Molecular characterization, physicochemical properties, known and potential applications of phytases: An overview

References

• Anderson G. 1980. Assessing organic phosphorus in soils. In Khasawneh FE, Sample EC, Kamprath EJ (eds), The Role of Phosphorus in Agriculture (pp. 411–431 ). Madison, WI: American Society of Agronomy.
   Google Scholar
• Asmar F. 1997. Variation in activity of root extracellular phytase between genotypes of barley. Plant Soil 195:61–64.
   Web of Science ®Google Scholar
• Baldi BG, Scott JJ, Everard JD, Loewus FA. 1988. Localization of constitutive phytases in lily pollen and properties of pH 8 form. Plant Sci 56:137–147.
   Web of Science ®Google Scholar
• Baruah K, Pal AK, Sahu NP, Jain KK, Mukherjee SC, Debnath D. 2005. Dietary protein level, microbial phytase, citric acid and their interactions on bone mineralization of Labeo rohita (Hamilton) juveniles. Aquacult Res 36:803–812.
   Web of Science ®Google Scholar
• Baruah K, Sahu NP, Pal AK, Debnath D, Yengkokpam S, Mukherjee SC. 2007. Interactions of dietary microbial phytase, citric acid and crude protein level on mineral utilization by Rohu, Labeo rohita (Hamilton), juveniles. J World Aquacult Soc 38:238–249.
   Web of Science ®Google Scholar
• Bebot-Brigaud A, Dange C, Fauconnier N, Gerard C. 1999. 31P NMR, potentiometric and spectrophotometric studies of phytic acid ionization and complexation properties toward Co2+, Ni2+, Cu2+, Zn2+ and Cd2+. J Inorg Biochem 75:71–78.
   Web of Science ®Google Scholar
• Berka RM, Rey MW, Brown KM, Byun T, Klotz AV. 1998. Molecular characterization and expression of a phytase gene from the thermophilic fungus Thermomyces lanuginosus. Appl Environ Microbiol 64:4423–4427.
   PubMed Web of Science ®Google Scholar
• Berridge MJ, Irvine RF. 1984. Inositol triphosphate, a novel second messenger in cellular signal transduction. Nature 312:315–321.
   PubMed Web of Science ®Google Scholar
• Bregitzer PP, Raboy V. 2006. Effects of four independent low-phytate mutations on barley (Hordeum vulgare L.) agronomic performance. Crop Sci 46:1318–1322.
   Web of Science ®Google Scholar
• Brinch-Pedersen H, Hatzack F, Sorensen LD, Holm PB. 2003. Concerted action of endogenous and heterologous phytase on phytic acid degradation in seed of transgenic wheat (Triticum aestivum L). Trans Res 12:649–659.
   PubMed Web of Science ®Google Scholar
• Brinch-Pedersen H, Frank H, Eva S, Elsa A, Katrine P, Preben BH. 2006. Heat-stable phytases in transgenic wheat (Triticum aestivum L.): deposition pattern, thermostability, and phytate hydrolysis. J Agric Food Chem 54:4624–4632.
   PubMed Web of Science ®Google Scholar
• Camden BJ, Morel PCH, Thomas DV, Ravindran V, Bedford MR. 2001. Effectiveness of exogenous microbial phytase in improving the bioavailabilities of phosphorus and other nutrients in maize-soya-bean meal diets for broilers. Anim Sci 73:289–297.
   Google Scholar
• Carrington AL, Calcutt NA, Ettlinger CB, Gustafsson T, Tomlinson DR. 1993. Effects of treatment with myo-inositol or its 1,2,6-triphosphate (PP56) on nerve conduction in streptozotocin-diabetes. Eur J Pharmacol 237:257–263.
   PubMed Web of Science ®Google Scholar
• Casey A, Walsh G. 2003. Purification and characterization of extracellular phytase from Aspergillus niger ATCC 9142. Bioresour Technol 86:183–188.
   PubMed Web of Science ®Google Scholar
• Chadha BS, Harmeet G, Mandeep M, Saini HS, Singh N. 2004. Phytase production by the thermophilic fungus Rhizomucor pusillus. World J Microbiol Biotechnol 20:105–109.
   Web of Science ®Google Scholar
• Chauynarong N, Iji PA, Isariyodom S, Mikkelsen L. 2008. The influence of an exogenous microbial enzyme supplement on feed consumption, body growth and follicular development of pre-lay pullets on maize-soy diets. Int J Poult Sci 7:57–262.
   Google Scholar
• Chiera JM, Finer JJ, Grabau EA. 2004. Ectopic expression of a soybean phytase in developing seeds of Glycine max to improve phosphorus availability. Plant Mol Biol 56:895–904.
   PubMed Web of Science ®Google Scholar
• Cho J, Lee C, Kang S, Lee J, Lee H, Bok J, Woo J, Moon Y, Choi Y. 2005. Molecular cloning of a phytase gene (phy M) from Pseudomonas syringae MOK1. Curr Microbiol 51:11–15.
   PubMed Web of Science ®Google Scholar
• Choi YM, Suh HJ, Kim JM. 2001. Purification and properties of extracellular phytase from Bacillus sp. KHU-10. J Protein Chem 20:287–292.
   PubMedGoogle Scholar
• Chu HM, Guo RT, Lin TW, Chou CC, Shr HL, Lai HL, Tang TY, Cheng KJ, Selinger BL, Wang AHJ. 2004. Structures of Selenomonas ruminantium phytase in complex with persulfated phytate: DSP phytase fold and mechanism for sequential substrate hydrolysis. Structure 12:2015–2024.
   PubMed Web of Science ®Google Scholar
• Claxon A, Morris C, Blake D, Siren M, Halliwell B, Gustafsson T, Lofkvist B, Bergelin I. 1990. The anti-inflammatory effects of D-myo-inositol-1,2,6-triphosphate (PP56) on animal models of inflammation. Agents Actions 29:68–70.
   PubMedGoogle Scholar
• Common FH. 1989. Biological availability of phosphorus for pigs. Nature 143:370–380.
   Google Scholar
• Cosgrove DJ. 1970. Inositol phosphate phosphatases of microbial origin. Inositol phosphate intermediates in the dephosphorylation of the hexaphosphates of myo-inositol, scyllo-inositol, and D-chiro-inositol by a bacterial (Pseudomonas sp.) phytase. Austral J Biol Sci 23:1207–1220.
   PubMedGoogle Scholar
• Costello AJR, Glonek T, Myers TC. 1976. 31P nuclear magnetic resonance-pH titrations of myo-inositol hexaphosphate. Carbohydr Res 46:159–171.
   PubMed Web of Science ®Google Scholar
• Cowieson AJ, Acamovic T, Bedford MR. 2006. Phytic acid and phytase: implications for protein utilization by poultry. Poult Sci 85:878–885.
