REFERENCES
- Herben V. M., ten Bokkel Huinink W. W., Beijnen J. H. Clinical pharmacokinetics of topotecan [J]. Clin. Pharmacokinet 1996; 31: 85–102
- Iyer L., Ratain M. J. Clinical pharmacology of camptothecins [J]. Cancer Chemother. Pharmacol. 1998; 42: S31–43
- Emerson D. L., Besterman J. M., Brown H. R.S., Evans M. G., Leitner P. P., Luzzio M. J., Shaffer J. E., Sternbach D. D., Uehling D, Vuong A. In vivo antitumor of two new seven-substituted water-soluble camptothecin analogues [J]. Cancer Res. 1995; 55(3)603–609
- Hsiang Y. H., Liu L. F. Indentification of mammalian DNA topoisomerase ?as an intracellular target of the anticancer drug camptothecin [J]. Cancer Res. 1988; 48(7)1722–1729
- Liu L. F. DNA topoisomerase poisons as antitumor agent [J]. Annu. Rev. Biochem. 1989; 58: 351–375
- Downes C. S., Johnson R. T. DNA topoisomerases and DNA repair [J]. Bioessays 1988; 8(6)179–184
- Roca J. The mechanisms of DNA topoisomerase [J]. Trends Biochem. Sci. 1995; 20(4)156–160
- Wang J. C. DNA topoisomerase [J]. Annu. Rev. Biochem. 1996; 65: 635–692
- Pommier Y., Leteurtre F., Fesen M. R., Fujimori A., Bertrand R., Solary E., Kohlhagen G., Kohn K. W. Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitor [J]. Cancer Investig. 1994; 12(5)530–542
- Liu L. F., Duann P, Lin C. T., D'Arpa P, Wu J. Mechanism of action of camptothecin [J]. Ann. NY Acad. Sci. 1996; 803: 44–49
- Uckun F. M., Stewart C. F., Reaman G, Chelstrom L. M., Jin J, Chandan-Langlie M, Waddick K. G., White J, Evans W. E. In vitro and in vivo activity of topotecan against human B-lineage acute lymphoblastic leukemia cells [J]. Blood 1995; 85(10)2817–2828
- Fu Q., Kim S. W., Chen H. X., Grill S., Cheng Y. C. Degradation of topoisomerase I induced by topoisomerase I inhibitors is dependent on inhibitor structure but independent of cell death [J]. Molecular Pharmacology 1999; 55(4)677–683
- Keshelava N., Groshen S., Reynolds C. P. Cross-resistance of topoisomerase I and II inhibitors in neuroblastoma cell lines [J]. Cancer Chemother. Pharmacol. 2000; 45(1)1–8
- Silber R., Degar B., Costin D., Newcomb E. W., Mani M., Rosenberg C. R., Morse L., Drygas J. C., Canellakis Z. N., Potmesil M. Chemosensitivity of lymphocytes from patients with B-cell chrsonic lymphocytic leukemia to chlorambucil, fludarabine, and camptothecin analogs [J]. Blood 1994; 84(10)3440–3446
- Mitsui I., Kumazawa E., Hirota Y., Aonuma M., Sugimori M., Ohsuki S., Uoto K., Ejima A., Terasawa H., Sato K. A new water-soluble camptothecin derivative Dx-8951f exhibits potent antitumor activity against human tumors in vitro and in vivo [J]. Jpn J Cancer Res 1995; 86(8)776–782
- Plumb J. A., Milroy R., Kaye S. B. Effects of the PH dependence of 3-(4,5-dimethyl-2-yl)-2,5-diphenyl-tetrazolium-bromide-formazan adsorption on chemosensitivity determined by a novel tetrazolium-based assay [J]. Cancer Res. 1989; 49(16)4435–4440
- Takehara T., Liu X., Fujimoto J., Friedman S. L., Takahashi H. Expression and role of Bcl-xL in human hepatocellular carcinomas [J]. Hepatology. 2001; 34(1)55–61
- Emanuele S., Calvaruso G., Lauricella M., Giuliano M., Bellavia G., D'Anneo A., Vento R., Tesoriere G. Apoptosis induced in hepatoblastoma HepG2 cells by the proteasome inhibitor MG132 is associated with hydrogen peroxide production, expression of Bcl-XS and activation of caspase-3 [J]. Int. J. Oncol. 2002; 21(4)857–65
- Kim H., Rafiuddin-Shah M., Tu H. C., Jeffers J. R., Zambetti G. P., Hsieh J. J., Cheng E. H. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies [J]. Nat. Cell. Biol. 2006; 8(12)1348–58
- Lazou A., Iliodromitis E. K., Cieslak D., Voskarides K., Mousikos S., Bofilis E., Kremastinos D. T. Ischemic but not mechanical preconditioning attenuates ischemia/reperfusion induced myocardial apoptosis in anaesthetized rabbits: The role of Bcl-2 family proteins and ERK1/2 [J]. Apoptosis. 2006; 11(12)2195–204
- Luo D., Cheng S. C., Xie H., Xie Y. Effects of Bcl-2 and Bcl-XL protein levels on chemoresistance of hepatoblastoma HepG2 cell line [J]. Biochem. Cell. Biol. 2000; 78(2)119–26
- Li W., Sanki A., Karim R. Z., Thompson J. F., Soon Lee C., Zhuang L., McCarthy S. W., Scolyer R. A. The role of cell cycle regulatory proteins in the pathogenesis of melanoma [J]. Pathology. 2006; 38(4)287–301