Relationships between endogenous circadian period, physiological and cognitive parameters and sex in aged gray mouse lemurs (Microcebus murinus)

References

• Albrecht U. 2017. Molecular mechanisms in mood regulation involving the circadian clock. Front Neurol. 8(FEB):1–6. doi:https://doi.org/10.3389/fneur.2017.00030
   PubMedGoogle Scholar
• Ashpole NM, Logan S, Yabluchanskiy A, Mitschelen MC, Yan H, Farley JA, Hodges EL, Ungvari Z, Csiszar A, Chen S, et al. 2017. IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan. GeroScience. 39(2):129–145. doi:https://doi.org/10.1007/s11357-017-9971-0
   PubMedGoogle Scholar
• Aujard F, Bluet-Pajot MT, Zizzari P, Perret M, Epelbaum J. 2010. IGF-1: A marker of individual life-span in a primate. Ageing Res. 1(1):2. doi:https://doi.org/10.4081/ar.2010.e2
   Google Scholar
• Aujard F, Cayetanot F, Bentivoglio M, Perret M. 2006. Age-related effects on the biological clock and its behavioral output in a primate. Chronobiol Int. 23(1–2):451–460. doi:https://doi.org/10.1080/07420520500482090
   PubMed Web of Science ®Google Scholar
• Aujard F, Cayetanot F, Terrien J, Van Someren EJW. 2007. Attenuated effect of increased daylength on activity rhythm in the old mouse lemur, a non-human primate. Exp Gerontol. 42(11):1079–1087. doi:https://doi.org/10.1016/j.molmet.2014.03.002
   PubMedGoogle Scholar
• Barclay JL, Tsang AH, and Oster H. 2012. Interaction of central and peripheral clocks in physiological regulation. In Progress in Brain Research, Vol. 199. . Elsevier B.V, pp. 163–181. doi:https://doi.org/10.1016/B978-0-444-59427-3.00030-7.
   Google Scholar
• Bennett S, and Ingram R. 2000. The effects of growth hormone and IGF-1 deficiency on cerebrovascular and brain ageing. J Anat. 1:575–585. doi:https://doi.org/10.1046/j.1469-7580.2000.19740575.x.
   Google Scholar
• Cai A, Scarbrough K, Hinkle DA, and Wise PM. 1997. Fetal grafts containing suprachiasmatic nuclei restore the diurnal rhythm of CRH and POMC mRNA in aging rats. Am J Physiol. 273(5 Pt 2):R1764–70. doi:https://doi.org/10.1152/ajpregu.1997.273.5.R1764.
   PubMedGoogle Scholar
• Carrier J, Paquet J, Morettini J, Touchette É. 2002. Phase advance of sleep and temperature circadian rhythms in the middle years of life in humans. Neurosci Lett. 320(1–2):1–4. doi:https://doi.org/10.1016/S0304-3940(02)00038-1
   PubMed Web of Science ®Google Scholar
• Carter CS, Ramsey MM, Sonntag WE, Carter CS, Ramsey MM, Sonntag WE. 2002. A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan. Trends Genet. 18(6):295–301. doi:https://doi.org/10.1016/S0168-9525(02)02696-3
   PubMedGoogle Scholar
• Cayetanot F, Nygård M, Perret M, Kristensson K, Aujard F. 2009. Plasma levels of interferon-γ correlate with age-related disturbances of circadian rhythms and survival in a non-human primate. Chronobiol Int. 26(8):1587–1601. doi:https://doi.org/10.3109/07420520903398518
   PubMed Web of Science ®Google Scholar
• Cayetanot F, Van Someren E, Perret M, Aujard F. 2005. Shortened seasonal photoperiodic cycles accelerate aging of the diurnal and circadian locomotor activity rhythms in a primate. J Biol Rhythms. 20(5):461–469. doi:https://doi.org/10.1177/0748730405279174
   PubMedGoogle Scholar
• Chellappa SL , Morris, CJ, and Scheer, FA. 2018. Circadian misalignment impacts on human cognitive performance. Sleep. 40(June):A77. doi:https://doi.org/10.1093/sleepj/zsx050.207.
