542
Views
3
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

Does a local bystander effect necessitate a revision of TCP models that are based on observed clinical data?

, &
Pages 406-411 | Received 17 May 2005, Published online: 08 Jul 2009

References

  • Prise KM, Belyakov OV, Folkard M, Micheal BD. Studies of bystander effect in human fibroblasts using a charged particle microbeam. Int J Radiat Biol 1998; 74: 793–8
  • Randers-Pehrson G, Geard CR, Johnson CD, Elliston CD, Brenner DJ. The Columbia University single-ion microbeam. Radiat Res 2001; 156: 210–14
  • Hall EJ. The bystander effect. Health Physics 2003; 85: 31–5
  • Hall EJ, Hei TK. Genomic instability and bystander effects induced by high-LET radiation. Oncogene 2003; 22: 7034–42
  • Schettino G, Folkard M, Prise KM, Vojnovic B, Held KD, Michael BD. Low-dose studies of bystander cell killing with targeted soft X-Rays. Radiat Res 2003; 160: 505–11
  • Mothersill C, Seymour CB. Radiation-induced bystander effects: Past history and future directions. Radiat Res 2001; 155: 759–67
  • Belyakov OV, Mitchel SA, Parikh D, Randers-Pehrson, Marino S, Amundson SA, et al. Biological effects in unirradiated human tissue induced by radiation damage up to 1 mm away. Proc Natl Acad 2005; 102: 14203–8
  • Mothersill C, O'Malley K, Seymour CB. Characterization of a bystander effect induced in human tissue explant cultures by low LET radiation. Radiat Prot Dosimetry 2002; 99: 163–7
  • Prise KM, Schettino G, Folkard M, Held D. New insights on cell death from radiation exposure. Lancet Oncol 2005; 6(7)520–8
  • Brahme A. Dosimetric precision requirements in radiation therapy. Acta Radiol Oncol 1984; 23: 379–91
  • Bentzen SM, Thames HD. Tumor volume and local control probability: Clinical and radiobiological interpretations. Int J Radiat Oncol Biol Phys 1996; 36: 247–51
  • Goitein M. The probability of controlling an inhomogeneously irradiated tumor. Report of the working group on the evaluation of treatment planning for particle beam radiotherapy, S Zink. National Cancer Institute, Bethesda, MarylandUSA 1987
  • Goitein M, Niemierko A, Okunieff P. Quantitative imaging in Oncology. Proceedings of the 19th LH Gray Conference, K Kaulner, B Carey, A Crellin, RM Harrison. Br Inst Radiol, London 1995; 25–32
  • Fenwick JD. Predicting the radiation control probability of heterogeneous tumor ensembles: Data analysis and parameter estimation using a closed-form expression. Phys Med Biol 1998; 43: 2159–78
  • Nahum AE, Tait DM. Maximizing local control by customized dose prescription for pelvic tumours. Adv. Radiation Therapy Response Monitoring and Treatment Planning, A Breit. Springer, Berlin 1992; 425–31
  • Niemierko A, Goitein M. Implementation of a model for estimating tumor control probability for an inhomogeneously irradiated tumor. Radiother Oncol 1993; 29: 140–7
  • Suit H, Skates S, Taghain A, Okunieff P, Efird JT. Clinical implications of heterogeneity of tumor response to radiation therapy. Radiother Oncol 1992; 25: 251–60
  • Webb S, Nahum AE. The biological effect of inhomogeneous tumor irradiation with inhomogeneous clonogenic cell density. Phys Med Biol 1993; 38: 653–66
  • Zagras GK, Shultheiss TE, Peters LJ. Inter-tumour heterogeneity and radiation dose control curves. Radiother Oncol 1987; 8: 353–62
  • Munro TR, Gilbert CW. The relation between tumour lethal doses and the radiosensitivity of tumour cells. Br J Radiol 1961; 34: 246–51
  • Lindley DV. Introduction to Probability and Statistics: From a Bayesian Viewpoint Part 1, Probability. Cambridge University Press, London 1965
  • Withers HR, Taylor JMG, Maciejewski B. The hazard of accelerated tumor clonogen repopulation during radiotherapy. Acta Oncol 1988; 27: 131–46
  • Roberts SA, Hendry JH. Time factors in larynx tumor radiotherapy: lag times and intertumor heterogeneity in clinical datasets from four centres. Int J Radiat Oncol Biol Phys 1999; 45: 1247–57
  • Withers HR, Thames HD, Peters LJ. A new isoeffect curve for change in dose per fraction. Radiother Oncol 1983; 2: 187–91
  • Fowler JF. The first James Kirk memorial lecture. What is next in fractionated radiotherapy?. Br J Cancer Supp 1984; 6: 285–300
  • Bentzen SM. Steepness of the clinical dose-control curve and variation in the in-vitro radio-sensitivity of head and neck squamous cell carcinoma. Int J Radiat Biol 1992; 62: 417–23
  • Brenner JD. Dose, volume and tumor-control predictions in radiotherapy. Int J Radiat Oncol Biol Phys 1993; 26: 171–9
  • Roberts SA, Hendry JH. A realistic closed-form radiobiological model of clinical tumor-control data incorporating inter-tumor heterogeneity. Int J Radiat Oncol Biol Phys 1998; 41: 689–99
  • Suwinski R, Taylor JMG, Withers HR. The effect of heterogeneity in tumor cell kinetics on radiation dose-response. An exploratory investigation of a plateau effect. Int J Radiat Oncol Biol Phys 1999; 50: 57–66
  • Bentzen SM, Thames HD, Overgaard J. Does variation in the in vitro cellular radiosensitivity explain the shallow clinical dose-control curve for maligmant melanoma. Int J Radiat Biol 1990; 57: 117–26
  • Buffa FM, Davidson SE, Hunter D, Nahum AE, West CML. Incorporating biological measurements (SF2, CFE) in a tumor control probability model increases their prognostic significance: A study in cervical carcinoma treated with radiation therapy. Int J Radiat Oncol Biol Phys 2001; 50: 1113–22
  • Tomé WA, Fowler JF. On the inclusion of the proliferation term into tumour control probability calculations for inhomogeneously irradiated tumours. Phys Med Biol 2003; 48: N261–8
  • Tomé WA, Fowler JF. On cold spots in tumor subvolumes. Med Phys 2002; 29: 1590–8
  • Tomé WA, Meeks SL, Buatti LM, Bova FJ, Friedman WA, Li Z. A high precision system for conformal intracranial radiotherapy. Int J Radiat Oncol Biol Phys 2000; 47: 1137–43
  • Tomé WA, Meeks SL, McNutt TR, Buatti JM, Bova FJ, Friedman WA, et al. Optically guided intensity modulated radiotherapy. Radiotherapy Oncol 2001; 61: 33–44

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.