177
Views
16
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLESCellular and Molecular Biology

Expression of CD147 Mediates Tumor Cells Invasion and Multidrug Resistance in Hepatocellular Carcinoma

, , , , &
Pages 977-983 | Published online: 11 Jun 2009

REFERENCES

  • Kerbel R., Korczak S., Lagarde B. A. Growth dominance of the metastatic cancer cell: cellular and molecular aspects. Adv Cancer Res 1990; 5: 87–132
  • Su Z. Z., Austin V. N., Zimmer S. G., Fisher P. B. Defining the critical gene expression changes associated with expression and suppression of the tumorigenic and metastatic phenotype in Ha-ras-transformed cloned rat embryo fibroblast cells. Oncogene 1993; 8: 1211–1219
  • Yang J. M., Xu Z., Wu H., Zhu H., Wu X., Hait W. N. Overexpression of extracellular matrix metalloproteinase inducer in multidrug resistant cancer cells. Mol Cancer Res 2003; 1: 420–427
  • Zou W., Zhu H., Wu X. Inhibition of CD147 gene expression via RNA interference reduces tumor cell invasion, tumorigenicity and increases chemosensitivity to paclitaxel in HO-8910pm cells. Cancer Lett 2006; 248: 211–218
  • Li Q. Q., Wang W. J., Xu J. D., Cao X. X., Chen Q., Yang J. M., Xu Z. D. Involvement of CD147 in regulation of multidrug resistance to P-gp substrate drugs and in vitro invasion in breast cancer cells. Cancer Sci 2007; 98: 1064–1069
  • Nelson A. R., Fingleton B., Rothenberg M. L., Matrisian L. M. Matrix metalloproteinases: biologic activity and clinical implications. J Clin Oncol 2000; 18: 1135–1149
  • Illemann M., Bird N., Majeed A., Sehested M., Laerum O. D., Lund L. R., Dano K., Nielsen B. S. MMP-9 is differentially expressed in primary human colorectal adenocarcinomas and their metastases. Mol Cancer Res 2006; 4: 293–302
  • Rio M. C. From a unique cell to metastasis is a long way to go: clues to stromelysin-3 participation. Biochimie 2005; 87: 299–306
  • Chan H. S., Thorner P. S., Haddad G., Ling V. Immunohistochemical detection of P-glycoprotein: prognostic correlation in soft tissue sarcoma of childhood. J Clin Oncol 1990; 8: 689–704
  • Verrelle P., Meissonnier F., Fonck Y., Feillel V., Dionet C., Kwiatkowski F., Plagne R., Chassagne J. Clinical relevance of immunohistochemical detection of multidrug resistance P-glycoprotein in breast carcinoma. J Natl Cancer Inst 1991; 83: 111–116
  • Yang J. M., Yang G. Y., Medina D. J., Vassil A. D., Liao J., Hait W. N. Treatment of multidrug resistant (MDR1) murine leukemia with P-glycoprotein substrates accelerates the course of the disease. BBRC 1999; 266: 167–173
  • Weinstein R. S., Jakate S. M., Dominguez J. M., Lebovitz M. D., Koukoulis G. K., Kuszak J. R., Klusens L. F., Grogan T. M., Saclarides T. J., Roninson I. B., Coon J. S. Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis. Cancer Res 1991; 51: 2720–2726
  • Ding S., Chamberlain M., McLaren A., Goh L., Duncan I., Wolf C. R. Cross-talk between signalling pathways and the multidrug resistant protein MDR-1. Br J Cancer 2001; 85: 1175–1184
  • Davidson B., Givant-Horwitz V., Laranovici P., Risberg B., Nesland J. M., Trope C. G., Schaefer E., Reich R. Matrix rnetalloproteinases (MMP), EMMPRIN (extracellular matrix metalloproteinase inducer) and mitogen-activated protein kinases (MAPK): co-expression in metastatic serous ovarian carcinoma. Clin Exp Metastasis 2002; 20: 621–631
  • Lim M., Martinez T., Jablons D., Cameron R., Guo H., Toole B., Li J. D., Basbaum C. Tumor-derived EMMPRIN (extracellular matrix metalloproteinase inducer) stimulates collagenase transcription through MAPK p38. FEBS Lett 1998; 441: 88–92
  • Khunkeawla P., Moonsom S., Staffler G., Kongtawelert P., KasinrerK W. Engagement of CD147 molecule-induced cell aggregation through the activation of protein kinases and reorganization of the cytoskeleton. Immunobiol 2001; 203: 659–669