   Google Scholar
• Craig LA, McDonald RJ. 2008. Chronic disruption of circadian rhythms impairs hippocampal memory in the rat. Brain Res Bull. 76(1–2):141–151. doi:https://doi.org/10.1016/j.brainresbull.2008.02.013
   PubMedGoogle Scholar
• Dal-pan A, Terrien J, Pifferi F, Botalla R, Hardy I, Marchal J, Zahariev A, Chery I, Zizzari P, Perret M, et al. 2011. Caloric restriction or resveratrol supplementation and ageing in a non-human primate: First-year outcome of the RESTRIKAL study in Microcebus murinus. Age (Omaha). 33(1):15–31. doi:https://doi.org/10.1007/s11357-010-9156-6
   Google Scholar
• Devan BD, Goad EH, Petri HL, Antoniadis EA, Hong NS, Ko CH, Leblanc L, Lebovic SS, Lo Q, Ralph MR, et al. 2001. Circadian phase-shifted rats show normal acquisition but impaired long-term retention of place information in the water task. Neurobiol Learn Mem. 75(1):51–62. doi:https://doi.org/10.1006/nlme.1999.3957
   PubMedGoogle Scholar
• Dubrovsky YV, Samsa WE, Kondratov RV. 2010. Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice. Aging (Albany NY). 2(12):936–944. doi:https://doi.org/10.18632/aging.100241
   PubMedGoogle Scholar
• Duffy JF, Cain SW, Chang AM, Phillips AJK, Munch MY, Gronfier C, Wyatt JK, Dijk D-J, Wright KP, Czeisler CA, et al. 2011. Sex difference in the near-24-hour intrinsic period of the human circadian timing system. Proc Natl Acad Sci U S A. 108(SUPPL. 3):15602–15608. doi:https://doi.org/10.1073/pnas.1010666108
   PubMed Web of Science ®Google Scholar
• Duong HA, Robles MS, Knutti D, Weitz C. 2011. A molecular mechanism for circadian clock negative feedback. Science (80-). 332(June):1436–1439. doi:https://doi.org/10.1126/science.1196766
   PubMedGoogle Scholar
• Eastman CI, Tomaka VA, Crowley SJ. 2017. Sex and ancestry determine the free-running circadian period. J Sleep Res. 26(5):547–550. doi:https://doi.org/10.1111/jsr.12521
   PubMed Web of Science ®Google Scholar
• Engstrom BE, Burman P, Holdstock C, Ohrvall M, Sundbom M, and Karlsson FA. 2006. Effects ofgastric bypass on the GH/IGF-I axis in severe obesity—and a comparison with GH deficiency. Eur. J. Endocrinol. 154:53–59. doi:https://doi.org/10.1530/eje.1.02069.
   PubMed Web of Science ®Google Scholar
• Farajnia S, Michel S, Deboer T, vanderLeest HT, Houben T, Rohling JHT, Ramkisoensing A, Yasenkov R, Meijer JH. 2012. Evidence for neuronal desynchrony in the aged suprachiasmatic nucleus clock. J Neurosci. 32(17):5891–5899. doi:https://doi.org/10.1523/JNEUROSCI.0469-12.2012
   PubMedGoogle Scholar
• Frater J, Lie D, Bartlett P, John M. 2017. Insulin-like growth factor 1 (IGF-1) as a marker of cognitive decline in normal ageing: A review. Ageing Res Rev. 42:14–27. doi:https://doi.org/10.1016/j.arr.2017.12.002
   PubMedGoogle Scholar
• Gary C, Lam S, Hérard AS, Koch JE, Petit F, Gipchtein P, Sawiak SJ, Caillierez R, Eddarkaoui S, Colin M, et al. 2019. Encephalopathy induced by Alzheimer brain inoculation in a non-human primate. Acta Neuropathol Commun. 7(1):126. doi:https://doi.org/10.1186/s40478-019-0771-x
   PubMedGoogle Scholar
• Gekakis N, Staknis D, Nguyen HB, Davis FC, Lisa D, King DP, Takahashi JS, Weitz CJ. 1998. Role of the CLOCK protein in the mammalian circadian mechanism controls the periodicity and persistence of role of the CLOCK protein the mammalian circadian mechanism in. Science (80-). 280(5369):1564–1569. doi:https://doi.org/10.1126/science.280.5369.1564
   PubMed Web of Science ®Google Scholar
• Génin F, Perret M. 2003. Daily hypothermia in captive grey mouse lemurs (Microcebus murinus): effects of photoperiod and food restriction. Comp Biochem Physiol - B Biochem Mol Biol. 136(1):71–81. doi:https://doi.org/10.1016/S1096-4959(03)00172-6
   PubMed Web of Science ®Google Scholar
• Gibson EM, Wang C, Tjho S, Khattar N, and Kriegsfeld LJ. 2010. Experimental “jet lag” inhibits adult neurogenesis and produces long-term cognitive deficits in female hamsters. Plos One. 5(12):e15267. doi:https://doi.org/10.1371/journal.pone.0015267.
