Impact of a discharge prescription for dexamethasone on outcomes of children treated in the emergency department for acute asthma exacerbations

References

• Bloom B, Cohen RA, Freeman G. Summary health statistics for U.S. children: National Health Interview Survey, 2010. Vital Health Stat 10. 2011;(250):1–80.
   PubMedGoogle Scholar
• Cronin JJ, McCoy S, Kennedy U, An Fhailí SN, Wakai A, Hayden J, Crispino G, Barrett MJ, Walsh S, O’Sullivan R. A randomized trial of single-dose oral dexamethasone versus multidose prednisolone for acute exacerbations of asthma in children who attend the emergency department. Ann Emerg Med. 2016;67(5):593–601.e3. doi:10.1016/j.annemergmed.2015.08.001.
   PubMed Web of Science ®Google Scholar
• Pardue Jones B, Fleming GM, Otillio JK, Asokan I, Arnold DH. Pediatric acute asthma exacerbations: evaluation and management from emergency department to intensive care unit. J Asthma. 2016;53(6):607–617. doi:10.3109/02770903.2015.1067323.
   PubMed Web of Science ®Google Scholar
• Butler K, Cooper WO. Adherence of pediatric asthma patients with oral corticosteroid prescriptions following pediatric emergency department visit or hospitalization. Pediatr Emerg Care. 2004;20(11):730–735. doi:10.1097/01.pec.0000144914.78124.6f.
   PubMed Web of Science ®Google Scholar
• Hames H, Seabrook JA, Matsui D, Rieder MJ, Joubert GI. A palatability study of a flavored dexamethasone preparation versus prednisolone liquid in children. Can J Clin Pharmacol. 2008;15(1):e95-98–e98.
   Google Scholar
• Aljebab F, Alanazi M, Choonara I, Conroy S. Observational study on the palatability and tolerability of oral prednisolone and oral dexamethasone in children in Saudi Arabia and the UK. Arch Dis Child. 2018;103(1):83–88. Cited: in: PMID: 28735259. doi:10.1136/archdischild-2017-312697.
   PubMed Web of Science ®Google Scholar
• Keeney GE, Gray MP, Morrison AK, Levas MN, Kessler EA, Hill GD, Gorelick MH, Jackson JL. Dexamethasone for acute asthma exacerbations in children: a meta-analysis. Pediatrics. 2014;133(3):493–499. Cited: in: PMID: 24515516. doi:10.1542/peds.2013-2273.
   PubMed Web of Science ®Google Scholar
• Altamimi S, Robertson G, Jastaniah W, Davey A, Dehghani N, Chen R, Leung K, Colbourne M. Single-dose oral dexamethasone in the emergency management of children with exacerbations of mild to moderate asthma. Pediatr Emerg Care. 2006;22(12):786–793. doi:10.1097/01.pec.0000248683.09895.08.
   PubMed Web of Science ®Google Scholar
• Cross KP, Paul RI, Goldman RD. Single-dose dexamethasone for mild-to-moderate asthma exacerbations: effective, easy, and acceptable. Can Fam Physician. 2011;57(10):1134–1136.
   PubMed Web of Science ®Google Scholar
• Gries DM, Moffitt DR, Pulos E, Carter ER. A single dose of intramuscularly administered dexamethasone acetate is as effective as oral prednisone to treat asthma exacerbations in young children. J Pediatr. 2000;136(3):298–303. Cited: in: PMID: 10700684. doi:10.1067/mpd.2000.103353.
   PubMed Web of Science ®Google Scholar
• Paniagua N, Lopez R, Muñoz N, Tames M, Mojica E, Arana-Arri E, Mintegi S, Benito J. Randomized trial of dexamethasone versus prednisone for children with acute asthma exacerbations. J Pediatr. 2017;191:190–196.e1. doi:10.1016/j.jpeds.2017.08.030.
   PubMed Web of Science ®Google Scholar
• Watnick CS, Fabbri D, Arnold DH. Single-dose oral dexamethasone is effective in preventing relapse after acute asthma exacerbations. Ann Allergy Asthma Immunol. 2016;116(2):171–172. doi:10.1016/j.anai.2015.11.015.
   PubMed Web of Science ®Google Scholar
• Elkharwili DA, Ibrahim OM, Elazab GA, Elrifaey SM. Two regimens of dexamethasone versus prednisolone for acute exacerbations in asthmatic Egyptian children. Eur J Hosp Pharm. 2020;27(3):151–156. doi:10.1136/ejhpharm-2018-001707.
