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Drug Development and Industrial Pharmacy Volume 34, 2008 - Issue 10
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Research Article

Utility of Multivariate Analysis in Modeling the Effects of Raw Material Properties and Operating Parameters on Granule and Ribbon Properties Prepared in Roller Compaction

Josephine L. P. Soh Department of Industrial and Physical Pharmacy, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, IN, USA
,
Feng Wang Department of Industrial and Physical Pharmacy, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, IN, USA
,
Nathan Boersen Department of Industrial and Physical Pharmacy, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, IN, USA
,
Rodolfo Pinal Department of Industrial and Physical Pharmacy, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, IN, USA
,
Garnet E. Peck Department of Industrial and Physical Pharmacy, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, IN, USA
,
M. Teresa Carvajal Department of Industrial and Physical Pharmacy, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, IN, USACorrespondence[email protected]
,
James Cheney Global Process Analytical Technology, Novartis Pharmaceuticals Corporation, Suffern, New York, USA
,
Hedinn Valthorsson Global Process Analytical Technology, Novartis Pharmaceuticals Corporation, Suffern, New York, USA
&
Jim Pazdan Global Process Analytical Technology, Novartis Pharmaceuticals Corporation, Suffern, New York, USA
 show all
Pages 1022-1035 | Published online: 05 Nov 2008

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  • A. P. G. Gupta, R. W. Miller, and K. R. Morris. (2005c). Effect of the variation in the ambient moisture on the compaction behavior of powder undergoing roller-compaction and on the characteristics of tablets produced from the post-milled granules. J. Pharm. Sci. 94 (10):2314–2326.
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