   Google Scholar
• Grosbellet E, Zahn S, Arrivé M, Dumont S, Gourmelen S, Pévet P, Challet E, Criscuolo F. 2015. Circadian desynchronization triggers premature cellular aging in a diurnal rodent. FASEB J. 29(12):4794–4803. doi:https://doi.org/10.1096/fj.14-266817
   PubMedGoogle Scholar
• Gutman R, Genzer Y, Chapnik N, Miskin R, Froy O. 2011. Long-lived mice exhibit 24h locomotor circadian rhythms at young and old age. Exp Gerontol. 46(7):606–609. doi:https://doi.org/10.1016/j.exger.2011.02.015
   PubMed Web of Science ®Google Scholar
• Hozer C, Perret M, Pavard S, Pifferi F. 2020. Survival is reduced when endogenous period deviates from 24 h in a non ‑ human primate, supporting the circadian resonance theory. Sci Rep. 10:18002. doi:https://doi.org/10.1038/s41598-020-75068-8
   PubMedGoogle Scholar
• Hozer C, Pifferi F. 2020. Physiological and cognitive consequences of a daily 26h photoperiod in a primate. Proc R Soc B. 287(1931):20201079. doi:https://doi.org/10.1098/rspb.2020.1079
   PubMedGoogle Scholar
• Hozer C, Pifferi F, Aujard F, and Perret M. 2019. The biological clock in gray mouse lemur: adaptive, evolutionary and aging considerations in an emerging non-human primate model. Front Physiol. 10(August):1–23. doi:https://doi.org/10.3389/fphys.2019.01033.
   PubMedGoogle Scholar
• Kalsbeek A, La Fleur S, and Fliers E. 2014. Circadian control of glucose metabolism. Mol Metab. 3(4):372–383. doi:https://doi.org/10.1016/j.molmet.2014.03.002.
   PubMed Web of Science ®Google Scholar
• Kappeler L, De Magalhaes Filho C, Dupont J, Leneuve P, Cervera P, Périn L, Loudes C, Blaise A, Klein R, Epelbaum J, et al. 2008. Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism. PLoS Biol. 6(10):e254. doi:https://doi.org/10.1371/journal.pbio.0060254
   PubMedGoogle Scholar
• Karatsoreos IN, Bhagat S, Bloss EB, Morrison JH, McEwen BS. 2011. Disruption of circadian clocks has ramifications for metabolism, brain, and behavior. Proc Natl Acad Sci U S A. 108(4):1657–1662. doi:https://doi.org/10.1073/pnas.1018375108
   PubMed Web of Science ®Google Scholar
• Kondratov RV, Kondratova AA, Gorbacheva VY, Vykhovanets OV, Antoch MP. 2006. Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadian clock. Genes Dev. 20(14):1868–1873. doi:https://doi.org/10.1101/gad.1432206
   PubMed Web of Science ®Google Scholar
• Krizo JA, Mintz EM. 2015. Sex differences in behavioral circadian rhythms in laboratory rodents. Front Endocrinol (Lausanne). 5(DEC):3–6. doi:https://doi.org/10.3389/fendo.2014.00234
   Google Scholar
• Kyriacou CP, and Hastings MH. 2010. Circadian clocks: Genes, sleep, and cognition. Trends Cogn Sci. 14(6):259–267. doi:https://doi.org/10.1016/j.tics.2010.03.007.