   PubMed Web of Science ®Google Scholar
• Cromwell GL, Coffey RD, Parker GR, Monegue HJ, Randolph JH. 1995a. Efficacy of a recombinant-derived phytase in improving the bioavailability of phosphorus in corn-soybean meal diets for pigs. J Anim Sci 73:2000–2008.
   PubMed Web of Science ®Google Scholar
• Cromwell GL, Coffey RD, Monegue HJ, Randolph JH. 1995b. Efficacy of low-activity, microbial phytase in improving the bioavailability of phosphorus in corn-soybean meal diets for pigs. J Anim Sci 73:449–456.
   PubMed Web of Science ®Google Scholar
• Dasgupta S, Dasgupta D, Sen M, Biswas S, Biswas BB. 1996. Interaction of myoinositol triphosphate-phytase complex with the receptor for intracellular Ca2+ mobilization in plants. Biochemistry 35:4994–5001.
   PubMed Web of Science ®Google Scholar
• De Angelis M, Gallo G, Corbo MR, McSweeney PLH, Faccia M, Giovine M, Gobbetti M. 2003. Phytase activity in sourdough lactic acid bacteria: purification of a phytase from Lactobacillus sanfranciscensis CB1. Int J Food Microbiol 87:259–270.
   PubMed Web of Science ®Google Scholar
• de Boland AR, Garner GB, O’Dell BL. 1975. Identification and properties of “Phytate” in cereal grains and oilseed products. J Agric Food Chem 23:1186–1189.
   PubMed Web of Science ®Google Scholar
• Debnath D, Pal AK, Sahu NP, Jain KK, Yengkokpam S, Mukherjee SC. 2005. Effect of dietary microbial phytase supplementation on growth and nutrient digestibility of Pangasius pangasius (Hamilton) fingerlings. Aquacult Res 36:180–187.
   Web of Science ®Google Scholar
• Denbow DM, Grabau EA, Lacy GH, Kornegay ET, Russell DR, Umbeck PF. 1998. Soybeans transformed with a fungal phytase gene improve phosphorus availability for broilers.
   Google Scholar
• Dilger RN, Onyango EM, Sands JS, Adeola O. 2004. Evaluation of microbial phytase in broiler diets. Poult Sci 83:962–970.
   PubMed Web of Science ®Google Scholar
• Dionisio G, Holm PB, Brinch-Pendersen H. 2007. Wheat (Triticum aestivum L.) and barley (Hordeum vulgare L.) multiple inositol polyphosphate phosphatases (MINPPs) are phytases expressed during grain filling and germination. Plant Biotechnol J 5:325–338.
   PubMed Web of Science ®Google Scholar
• Drakakaki G, Marcel S, Glahn RP, Lund EK, Pariagh S, Fischer R, Christou P, Stoger E. 2005. Endosperm-specific co-expression of recombinant soybean ferritin and Aspergillus phytase in maize results in significant increases in the levels of bioavailable iron. Plant Mol Biol 59:869–880.
   PubMed Web of Science ®Google Scholar
• Ebrahimnezhad Y, Shivazad M, Taherkhani R, Nazeradl K. 2008. Effects of ethylenediaminetetraacetic acid on phytate phosphorus utilization and efficiency of microbial phytase in broiler chicks. J Anim Physiol Anim Nutr 92:168–172.
   PubMed Web of Science ®Google Scholar
• Elkhalil EAI, Männer K, Borriss R, Simon O. 2007. In vitro and in vivo characteristics of bacterial phytases and their efficacy in broiler chickens. Br Poult Sci 48:64–70.
   PubMed Web of Science ®Google Scholar
• Ellestad LE, Angel R, Soares JH Jr. 2002. Intestinal phytase I: Detection and preliminary characterization of activity in the intestinal brush border membrane of hybrid striped bass Morone saxatilis × M. chrysops. Fish Physiol Biochem 26:249–258.
   Web of Science ®Google Scholar
• Forsberg CW, Phillips JP, Golovan SP, Fan MZ, Meidinger RG, Ajakaiye A, Hilborn D, Hacker RR. 2003. The Enviropig physiology, performance, and contribution to nutrient management advances in a regulated environment: the leading edge of change in the pork industry. J Anim Sci 81:E68–E77.
   PubMed Web of Science ®Google Scholar
• Fritts CA, Waldroup PW. 2006. Modified phosphorus program for broilers based on commercial feeding intervals to sustain live performance and reduce total and water-soluble phosphorus in litter. J Appl Poult Res 15:207–218.
   Web of Science ®Google Scholar
• Garrett JB, Kretz KA, O’Donoghue E, Kerovuo J, Kim W, Barton, NR., Hazelwood GP, Short JM, Robertson DE, Gray KA. 2004. Enhancing the thermal tolerance and gastric performance of a microbial phytase for use as a phosphate-mobilizing monogastric-feed supplement. Appl Environ Microbiol 70:3041–3046.
   PubMed Web of Science ®Google Scholar
• George TS, Richardson AE, Hadobas PA, Simpson RJ. 2004. Characterization of transgenic Trifolium subterraneum L. which expresses phyA and releases extracellular phytase: growth and P nutrition in laboratory media and soil. Plant Cell Environ 27:1351–1361.
   Web of Science ®Google Scholar
• George TS, Richardson AE, Smith JB, Hadobas PA, Simpson RJ. 2005a. Limitations to the potential of transgenic Trifolium subterraneum L. plants that exude phytase when grown in soils with a range of organic P content. Plant Soil 258:263–274.
   Web of Science ®Google Scholar
• George TS, Simpson RJ, Hadobas PA, Richardson AE. 2005b. Expression of a fungal phytase gene in Nicotiana tabacum improves phosphorus nutrition of plants grown in amended soils. Plant Biotech J 3:129–140.
   PubMed Web of Science ®Google Scholar
• Golovan S, Wang G, Zhang J, Forsberg CW. 2000. Characterization and overproduction of the Escherichia coli appA encoded bifunctional enzyme that exhibits both phytase and acid phosphatase activities. Can J Microbiol 46:59–71.
   PubMed Web of Science ®Google Scholar
• Golovan SP, Hayes MA, Phillips JP, Forsberg CW. 2001a. Transgenic mice expressing bacterial phytase as a model for phosphorus pollution control. Nat Biotechnol 19:429–433.
   PubMed Web of Science ®Google Scholar
• Golovan SP, Meidinger RG, Ajakaiye A, Cottrill M, Wiederkehr MZ, Barney DJ, Plante C, Pollard JW, Fan MZ, Hayes MA, Laursen J, Hjorth JP, Hacker RR, Phillips JP, Forsberg CW. 2001b. Pigs expressing salivary phytase produce low-phosphorus manure. Nat Biotechnol 19:741–745.
   PubMed Web of Science ®Google Scholar
• Gordon RW, Roland DA Sr. 1998. Influence of supplemental phytase on calcium and phosphorus utilization in laying hens. Poult Sci 77:290–294.
