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ORIGINAL ARTICLE

The Prevention and Management of Distant Metastases in Women with Breast Cancer

, M.D., Ph.D.
Pages 6-13 | Published online: 11 Jun 2009

REFERENCES

  • Fisher B., Dignam J., Bryant J., Wolmark N. Five versus more than five years of tamoxifen for lymph node-negative breast cancer: updated findings from the National Surgical Adjuvant Breast and Bowel Project B-14 randomized trial. J. Natl. Cancer Inst. 2001; 93(9)684–690
  • Boccardo F., Rubagotti A., Puntoni M., Guglielmini P., Amoroso D. Switching to anastrozole versus continued tamoxifen treatment of early breast cancer: preliminary results of the Italian Tamoxifen Anastrozole trial. J. Clin. Oncol. 2005; 23(22)5138–5147, Epub July 11, 2005
  • Coombes R. C., Hall E., Gibson L. J., Paridaens R., Jassem J. Intergroup Exemestane Study. A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer. N. Engl. J. Med. 2004; 350(11)1081–1092, published correction appears in N. Engl. J. Med. 2004 351, 23 2461
  • Howell A., Cuzick J., Baum M., Buzdar A., Dowsett M. ATAC Trialists' Group. Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. Lancet 2005; 365(9453)60–62
  • Thürlimann B., Keshaviah A., Coates A. S., Mouridsen H., Mauriac L. Breast International Group (BIG) 1-98 Collaborative Group. A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer. N. Engl. J. Med. 2005; 353(26)2747–2757
  • Weigelt B., Glas A. M., Wessels L. F.A., Witteveen A. T., Peterse J. L., van't Veer L. J. Gene expression profiles of primary breast tumors maintained in distant metastases. Proc. Natl. Acad. Sci. 2003; 100(26)15901–15905
  • American Cancer Society. Overview: Breast Cancer, http://www.cancer.org/docroot/CRI/content/CRI_2_2_1X_How_many_people_get_breast_cancer_5.asp Available at: Accessed November 14, 2005
  • Cianfrocca M., Goldstein L. J. Prognostic and predictive factors in early-stage breast cancer. Oncologist 2004; 9(6)606–616
  • Lamerato L., Havstad S., Gandhi S., Jones D., Chlebowski R. Breast cancer recurrence and related mortality in US pts with early breast cancer. 2005 ASCO Annual Meeting Proceedings (post-meeting edition). J. Clin. Oncol. 2005; 25: 62S, (Suppl. 16), (Abstr. 738)
  • Lê M. G., Arriagada R., Spielmann M., Guinebretière J. M., Rochard F. Prognostic factors for death after an isolated local recurrence in patients with early-stage breast carcinoma. Cancer 2002; 94(11)2813–2820
  • Citron M. L., Berry D. A., Cirrincione C., Hudis C., Winer E. P. Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741. J. Clin. Oncol. 2003; 21(8)1431–1439
  • Sorensen S. V., Brown R., Benedict A., Flood E., Revicki D. Patient-rated utilities in postmenopausal early breast cancer (EBC): a cross-country comparison. Value Health 2004; 7(6)641–642
  • Parker B., Sukumar S. Distant metastasis in breast cancer: molecular mechanisms and therapeutic targets. Cancer Biol. Ther. 2003; 2(1)14–21
  • Schmidt-Kittler O., Ragg T., Daskalakis A., Granzow M., Ahr A. From latent disseminated cells to overt metastasis: genetic analysis of systemic breast cancer progression. Proc. Natl. Acad. Sci. USA 2003; 100(13)7737–7742
  • Goldstein N. S., Vicini F. A., Hunter S., Goldstein N. S., Vicini F. A. Molecular clonality determination of ipsilateral recurrence of invasive breast carcinomas after breast-conserving therapy: comparison with clinical and biologic factors. Am. J. Clin. Pathol. 2005; 123(5)679–689
  • Westenend P. J., Meurs C. J.C., Damhuis R. A.M. Tumour size and vascular invasion predict distant metastasis in stage I breast cancer. Grade distinguishes early and late metastasis. J. Clin. Pathol. 2005; 58(2)196–201
  • Braun S., Vogl F. D., Naume B., Janni W., Osborne M. P. A pooled analysis of bone marrow micrometastasis in breast cancer. N. Engl. J. Med. 2005; 353(8)793–802
  • Lawrence G., Pritchard M. G., Kearins O., Casey M. An analysis of breast cancer recurrences for screen detected and symptomatic breast cancers diagnosed in the West Midlands in 1996 and 1997. Breast Cancer Res. Treat. 2005; 94: S211, (Suppl. 1) (Abstr. 5019)
  • Thames H. D., Buchholz T. A., Smith C. D. Frequency of first metastatic events in breast cancer: implications for sequencing of systemic and local-regional treatment. J. Clin. Oncol. 1999; 17: 2649–2658
