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Clinical and Experimental Hypertension. Part A: Theory and Practice Volume 9, 1987 - Issue 12
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Original Articles

Blood Pressure Changes in Spontaneously Hypertensive and Normotensive Rats with Neonatal Streptozotocin Induced Type 2 Diabetes

M IwaseSecond Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, 812, Japan
,
M KikuchiSecond Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, 812, Japan
,
K NunoiSecond Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, 812, Japan
,
M WakisakaSecond Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, 812, Japan
,
Y MakiSecond Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, 812, Japan
,
S SadoshimaSecond Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, 812, Japan
&
M FujishimaSecond Department of Internal Medicine, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka City, 812, Japan
 show all
Pages 2157-2168 | Published online: 26 Feb 2018

REFERENCES

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  • Kawashima H, Igarashi T, Nakajima Y, Akiyama Y, Usuki K, Ohtake S: Chronic hypertension induced by streptozotocin in rats. Naunyn-Schmiedeberg's Arch Pharmacol 1978; 305: 123–126
  • Kohler L, Boillat N, Luthi P, Atkinson J, Peters-Haefeli L: Influence of streptozotocin-induced diabetes on blood pressure and on renin formation and release. Naunyn-Schmiedeberg's Arch Pharmacol 1980; 313: 257–261
  • Bunag RD, Tornita T, Sasaki S: Streptozotocin diabetic rats are hypertensive despite reduced hypothalamic responsiveness. Hypertension 1982;4: 556–565
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  • Hashimoto Y: Effect of alloxan diabetes induced in spontaneously hypertensive rats. Jap CirculJ 1969; 33: 1315–1338
  • Iams SG, Wexler BC: Alloxan diabetes in spontaneously hypertensive rats. Gravimetric, metabolic and histopathological alterations. Br J exp Path 1977; 58: 177–199
  • Somani P, Singh HP, Saini RK, Rabinovitch A: Streptozotocin-induced diabetes in the spontaneously hypertensive rat. Metabolism 1979; 28: 1075–1077
  • Cavaliere TA, Taylor DG, Kerwin LJ, Antonaccio MJ: Cardiovascular effects of alloxan diabetes in normotensive and spontaneously hypertensive rats. Pharmacology 1980; 20: 211–223
  • Rodgers RL, Breault PH, Sessa WC Jr, Chichester CO: Depressor effect of diabetes in spontaneously hypertensive rat. Role of vascular reactivity and prolyl hydroxylase and lysyl oxidase activities. Life Science 1985;37: 2237–2247
  • Iwase M, Kikuchi M, Nunoi K, Wakisaka M, Maki Y, Sadoshima S, Fujishiraa M: A new model of type 2 (non-insulin-dependent) diabetes mellitus in spontaneously hypertensive rats. Diabetes induced by neonatal streptozotocin treatment. Diabetologia 1986; 29: 808–811
  • Iwase M, Kikuchi M, Nunoi K, Wakisaka M, Maki Y, Sadoshima S, Fujishima M: Diabetes induced by neonatal streptozotocin treatment in spontaneously hypertensive and normotensive rats. Metabolism (in press)

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