Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 48, 2024 - Issue 2
52
Views
0
CrossRef citations to date
0
Altmetric
Research Articles

Thrombosis Tendency After Splenectomy in a Danish Family With Hemoglobin Volga, and a Literature Review

, ORCID Icon &
Pages 79-86 | Received 15 Nov 2023, Accepted 23 Mar 2024, Published online: 02 Apr 2024

References

  • Kohne E. Hemoglobinopathies: clinical manifestations, diagnosis, and treatment. Dtsch Arztebl Int. 2011;108(31-32):532–540.
  • Globin Gene Server., https://globin.bx.psu.edu/. Laboratories of Computer Science & Engineering and Biochemistry & Molecular Biology at the Pennsylvania State University.
  • Globin Gene Server, hb variant counter., https://globin.bx.psu.edu/cgi-bin/hbvar/counter. Laboratories of Computer Science & Engineering and Biochemistry & Molecular Biology at the Pennsylvania State University.
  • Ockelford PA, Liang AY, Wells RM, et al. Hemoglobin Volga, beta 27 (B9) Ala replaced by Asp: functional and clinical correlations of an unstable hemoglobin. Hemoglobin. 1980;4(3–4):295–306. doi: 10.3109/03630268008996212.
  • Sözen M, Karaaslan C, Oner R, et al. Severe hemolytic anemia associated with Hb Volga [beta27(B9)Ala–>Asp]: GCC–>GAC at codon 27 in a Turkish family. Am J Hematol. 2004;76(4):378–382. doi: 10.1002/ajh.20128.
  • Luo H-Y, Heeney M, Wang WC, et al. Hemoglobinopathies mimicking Hb S/beta-thalassemia: hb S/S with alpha-thalassemia and Hb S/Volga. Am J Hematol. 2006;81(5):361–365. doi: 10.1002/ajh.20562.
  • Idelson LI, Didkovsky NA, Filippova AV, et al. Haemoglobin Volga, beta27, (B9) Ala leads to Asp, a new highly unstable haemoglobin with a suppressed charge. FEBS Lett. 1975;58(1):122–125. doi: 10.1016/0014-5793(75)80239-0.
  • Loovers HM, Tamminga N, Mulder AB, et al. Clinical course of two children with unstable hemoglobins: the effect of hydroxyurea therapy. Hemoglobin. 2016;40(5):341–344. doi: 10.1080/03630269.2016.1232655.
  • Chan WYK, et al. Successful haploidentical hematopoietic stem cell transplantation (HSCT) and durable engraftment by repeated donor lymphocyte infusions for a Chinese patient with transfusion-dependent hemoglobin (Hb) Hammersmith and massive splenomegaly. Pediatr Transplant. 2022;26(5):e14278.
  • Yıldırım AT, Gülen H, Türkmen H, et al. Successful treatment of a child with hemoglobin hammersmith with hematopoietic stem cell transplantation. Hemoglobin. 2023;47(4):137–139. doi: 10.1080/03630269.2023.2219007.
  • Iolascon A, Andolfo I, Barcellini W, et al. Recommendations regarding splenectomy in hereditary hemolytic anemias. Haematologica. 2017;102(8):1304–1313. doi: 10.3324/haematol.2016.161166.
  • Taher A, Isma’eel H, Mehio G, et al. Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran. Thromb Haemost. 2006;96(4):488–491. doi: 10.1160/TH06-05-0267.
  • Ataga KI. Hypercoagulability and thrombotic complications in hemolytic anemias. Haematologica. 2009;94(11):1481–1484. doi: 10.3324/haematol.2009.013672.
  • Blanke S, Johnsen A, Wimberley PD. Hb Volga [B27 (B9) AlA—AsP], a possible de novo mutation in a Danish person. Hemoglobin. 1989;13(5):489–491. doi: 10.3109/03630268908998087.
  • Wimberley PD, Nielsen IM, Blanke S, et al. Hemoglobinopathies in Danish families. Scand J Clin Lab Invest Suppl. 1989;194:45–49.
  • Glenthøj A, Brieghel C, Nardo-Marino A, et al. Facilitating EMA binding test performance using fluorescent beads combined with next-generation sequencing. EJHaem. 2021;2(4):716–728. doi: 10.1002/jha2.277.
  • Carrell RW, Kay R. A simple method for the detection of unstable haemoglobins. Br J Haematol. 1972;23(5):615–619. doi: 10.1111/j.1365-2141.1972.tb07096.x.
  • van Dijken P, van Wijk R. Revision of the diagnosis of a case of hereditary hemolytic anemia by supravital staining. Blood. 2014;123(18):2758–2758. doi: 10.1182/blood-2014-01-553578.
  • Bello AC. Hemoglobinopathies of difficult diagnosis. Case reports from a main referral pediatric hospital in Venezuela. in Blood. Conference: 55th Annual Meeting of the American Society of Hematology. 2013. New Orleans, LA United States: Hospital de Ninhos JM de los Rios, Caracas, Venezuela.
  • Wang WC, Carter H, Choitz HC, et al. Characterization of Hb Volga [beta 27(B9)Ala–>Asp] and Hb J-Wenchang-Wuming [alpha 11(A9)Lys–>Gln] in the population of the United States. Hemoglobin. 1993;17(1):67–71. doi: 10.3109/03630269308998886.