  • Bijker N., Peterse J. L., Duchateau L., Julien J. P., Fentiman I. S. Risk factors for recurrence and metastasis after breast-conserving therapy for ductal carcinoma-in-situ: analysis of European Organization for Research and Treatment of Cancer Trial 10853. J. Clin. Oncol. 2001; 19(8)2263–2271
  • Vicini F. A., Kestin L., Huang R., Martinez A. Does local recurrence affect the rate of distant metastases and survival in patients with early-stage breast carcinoma treated with breast-conserving therapy?. Cancer 2003; 97(4)910–919
  • Baum M., Demicheli R., Hrushesky W., Retsky M. Does surgery unfavourably perturb the “natural history” of early breast cancer by accelerating the appearance of distant metastases?. Eur. J. Cancer 2005; 41(4)508–515
  • Saphner T., Tormey D. C., Gray R. Annual hazard rates of recurrence for breast cancer after primary therapy. J. Clin. Oncol. 1996; 14(10)2738–2746
  • Hortobagyi G. N., Kau S. W., Buzdar A. U., Theriault R. L., Booser D. J., Gwyn K., Valero V. UT M.D. Anderson Cancer Center, Houston, TX. What is the prognosis of patients with operable breast cancer (BC) five years after diagnosis? 2004 ASCO Annual Meeting Proceedings (post-meeting edition). J. Clin. Oncol. 2004; 22, (Suppl. 14)(Abstr. 585)
  • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 2005; 365(9472)1687–1717
  • Glück S. Adjuvant chemotherapy for early breast cancer: optimal use of epirubicin. Oncologist 2005; 10(10)780–791
  • Bonadonna G., Valagussa P., Moliterni A., Zambetti M., Brambilla C. Adjuvant cyclophosphamide, methotrexate, and fluorouracil in node-positive breast cancer: the results of 20 years of follow-up. N. Engl. J. Med. 1995; 332(14)901–906
  • Bonadonna G., Moliterni A., Zambetti M., Daidone M. G., Pilotti S., Gianni L., Valagussa P. 30 years' follow up of randomised studies of adjuvant CMF in operable breast cancer: cohort study. BMJ 2005; 330(7485)217
  • Fisher B., Dignam J., Mamounas E. P., Costantino J. P., Wickerham D. L. Sequential methotrexate and fluorouracil for the treatment of node-negative breast cancer patients with estrogen receptor-negative tumors: eight-year results from National Surgical Adjuvant Breast and Bowel Project (NSABP) B-13 and first report of findings from NSABP B-19 comparing methotrexate and fluorouracil with conventional cyclophosphamide, methotrexate, and fluorouracil. J. Clin. Oncol. 1996; 14(7) 1982–1992
  • Bonadonna G., Brusamolino E., Valagussa P., Rossi A., Brugnatelli L. Combination chemotherapy as an adjuvant treatment in operable breast cancer. N. Engl. J. Med. 1976; 294(8)405–410
  • Goss P. E., Ingle J. N., Martino S., Robert N. J., Muss H. B. Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA.17. J. Natl. Cancer Inst. 2005; 97(17)1262–1271
  • Winer E. P., Hudis C., Burstein H. J., Wolff A. C., Pritchard K. I. American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for postmenopausal women with hormone receptor-positive breast cancer: status report 2004. J. Clin. Oncol. 2005; 23(3)619–629
  • Buzdar A. U.; on behalf of the ATAC Trialists' group. Impact of adjuvant chemotherapy prior to endocrine therapy: 68 month results from the Arimidex, Tamoxifen, Alone or in Combination (ATAC) trial. 2005 ASCO Annual Meeting Proceedings. J. Clin. Oncol. 2005; 23: 309, (Suppl. 16), (Abstr. 608)
  • Anastrozole [package insert]. AstraZeneca Pharmaceuticals LP, Wilmington, DE 2002
  • Jakesz R., Jonat W., Gnant M., Mittlboeck M., Greil R. On behalf of the ABCSG and the GABG. Switching of postmenopausal women with endocrine-responsive early breast cancer to anastrozole after 2 years' adjuvant tamoxifen: combined results of ABCSG trial 8 and ARNO 95 trial. Lancet 2005; 366(9484)455–462
  • Jelovac D., Macedo L., Handratta V., Long B. J., Goloubeva O. G., Ingle J. N., Brodie A. M. Effects of exemestane and tamoxifen in a postmenopausal breast cancer model. Clin. Cancer Res. 2004; 10(21)7375–7381
  • Geisler J., Haynes B., Anker G., Dowsett M., Lønning P. E. Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study. J. Clin. Oncol. 2002; 20(3)751–757
  • Rose C., Vtoraya O., Pluzanska A., Davidson N., Gershanovich M. An open randomised trial of second-line endocrine therapy in advanced breast cancer. Comparison of the aromatase inhibitors letrozole and anastrozole. Eur. J. Cancer 2003; 39(16)2318–2327