   PubMed Web of Science ®Google Scholar
• Grases F, March JG, Prieto RM, Simonet BM, Costa-Bauza A, Garcia-Raja A, Conte A. 2000. Urinary phytate in calcium oxalate stone formers and healthy people: dietary effects on phytate excretion. Scand J Urol Nephrol 34:162–164.
   PubMed Web of Science ®Google Scholar
• Greiner R. 2004. Purification and properties of a phytate-degrading enzyme from Pantoea agglomerans. Protein J 23:567–576.
   PubMed Web of Science ®Google Scholar
• Greiner R, Konietzny U. 1998. Endogenous phytate-degrading enzymes are responsible for phytate reduction while preparing beans (Phaseolus vulgaris). J Food Process Preserv 29:321–331.
   Google Scholar
• Greiner R, Konietzny U. 1999. Improving enzymatic reduction of myo-inositol phosphates with inhibitory effects on mineral absorption in black beans (Phaseolus vulgaris var. Preto). J Food Process Preserv 23:249–261.
   Web of Science ®Google Scholar
• Greiner R, Konietzny U. 2006. Phytase for food application. Food Technol Biotechnol 44:125–140.
   Web of Science ®Google Scholar
• Greiner R, Kontietzny U, Jany KD. 1993. Purification and characterization of two phytases from Escherichia coli. Arch Biochem Biophys 303:107–113.
   PubMed Web of Science ®Google Scholar
• Greiner R, Kontietzny U, Jany KD. 1997. Purification and properties of a phytase from rye. J Food Chem 22:143–161.
   Google Scholar
• Gulati HK, Chadha BS, Saini HS. 2007. Production and characterization of thermostable alkaline phytase from Bacillus laevolacticus isolated from rhizosphere soil. J Ind Microbiol Biotechnol 34:91–98.
   PubMed Web of Science ®Google Scholar
• Ha NC, Oh BC, Shin S, Kim HJ, Oh TK, Kim YO, Choi KY, Oh BH. 2000. Crystal structures of a novel, thermostable phytase in partially and fully calcium-loaded states. Nat Struct Biol 7:147–153.
   PubMedGoogle Scholar
• Haefner S, Knietsch A, Scholten E, Braun J, Lohscheidt M, Zelder O. 2005. Biotechnological production and applications of phytases. Appl Microbiol Biotechnol 68:588–597.
   PubMed Web of Science ®Google Scholar
• Hamada A, Yamaguchi KI, Ohnishi N, Harada M, Nikumaru S, Honda H. 2005. High-level production of yeast (Schwanniomyces occidentalis) phytase in transgenic rice plants by a combination of signal sequence and codon modification of the phytase gene. Plant Biotechnol J 3:43–55.
   PubMed Web of Science ®Google Scholar
• Hamada JS. 1996. Isolation and identification of the multiple forms of soybean phytases. J Am Oil Chem Soc 73:1143–1151.
   Web of Science ®Google Scholar
• Han Y, Lei XG. 1999. Role of glycosylation in the functional expression of an Aspergillus niger phytase (phyA) in Pichia pastoris. Arch Biochem Biophys 364:83–90.
   PubMed Web of Science ®Google Scholar
• Han Y, Wilson DB, Lei XG. 1999. Expression of an Aspergillus niger phytase gene (phy A) in Saccharomyces cerevisiae. Appl Environ Microbiol 65:1915–1918.
   PubMed Web of Science ®Google Scholar
• Hara A, Ebina S, Kendo A, Funaguma T. 1985. A new type of phytase from pollen of Typha latifolia L. Agric Biol Chem 49: 3539–3544.
   Web of Science ®Google Scholar
• Harland BF, Oberleas D. 1999. Phytic acid complex in feed ingredients. In Coelho MB, Kornegay ET (eds), Phytase in Animal Nutrition and Waste Management (2nd rev. edn, pp. 69–76 ). Mexico: BASF.
   Google Scholar
• Haros M, Rosell CM, Benedito C. 2001. Fungal phytase as a potential breadmaking additive. Eur Food Res Technol 213:317–322.
   Web of Science ®Google Scholar
• Harrison AT. 1987. Soil Organic Phosphorus. A Review of World Literature. Wallingford, UK: CAB International.
   Google Scholar
• Hayes JE, Simpson RJ, Richardson AE. 2000. The growth and phosphorus utilization of plants in sterile media when supplied with inositol hexaphosphate, glucose-1-phosphate or inorganic phosphate. Plant Soil 220:165–174.
   Web of Science ®Google Scholar
• Hegeman CE, Grabau EA. 2001. A novel phytase with sequence similarity to purple acid phosphatases is expressed in cotyledons of germinating soybean seedlings. Plant Physiol 126:1598–1608.
   PubMed Web of Science ®Google Scholar
• Herter T, Berezina OV, Zinin NV, Velikodvorskaya GA, Greiner R, Borriss R. 2006. Glucose-1-phosphatase (AgpE) from Enterobacter cloacae displays enhanced phytase activity. Appl Microbiol Biotechnol 70:60–64.
   PubMed Web of Science ®Google Scholar
• Hong CY, Cheng KJ, Tseng TH, Wang CS, Liu LF, Yu SM. 2004. Production of two highly active bacterial phytases with broad pH optima in germinated transgenic rice seeds. Trans Res 13:29–39.
   PubMed Web of Science ®Google Scholar
• Htoo JK, Sauer WC, Yáñez JL, Cervantes M, Zhang Y, Helm JH, Zijlstra RT. 2007. Effect of low-phytate barley or phytase supplementation to a barley-soybean meal diet on phosphorus retention and excretion by grower pigs. J Anim Sci 85:2941–2948.
   PubMed Web of Science ®Google Scholar
• Huang H, Luo H, Yang P, Meng K, Wang Y, Yuan, T, Bai Y, Yao B. 2006. A novel phytase with preferable characteristics from Yersinia intermedia. Biochem Biophys Res Commun 350:884–889.
   PubMed Web of Science ®Google Scholar
• Hubel F, Beck E. 1996. Maize root phytase. Purification, characterization and localization of enzyme activity and its putative substrate. Plant Physiol 112:1429–1436.
   PubMed Web of Science ®Google Scholar
• Hurrell RF, Reddy MB, Juillerat MA, Cook JD. 2003. Degradation of phytic acid in cereal porridges improves iron absorption by human subjects. Am J Clin Nutr 77:1213–1219.
   PubMed Web of Science ®Google Scholar
• Idriss EE, Makarewicz O, Farouk A, Rosner K, Greiner R, Bochow H, Richter T, Borriss R. 2002. Extracellular phytase activity of Bacillus amyloliquefaciens FZB45 contributes to its plant-growth-promoting effect. Microbiology 148:2097–2109.
   PubMed Web of Science ®Google Scholar
• Iqbal TH, Lewis KO, Cooper BT. 1994. Phytase activity in the human and rat small intestine. Gut 35:1233–1236.
