611
Views
9
CrossRef citations to date
0
Altmetric
LETTER TO THE EDITOR

Somatic mutation of hCDC4 gene is rare in lung adenocarcinomas

, , , , , , & show all
Pages 487-488 | Received 21 Sep 2005, Published online: 08 Jul 2009

References

  • Strohmaier H, Spruck CH, Kaiser P, Won KA, Sangfelt O, Reed SI. Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line. Nature 2001; 413: 316–22
  • Moberg KH, Bell DW, Wahrer DC, Haber DA, Hariharan IK. Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines. Nature 2001; 413: 311–6
  • Yamanouchi H, Furihata M, Fujita J, Murakami H, Yoshinouchi T, Takahara J, et al. Expression of cyclin E and cyclin D1 in non-small cell lung cancers. Lung Cancer 2001; 31: 3–8
  • Rajagopalan H, Jallepalli PV, Rago C, Velculescu VE, Kinzler KW, Vogelstein B, et al. Inactivation of hCDC4 can cause chromosomal instability. Nature 2004; 428: 77–81
  • Spruck CH, Strohmaier H, Sangfelt O, Muller HM, Hubale KM, Muller-Holzner E, et al. hCDC4 gene mutations in endometrial cancer. Cancer Res 2002; 62: 4535–9
  • Cassia R, Moreno-Bueno G, Rodriguez-Perales S, Hardisson D, Cigudosa JC, Palacios J. Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma. J Pathol 2003; 201: 589–95
  • Ekholm-Reed S, Spruck CH, Sangfelt O, Van Drogen F, Muller-Holzner E, Widschwendter M, et al. Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer. Cancer Res 2004; 64: 795–800
  • Kwak EL, Moberg KH, Wahrer DC, Quinn JE, Gilmore PM, Graham CA, et al. Infrequent mutations of Archipelago (hAGO, hCDC4, Fbw7) in primary ovarian cancer. Gynecol Oncol 2005; 98: 124–8
  • Mao JH, Perez-Losada J, Wu D, Delrosario R, Tsunematsu R, Nakayama KI, Brown K, et al. Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene. Nature 2004; 432: 775–9

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.