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ORIGINAL ARTICLE

The use of flupirtine in treatment of tinnitus

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Pages 93-95 | Published online: 08 Jul 2009

References

  • Friedel HA, Fitton A. Flupirtine: a review of its pharmacological properties on therapeutic efficacy in pain states. Drugs 1993; 45: 548–69
  • Kornhuber J, Bleich S, Wiltfang J, Maler M, Parsons CG. Flupirtine shows functional NMDA receptor antagonism by enhancing Mg2 +  block via activation of voltage independent potassium channels. J Neural Transm 1999; 106: 857–67
  • Jastreboff PJ. Phantom auditory perception (tinnitus): mechanisms of generation and perception. Neurosci Res 1990; 8: 221–54
  • Møller AR. Similarities between chronic pain and tinnitus. Am J Otol 1997; 18: 577–85
  • Tonndorf J. The analogy between tinnitus and pain: a suggestion for a physiological basis of chronic tinnitus. Hear Res 1987; 28: 271–5
  • Flor H, Elbert T, Knecht S, Wienbruch C, Pantev C, Birbaumer N, et al. Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation. Nature 1995; 375: 482–4
  • Mühlnickel W, Elbert T, Taub E, Flor H. Reorganization of auditory cortex in tinnitus. Proc Natl Acad Sci U S A 1998; 95: 10340–3
  • Hallam RS, Jakes SC, Hincliffe R. Cognitive variables in tinnitus annoyance. Br J Clin Psychol 1988; 27: 213–22
  • Hiller W, Goebel G. Tinnitus fragenbogen: standardinstrument zur Graduierung de Tinnitus-Schweregrades. HNO 1994; 42: 166–72
  • Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000; 130(4S Suppl)1007S–1015S
  • Nusser Z. AMPA and NMDA receptors: similarities and differences in their synaptic distribution. Curr Opin Neurobiol 2000; 10: 337–41
  • Ma CL, Kelly JB, Wu SH. AMPA and NMDA receptors mediate synaptic excitation in the rat's inferior colliculus. Hear Res 2002; 168: 25–34
  • Puel JL, Ruel J, Guitton M, Wang J, Pujol R. The inner hair cell synaptic complex: physiology, pharmacology and new therapeutic strategies. Audiol Neurootol 2002; 7: 49–54
  • Wu SH, Ma CL, Kelly JB. Contribution of AMPA, NMDA, and GABA(A) receptors to temporal pattern of postsynaptic responses in the inferior colliculus of the rat. J Neurosci 2004; 24: 4625–34
  • Kelly JB, Zhang H. Contribution of AMPA and NMDA receptors to excitatory responses in the inferior colliculus. Hear Res 2002; 168: 35–42
  • Oleskevich S, Walmsley B. Synaptic transmission in the auditory brainstem of normal and congenitally deaf mice. J Physiol 2002; 540(Pt 2)447–55
  • Llinas RR, Ribary U, Jeanmonod D, Kronberg E, Mitra PP. Thalamocortical dysrhythmia: a neurological and neuropsychiatric syndrome characterized by magnetoencephalography. Proc Natl Acad Sci U S A 1999; 96: 15222–7
  • Denk DM, Heinzl H, Franz P, Ehrenberger K. Caroverine in tinnitus treatment. A placebo-controlled blind study. Acta Otolaryngol (Stockh) 1997; 117: 825–30
  • Funahashi M, Stewart M. Properties of gamma-frequency oscillations initiated by propagating population bursts in retrohippocampal regions of rat brain slices. J Physiol 1998; 510(Pt 1)191–208
  • Guitton MJ, Caston J, Ruel J, Johnson RM, Pujol R, Puel JL. Salicylate induces tinnitus through activation of cochlear NMDA receptors. J Neurosci 2003; 23: 3944–52

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