   PubMed Web of Science ®Google Scholar
• Lande-Diner L, Boyault C, Kim JY, Weitz CJ. 2013. A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery. Proc Natl Acad Sci. 110(40):16021–16026. doi:https://doi.org/10.1073/pnas.1305980110
   PubMedGoogle Scholar
• Languille S, Blanc S, Blin O, Canale CI, Dal-Pan A, Devau G, Dhenain M, Dorieux O, Epelbaum J, Gomez D, Hardy I. 2012. The grey mouse lemur: A non-human primate model for ageing studies. Ageing Res Rev. 11(1):150–162. doi:https://doi.org/10.1016/j.arr.2011.07.001
   PubMedGoogle Scholar
• Languille S, Liévin-bazin A, Picq J, Louis C, Dix S, De Barry J, Blin O, Richardson J, Bordet R, Schenker E, Djelti F. 2015. Deficits of psychomotor and mnesic functions across aging in mouse lemur primates. Front Behav Neurosci. 8(January):1–13. doi:https://doi.org/10.3389/fnbeh.2014.00446
   Google Scholar
• Lashley KS. 1930. The mechanism of vision: I. A method for rapid analysis of pattern-vision in the rat. Pedagog Semin J Genet Psychol. 37(4):453–460. doi:https://doi.org/10.1080/08856559.1930.9944155.
   Google Scholar
• Lee H, Lee E, Moon J, Kim Y, Lee H. 2019. Circadian disruption and increase of oxidative stress in male and female volunteers after bright light exposure before bed time. Mol Cell Toxicol. 15(2):221–229. doi:https://doi.org/10.1007/s13273-019-0025-9
   Google Scholar
• Legates TA, Altimus CM, Wang H, Lee HK, Yang S, Zhao H, Kirkwood A, Weber ET, Hattar S. 2012. Aberrant light directly impairs mood and learning through melanopsin-expressing neurons. Nature. 491(7425):594–598. doi:https://doi.org/10.1038/nature11673
   PubMed Web of Science ®Google Scholar
• Li H, Satinoff E. 1998. Fetal tissue containing the suprachiasmatic nucleus restores multiple circadian rhythms in old rats. Am J Physiol Integr Comp Physiol. 275(6):1735–1744. doi:https://doi.org/10.1152/ajpregu.1998.275.6.R1735
   Google Scholar
• Libert S, Bonkowski MS, Pointer K, Pletcher SD, Guarente L. 2012. Deviation of innate circadian period from 24h reduces longevity in mice. Aging Cell. 11(5):794–800. doi:https://doi.org/10.1111/j.1474-9726.2012.00846.x
   PubMed Web of Science ®Google Scholar
• Lind MI, Ravindran S, Sekajova Z, Carlsson H, Hinas A, Maklakov AA. 2019. Experimentally reduced insulin/IGF-1 signaling in adulthood extends lifespan of parents and improves Darwinian fitness of their offspring. Evol Lett. 3(2):207–216. doi:https://doi.org/10.1002/evl3.108
   PubMedGoogle Scholar
• Lusk G. 1924. Animal calorimetry. Analysis of the oxidation of mixtures of carbohydrate and fat. J Biol Chem. 59(1):41–43. doi:https://doi.org/10.1016/S0021-9258(18)85293-0
   Google Scholar
• Ma W, Cao J, Tian M, Cui M, Han H, Yang YX, Xu L. 2007. Exposure to chronic constant light impairs spatial memory and influences long-term depression in rats. Neurosci Res. 59:224–230. doi:https://doi.org/10.1016/j.neures.2007.06.1474
   PubMed Web of Science ®Google Scholar
• Mao K, Quipildor GF, Tabrizian T, Novaj A, Guan F, Walters RO, Delahaye F, Hubbard GB, Ikeno Y, Ejima K, et al. 2018. Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice. Nat Commun. 9(2394):1–12. doi:https://doi.org/10.1038/s41467-018-04805-5
   PubMedGoogle Scholar
• Marchal J, Dal-pan A, Epelbaum J, Blanc S, Mueller S, Wittig Kieffer M, Metzger F, Aujard F, RESTRIKAL Consortium. 2013. Calorie restriction and resveratrol supplementation prevent age-related DNA and RNA oxidative damage in a non-human primate. Exp Gerontol. 48(9):992–1000. doi:https://doi.org/10.1016/j.exger.2013.07.002
   PubMedGoogle Scholar
• Martino TA, Oudit GY, Herzenberg AM, Tata N, Koletar MM, Kabir GM, Belsham DD, Backx PH, Ralph MR, and Sole MJ. 2008. Circadian rhythm disorganization produces profound cardiovascular and renal disease in hamsters. Am J Physiol - Regul Integr Comp Physiol. 294(5):R1675–83. doi:https://doi.org/10.1152/ajpregu.00829.2007.