  • Yates AM, Mortier NA, Hyde KS, et al. The diagnostic dilemma of congenital unstable hemoglobinopathies. Pediatr Blood Cancer. 2010;55(7):1393–1395. doi: 10.1002/pbc.22702.
  • Plaseska D, Koceva S, Rasovic N, et al. Hb Volga [beta 27(B9)Ala–>Asp]: detection of a de novo mutation by Ava II digestion of PCR-amplified DNA. Hemoglobin. 1993;17(3):209–215. doi: 10.3109/03630269308998895.
  • Sciarratta GV, Ivaldi G, Sansone G, et al. Hb Volga or alpha 2 beta 2 27(B9)Ala—Asp in an Italian family. Hemoglobin. 1985;9(1):91–93. doi: 10.3109/03630268508996988.
  • Falcioni G, Grelloni F, Bertoli E, et al. Influence of splenectomy on the properties of erythrocytes with hemoglobin Volga disease. Clin Chim Acta. 1991;196(2-3):153–158. doi: 10.1016/0009-8981(91)90068-n.
  • Kuis-Reerink JD, Jonxis JH, Niazi GA, et al. Hb-Volga or alpha 2 beta 2 27(B9)Ala replaced by Asp. An unstable hemoglobin variant in three generations of a Dutch family. Biochim Biophys Acta. 1976;439(1):63–69. doi: 10.1016/0005-2795(76)90161-6.
  • Brennan SO, et al. Haemoglobin volga: A variant producing congenital haemolytic anaemia. in Christchurch Medical Research Society 20. November 1975. 1975. New Zealand Medical Journal.
  • Sparkenbaugh EM, Henderson MW, Miller-Awe M, et al. Factor XII contributes to thrombotic complications and vaso-occlusion in sickle cell disease. Blood. 2023;141(15):1871–1883. doi: 10.1182/blood.2022017074.
  • Thomsen RW, Schoonen WM, Farkas DK, et al. Risk of venous thromboembolism in splenectomized patients compared with the general population and appendectomized patients: a 10-year nationwide cohort study. J Thromb Haemost. 2010;8(6):1413–1416. doi: 10.1111/j.1538-7836.2010.03849.x.
  • Kristinsson SY, Gridley G, Hoover RN, et al. Long-term risks after splenectomy among 8,149 cancer-free American veterans: a cohort study with up to 27 years follow-up. Haematologica. 2014;99(2):392–398. doi: 10.3324/haematol.2013.092460.
  • Crary SE, Buchanan GR. Vascular complications after splenectomy for hematologic disorders. Blood. 2009;114(14):2861–2868. doi: 10.1182/blood-2009-04-210112.
  • Au NHC, Wong AYK, Vickars L, et al. Two new examples of Hb St. Etienne [beta 92(F8)HisGln] in association with venous thrombosis. Hemoglobin. 2009;33(2):95–100. doi: 10.1080/03630260902817206.
  • Hill QA, Farrar L, Lordan J, et al. A combination of two novel alpha globin variants Hb Bridlington (HBA1) and Hb Taybe (HBA2) resulting in severe hemolysis, pulmonary hypertension, and death. Hematology. 2015;20(1):50–52. doi: 10.1179/1607845414Y.0000000164.
  • Juul MB, Vestergaard H, Petersen J, et al. Thrombosis in Hb Taybe [codons 38/39 (-ACC) (α1)]. Hemoglobin. 2012;36(6):600–604. doi: 10.3109/03630269.2012.746230.
  • Lode HN, Krings G, Schulze-Neick I, et al. Pulmonary hypertension in a case of Hb-Mainz hemolytic anemia. J Pediatr Hematol Oncol. 2007;29(3):173–177. doi: 10.1097/MPH.0b013e318032568c.
  • Thuret I, Bardakdjian J, Badens C, et al. Priapism following splenectomy in an unstable hemoglobin: hemoglobin Olmsted beta 141 (H19) Leu–>Arg. Am J Hematol. 1996;51(2):133–136. doi: 10.1002/(SICI)1096-8652(199602)51:2<133::AID-AJH6>3.3.CO;2-O.
  • Kim B-J, Park K-W, Koh S-B, et al. Stroke induced by splenectomy in hemoglobin Madrid: autopsy clues to the underlying mechanism. Blood Coagul Fibrinolysis. 2005;16(2):141–144. doi: 10.1097/01.mbc.0000161568.59140.a3.
  • Pavlovic S, Kuzmanovic M, Urosevic J, et al. Severe central nervous system thrombotic events in hemoglobin Sabine patient. Eur J Haematol. 2004;72(1):67–70. doi: 10.1046/j.0902-4441.2004.00174.x.
  • Boucher AA, Gurunathan A, Taylor JM, et al. Hemoglobin Southampton complicated by cerebral ischemia, moyamoya, and hydroxyurea-induced methemoglobinemia. Am J Hematol. 2019;94(8):949–954. doi: 10.1002/ajh.25509.
  • Gyan E, Darre S, Jude B, et al. Acute priapism in a patient with unstable hemoglobin Perth and Factor V Leiden under effective oral anticoagulant therapy. Hematol J. 2001;2(3):210–211. doi: 10.1038/sj.thj.6200104.
  • Iizumi T, Suriki H, Sato F, et al. Hb Gunma (beta Gunma) with pulmonary embolism. Intern Med. 1995;34(5):376–379. doi: 10.2169/internalmedicine.34.376.
  • Andrieu V, Dumonceau O, Grange MJ. Priapism in a patient with unstable hemoglobin: hemoglobin Köln. Am J Hematol. 2003;74(1):73–74. doi: 10.1002/ajh.10374.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.