   PubMedGoogle Scholar
• Rodriguez-Martinez CE, Sossa-Briceño MP, Castro-Rodriguez JA. Dexamethasone or prednisolone for asthma exacerbations in children: a cost-effectiveness analysis. Pediatr Pulmonol. 2020;55(7):1617–1623. doi:10.1002/ppul.24817.
   PubMed Web of Science ®Google Scholar
• Abaya R, Jones L, Zorc JJ. Dexamethasone compared to prednisone for the treatment of children with acute asthma exacerbations. Pediatr Emerg Care. 2018;34(1):53–58. doi:10.1097/PEC.0000000000001371.
   PubMed Web of Science ®Google Scholar
• Kirkland SW, Vandermeer B, Campbell S, Villa-Roel C, Newton A, Ducharme FM, Rowe BH. Evaluating the effectiveness of systemic corticosteroids to mitigate relapse in children assessed and treated for acute asthma: a network meta-analysis. J Asthma. 2019;56(5):522–533. doi:10.1080/02770903.2018.1467444.
   PubMed Web of Science ®Google Scholar
• Sullivan PW, Ghushchyan VH, Globe G, Schatz M. Oral corticosteroid exposure and adverse effects in asthmatic patients. J Allergy Clin Immunol. 2018;141(1):110–116.e7. doi:10.1016/j.jaci.2017.04.009.
   PubMed Web of Science ®Google Scholar
• Bleecker ER, Menzies-Gow AN, Price DB, Bourdin A, Sweet S, Martin AL, Alacqua M, Tran TN. Systematic literature review of systemic corticosteroid use for asthma management. Am J Respir Crit Care Med. 2020;201(3):276–293. doi:10.1164/rccm.201904-0903SO.
   PubMed Web of Science ®Google Scholar
• Bleecker ER, Al-Ahmad M, Bjermer L, Caminati M, Canonica GW, Kaplan A, Papadopoulos NG, Roche N, Ryan D, Tohda Y, et al. Systemic corticosteroids in asthma: a call to action from World Allergy Organization and Respiratory Effectiveness Group. World Allergy Organ J. 2022;15(12):100726. doi:10.1016/j.waojou.2022.100726.
   PubMed Web of Science ®Google Scholar
• Kelly CS, Andersen CL, Pestian JP, Wenger AD, Finch AB, Strope GL, Luckstead EF. Improved outcomes for hospitalized asthmatic children using a clinical pathway. Ann Allergy Asthma Immunol. 2000;84(5):509–516. doi:10.1016/S1081-1206(10)62514-8.Cited: in: PMID: 10831004.
   PubMed Web of Science ®Google Scholar
• Ducharme FM, Chalut D, Plotnick L, Savdie C, Kudirka D, Zhang X, Meng L, McGillivray D. The Pediatric Respiratory Assessment Measure: a valid clinical score for assessing acute asthma severity from toddlers to teenagers. J Pediatr. 2008;152(4):476–480, 480.e1. doi:10.1016/j.jpeds.2007.08.034.
   PubMed Web of Science ®Google Scholar
• Martin M, Penque M, Wrotniak BH, Qiao H, Territo H. Single-dose dexamethasone is not inferior to 2 doses in mild to moderate pediatric asthma exacerbations in the emergency department. Pediatr Emerg Care. 2022;38(6):e1285–e1290. doi:10.1097/PEC.0000000000002727.
   PubMed Web of Science ®Google Scholar
• Stevens MW, Gorelick MH. Short-term outcomes after acute treatment of pediatric asthma. Pediatrics. 2001;107(6):1357–1362. doi:10.1542/peds.107.6.1357.
   PubMed Web of Science ®Google Scholar
• Sampayo EM, Chew A, Zorc JJ. Make an M-PACT on asthma: rapid identification of persistent asthma symptoms in a pediatric emergency department. Pediatr Emerg Care. 2010;26(1):1–5. doi:10.1097/PEC.0b013e3181c32e9d.
   PubMed Web of Science ®Google Scholar
• Bukstein DA, McGrath MM, Buchner DA, Landgraf J, Goss TF. Evaluation of a short form for measuring health-related quality of life among pediatric asthma patients. J Allergy Clin Immunol. 2000;105(2 Pt 1):245–251. doi:10.1016/s0091-6749(00)90072-1.
   PubMed Web of Science ®Google Scholar
• Sharma S, Underdown MJ, Duffin TS, Triplett A, Hanes HC, Jones M, McCalla CD, Wood JK, Woods E, Eby Halvorson E. Systemic glucocorticoid at discharge after hospitalization for pediatric asthma: a prospective pilot study. J Asthma. 2022;59(4):775–779. doi:10.1080/02770903.2021.1879848.
   PubMed Web of Science ®Google Scholar