   PubMed Web of Science ®Google Scholar
• Matikainen-Ankney BA, Garmendia-Cedillos M, Ali M, Krynitsky J, Salem G, Miyazaki NL, Pohida T, Kravitz AV. 2019. Rodent activity detector (RAD), an open source device for measuring activity in rodent home cages. eNeuro. 6(4):1–9. doi:https://doi.org/10.1523/ENEURO.0160-19.2019
   Google Scholar
• Moore RY. 2013. The suprachiasmatic nucleus and the circadian timing system. Progress in Molecular Biology and Translational Science. Vol. 119. 1st ed. Elsevier Inc.
   Google Scholar
• Morin LP, Fitzgerald KM, Zucker I. 1977. Estradiol shortens the period of hamster circadian rhythms. Science (80-). 196(4287):305–307. doi:https://doi.org/10.1126/science.557840
   PubMedGoogle Scholar
• Nakamura TJ, Tokuda IT, Ishikawa T, Nakamura W, Kudo T, Colwell CS, Block GD. 2015. age-related changes in the circadian system unmasked by constant conditions. eNeuro. 2(4):1–10. doi:https://doi.org/10.1523/ENEURO.0064-15.2015
   Google Scholar
• Naylor E, Bergmann BM, Krauski K, Zee PC, Takahashi JS, Vitaterna MH, Turek FW, et al. 2000. The circadian clock mutation alters sleep homeostasis in the mouse. J Neurosci. 20(21):8138–8143. doi:https://doi.org/10.1523/JNEUROSCI.20-21-08138.2000
   PubMedGoogle Scholar
• Niitepõld K, and Hanski I. 2013. A long life in the fast lane: positive association between peak metabolic rate and lifespan in a butterfly. J Exp Biol. 216(8):1388–1397. doi:https://doi.org/10.1242/jeb.080739.
   PubMedGoogle Scholar
• Onder G, Liperoti R, Russo A, Soldato M, Capoluongo E, Volpato S, Cesari M, Ameglio F, Bernabei R, and Landi F. 2006. Body mass index, free insulin-like growth factor I, and physical function among older adults: Results from the ilSIRENTE study. Am. J. Physiol. Endocrinol. Metab. 291:E829–E834. doi:https://doi.org/10.1152/ajpendo.00138.2006.
   PubMed Web of Science ®Google Scholar
• Perez-Campo R, López-Torres M, Cadenas S, Rojas C, Barja G. 1998. The rate of free radical production as a determinant of the rate of aging: Evidence from the comparative approach. J Comp Physiol - B Biochem Syst Environ Physiol. 168(3):149–158. doi:https://doi.org/10.1007/s003600050131
   PubMed Web of Science ®Google Scholar
• Perret M, Aujard F. 2001. Regulation by photoperiod of seasonal changes in body mass and reproductive function in gray mouse lemurs M murinus. Int J Primatol. 22(1):5–24. doi:https://doi.org/10.1023/A:1026457813626
   Web of Science ®Google Scholar
• Perret M, Aujard F. 2006. Vieillissement et rythmes biologiques chez les primates. Medecine/Sciences. 22(3):279–283. doi:https://doi.org/10.1051/medsci/2006223279
   Google Scholar
• Picq J. 1993. Radial maze performance in young and aged grey mouse lemurs (Microcebus murinus). Primates. 34(April):223–226. doi:https://doi.org/10.1007/BF02381394
   Google Scholar
• Picq J. 2007. Aging affects executive functions and memory in mouse lemur primates. Exp Gerontol. 42:223–232. doi:https://doi.org/10.1016/j.exger.2006.09.013
   PubMed Web of Science ®Google Scholar
• Picq J, Aujard F, Volk A, and Dhenain M. 2012. Age-related cerebral atrophy in nonhuman primates predicts cognitive impairments. NBA. 33(6):1096–1109. doi:https://doi.org/10.1016/j.neurobiolaging.2010.09.009.
