Characteristics of non-smoking adult asthma patients with chronic airflow limitation

References

• Brown PJ, Greville HW, Finucane KE. Asthma and irreversible airflow obstruction. Thorax 1984;39(2):131–136.
   PubMed Web of Science ®Google Scholar
• Vonk JM, Jongepier H, Panhuysen CI, Schouten JP, Bleecker ER, Postma DS. Risk factors associated with the presence of irreversible airflow limitation and reduced transfer coefficient in patients with asthma after 26 sources of follow up. Thorax 2003;58(4):322–327.
   PubMed Web of Science ®Google Scholar
• Global Initiative for Chronic Obstructive Lung Disease – Global Initiative for Chronic Obstructive Lung Disease – GOLD. 2016 [cited; Available from: http://goldcopd.org/
   Google Scholar
• Backman KS, Greenberger PA, Patterson R. Airways obstruction in patients with long-term asthma consistent with ‘irreversible asthma’. Chest 1997;112(5):1234–1240.
   PubMed Web of Science ®Google Scholar
• Yii AC, Tan GL, Tan KL, Lapperre TS, Koh MS. Fixed airways obstruction among patients with severe asthma: findings from the Singapore General Hospital-Severe Asthma Phenotype Study. BMC Pulmon Med 2014;14:191.
   PubMed Web of Science ®Google Scholar
• Sterk PJ. Chronic diseases like asthma and COPD: do they truly exist? Eur Respir J 2016;47(2):359–361.
   PubMed Web of Science ®Google Scholar
• Fuhlbrigge AL, Kitch BT, Paltiel AD, Kuntz KM, Neumann PJ, Dockery DW, et al. FEV(1) is associated with risk of asthma attacks in a pediatric population. J Allergy Clin Immunol 2001;107(1):61–67.
   PubMed Web of Science ®Google Scholar
• Kitch BT, Paltiel AD, Kuntz KM, Dockery DW, Schouten JP, Weiss ST, et al. A single measure of FEV1 is associated with risk of asthma attacks in long-term follow-up. Chest 2004;126(6):1875–1882.
   PubMed Web of Science ®Google Scholar
• Loymans RJ, Honkoop PJ, Termeer EH, Snoeck-Stroband JB, Assendelft WJ, Schermer TR, et al. Identifying patients at risk for severe exacerbations of asthma: development and external validation of a multivariable prediction model. Thorax 2016.
   Web of Science ®Google Scholar
• Osborne ML, Pedula KL, O'Hollaren M, Ettinger KM, Stibolt T, Buist AS, Vollmer WM. Assessing future need for acute care in adult asthmatics: the Profile of Asthma Risk Study: a prospective health maintenance organization-based study. Chest 2007;132(4):1151–1161.
   PubMed Web of Science ®Google Scholar
• Connolly CK, Chan NS, Prescott RJ. The relationship between age and duration of asthma and the presence of persistent obstruction in asthma. Postgrad Med J 1988;64(752):422–425.
   PubMed Web of Science ®Google Scholar
• Perret JL, Dharmage SC, Matheson MC, Johns DP, Gurrin LC, Burgess JA, et al. The interplay between the effects of lifetime asthma, smoking, and atopy on fixed airflow obstruction in middle age. Am J Respir Crit Care Med 2013;187(1):42–48.
   PubMed Web of Science ®Google Scholar
• Konstantellou E, Papaioannou AI, Loukides S, Patentalakis G, Papaporfyriou A, Hillas G, et al. Persistent airflow obstruction in patients with asthma: Characteristics of a distinct clinical phenotype. Respir Med 2015;109(11):1404–1409.
   PubMed Web of Science ®Google Scholar
• Anthonisen NR, Connett JE, Murray RP. Smoking and lung function of Lung Health Study participants after 11 sources. Am J Respir Crit Care Med 2002;166(5):675–679.
   PubMed Web of Science ®Google Scholar
• Gan WQ, Man SF, Sin DD. The interactions between cigarette smoking and reduced lung function on systemic inflammation. Chest 2005;127(2):558–564.