   PubMed Web of Science ®Google Scholar
• IUPAC–IUB. 1968. Eur J Biochem 5:1.
   PubMedGoogle Scholar
• Jang DA, Fadel JG, Klasing KC, Mireles AJ, Ernst RA, Young KA, Cook A, Raboy V. 2003. Evaluation of low-phytate corn and barley on broiler chick performance. Poult Sci 82:1914–1924.
   PubMed Web of Science ®Google Scholar
• Jareonkitmongkol S, Ohya M, Watanabe R, Takagi H, Nakamori S. 1997. Partial purification of phytase from a soil isolate bacterium, Klebsiella oxytoca MO-3. J Ferment Bioeng 83:393–394.
   Google Scholar
• Jariwalla RJ, Sabin R, Lawson S, Herman ZS. 1990. Lowering of serum cholesterol and triglycerides and modulation of divalent cations by dietary phytate. J Appl Nutr 42:18–28.
   Google Scholar
• Kaur P, Kunze G, Satyanarayana T. 2007. Yeast phytases: present scenario and future perspectives. Crit Rev Biotechnol 27:93–109.
   PubMed Web of Science ®Google Scholar
• Kerovuo J, Lauraeus M, Nurminen P, Kalkkinen N, Apajalahti J. 1998. Isolation, characterization, molecular gene cloning, and sequencing of a novel phytase from Bacillus subtilis. Appl Environ Microbiol 64: 2079–2085.
   PubMed Web of Science ®Google Scholar
• Kerovuo J, Rouvinen J, Hatzack F. 2000a. Analysis of myo-inositol hexakisphosphate hydrolysis by Bacillus phytase: indication of a novel reaction mechanism. Biochem J 352:623–628.
   PubMed Web of Science ®Google Scholar
• Kerovuo J, Lappalainen I, Reinikainen T. 2000b. The metal dependence of Bacillus subtilis phytase. Biochem Biophys Res Commun 268:365–369.
   PubMed Web of Science ®Google Scholar
• Kies AK, De Jonge LH, Kemme PA, Jongbloed AW. 2006. Interaction between protein, phytate, and microbial phytase. In vitro studies. J Agric Food Chem 54:1753–1758.
   PubMed Web of Science ®Google Scholar
• Kim YO, Kim HK, Bae KS, Yu JH, Oh TK. 1998a. Purification and properties of a thermostable phytase from Bacillus sp. DSII. Enz Microbial Technol 22:2–7.
   Web of Science ®Google Scholar
• Kim YO, Lee JK, Kim HK, Yu JH, Oh TK. 1998b. Cloning of the thermostable phytase gene (phy) from Bacillus sp. DS11 and its overexpression in Escherichia coli. FEMS Microbiol Lett 162: 185–191.
   PubMed Web of Science ®Google Scholar
• Kim YO, Lee JK, Oh BC, Oh TK. 1999. High-level expression of a recombinant thermostable phytase in Bacillus subtilis. Biosci Biotechnol Biochem 63: 2205–2207.
   PubMed Web of Science ®Google Scholar
• Kim YO, Kim HW, Lee JH, Kim KK, Lee SJ. 2006. Molecular cloning of the phytase gene from Citrobacter braakii and its expression in Saccharomyces cerevisiae. Biotechnol Lett 28: 33–38.
   PubMed Web of Science ®Google Scholar
• Konietzny U, Greiner R, Jany KD. 1995. Purification and characterization of a phytase from spelt. J Food Biochem 18:165–183.
   Web of Science ®Google Scholar
• Laboure AM, Gagnon J, Lescure AM. 1993. Purification and characterization of a phytase (myo-inositol hexakisphosphate phosphohydrolase) accumulated in maize (Zea mays) seedlings during germination. Biochem J 295:413–419.
   PubMed Web of Science ®Google Scholar
• Larsson M, Sandberg AS. 1995. Malting of oats in a pilot-plant process. Effects of heat treatment, storage and soaking conditions on phytate reduction. J Cereal Sci 21:87–95.
   Web of Science ®Google Scholar
• Lassen SF, Breinholt J, Ostergaard PR, Brugger R., Bischoff A, Wyss M, Fuglsang CC. 2001. Expression, gene cloning, and characterization of five novel phytases from four basidiomycete fungi: Peniophora lycii, Agrocybe pediades, a Ceriporia sp., and Trametes pubescens. Appl Environ Microbiol 67: 4701–4707.
   PubMed Web of Science ®Google Scholar
• Lee J, Choi Y, Lee PC, Kang S, Bok J, Cho J. 2007. Recombinant production of Penicillium oxalicum PJ3 phytase in Pichia pastoris. World J Microbiol Biotechnol 23:443–446.
   Web of Science ®Google Scholar
• Lee S, Kim T, Stahl CH, Lei XG. 2005. Expression of Escherichia coli AppA2 phytase in four yeast systems. Biotechnol Lett 27:327–334.
   PubMed Web of Science ®Google Scholar
• Lehmann M, Lopez-Ulibarri R, Loch C, Viarouge C, Wyss M, van Loon APGM. 2000. Exchanging the active site between phytases for altering the functional properties of the enzyme. Prot Sci 9:1866–1872.
   PubMed Web of Science ®Google Scholar
• Lei XG, Stahl CH. 2001. Biotechnological development of effective phytases for mineral nutrition and environmental protection. Appl Microbiol Biotechnol 57:474–481.
   PubMed Web of Science ®Google Scholar
• Li J, Hegeman CE, Hanlon RW, Lacy GH, Denbow DM, Grabau EA. 1997a. Secretion of active recombinant phytase from soybean cell-suspension cultures. Plant Physiol 114:1103–1111.
   PubMed Web of Science ®Google Scholar
• Li M, Osaki M, Honma M, Tadano T. 1997b. Purification and characterization of phytase induced in tomato roots under phosphorus-deficient conditions. Soil Sci Plant Nutr 43:179–190.
   Web of Science ®Google Scholar
• Li M, Osaki M, Rao IM, Tadano T. 1997c. Secretion of phytase from the roots of several plant species under phosphorus-deficient conditions. Plant Soil 195:161–169.
   Web of Science ®Google Scholar
• Lim D, Golovan S, Forsberg CW, Jia Z. 2000. Crystal structures of Escherichia coli phytase and its complex with phytate. Nat Struct Biol 7:108–113.
   PubMedGoogle Scholar
• Lonnerdal B, Bell JG, Hendrickx AG, Burns RA, Keen CL. 1988. Effect of phytate removal on zinc absorption from soy formula. Am J Clin Nutr 48:1301–1306.
   PubMed Web of Science ®Google Scholar
• Lucca P, Hurrell R, Potrykus I. 2001. Genetic engineering approaches to improve the bioavailability and the level of iron in rice grains. Theor Appl Genet 102:392–397.