   Google Scholar
• Picq J, Villain N, Gary C, Pifferi F, Dhenain M, Taffe M. 2015. Jumping stand apparatus reveals rapidly specific age-related cognitive impairments in mouse lemur primates. PLoS One. 10(12):1–11. doi:https://doi.org/10.1371/journal.pone.0146238
   Google Scholar
• Pifferi F, Rahman A, Languille S, Schenker E, Blin O, Irving E, Babiloni C. 2011 Nov. Sleep changes during aging: electroencephalography (EEG) study in a non-human primate. Soc Neurosci Washingt D C. 12–15.
   Google Scholar
• Pittendrigh C, Minis DH. 1972. Circadian systems: Longevity as a function of circadian resonance in Drosophila melanogaster. Proc Natl Acad Sci U S A. 69(6):1537–1539. doi:https://doi.org/10.1073/pnas.69.6.1537
   PubMed Web of Science ®Google Scholar
• Preuss F, Tang Y, Laposky AD, Arble D, Keshavarzian A, Turek FW. 2008. Adverse effects of chronic circadian desynchronization in animals in a “challenging” environment. Am J Physiol Integr Comp Physiol. 295(6):2034–2040. doi:https://doi.org/10.1152/ajpregu.00118.2008
   PubMed Web of Science ®Google Scholar
• Reinke H, Asher G. 2016. Circadian clock control of liver metabolic functions. Gastroenterology. 150(3):574–580. doi:https://doi.org/10.1053/j.gastro.2015.11.043
   PubMed Web of Science ®Google Scholar
• Richards J, Gumz ML. 2013. Mechanism of the circadian clock in physiology. Am J Physiol - Regul Integr Comp Physiol. 304(12). doi:https://doi.org/10.1152/ajpregu.00066.2013
   Google Scholar
• Ruby NF, Fernandez F, Garrett A, Klima J, Zhang P, Sapolsky R, Heller HC. 2013. Spatial memory and long-term object recognition are impaired by circadian arrhythmia and restored by the GABA A antagonist pentylenetetrazole. Plos One. 8(8):e72433. doi:https://doi.org/10.1371/journal.pone.0072433
   PubMedGoogle Scholar
• Ruby NF, Hwang CE, Wessells C, Fernandez F, Zhang P, Sapolsky R, Heller HC, et al. 2008. Hippocampal-dependent learning requires a functional circadian system. Proc Natl Acad Sci U S A. 105(40):15593–15598. doi:https://doi.org/10.1073/pnas.0808259105
   PubMed Web of Science ®Google Scholar
• Russo G, Curcio F, Bulli G, Aran L, Della-morte D, Gargiulo G, Testa G, Cacciatore F, Bonaduce D, Abete P. 2018. Oxidative stress, aging, and diseases. Clin Interv Aging. 13:757–772. doi:https://doi.org/10.2147/CIA.S158513
   PubMed Web of Science ®Google Scholar
• Scheer FAJL, Morris CJ, Shea SA. 2013. The internal circadian clock increases hunger and appetite in the evening independent of food intake and other behaviors. Obesity. 21(3):421–423. doi:https://doi.org/10.1002/oby.20351
   PubMed Web of Science ®Google Scholar
• Schmid J, Speakman JR. 2000. Daily energy expenditure of the grey mouse lemur (Microcebus murinus): A small primate that uses torpor. J Comp Physiol - B Biochem Syst Environ Physiol. 170(8):633–641. doi:https://doi.org/10.1007/s003600000146
   PubMedGoogle Scholar
• Schull J, Walker J, Fitzgerald K, Hiilivirta L, Ruckdeschel J, Schumacher D, Stanger D, McEachron DL, et al. 1989. Effects of sex, thyro-parathyroidectomy, and light regime on levels and circadian rhythms of wheel-running in rats. Physiol Behav. 46(3):341–346. doi:https://doi.org/10.1016/0031-9384(89)90001-2
   PubMedGoogle Scholar
• Sharma VK. 2003. Adaptive significance of circadian clocks. Chronobiol Int J Biol Med Rhythm Res. 20(6):901–919. doi:https://doi.org/10.1081/CBI-120026099.