  • Mauriac L., Keshaviah A., Debled M., Mouridsen H., Forbes J. Predictors of early relapse in postmenopausal women with hormone receptor positive breast cancer in the BIG 1-98 trial. Ann. Oncol. Feb 14, 2007, Epub ahead of print
  • Coombes R. C., Paridaens R., Jassem J. First mature analysis of the Intergroup Exemestane Study. J. Clin. Oncol. 2006; 24: 933s, (Suppl. 18) (Abstr. LBA 527)
  • Pritchard K. I. Aromatase inhibitors in adjuvant therapy of breast cancer: before, instead of, or beyond tamoxifen. J. Clin. Oncol. 2005; 23(22)4850–4852
  • Houghton J.; on behalf of the ATAC Trialists' Group. Using anastrozole as initial adjuvant treatment prevents early recurrences and reduces adverse events: updated data from the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial. 2005 ASCO Annual Meeting Proceedings (post-meeting edition). J. Clin. Oncol. 2005; 23: 24S, (Suppl. 16) (Abstr. 582)
  • Baum M., Cuzick J., Howell A., Buzdar A., Demicheli R., Greco M., Retsky M., Hrushesky B.; on behalf of the ATAC Trialists' Group and the Milan Institute. An exploration of relapse data by hazard rate as a means of developing biological insights into the natural history and treatment of breast cancer: data from the Arimidex, Tamoxifen, Alone or in Combination (ATAC) trial and the Milan Institute database. 2005 ASCO Annual Meeting Proceedings (post-meeting edition). J. Clin. Oncol. 2005; 25: 31S, (Suppl. 16) (Abstr. 612)
  • Houghton J.; on behalf of the ATAC Trialists' Group. Intial adjuvant therapy with ANA (S) reduced rates of early breast cancer recurrent and adverse events compared with TAM (T)-data reported on behalf of the ATAC (‘Arimidex’, TAM, Alone or in Cbomination) Trialists' group. Ann. Oncol. 2006; 17: ix93, (Suppl. 9) (Abstr. 243PD)
  • Jung J., Hwang G., Lee Y., Park H., Yang Y. Pamidronate as adjuvant treatment for prevention of bone metastasis in breast cancer. 2005 ASCO Annual Meeting Proceedings (post-meeting edition). J. Clin. Oncol. 2005; 23: 99S, (Suppl. 16) (Abstr. 888)
  • Theriault R. L., Lipton A., Hortobagyi G. N., Leff R., Glück S. Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: a randomized, placebo-controlled trial. Protocol 18 Aredia Breast Cancer Study Group. J. Clin. Oncol. 1999; 17(3)846–854
  • López-Guerrero J. A., Llombart-Cussac A., Noguera R., Navarro S., Pellin A., Almenar S., Vazquez-Alvadalejo C., Llombart-Bosch A. HER2 amplification in recurrent breast cancer following breast-conserving therapy correlates with distant metastasis and poor survival. Int. J. Cancer. 2006; 118(7)1743–1749, Epub October 10, 2005
  • Romond E. H., Perez E. A., Bryant J., Suman V. J., Geyer C. E., Jr. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N. Engl. J. Med. 2005; 353(16)1673–1684
  • Romond E. H. Breast Cancer Update, www.breastcancerupdate.com/bcu2005/6/romond.htm. Available at: Accessed October 31, 2005
  • Cavenee W. K., White R. L. The genetic basis of cancer. Sci. Am. 1995; 272(3)72–79
  • Rugo H. S. Bevacizumab in the treatment of breast cancer: rationale and current data. Oncologist 2004; 9: 43–49, (Suppl. 1)
  • The CAT study: atamestane plus toremifene versus letrozole in advanced breast cancer, http://www.clinicaltrials.gov/ct/gui/show/NCT00097344 Available at: ClinicalTrials.gov 2005 Accessed June 30, 2005
  • Sierra A. Metastases and their microenvironments: linking pathogenesis and therapy. Drug Resist. Update. 2005; 8(4)247–257
  • Malek K., Fink A. K., Thwin S. S., Gurwitz J., Ganz P. A., Silliman R. A. The relationship among physicians' specialty, perceptions of the risks and benefits of adjuvant tamoxifen therapy, and its recommendation in older patients with breast cancer. Med. Care 2004; 42(7)700–706
  • Jakesz R., Samonigg H., Greil R., Gnant M., Schmid M., Kwasny W., Kubista E., Mlineritsch B., Tausch C., Stierer M.; on behalf of the ABCSG. Extended adjuvant treatment with anastrozole: results from the Austrian Breast and Colorectal Cancer Study Group Trial 6a (ABCSG-6a). 2005 ASCO Annual Meeting Proceedings (post-meeting edition). J. Clin. Oncol. 2005; 23: 10S, (Suppl. 16) (Abstr. 526)
  • Mansell J., Moneypenny I. J., Skene A. I. Predictors of early recurrence in postmenopausal women with operable breast cancer. Breast Cancer Research and Treatment. 2006; 100, (Suppl. 1). (Abstr. 2091)

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