   Web of Science ®Google Scholar
• Lung SC, Lim BL. 2006. Assimilation of phytate-phosphorus by the extracellular phytase activity of tobacco (Nicotiana tabacum) is affected by the availability of soluble phytate. Plant Soil 279: 187–199.
   Web of Science ®Google Scholar
• Maffucci T, Piccolo E, Cumashi A, Iezzi M, Riley AM, Siardi A, Godage HY, Rossi C, Broggini M, Iacobelli S, Potter BVL, Innocenti P, Falasca M. 2005. Inhibition of the phosphatidylinositol-3-kinase/Akt pathway by inositol pentakisphosphate results in antiangiogenic and antitumor effects. Cancer Res 65:8339–8349.
   PubMed Web of Science ®Google Scholar
• Marounek M, Duskova D, Skrivanova V. 2003. Hydrolysis of phytic acid and its availability in rabbits. Br J Nutr 89:287–294.
   PubMed Web of Science ®Google Scholar
• Maugenest S, Martinez I, Godin B, Perez P, Lescure AM. 1999. Structure of two maize phytase genes and their spatio-temporal expression during seedling development. Plant Mol Biol 39:503–514.
   PubMed Web of Science ®Google Scholar
• McCance RA, Widdowson EM. 1935. Phytin in human nutrition. Biochem J 29:2694–2699.
   PubMedGoogle Scholar
• McClung JP, Stahl CH, Marchitelli LJ, Morales-Martinez N, Mackin KM, Young AJ, Scrimgeour AG. 2006. Effects of dietary phytase on body weight gain, body composition and bone strength in growing rats fed a low-zinc diet. J Nutr Biochem 17:190–196.
   PubMed Web of Science ®Google Scholar
• McCollum EV, Hart EB. 1908. On the occurrence of a phytin-splitting enzyme in animal tissues. J Biol Chem 4:497–500.
   Google Scholar
• Meis SJ, Fehr WR, Schnebly SR. 2003. Seed source effect on field emergence of soybean lines with reduced phytate and raffinose saccharides. Crop Sci 43:1336–1339.
   Web of Science ®Google Scholar
• Mohanna C, Nys Y. 1999. Changes in zinc and manganese availability in broiler chicks induced by vegetal and microbial phytases. Anim Feed Sci Technol 77:241–253.
   Web of Science ®Google Scholar
• Mullaney EJ, Ullah AHJ. 1998. Identification of a histidine acid phosphatase (phyA)-like gene in Arabidopsis thaliana. Biochem Biophys Res Commun 251:252–255.
   PubMed Web of Science ®Google Scholar
• Mullaney EJ, Daly CB, Sethumadhavan K, Rodriguez E, Lei XG, Ullah AHJ. 2000. Phytase activity in Aspergillus fumigatus isolates. Biochem Biophys Res Commun 275:759–763.
   PubMed Web of Science ®Google Scholar
• Nwanna LC, Schwarz FJ. 2007. Effect of supplemental phytase on growth, phosphorus digestibility and bone mineralization of common carp (Cyprinus carpio L). Aquacult Res 38:1037–1044.
   Web of Science ®Google Scholar
• Oh BC, Choi WC, Park S, Kim YO, Oh TK. 2004. Biochemical properties and substrate specificities of alkaline and histidine acid phytases. Appl Microbiol Biotechnol 63:362–372.
   PubMed Web of Science ®Google Scholar
• Olukosi OA, Sands JS, Adeola O. 2007. Supplementation of carbohydrases or phytase individually or in combination to diets for weanling and growing-finishing pigs. J Anim Sci 85:1702–1711.
   PubMed Web of Science ®Google Scholar
• Onyango EM, Bedford MR, Adeola O. 2005. Efficacy of an evolved Escherichia coli phytase in diets of broiler chicks. Poult Sci 84:248–255.
   PubMed Web of Science ®Google Scholar
• Ostanin K, Van Etten RL. 1993. Asp304 of Escherichia coli acid phosphates is involved in leaving group protonation. J Biol Chem 268:20778–20784.
   PubMed Web of Science ®Google Scholar
• Palacios MC, Haros M, Rosell CM, Sanz Y. 2005. Characterization of an acid phosphatase from Lactobacillus pentosus: regulation and biochemical properties. J Appl Microbiol 98:229–237.
   PubMed Web of Science ®Google Scholar
• Palacios MC, Sanz Y, Haros M, Rosell CM. 2006. Application of Bifidobacterium strains to the breadmaking process. Process Biochem 41:2434–2440.
   Web of Science ®Google Scholar
• Palacios MC, Haros M, Sanz Y, Rosell CM. 2008a. Selection of lactic acid bacteria with high phytate degrading activity for application in whole wheat breadmaking. J Food Sci Technol 41:82–92.
   Google Scholar
• Palacios MC, Haros M, Sanz Y, Rosell CM. 2008b. Phytate degradation by Bifidobacterium on whole wheat fermentation. Food Microbiol 25:169–176.
   PubMed Web of Science ®Google Scholar
• Pasamontes L, Haiker M, Wyss M, Tessier M, van Loon APGM. 1997. Gene cloning, purification, and characterization of a heat-stable phytase from the fungus Aspergillus fumigatus. Appl Environ Microbiol 63:1696–1700.
   PubMed Web of Science ®Google Scholar
• Payne RL, Lavergne TK, Southern LL. 2005. A comparison of two sources of phytase in liquid and dry forms in broilers. Poult Sci 84:265–272.
   PubMed Web of Science ®Google Scholar
• Pen J, Verwoerd TC, van Paridon PA, Beudeker RF, van den Elzen PJM, Geerse K, van der Klis JD, Versteegh HAJ, van Ooyen AJJ, Hoekema A. 1993. Phytase-containing transgenic seeds as a novel feed additive for improved phosphorus utilization. Bio/Technology 11:811–814.
   Web of Science ®Google Scholar
• Peng RH, Yao QH, Xiong AS, Cheng ZM, Li Y. 2006. Codon-modifications and an endoplasmic reticulum-targeting sequence additively enhance expression of an Aspergillus phytase gene in transgenic canola. Plant Cell Rep 25:124–132.
   PubMed Web of Science ®Google Scholar
• Perić L, Milošević N, đukić-Stojčić M, Bjedov S, Rodić V. 2008. Effect of enzymes on performances of broiler chickens. Biotechnol Anim Husband 24:45–51.
   Google Scholar
• Pfeffer E. 1872. The inositol phosphates. Chemical synthesis and biological significance. Jahrb Wiss Bot 8:429.
   Google Scholar
• Phillippy BQ. 1998. Purification and catalytic properties of a phytase from scallion (Allium fistulosum L.) leaves. J Agric Food Chem 46:3491–3496.
   Web of Science ®Google Scholar
• Phillippy BQ. 1999. Susceptibility of wheat and Aspergillus niger phytases to inactivation by gastrointestinal enzymes. J Agric Food Chem 47:1385–1388.
