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LETTER TO THE EDITOR

Absence of JAK2 V617F mutation in gastric cancers

, , , , , , & show all
Pages 222-223 | Received 11 Aug 2005, Published online: 08 Jul 2009

References

  • Aaronson DS, Horvath CM. A road map for those who don't know JAK-STAT. Science 2002; 296: 1653–5
  • Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005; 7: 387–97
  • James C, Ugo V, Le Couedic JP, Staerk J, Delhommeau F, Lacout C, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005; 434: 1144–8
  • To KF, Chan MW, Leung WK, Ng EK, Yu J, Bai AH, et al. Constitutional activation of IL-6-mediated JAK/STAT pathway through hypermethylation of SOCS-1 in human gastric cancer cell line. Br J Cancer 2004; 91: 1335–41
  • Gschwind A, Fischer OM, Ullrich A. The discovery of receptor tyrosine kinases: targets for cancer therapy. Nat Rev Cancer 2004; 4: 361–70

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