References
- Huang LE, Bunn HF. Hypoxia inducible factor and its biomedical relevance. J Biol Chem 2003; 278: 19575–8
- Kaelin WG. The von Hippel-Lindau tumor suppressor gene and kidney cancer. Clin Cancer Res 2004; 10: 6290–5s
- White S, Szewczyk JW, Turner JM, Baird EE, Dervan PB. Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands. Nature 1998; 391: 468–71
- Murty MSRC, Sugiyama H. Biology of N-methylpyrrole-N-methylimidazole hairpin polyamide. Biol Pharm Bull 2004; 27: 468–74
- Dervan PB. Molecular recognition of DNA by small molecules. Bioorg Med Chem 2001; 9: 2215–35
- Kielkopf CL, White S, Szewczyk JW, et al. A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA. Science 1998; 282: 111–5
- Wang CC, Ellervik U, Dervan PB. Expanding the recognition of the minor groove of DNA by incorporation of beta-alanine in hairpin polyamides. Bioorg Med Chem 2001; 9: 653–7
- Ayame H, Saito T, Bando T, Fukuda N, Sugiyama H. Fmoc solid-phase synthesis and its application to pyrrole-imidazole polyamides. Nucleic Acids Res 2003; 3: 67–8s
- Gnarra JR, Tory K, Weng Y, Schmidt L, Wei MH, Li H, et al. Mutations of the VHL tumor suppressor gene in renal carcinoma. Nature Genet 1994; 7: 85–90
- Xia G, Kageyama Y, Hayashi T, Kawakami S, Yoshida M, Kihara K. Regulation of vascular endothelial growth factor transcription by endothelial PAS domain protein 1 (EPSA1) and possible involvement of EPAS1 in the angiogenesis of renal cell carcinoma. Cancer 2001; 91: 1429–36
- Huang LE, Gu J, Schau M, Bunn HF. Regulation of hypoxia inducible factor 1α is mediated by an O2-dependent degradation domain via an ubiquitin-proteasome pathway. Proc Natl Acad Sci USA 1998; 95: 7978–92
- Kageyama Y, Koshiji M, To KKW, Tian YM, Ratcliffe PJ, Huang LE. Leu-574 of human HIF-1a is a molecular determinant of prolyl hydroxylation. FASEB J 2004; 18: 1028–30
- Koshiji M, Kageyama Y, Pete EA, Horikawa I, Barret JC, Hunag LE. HIF-1α induces cell cycle arrest functionally counteracting Myc. EMBO J 2004; 23: 1949–56
- Shibata T, Akiyama N, Noda M, Sasai K, Hiraoka M. Enhancement of gene expression under hypoxic conditions using fragments of the human vascular endothelial growth factor and the erythropoietin genes. Int J Radiat Oncol Biol Phys 1998; 42: 913–26
- Takahashi R, Bando T, Sugiyama H. Specific alkylation of human telomere repeats by hairpin pyrrole-imidazole polyamide. Bioorg Med Chem 2003; 11: 2503–9
- Olenyuk BZ, Zhang GJ, Klco JM, Nickols NG, Kaelin WGJr., Dervan PB. Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist. Proc Natl Acad Sci USA 2004; 101: 16768–73
- Oyoshi T, Kawakami W, Narita A, Bando T, Sugiyama H. Inhibition of transcription at a coding sequence by alkylating polyamide. J Am Chem Soc 2003; 125: 4752–4
- Shinohara K, Narita A, Oyoshi T, Bando T, Teraoka H, Sugiyama H. Sequence-specific gene silencing in mammalian cells by alkylating pyrrole-imidazole polyamides. J Am Chem Soc 2004; 126: 5113–8
- Linehan WM, Vasselli J, Srinivasan R, Walther MM, Merino M, Choyke P, et al. Genetic basis of cancer of the kidney: disease-specific approaches to therapy. Clin Cancer Res 2004; 10: 6282–9s
- Iwai A, Fujii Y, Kawakami S, Takazawa R, Kageyama Y, Yoshida MA, et al. Down-regulation of vascular endothelial growth factor in renal cell carcinoma cells by glucocorticoids. Mol Cell Endocrinol 2004; 226: 11–7
- Seagroves T, Johnson RS. Two HIFs may be better than one. Cancer Cell 2002; 1: 211–3