BONE MARROW TRANSPLANTATION OR HYDROXYUREA FOR SICKLE CELL ANEMIA: Long-Term Effects on Semen Variables and Hormone Profiles

REFERENCES

• Quinn C T, Rogers Z R, Buchanan G R. Survival of children with sickle cell disease. Blood. 2004; 103: 4023–4027
   PubMed Web of Science ®Google Scholar
• Hankins J S, Ware R E, Rogers Z R, et al. Long-term hydroxyurea therapy for infants with sickle cell anemia: the HUSOFT extension study. Blood. 2005; 106: 2269–2275
   PubMed Web of Science ®Google Scholar
• Walters M C, Storb R, Patience M, et al. Impact of bone marrow transplantation for symptomatic sickle cell disease: an interim report. Blood. 2000; 95: 1918–1924
   PubMed Web of Science ®Google Scholar
• Mehta S R, Afenyi-Annan A, Byrns P J, et al. Opportunities to improve outcomes in sickle cell disease. Am Fam Physician. 2006; 74: 303–310
   PubMed Web of Science ®Google Scholar
• Rogers Z R, Buchanan G R. Expanding the role of hydroxyurea in children with sickle cell disease. J Pediatr. 2004; 145: 287–288
   Google Scholar
• Zimmerman S A, Schultz W H, Davis J S, et al. Sustained long-term hematologic efficacy of hydroxyurea at maximum tolerated dose in children with sickle cell disease. Blood. 2004; 103: 2039–2045
   PubMed Web of Science ®Google Scholar
• De Montalambert M, Brousse V, Elie C, et al. Long-term hydroxyurea treatment in children with sickle cell disease: tolerance and clinical outcomes. Haematologica. 2006; 91: 125–128
   Google Scholar
• Garozzo G, Disca S, Fidone C, et al. Azoospermia in a patient with sickle cell disease treated by hydroxyurea. Hematologica. 2000; 85: 1216–1218
   PubMed Web of Science ®Google Scholar
• Masood J, Hafeez A, Hughes A, et al. Hydroxyurea therapy: a rare cause of reversible azoospermia. Int Urol Nephrol. 2007; 39: 905–907
   PubMedGoogle Scholar
• Grigg A. Effect of hydroxyurea on sperm count, motility and morphology in adult men with sickle cell or myeloproliferative disease. Inter Med J. 2007; 37: 190–192
   Google Scholar
• Vermylen C. Hematopoietic stem cell transplantation in sickle cell disease. Blood Rev. 2003; 17: 163–166
   Google Scholar
• Eggleston B, Patience M, Edwards S, et al. Multicenter Study of HCT for SCA. Effect of myeloablative bone marrow transplantation on growth in children with sickle cell anaemia: results of the multicenter study of haematopoietic cell transplantation for sickle cell anaemia. Br J Haematol. 2007; 136: 673–676
   PubMed Web of Science ®Google Scholar
• Anserini P, Chiodi S, Spinelli S, et al. Semen analysis following allogeneic bone marrow transplantation: additional data for evidence-based counselling. Bone Marrow Transplant. 2002; 30: 447–451
   PubMed Web of Science ®Google Scholar
• Brachet C, Heinrichs C, Tenoutasse S, et al. Children with sickle cell disease: growth and gonadal function after hematopoietic stem cell transplantation. J Pediatr Hematol Oncol. 2007; 29: 445–450
   PubMed Web of Science ®Google Scholar
• Agbaraji V O, Scott R B, Leto S, et al. Fertility studies in sickle cell disease: semen analysis in adult male patients. Int J Fertil. 1988; 33: 347–352
   PubMedGoogle Scholar
• Osegbe D N, Akinyanju O, Amaku E O. Fertility in males with sickle cell disease. Lancet. 1981; 2: 275–276
   PubMed Web of Science ®Google Scholar
• Nahoum C R, Fontes E A, Freire F R. Semen analysis in sickle cell disease. Andrologia. 1980; 12: 542–545
   PubMedGoogle Scholar
• Modebe O, Ezeh U O. Effect of age on testicular function in adult males with sickle cell anemia. Fertil Steril. 1995; 63: 907–912
   Google Scholar
• Osegbe D N, Akinyanju O. Testicular dysfunction in men with sickle cell disease. Postgrad Med J 1987; 63: 95–98
   PubMed Web of Science ®Google Scholar
• Parshad O, Stevens M C, Preece M A, et al. The mechanism of low testosterone levels in homozygous sickle-cell disease. West Indian Med J. 1994; 43: 12–14
   PubMed Web of Science ®Google Scholar
• Li M, Forgarty J, Whitney K D, et al. Repeated testicular infarction in a patient with sickle cell disease: a possible mechanism for testicular failure. Urology. 2003; 62: 551xi–551xiv
   Google Scholar
• Rowe P J, Comhaire F H, Harcreave T B, et al. WHO manual for the standardized investigation, diagnosis and management of the infertile male. Cambridge University Press, New York 2000
   Google Scholar
• Kruger T F, Swanson R J, Hamilton M, et al. Abnormal sperm morphology and other semen parameters related to the outcome of the hamster oocyte human sperm penetration assay. Int J Androl. 1988; 11: 107–113
   Google Scholar
• Bujan L, Mieusset R, Mansat A, et al. Testicular size in infertile men: relationship to semen characteristics and hormonal blood levels. Br J Urol. 1989; 64: 632–637
   Google Scholar
• Arai T, Kitahara S, Horiuchi, et al. Relationship of testicular volume to semen profiles and serum hormone concentrations in infertile Japanese males. Int J Fertil Womens Med. 1998; 43: 40–47
   PubMedGoogle Scholar
• Evenson D P, Jost L K. Hydroxyurea exposure alters mouse testicular kinetics and sperm chromatin structure. Cell Prolif. 1993; 26: 147–159
   PubMed Web of Science ®Google Scholar
• Bernaudin F, Socie G, Kuentz M, et al. SFGM-TC. Long-term results of related myeloablative stem cell transplantation to cure sickle cell disease. Blood. 2007; 110: 2749–2756
   PubMed Web of Science ®Google Scholar
• Grosskreutz C, Scigliano E, Osman K, et al. Graft versus host disease after stem cell allotransplantation with low dose total body irradiation, fludarabine, and antithymocyte globulin. Transplant. 2007; 84: 598–604
   Google Scholar
• Brachet C, Azzi N, Demulder A, et al. Hydroxyurea treatment for sickle cell disease: impact on haematopoietic stem cell transplantation's outcome. Bone Marrow Transplant. 2004; 33: 799–803
   PubMed Web of Science ®Google Scholar
• Wyns C, Curaba M, Martinez-Madrid B, et al. Spermatogonial survival after cryopreservation and short-term orthotopic immature human cryptorchid testicular tissue grafting to immunodeficient mice. Hum Reprod. 2007; 22: 1603–1611
   PubMed Web of Science ®Google Scholar
• Keros V, Hultenby K, Borgstrom B, et al. Methods of cryopreservation of testicular tissue with viable spermatogonia in pre-pubertal boys undergoing gonadotoxic cancer treatment. Hum Reprod. 2007; 22: 1384–1395
   PubMed Web of Science ®Google Scholar