   PubMed Web of Science ®Google Scholar
• Phillippy BQ, Mullaney EJ. 1997. Expression of an Aspergillus niger phytase (phy A) in Escherichia coli. J Agric Food Chem 45:3337–3342.
   Web of Science ®Google Scholar
• Pintar J, Bujan M, Homen B, Gazic K, Sikiric M, Cerny T. 2005. Effects of supplemental phytase on the mineral content in tibia of broilers fed different cereal based diets. Czech J Anim Sci 50:68–73.
   Web of Science ®Google Scholar
• Pirgozliev V, Oduguwa O, Acamovic T, Bedford MR. 2008. Effects of dietary phytase on performance and nutrient metabolism in chickens. Br Poult Sci 49:144–154.
   PubMed Web of Science ®Google Scholar
• Plimmer RHA. 1913. The metabolism of organic phosphorus compounds. Their hydrolysis by the action of enzymes. Biochem J 7:43–71.
   PubMedGoogle Scholar
• Ponstein AS, Bade JB, Verwoerd TC, Molendijk L, Storms J, Beudeker RF, Pen J. 2002. Stable expression of phytase (phyA) in canola (Brassica napus) seeds: towards a commercial product. Mol Breed 10:31–44.
   Web of Science ®Google Scholar
• Powar VK, Jagannathan V. 1982. Purification and properties of phytate-specific phosphatase from Bacillus subtilis. J Bacteriol 151:1102–1108.
   PubMed Web of Science ®Google Scholar
• Quan C, Zhang L, Wang Y, Ohta Y. 2001. Production of phytase in a low phosphate medium by a novel yeast Candida krusei. J Biosci Bioeng 92:154–160.
   PubMed Web of Science ®Google Scholar
• Quan CS, Fan SD, Zhang LH, Wang YJ, Ohta Y. 2002. Purification and properties of a phytase from Candida krusei WZ-001. J Biosci Bioeng 94:419–425.
   PubMed Web of Science ®Google Scholar
• Quan CS, Tian WJ, Fan SD, Kikuchi JI. 2004. Purification and properties of a low-molecular-weight phytase from Cladosporium sp. FP-1. J Biosci Bioeng 97:260–266.
   PubMed Web of Science ®Google Scholar
• Rao DECS. 2008. Cloning and expression of phytase gene from Bacillus species and evaluation of the enzyme as a feed additive. Ph.D. Thesis, Osmania University, Hyderabad, India.
   Google Scholar
• Rao DECS, Rao KV, Reddy VD. 2008. Cloning and expression of Bacillus phytase gene (phy) in Escherichia coli and recovery of active enzyme from the inclusion bodies. J Appl Microbiol 105:1128–1137.
   PubMed Web of Science ®Google Scholar
• Rasmus HN, Fuglsang CC, Arleth L, Westh P. 2006. Interrelationships of glycosylation and aggregation kinetics for Peniophora lycii phytase. Biochemistry 45:5057–5066.
   PubMed Web of Science ®Google Scholar
• Ravindran V, Bryden WL, Kornegay ET. 1995. Phytates: occurrence, bioavailability and implications in poultry nutrition. Poult Avian Biol Rev 6:125–143.
   Google Scholar
• Ravindran V, Cabahug S, Ravindran G, Bryden WL. 1999. Influence of microbial phytase on apparent ileal amino acid digestibility of feedstuffs for broilers. Poult Sci 78:699–706.
   PubMed Web of Science ®Google Scholar
• Reddy VA, Venu K, Rao DE, Rao KV, Reddy VD. 2009. Chimeric gene construct coding for bi-functional enzyme endowed with endoglucanase and phytase activities. Arch Microbiol 191:171–175.
   PubMed Web of Science ®Google Scholar
• Richardson NL, Higgs DA, Beames RM, McBride JR. 1985. Influence of dietary calcium, phosphorus, zinc and sodium phytate level on cataract incidence, growth and histopathology in juvenile Chinook salmon (Oncorhynchus tshawytscha). J Nutr 115:553–567.
   PubMed Web of Science ®Google Scholar
• Richardson AE, Hadobas PA, Hayes JE. 2000. Acid phosphomonoesterase and phytase activities of wheat (Triticum aestivum L.) roots and utilization of organic phosphorus substrates by seedlings grown in sterile culture. Plant Cell Environ 23:397–405.
   Web of Science ®Google Scholar
• Richardson AE, Hadobas PA, Hayes JE. 2001a. Extracellular secretion of Aspergillus phytase from Arabidopsis roots enables plants to obtain phosphorus from phytate. Plant J 25:641–649.
   PubMed Web of Science ®Google Scholar
• Richardson AE, Hadobas PA, Hayes JE, O’Hara CP, Simpson RJ. 2001b. Utilization of phosphorus by pasture plants supplied with myo-inositol hexaphosphate is enhanced by the presence of soil micro-organisms. Plant Soil 229:47–56.
   Web of Science ®Google Scholar
• Rodriguez E, Porres JM, Han Y, Lei XG. 1999. Different sensitivity of recombinant Aspergillus niger phytase (r-PhyA) and Escherichia coli pH 2.5 acid phosphatase (r-AppA) to trypsin and pepsin in vitro. Arch Biochem Biophys 365:262–267.
   PubMed Web of Science ®Google Scholar
• Rodriguez E, Mullaney EJ, Lei XG. 2000a. Expression of the Aspergillus fumigatus phytase gene in Pichia pastoris and characterization of the recombinant enzyme. Biochem Biophys Res Commun 268:373–378.
   PubMed Web of Science ®Google Scholar
• Rodriguez E, Wood ZA, Karplus PA, Lei XG. 2000b. Site-directed mutagenesis improves catalytic efficiency and thermostability of Escherichia coli pH 2.5 acid phosphatase/phytase expressed in Pichia pastoris. Arch Biochem Biophys 382:105–112.
   PubMed Web of Science ®Google Scholar
• Sajidan A, Farouk A, Greiner R, Jungblut P, Muller EC, Borris R. 2004. Molecular and physiological characterization of a 3-phytase from soil bacterium Klebsiella sp. ASR1. Appl Microbiol Biotechnol 65:110–118.
   PubMed Web of Science ®Google Scholar
• Sajjadi M, Carter CG. 2004. Effect of phytic acid and phytase on feed intake, growth, digestibility and trypsin activity in Atlantic salmon (Salmo salar, L). Aquacult Nutr 10:135–142.
   Web of Science ®Google Scholar
• Sandberg AS, Anderson H. 1988. Effect of dietary phytase on the digestion of phytate in the stomach and small intestine of humans. J Nutr 118:469–473.
   PubMed Web of Science ®Google Scholar
• Sandberg AS, Hulthen LR, Turk M. 1996. Dietary Aspergillus niger phytase increases iron absorption in humans. J Nutr 126:476–480.
   PubMed Web of Science ®Google Scholar
• Scott JJ. 1991. Alkaline phytase activity in nonionic detergent extracts of legume seeds. Plant Physiol 95:1298–1301.
