PLGA Nanoparticles for the Oral Delivery of 5-Fluorouracil Using High Pressure Homogenization-Emulsification as the Preparation Method and In Vitro/In Vivo Studies

REFERENCES

• Arbos P., Campanero M. A., Irache J. M. RP-LC determination of 5-fluorouridine in nanoparticulate formulations. J. Pharm. Biomed. Anal. 2002; 28: 857–866
   PubMed Web of Science ®Google Scholar
• Avgoustakis K. Pegylated poly(lactide) and poly(lactide-co-glycolide) nanoparticles: Preparation, properties, and possible applications in drug delivery. Curr. Drug Deliv. 2004; 1: 321–333
   PubMedGoogle Scholar
• Bala I., Bhardwaj V., Hariharan S., et al. Sustained release nanoparticulate formulation containing antioxidant-ellagic acid as potential prophylaxis system for oral administration. J. Drug Target 2006; 14: 27–34
   PubMed Web of Science ®Google Scholar
• Bilati U., Allemann E., Doelker E. Poly(D, L-lactide-co-glycolide) protein-loaded nanoparticles prepared by the double emulsion method–processing and formulation issues for enhanced encapsulation efficiency. J Microencapsul. 2005; 22: 205–214
   PubMed Web of Science ®Google Scholar
• Bodmeier R., McGinity J. W. Polylactic acid microspheres containing quinidine base and quinidine sulphate prepared by the solvent evaporation method. III. Morphology of the microspheres during dissolution studies. J Microencapsul. 1988; 5: 325–330
   PubMed Web of Science ®Google Scholar
• Budhian A., Siegel S. J., Winey K. I. Production of haloperidol-loaded PLGA nanoparticles for extended controlled drug release of haloperidol. J. Microencapsul. 2005; 22: 773–785
   PubMed Web of Science ®Google Scholar
• Chong C. S., Cao M., Wong W. W., et al. Enhancement of T helper type 1 immune responses against hepatitis B virus core antigen by PLGA nanoparticle vaccine delivery. J Contr. Release 2005; 102: 85–99
   PubMed Web of Science ®Google Scholar
• Dong Y., Feng S. S. Poly(d, l-lactide-co-glycolide)/montmorillonite nanoparticles for oral delivery of anticancer drugs. Biomaterials 2005; 26: 6068–6076
   PubMed Web of Science ®Google Scholar
• Govender T., Stolnik S., Garnett, et al. PLGA nanoparticles prepared by nanoprecipitation: Drug loading and release studies of a water soluble drug. J. Contr. Release 1999; 57: 171–185
   PubMed Web of Science ®Google Scholar
• Gutierro I., Hernandez R. M., Igartua M., et al. Size dependent immune response after subcutaneous, oral, and intranasal administration of BSA loaded nanospheres. Vaccine 2002; 21: 67–77
   PubMed Web of Science ®Google Scholar
• Hariharan S., Bhardwaj V., Bala I., Sitterberg J., Bakowsky U., Ravi Kumar M. N. Design of estradiol loaded PLGA nanoparticulate formulations: A potential oral delivery system for hormone therapy. Pharm Res. 2006; 23: 184–195
   PubMed Web of Science ®Google Scholar
• Konan Y. N., Cerny R., Favet J., et al. Preparation and characterization of sterile sub-200 nm meso-tetra(4-hydroxylphenyl)porphyrin-loaded nanoparticles for photodynamic therapy. Eur. J. Pharm. Biopharm. 2003; 55: 115–124
   PubMed Web of Science ®Google Scholar
• Lamprecht A., Ubrich N., Yamamoto H., et al. Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease. J. Pharmacol. Expt. Ther. 2001; 299: 775–781
   PubMed Web of Science ®Google Scholar
• Blanco M. D., Alonso M. J. Development and characterization of protein-loaded poly (lactide-co-glycolide) nanospheres. Eur. J. Pharm. Biopharm. 1997; 43: 287–294
   Web of Science ®Google Scholar
• Peng T., Cheng S. X., Zhuo R. X. Synthesis and characterization of poly-alpha, beta-N-(2-hydroxyethyl) -L-aspartamide-g-poly(L-lactide) biodegradable copolymers as drug carriers. J. Biomed. Mater. Res. A. 2006; 76: 163–173
   PubMedGoogle Scholar
• Quintanar-Guerrero D., Ganem-Quintanar A., Allemann E., et al. Influence of the stabilizer coating layer on the purification and freeze-drying of poly(D, L-lactic acid) nanoparticles prepared by an emulsion-diffusion technique. J. Microencapsul. 1998; 15: 107–119
   PubMed Web of Science ®Google Scholar
• McClean S., Prosser E., Meehan E., et al. Binding and uptake of biodegradable polydl-lactide micro- and nanoparticles in intestinal epithelia. Eur. J. Pharm. Sci. 1998; 6: 153–163
   PubMed Web of Science ®Google Scholar
• Schachter D. M., Kohn J. A synthetic polymer matrix for the delayed or pulsatlie release of water-soluble peptides. J Contr. Release 2002; 78: 143–153
   PubMed Web of Science ®Google Scholar
• Shakweh M., Besnard M., Nicolas V., et al. Poly (lactide-co-glycolide) particles of different physicochemical properties and their uptake by peyer's patches in mice. Eur. J. Pharm. Biopharm. 2005; 61: 1–13
   PubMed Web of Science ®Google Scholar
• Shakweh M., Besnard M., Nicolas V., et al. Poly(lactide-co-glycolide) particles of different physicochemical properties and their uptake by peyer's patches in mice. Eur. J. Pharm. Biopharm. 2005; 61: 1–13
   PubMed Web of Science ®Google Scholar
• Singh J., Pandit S., Bramwell V. W., Alpar H. O. Diphtheria toxoid loaded poly-(epsilon-caprolactone) nanoparticles as mucosal vaccine delivery systems. Methods 2006; 38: 96–105
   PubMed Web of Science ®Google Scholar