   Google Scholar
• Sheeba V, Sharma VK. 1999. Adaptive significance of circadian rhythms biological clocks and Darwinian fitness in cyanobacteria. Resonance. (January):73–75. doi:https://doi.org/10.1007/BF02837157
   Google Scholar
• Sonntag WE, Ramsey M, Carter CS. 2005. Growth hormone and insulin-like growth factor-1 (IGF-1) and their influence on cognitive aging. Ageing Res Rev. 4:195–212. doi:https://doi.org/10.1016/j.arr.2005.02.001
   PubMed Web of Science ®Google Scholar
• Sonntag W, Lynch CD, Cefalu W, Ingram R, Bennett S, Thornton PL, Khan AS. 1999. Pleiotropic effects of growth hormone and insulin-like growth factor (IGF) -l on biological aging : inferences from moderate caloric-restricted animals. J Gerontol. 54(12):521–538. doi:https://doi.org/10.1093/gerona/54.12.B521
   Google Scholar
• Turek FW, Joshu C, Kohsaka A, Lin E, Ivanova G, McDearmon E, Laposky A, Losee-Olson S, Easton A, Jensen DR, Eckel RH. 2005. Obesity and metabolic syndrome in circadian clock mutant mice. Science (80-). 308(5724):1043–1045. doi:https://doi.org/10.1126/science.1108750
   PubMed Web of Science ®Google Scholar
• Viswanathan N, Davis FC. 1995. Suprachiasmatic nucleus grafts restore circadian function in aged hamsters. Brain Res. 686(1):10–16. doi:https://doi.org/10.1016/0006-8993(95)00423-N
   PubMedGoogle Scholar
• Vuarin P, Henry PY, Guesnet P, Alessandri JM, Aujard F, Perret M, Pifferi F. 2014. Shallow hypothermia depends on the level of fatty acid unsaturation in adipose and liver tissues in a tropical heterothermic primate. J Therm Biol. 43(1):81–88. doi:https://doi.org/10.1016/j.jtherbio.2014.05.002
   PubMedGoogle Scholar
• Witting W, Kwa IH, Eikelenboom P, Mirmiran M, Swaab DF. 1990. Alterations in the circadian rest-activity rhythm in aging and Alzheimers disease. Biol Psychiatry. 27:563–572. doi:https://doi.org/10.1016/0006-3223(90)90523-5
   PubMed Web of Science ®Google Scholar
• Wright KP, Lowry CA, and leBourgeois MK. 2012. Circadian and wakefulness-sleep modulation of cognition in humans. Front Mol Neurosci. 5(APRIL):1–12. doi:https://doi.org/10.3389/fnmol.2012.00050.
   PubMedGoogle Scholar
• Wyse CA, Coogan AN, Selman C, Hazlerigg DG, Speakman JR. 2010. Association between mammalian lifespan and circadian free-running period: The circadian resonance hypothesis revisited. Biol Lett. 6(5):696–698. doi:https://doi.org/10.1098/rsbl.2010.0152
   PubMed Web of Science ®Google Scholar
• Yan L, Silver R. 2016. Neuroendocrine underpinnings of sex differences in circadian timing systems. J Steroid Biochem Mol Biol. 160:118–126. doi:https://doi.org/10.1016/j.jsbmb.2015.10.007
   PubMed Web of Science ®Google Scholar
• Yoon I, Kripke DF, Elliott JA, Youngstedt SD, Rex KM, Hauger RL. 2003. Age-related changes of circadian rhythms and sleep-wake cycles. J Am Geriatr Soc. 51:1085–1091. doi:https://doi.org/10.1046/j.1532-5415.2003.51356.x
   PubMed Web of Science ®Google Scholar
• Yu W, Nomura M, Ikeda M. 2002. Interactivating feedback loops within the mammalian clock: BMAL1 is negatively autoregulated and upregulated by CRY1, CRY2, and PER2. Biochem Biophys Res Commun. 290(3):933–941. doi:https://doi.org/10.1006/bbrc.2001.6300
   PubMed Web of Science ®Google Scholar
• Zhu Y, Stevens RG, Hoffman AE, FitzGerald LM, Kwon EM, Ostrander EA, Davis S, Zheng T, Stanford JL. 2009. Testing the circadian gene hypothesis in prostate cancer: a population-based case-control study. Cancer Res. 69(24):9315–9322. doi:https://doi.org/10.1158/0008-5472.CAN-09-0648
   PubMed Web of Science ®Google Scholar