   PubMed Web of Science ®Google Scholar
• Scott JJ, Loewus FA. 1986. A calcium-activated phytase from pollen of Lilium logiflorum. Plant Physiol 82:333–335.
   PubMed Web of Science ®Google Scholar
• Sebastian S, Touchburn SP, Chavez ER, Lague PC. 1997. Apparent digestibility of protein and amino acids in broiler chickens fed a corn-soybean diet supplemented with microbial phytase. Poult Sci 76:1760–1769.
   PubMed Web of Science ®Google Scholar
• Sebastian S, Touchburn SP, Chavez ER. 1998. Implications of phytic acid and supplemental microbial phytase in poultry nutrition: a review. World’s Poult Sci J 54:27–47.
   Web of Science ®Google Scholar
• Selle PH, Ravindran V, Caldwell RA, Bryden WL. 2000. Phytate and phytase: consequences for protein utilisation. Nutr Res Rev 13:255–278.
   PubMed Web of Science ®Google Scholar
• Shi J, Wang H, Schellin K, Li B, Faller M, Stoop JM, Meeley RB, Ertl DS, Ranch JP, Glassman K. 2007. Embryo-specific silencing of a transporter reduces phytic acid content of maize and soybean seeds. Nat Biotechnol 25:930–937.
   PubMed Web of Science ®Google Scholar
• Shimizu M. 1992. Purification and characterization of phytase and acid phosphatase produced by Aspergillus oryzae K1. Biosci Biotechnol Biochem 57:1364–1365.
   Web of Science ®Google Scholar
• Shin S, Ha NC, Oh BC, Oh TK, Oh BH. 2001. Enzyme mechanism and catalytic property of β propeller phytase. Structure 9:851–858.
   PubMed Web of Science ®Google Scholar
• Silva LG, Trugo LC. 1996. Characterization of phytase activity in Lupin seed. J Food Biochem 20:329–340.
   Web of Science ®Google Scholar
• Silversides FG, Scott TA, Bedford MR. 2004. The effect of phytase enzyme and level on nutrient extraction by broilers. Poult Sci 83:985–989.
   PubMed Web of Science ®Google Scholar
• Siren M. 1986a. Stabilized pharmaceutical and biological material composition. Patent SE 003165.
   Google Scholar
• Siren M. 1986b. New myo-inositol triphosphoric acid isomer. Patent SW 052950.
   Google Scholar
• Sutardi, Buckle KA. 1986. The characteristics of soybean phytase. J Food Biochem 10:197–216.
   Web of Science ®Google Scholar
• Suzuki U, Yoshimura K, Takaishi M. 1907. Ueber eon Enzym “Phytase” das “Anhydro-oxy-methylen diphosphorsaure.” Spaltet Tokyo Imper Univ Coll Agric Bull 7:503–512.
   Google Scholar
• Tomschy A, Tessier M, Wyss M, Brugger R, Broger C, Schnoebelen L, van Loon APGM, Pasamontes L. 2000. Optimization of the catalytic properties of Aspergillus fumigatus phytase based on the three-dimensional structure. Prot Sci 9:1304–1311.
   PubMed Web of Science ®Google Scholar
• Tseng YH, Fang TJ, Tseng SM. 2000. Isolation and characterization of a novel phytase from Penicillium simplicissimum. Folia Microbiol (Praha) 45:121–127.
   PubMed Web of Science ®Google Scholar
• Tye AJ, Siu FKY, Leung TYC, Lim BL. 2002. Molecular cloning and the biochemical characterization of two novel phytases from B. subtilis 168 and B. licheniformis. Appl Microbiol Biotechnol 59:190–197.
   PubMed Web of Science ®Google Scholar
• Uchida H, Arakida S, Sakamoto T, Kawasaki H. 2006. Expression of Aspergillus oryzae phytase gene in Aspergillus oryzae RIB40 niaD. J Biosci Bioeng 102:564–567.
   PubMed Web of Science ®Google Scholar
• Ullah AH, Dischinger HC Jr. 1993. Aspergillus ficuum phytase: complete primary structure elucidation by chemical sequencing. Biochem Biophys Res Commun 192:747–753.
   PubMed Web of Science ®Google Scholar
• Ullah AH, Sethumadhavan K. 1998. Differences in the active site environment of Aspergillus ficuum phytases. Biochem Biophys Res Commun 243:458–462.
   PubMed Web of Science ®Google Scholar
• Ullah AHJ, Sethumadhavan K, Mullaney EJ, Ziegelhoffer T, Austin-Phillips S. 2002. Cloned and expressed fungal phyA gene in alfalfa produces a stable phytase. Biochem Biophys Res Commun 290:1343–1348.
   PubMed Web of Science ®Google Scholar
• Ullah AHJ, Sethumadhavan K, Mullaney EJ, Ziegelhoffer T, Austin-Phillips S. 2003. Fungal phyA gene expressed in potato leaves produces active and stable phytase. Biochem Biophys Res Commun 306:603–609.
   PubMed Web of Science ®Google Scholar
• Van der Kaay J, Van Haastert PJ. 1995. Stereo-specificity of inositol hexakisphosphate dephosphorylation by Paramecium phytase. Biochem J 312:907–910.
   PubMed Web of Science ®Google Scholar
• Van Etten RL, Davidson R, Stevis PE, MacArthur H, Moore DL. 1991. Covalent structure, disulfide bonding, and identification of reactive surface and active site residues of human prostatic phosphatase. J Biol Chem 266:2313–2319.
   PubMed Web of Science ®Google Scholar
• Van Weerd JH, Khalaf KHA, Aartsen FJ, Tussen PAT. 1999. Balance trials with African catfish Clarias gariepinus fed phytase-treated soybean meal-based diets. Aquacult Nutr 5:135–142.
   Web of Science ®Google Scholar
• Vats P, Banerjee UC. 2005. Biochemical characterization of extracellular phytase (myo-inositol hexakisphosphate phosphohydrolase) from a hyper-producing strain of Aspergillus niger van Teighem. J Ind Microbiol Biotechnol 32:141–147.
   PubMed Web of Science ®Google Scholar
• Vats P, Bhattacharya MS, Banerjee UC. 2005. Uses of phytases (myo-inositolhexakisphosphate phosphohydrolases) for combating environmental pollution: a biological approach. Crit Rev Environ Sci Technol 35:469–486.
   Web of Science ®Google Scholar
• Verwoerd TC, van Paridon PA, van Ooyen AJJ, van Lent JWM, Hoekema A, Pen J. 1995. Stable accumulation of Aspergillus niger phytase in transgenic tobacco leaves. Plant Physiol 109:1199–1205.
   PubMed Web of Science ®Google Scholar
• Vielma J, Ruohonen K, Gabaudan J, Vogel K. 2004. Top-spraying soybean meal-based diets with phytase improves protein and mineral digestibilities but not lysine utilization in rainbow trout, Oncorhynchus mykiss (Walbaum). Aquacult Res 35:955–964.