   PubMed Web of Science ®Google Scholar
• Bumbacea D, Campbell D, Nguyen L, Carr D, Barnes PJ, Robinson D, et al. Parameters associated with persistent airflow obstruction in chronic severe asthma. Eur Respir J 2004;24(1):122–128.
   PubMed Web of Science ®Google Scholar
• Hudon C, Turcotte H, Laviolette M, Carrier G, Boulet LP. Characteristics of bronchial asthma with incomplete reversibility of airflow obstruction. Ann Allergy Asthma Immunol 1997;78(2):195–202.
   PubMed Web of Science ®Google Scholar
• Ulrik CS, Backer V. Nonreversible airflow obstruction in life-long nonsmokers with moderate to severe asthma. Eur Respir J 1999;14(4):892–896.
   PubMed Web of Science ®Google Scholar
• de Nijs SB, Venekamp LN, Bel EH. Adult-onset asthma: is it really different? Eur Respir Rev 2013;22(127):44–52.
   PubMedGoogle Scholar
• Tan DJ, Walters EH, Perret JL, Burgess JA, Johns DP, Lowe AJ, et al. Clinical and functional differences between early-onset and late-onset adult asthma: a population-based Tasmanian Longitudinal Health Study. Thoraxq 2016.
   Web of Science ®Google Scholar
• Morris JF, Koski A, Johnson LC. Spirometric standards for healthy nonsmoking adults. Am Rev Respir Dis 1971;103(1):57–67.
   PubMed Web of Science ®Google Scholar
• Fabbri LM, Romagnoli M, Corbetta L, Casoni G, Busljetic K, Turato G, et al. Differences in airway inflammation in patients with fixed airflow obstruction due to asthma or chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2003;167(3):418–424.
   PubMed Web of Science ®Google Scholar
• Nathan RA, Sorkness CA, Kosinski M, Schatz M, Li JT, Marcus P, et al. Development of the asthma control test: A survey for assessing asthma control. J Allergy Clin Immunol 2004;113(1):59–65.
   PubMed Web of Science ®Google Scholar
• ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide. Am J Respir Crit Care Med 2005;171(8):912–930.
   PubMed Web of Science ®Google Scholar
• Miller MR. General considerations for lung function testing. Eur Respir J 2005;26(1):153–161.
   PubMed Web of Science ®Google Scholar
• Lee JH, Haselkorn T, Borish L, Rasouliyan L, Chipps BE, Wenzel SE. Risk factors associated with persistent airflow limitation in severe or difficult-to-treat asthma: insights from the TENOR study. Chest 2007;132(6):1882–1889.
   PubMed Web of Science ®Google Scholar
• ten Brinke A, Zwinderman AH, Sterk PJ, Rabe KF, Bel EH. Factors associated with persistent airflow limitation in severe asthma. Am J Respir Crit Care Med 2001;164(5):744–748.
   PubMed Web of Science ®Google Scholar
• Gupta S, Siddiqui S, Haldar P, Raj JV, Entwisle JJ, Wardlaw AJ, et al. Qualitative analysis of high-resolution CT scans in severe asthma. Chest 2009;136(6):1521–1528.
   PubMed Web of Science ®Google Scholar
• Bai TR, Cooper J, Koelmeyer T, Pare PD, Weir TD. The effect of age and duration of disease on airway structure in fatal asthma. Am J Respir Crit Care Med 2000;162(2 Pt 1):663–669.
   PubMed Web of Science ®Google Scholar
• Nelson HS, Davies DE, Wicks J, Powell RM, Puddicombe SM, Holgate ST. Airway remodeling in asthma: New insights. J Allergy Clin Immunol 2003;111(2):215–225.
   PubMed Web of Science ®Google Scholar
• Durrani SR, Viswanathan RK, Busse WW. What effect does asthma treatment have on airway remodeling? Current perspectives. J Allergy Clin Immunol 2011;128(3):439–448; quiz 449–450.