  • Jia L., Wang H., Qu S., Miao X., Zhang J. CD147 Regulates Vascular Endothelial Growth Factor-A Expression, Tumorigenicity, and Chemosensitivity to Curcumin in Hepatocellular Carcinoma. IUBMB Life 2008; 60: 57–63
  • Misra S., Ghatak S., Zoltan-Jones A., Toole B. P. Regulation of multidrug resistance in cancer cells by hyaluronan. J Biol Chem 2003; 278: 25285–25288
  • Muramatsu T., Miyauchi T. Basigin (CD147): a multifunctional transmembrane protein involved in reproduction, neural function, inflammation and tumor invasion. Histol Histopathol 2003; 18: 981–987
  • Yan L. S., Zucker B. P. Roles of the multifunctional glycoprotein, emmprin (basigin; CD147), in tumour progression. Thromb Haemos 2005; 93: 199–204
  • Kanekura T., Chen X., Kanzaki T. Basigin (CD147) is system with an improved hairpin and its significant expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts. Int J Cancer 2002; 99: 520–528
  • Basset P., Bellocq J. P., Wolf C., Stoll I., Hutin P., Limacher J. M., Podhajcer O. L., Chenard M. P., Rio M. C., Chambon P. A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas. Nature 1990; 348: 699–704
  • Delebecq T. J., Porte H., Zerimech F., Copin M. C., Dacquembronne V., Gouyer E. Overexpression level of stromelysin 3 is related to the lymph node involvement in nonsmall cell lung cancer. Clin Cancer Res 2000; 6: 1086–1092
  • Deng H., Guo R. F., Li W. M., Zhao M., Lu Y. Y. Matrix metalloproteinase 11 depletion inhibits cell proliferation in gastric cancer cells. BBRC 2005; 14: 274–281
  • Noel A., Boulay A., Kebers F., Kannan R., Hajitou A., CalbergBacq C. M. Demonstration in vivo that stromelysin-3 functions through its proteolytic activity. Oncogene 2000; 19: 1605–1612
  • Sameshima T., Nabeshima K., Toole B. P., Yokogami K., Okada Y., Goya T., Koono M., Wakisaka S. Glioma cell extracellular matrix metalloproteinase inducer (EMMPRIN) (CD147) stimulates production of membranetype matrix metalloproteinases and activated gelatinase A in co-cultures with brain-derived fibroblasts. Cancer Lett 2000; 157: 177–184
  • Jiang J. L., Zhou Q., Yu M. K., Ho L. S., Chen Z. N., Chan H. C. The involvement of HAb18G/CD147 in regulation of store-operated calcium entry and metastasis of human hepatoma cells. J Biol Chem 2001; 276: 46870–46877
  • Jia L., Cao J., Wei W., Wang S., Zuo Y., Zhang J. CD147 depletion down-regulates matrix metalloproteinase-11, vascular endothelial growth factor-A expression and the lymphatic metastasis potential of murine Hepatocarcinoma Hca-F. IJBCB 2007; 39: 2135–2142
  • Osborn M. T., Chambers T. C. Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to Adriamycin and other chemotherapeutic drugs. J Biol Chem 1996; 271: 30950–30955
  • Yang J. M., Vassil A. D., Hait W. N. Activation of phospholipase C induces the expression of the multidrug resistance (MDR1) gene through the Raf-MAPK pathway. Mol Pharmacol 2001; 60: 674–680
  • Huang C., Jacobson K., Schaller M. D. MAP kinases and cell mobility. J Cell Sci 2004; 117: 4619–4628
  • Brauchle M., Gluck D., Padova F. D., Han J. H., Gram H. Independent role of p38 and ERK1/2 mitogen-activated kinases in the upregulation of matrix metalloproteinase-1. Exp Cell Res 2000; 258: 135–144
  • Xu H. Y., Qian A. R., Shang P., Xu J., Kong L. M., Bian H. J., Chen Z. N. siRNA targeted against HAb18G/CD147 inhibits MMP-2 secretion, actin and FAK expression in hepatocellular carcinoma cell line via ERK1/2 pathway. Cancer Lett 2007; 18: 336–344
  • Gabison E. E., Hoang-Xuan T., Mauviel A. Menasshi, S. EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair. Biochimie 2005; 87: 361–368

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.