   Web of Science ®Google Scholar
• Viveros A, Brenes A, Arija I, Centeno C. 2002. Effects of microbial phytase supplementation on mineral utilization and serum enzyme activities in broiler chicks fed different levels of phosphorus. Poult Sci 81:1172–1183.
   PubMed Web of Science ®Google Scholar
• Vohra A, Satyanarayana T. 2002. Purification and characterization of a thermostable and acid-stable phytase from Pichia anomala. World J Microbiol Biotechnol 18:687–691.
   Web of Science ®Google Scholar
• Vohra A, Satyanarayana T. 2003. Phytases: microbial sources, production, purification, and potential biotechnological applications. Crit Rev Biotechnol 23:29–60.
   PubMed Web of Science ®Google Scholar
• Wang X, Upatham S, Panbangred W, Isarangkul D, Summpunn P, Wiyakrutta Meevootisom V. 2004. Purification, characterization, gene cloning and sequence analysis of a phytase from Klebsiella pneumoniae subsp. pneumoniae XY-5. Sci Asia 30:383–390.
   Google Scholar
• Wang Y, Gao X, Su Q, Wu W, An L. 2007. Expression of a heat stable phytase from Aspergillus fumigatus in tobacco (Nicotiana tabacum L. cv. NC89). Ind J Biochem Biophys 44:26–30.
   PubMed Web of Science ®Google Scholar
• Woodzinski RJ, Ullah AHJ. 1996. Phytase. Adv Appl Microbiol 42: 263–303.
   PubMed Web of Science ®Google Scholar
• Wu G, Liu Z, Bryant MM, Roland DA Sr. 2006. Comparison of natuphos and phyzyme as phytase sources for commercial layers fed corn-soy diet. Poult Sci 85:64–69.
   PubMed Web of Science ®Google Scholar
• Wu YB, Ravindran V, Thomas DT, Camden BJ, Morel PCH, Hendriks WH, Pierce J. 2001. Efficacy of allzyme phytase produced by solid-state fermentation in improving the phosphorus availability of wheat-soybean meal diets for broilers. J Anim Sci 79(Suppl. 1/J).
   Google Scholar
• Wyss M, Pasamontes L, Remy R, Kohler J, Kusznir E, Gadient M, Muller F, van Loon APGM. 1998. Comparison of the thermostability properties of three acid phosphatases from molds: Aspergillus fumigatus phytase, A. niger phytase, and A. niger pH 2.5 acid phosphatase. Appl Environ Microbiol 64:4446–4451.
   PubMed Web of Science ®Google Scholar
• Wyss M, Brugger R, Kronenberger A, Remy R, Fimbel R, Oesterhelt G, Lehmann M, van Loon APGM. 1999a. Biochemical characterization of fungal phytases (myo-inositol hexakisphosphate phosphohydrolases): catalytic properties. Appl Environ Microbiol 65:367–373.
   PubMed Web of Science ®Google Scholar
• Wyss M, Pasamontes L, Friedlein A, Remy R, Tessier M, Kronenberger A, Middendorf A, Lehmann M, Schnoelbelen L, Rothlisberger U, Kusznir E, Wahl G, Muller F, Lahm HW, Vogel K, van Loon AP. 1999b. Biophysical characterization of fungal phytases (myo-inositol hexakisphosphate phosphohydrolases), molecular size, glycosylation pattern, and engineering of proteolytic resistance. Appl Environ Microbiol 65:359–366.
   PubMed Web of Science ®Google Scholar
• Xiao K, Harrison MJ, Wang ZY. 2005. Transgenic expression of a novel M. truncatula phytase gene results in improved acquisition of organic phosphorus by Arabidopsis. Planta 222:27–36.
   PubMed Web of Science ®Google Scholar
• Xiong AS, Yao QH, Peng RH, Zhnag Z, Xu F, Liu JG, Han PL, Chen JM. 2006. High level expression of a synthetic gene encoding Peniophora lycii phytase in methylotropic yeast Pichia pastoris. Appl Microbiol Biotechnol 72:1039–1047.
   PubMed Web of Science ®Google Scholar
• Yang WJ, Matsuda Y, Sano S, Masutami H, Nakagawa H. 1991. Purification and characterization of phytase from rat intestinal mucosa. Biochim Biophys Acta 1075:75–82.
   PubMed Web of Science ®Google Scholar
• Yanke LJ, Selinger LB, Cheng KJ. 1999. Phytase activity of Selenomonas ruminantium: a preliminary characterization. Lett Appl Microbiol 29:20–25.
   Web of Science ®Google Scholar
• Yin HF, Fan BL, Yang B, Liu YF, Luo J, Tian XH, Li N. 2006. Cloning of pig parotid secretory protein gene upstream promoter and the establishment of a transgenic mouse model expressing bacterial phytase for agricultural phosphorus pollution control. J Anim Sci 84:513–519.
   PubMed Web of Science ®Google Scholar
• Yip W, Wang L, Cheng C, Wu W, Lung S, Lim BL. 2003. The introduction of a phytase gene from Bacillus subtilis improved the growth performance of transgenic tobacco. Biochem Biophys Res Commun 310:1148–1154.
   PubMed Web of Science ®Google Scholar
• Yoon SJ, Choi YJ, Min HK, Cho KK, Kim JW, Lee SC, Jung YH. 1996. Isolation and identification of phytase-producing bacterium, Enterobacter sp. 4, and enzymatic properties of phytase enzyme. Enz Microbial Technol 18:449–454.
   Web of Science ®Google Scholar
• Zamudio M, Gonzalez A, Medina JA. 2001. Lactobacillus plantarum phytase activity is due to non-specific acid phosphatase. Lett Appl Microbiol 32:181–184.
   PubMed Web of Science ®Google Scholar
• Zhang L, An L, Gao X, Wang Y. 2004. Properties of A. ficuum AS3.324 phytase expressed in tobacco. Process Biochem 40:213–216.
   Web of Science ®Google Scholar
• Zimmermann P, Zardi G, Lehmann M, Zeder C, Amrhein N, Frossard E, Bucher M. 2003. Engineering the root-soil interface via targeted expression of a synthetic phytase gene in trichoblasts. Plant Biotechnol J 1:353–360.
   PubMed Web of Science ®Google Scholar
• Zinin NV, Serkina AV, Gelfand MS, Shevelev AB, Sineoky SP. 2004. Gene cloning, expression and characterization of novel phytase from Obesumbacterium proteus. FEMS Microbiol Lett 236:283–290.
   PubMed Web of Science ®Google Scholar
• Zyla K, Mika M, Stodolak B, Wikiera A, Koreleski J, Swiatkiewicz S. 2004. Towards complete dephosphorylation and total conversion of phytates in poultry feeds. Poult Sci 83:1175–1186.
   PubMed Web of Science ®Google Scholar