®Google Scholar
• Holguin F1, Comhair SA, Hazen SL, Powers RW, Khatri SS, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Moore WC, Peters SP, Teague WG, Chung KF, Erzurum SC, Wenzel SE. An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype. Am J Respir Crit Care Med 2013;187:153–159.
   PubMed Web of Science ®Google Scholar
• Kattan M, Kumar R, Bloomberg GR, Mitchell HE, Calatroni A, Gergen PJ, Kercsmar CM, Visness CM, Matsui EC, Steinbach SF. Asthma control, adiposity, and adipokines among inner-city adolescents. J Allergy Clin Immunol 2010;125:584–592.
   PubMed Web of Science ®Google Scholar
• Lang JE, Hossain J, Dixon AE, Shade D, Wise RA, Peters SP, Lima JJ. Does age impact the obese asthma phenotype? Longitudinal asthma control, airway function, and airflow perception among mild persistent asthmatics. Chest 2011;40:1524–1533.
   Google Scholar
• Lang JE, Holbrook JT, Wise RA, Dixon AE, Teague WG, Wei CY, Irvin C, Shade D, Lima JJ, for the American Lung Association-Asthma Clinical Research Centers. Obesity in children with poorly-controlled asthma: Sex differences. Pediatr Pulmonol 2013;48: 847–856.
   PubMed Web of Science ®Google Scholar
• Spathopoulos D, Paraskakis E, Trypsianis G, Tsalkidis A, Arvanitidou V, Emporiadou M, Bouros D, Chatzimichael A. The effect of obesity on pulmonary lung function of school aged children in Greece. Pediatr Pulmonol 2009;44:273–280.
   PubMed Web of Science ®Google Scholar
• Ahmed ML, Ong KK, Morrell DJ, Cox L, Drayer N, Perry L, Preece MA, Dunger DB. Longitudinal study of leptin concentrations during puberty: Sex differences and relationship to changes in body composition. J Clin Endocrinol Metab 1999;84:899–905.
   PubMed Web of Science ®Google Scholar
• Rosenbaum M, Nicolson M, Hirsch J, Heymsfield SB, Gallagher D, Chu F, Leibel RL. Effects of gender, body composition, and menopause on plasma concentrations of leptin. J Clin Endocrinol Metab 1996;81:3424–3427.
   PubMed Web of Science ®Google Scholar
• Ruhl CE, Everhart JE. Leptin concentrations in the United States: relations with demographic and anthropometric measures. Am J Clin Nutr 2001;74:295–301.
   PubMed Web of Science ®Google Scholar