   PubMed Web of Science ®Google Scholar
• Brooks CR, Gibson PG, Douwes J, Van Dalen CJ, Simpson JL. Relationship between airway neutrophilia and ageing in asthmatics and non-asthmatics. Respirology 2013;18(5):857–865.
   PubMed Web of Science ®Google Scholar
• Stern DA, Morgan WJ, Wright AL, Guerra S, Martinez FD. Poor airway function in early infancy and lung function by age 22 sources: a non-selective longitudinal cohort study. Lancet 2007;370(9589): 758–764.
   PubMed Web of Science ®Google Scholar
• McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, et al. Patterns of growth and decline in lung function in persistent childhood asthma. N Engl J Med 2016;374(19):1842–1852.
   PubMed Web of Science ®Google Scholar
• Ulrik CS, Lange P. Decline of lung function in adults with bronchial asthma. Am J Respir Crit Care Med 1994;150(3):629–634.
   PubMed Web of Science ®Google Scholar
• Porsbjerg C, Lange P, Ulrik CS. Lung function impairment increases with age of diagnosis in adult onset asthma. Respir Med 2015;109(7):821–827.
   PubMed Web of Science ®Google Scholar
• Braman SS, Kaemmerlen JT, Davis SM. Asthma in the elderly. A comparison between patients with recently acquired and long-standing disease. Am Rev Respir Dis 1991;143(2):336–340.
   PubMed Web of Science ®Google Scholar
• Connolly MJ, Crowley JJ, Charan NB, Nielson CP, Vestal RE. Reduced subjective awareness of bronchoconstriction provoked by methacholine in elderly asthmatic and normal subjects as measured on a simple awareness scale. Thorax 1992;47(6):410–413.
   PubMed Web of Science ®Google Scholar
• Allen SC, Vassallo M, Khattab A. The threshold for sensing airflow resistance during tidal breathing rises in old age: implications for elderly patients with obstructive airways diseases. Age Ageing 2009;38(5):548–552.
   PubMed Web of Science ®Google Scholar
• Amelink M, de Nijs SB, de Groot JC, van Tilburg PMB, van Spiegel PI, Krouwels FH, et al. Three phenotypes of adult-onset asthma. Allergy 2013;68(5):674–680.
   PubMed Web of Science ®Google Scholar
• Birring SS, Brightling CE, Bradding P, Entwisle JJ, Vara DD, Grigg J, et al. Clinical, radiologic, and induced sputum features of chronic obstructive pulmonary disease in nonsmokers. Am J Respir Crit Care Med 2002;166(8):1078–1083.
   PubMed Web of Science ®Google Scholar
• Berry MA, Hargadon B, McKenna S, Shaw D, Green RH, Brightling CE, et al. Observational study of the natural history of eosinophilic bronchitis. Clin Exp Allergy 2005;35(5):598–601.
   PubMed Web of Science ®Google Scholar
• Bel EH, Wenzel SE, Thompson PJ, Prazma CM, Keene ON, Yancey SW, et al. Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma. N Engl J Med 2014;371(13):1189–1197.
   PubMed Web of Science ®Google Scholar
• Ortega HG, Liu MC, Pavord ID, Brusselle GG, FitzGerald JM, Chetta A, et al. Mepolizumab treatment in patients with severe eosinophilic asthma. N Engl J Med 2014;371(13):1198–1207.
   PubMed Web of Science ®Google Scholar
• Medbo A, Melbye H. Lung function testing in the elderly – can we still use FEV1/FVC <70% as a criterion of COPD? Respir Med 2007;101(6):1097–1105.
   PubMed Web of Science ®Google Scholar
• Bjermer L, Alving K, Diamant Z, Magnussen H, Pavord I, Piacentini G, et al. Current evidence and future research needs for FeNO measurement in respiratory diseases. Respir Med 2014;108(6):830–841.
   PubMed Web of Science ®Google Scholar
• Powell H, Murphy VE, Taylor DR, Hensley MJ, McCaffery K, Giles W, et al. Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: a double-blind, randomised controlled trial. Lancet 2011;378(9795):983–990.
   PubMed Web of Science ®Google Scholar