The number of analyzed lymph nodes – a prognostic factor in colorectal cancer

References

• Compton C, Fenoglio-Preiser CM, Pettigrew N, Fielding LP. American Joint Committee on Cancer Prognostic Factors Consensus Conference: Colorectal Working Group. Cancer 2000; 88: 1739–57
   PubMed Web of Science ®Google Scholar
• Benson AB, 3rd. New approaches to the adjuvant therapy of colon cancer. Oncologist 2006; 11: 973–80
   PubMed Web of Science ®Google Scholar
• Joseph NE, Sigurdson ER, Hanlon AL, Wang H, Mayer RJ, MacDonald JS, et al. Accuracy of determining nodal negativity in colorectal cancer on the basis of the number of nodes retrieved on resection. Ann Surg Oncol 2003; 10: 213–8
   PubMed Web of Science ®Google Scholar
• Swanson RS, Compton CC, Stewart AK, Bland KI. The prognosis of T3N0 colon cancer is dependent on the number of lymph nodes examined. Ann Surg Oncol 2003; 10: 65–71
   PubMed Web of Science ®Google Scholar
• Bilchik A. More (nodes) + more (analysis) = less (mortality): Challenging the therapeutic equation for early-stage colon cancer. Ann Surg Oncol 2003; 10: 203–5
   PubMed Web of Science ®Google Scholar
• Bando E, Yonemura Y, Taniguchi K, Fushida S, Fujimura T, Miwa K. Outcome of ratio of lymph node metastasis in gastric carcinoma. Ann Surg Oncol 2002; 9: 775–84
   PubMed Web of Science ®Google Scholar
• Berger AC, Watson JC, Ross EA, Hoffman JP. The metastatic/examined lymph node ratio is an important prognostic factor after pancreaticoduodenectomy for pancreatic adenocarcinoma. Am Surg 2004;70:235–40; Discussion 240.
   PubMed Web of Science ®Google Scholar
• Woodward WA, Vinh-Hung V, Ueno NT, Cheng YC, Royce M, Tai P, et al. Prognostic value of nodal ratios in node-positive breast cancer. J Clin Oncol 2006; 24: 2910–6
   PubMed Web of Science ®Google Scholar
• Jestin P, Pahlman L, Glimelius B, Gunnarsson U. Cancer staging and survival in colon cancer is dependent on the quality of the pathologists' specimen examination. Eur J Cancer 2005; 41: 2071–8
   PubMed Web of Science ®Google Scholar
• Berger AC, Sigurdson ER, Levoyer T, Hanlon A, Mayer RJ, Macdonad JS, et al. Colon cancer survival is associated with decreasing ratio of metastatic to examined lymph nodes. J Clin Oncol 2005; 23: 8706–12
   PubMed Web of Science ®Google Scholar
• Glimelius B, Dahl O, Cedermark B, Jakobsen A, Bentzen SM, Starkhammar H, et al. Adjuvant chemotherapy in colorectal cancer: A joint analysis of randomised trials by the Nordic Gastrointestinal Tumour Adjuvant Therapy Group. Acta Oncol 2005; 44: 904–12
   PubMed Web of Science ®Google Scholar
• Le Voyer TE, Sigurdson ER, Hanlon AL, Mayer RJ, Macdonald JS, Catalano PJ, et al. Colon cancer survival is associated with increasing number of lymph nodes analyzed: A secondary survey of intergroup trial INT-0089. J Clin Oncol 2003; 21: 2912–9
   PubMed Web of Science ®Google Scholar
• Prandi M, Lionetto R, Bini A, Francioni G, Accarpio G, Anfossi A, et al. Prognostic evaluation of stage B colon cancer patients is improved by an adequate lymphadenectomy: Results of a secondary analysis of a large scale adjuvant trial. Ann Surg 2002; 235: 458–63
   PubMed Web of Science ®Google Scholar
• Tepper JE, O'Connell MJ, Niedzwiecki D, Hollis D, Compton C, Benson AB 3rd, et al. Impact of number of nodes retrieved on outcome in patients with rectal cancer. J Clin Oncol 2001; 19: 157–63
   PubMed Web of Science ®Google Scholar
• George S, Primrose J, Talbot R, Smith J, Mullee M, Bailey D, et al. Will Rogers revisited: Prospective observational study of survival of 3 592 patients with colorectal cancer according to number of nodes examined by pathologists. Br J Cancer 2006; 95: 841–7
   PubMed Web of Science ®Google Scholar
• Pages F, Berger A, Camus M, Sanchez-Cabo F, Costes A, Molidor R, et al. Effector memory T cells, early metastasis, and survival in colorectal cancer. N Engl J Med 2005; 353: 2654–66
   PubMed Web of Science ®Google Scholar
• Sobin LH, Greene FL. TNM classification: Clarification of number of regional lymph nodes for pNo. Cancer 2001; 92: 452
   PubMed Web of Science ®Google Scholar
• Wittekind CH WG. Colon and rectum. In: TNM-Classification of malignant tumors. New York, NY: Springer; 1997. p 64–7.
   Google Scholar
• Martling A, Cedermark B, Johansson H, Rutqvist LE, Holm T. The surgeon as a prognostic factor after the introduction of total mesorectal excision in the treatment of rectal cancer. Br J Surg 2002; 89: 1008–13
   PubMed Web of Science ®Google Scholar
• Holm T, Johansson H, Cedermark B, Ekelund G, Rutqvist LE. Influence of hospital- and surgeon-related factors on outcome after treatment of rectal cancer with or without preoperative radiotherapy. Br J Surg 1997; 84: 657–63
   PubMed Web of Science ®Google Scholar
• Smith JA, King PM, Lane RH, Thompson MR. Evidence of the effect of'specialization' on the management, surgical outcome and survival from colorectal cancer in Wessex. Br J Surg 2003; 90: 583–92
   PubMed Web of Science ®Google Scholar
• Baxter NN, Virnig DJ, Rothenberger DA, Morris AM, Jessurun J, Virnig BA. Lymph node evaluation in colorectal cancer patients: A population-based study. J Natl Cancer Inst 2005; 97: 219–25
   PubMed Web of Science ®Google Scholar
• Schmucker DL, Owen RL, Outenreath R, Thoreux K. Basis for the age-related decline in intestinal mucosal immunity. Clin Dev Immunol 2003; 10: 167–72
   PubMedGoogle Scholar
• Tekkis PP, Smith JJ, Heriot AG, Darzi AW, Thompson MR, Stamatakis JD. A national study on lymph node retrieval in resectional surgery for colorectal cancer. Dis Colon Rectum 2006.
   Google Scholar
• Marijnen CA, Nagtegaal ID, Klein Kranenbarg E, Hermans J, van de Velde CJ, Leer JW, et al. No downstaging after short-term preoperative radiotherapy in rectal cancer patients. J Clin Oncol 2001; 19: 1976–84
   PubMed Web of Science ®Google Scholar
• Baxter NN, Morris AM, Rothenberger DA, Tepper JE. Impact of preoperative radiation for rectal cancer on subsequent lymph node evaluation: A population-based analysis. Int J Radiat Oncol Biol Phys 2005; 61: 426–31
   PubMed Web of Science ®Google Scholar
• Fajardo LF. Effects of ionizing radiation on lymph nodes. A review. Front Radiat Ther Oncol 1994; 28: 37–45
   PubMedGoogle Scholar