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ORIGINAL ARTICLE

Bone mineral density, body height, and vitamin D receptor gene polymorphism in middle‐aged men

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Pages 383-392 | Received 04 Dec 2004, Accepted 07 Jul 2005, Published online: 08 Jul 2009

References

  • Diaz M. N., O'Neill T. W., Silman A. J. The influence of family history of hip fracture on the risk of vertebral deformity in men and women: the European Vertebral Osteoporosis Study. Bone 1997; 20: 145–9
  • Cohen‐Solal M. E., Baudoin C., Omouri M., Kuntz D., De Vernejoul M. C. Bone mass in middle‐aged osteoporotic men and their relatives: familial effect. J Bone Miner Res 1998; 13: 1909–14
  • Bischoff‐Ferrari H. A., Dietrich T., Orav E. J., Dawson‐Hughes B. Positive association between 25‐hydroxy vitamin D levels and bone mineral density: a population‐based study of younger and older adults. Amer J Med 2004; 116: 634–9
  • Meier C., Woitge H. W., Witte K., Lemmer B., Seibel M. J. Supplementation with oral vitamin D3 and calcium during winter prevents seasonal bone loss: a randomized controlled open‐label prospective trial. J Bone Miner Res 2004; 19: 1221–30
  • Morrison N. A., Qi J. C., Tokita A., Kelly P. J., Crofts L., Nguyen T. V., et al. Prediction of bone density from vitamin D receptor alleles. Nature 1994; 367: 284–7
  • Kröger H., Mahonen A., Ryhänen S., Turunen A. ‐. M., Alhava E., Mäenpää P. Vitamin D receptor genotypes and bone mineral density. Lancet 1995; 345: 1238
  • Houston L. A., Grant S. F. A., Reid D. M., Ralston S. H. Vitamin D receptor polymorphism, bone mineral density, and osteoporotic vertebral fracture: studies in a UK population. Bone 1996; 18: 249–52
  • Salamone L. M., Ferrell R., Black D. M., Palermo L., Epstein R. S., Petro N., et al. The association between vitamin D receptor gene polymorphisms and bone mineral density at the spine, hip and whole‐body in premenopausal women. Osteoporosis Int. 1996;6:63–8. Erratum in Osteoporosis Int 1996; 6: 187–8
  • Gross C., Eccleshall T. R., Malloy P. J., Villa M. L., Marcus R., Feldman D. The presence of a polymorphism at the translation initiation site of the vitamin D receptor gene is associated with low bone mineral density in postmenopausal Mexican‐American women. J Bone Miner Res 1996; 11: 1850–5
  • Eccleshall T. R., Garnero P., Gross C., Delmas P. D., Feldman D. Lack of correlation between start codon polymorphism of the vitamin D receptor gene and bone mineral density in premenopausal French women: the OFELY study. J Bone Miner Res 1998; 13: 31–5
  • Gennari L., Becherini L., Mansani R., Masi L., Falchetti A., Morelli A., et al. FokI polymorphism at translation initiation site of the vitamin D receptor gene predicts bone mineral density and vertebral fractures in postmenopausal Italian women. J Bone Miner Res 1999; 14: 1379–86
  • Kanan R. M., Varanasi S. S., Francis R. M., Parker L., Datta H. K. Vitamin D receptor gene start codon polymorphism (FokI) and bone mineral density in healthy male subjects. Clin Endocrinol 2000; 53: 93–8
  • Tajima O., Ashizawa N., Ishii T., Amagai H., Mashimo T., Liu L. J., et al. Interaction of the effects between vitamin D receptor polymorphism and exercise training on bone metabolism. J Appl Physiol 2000; 88: 1271–76
  • Bell N. H., Morrison N. A., Nguyen T. V., Eisman J., Hollis B. W. ApaI polymorphisms of the vitamin D receptor predict bone density of the lumbar spine and not racial difference in bone density in young men. J Lab Clin Med 2001; 137: 133–40
  • Braga V., Sangalli A., Malerba G., Mottes M., Mirandola S., Gatti D., et al. Relationship among VDR (BsmI and FokI), COLIA1, and CTR polymorphisms with bone mass, bone turnover markers, and sex hormones in men. Calcif Tissue Int 2002; 70: 457–62
  • Uitterlinden A. G., Pols H. A. P., Burger H., Huang Q., van Daele P. L. A., van Duijn C. M., et al. A large‐scale population‐based study of the association of vitamin D receptor gene polymorphisms with bone mineral density. J Bone Miner Res 1996; 11: 1241–8
  • Gómez C., Naves M. L., Barrios Y., Díaz J. B., Fernández J. L., Salido E., et al. Vitamin D receptor gene polymorphisms, bone mass, bone loss and prevalence of vertebral fracture: Differences in postmenopausal women and men. Osteoporosis Int 1999; 10: 175–82
  • Need A. G., Horowitz M., Stiliano A., Scopacasa F., Morris H. A., Chatterton B. E. Vitamin D receptor genotypes are related to bone size and bone density in men. Eur J Clin Invest 1996; 26: 793–6
  • Francis R. M., Harrington F., Turner E., Papiha S. S., Datta H. K. Vitamin D receptor gene polymorphism in men and its effect on bone density and calcium absorption. Clin Endocrinol 1997; 46: 83–6
  • Crofts L. A., Hancock M. S., Morrison N. A., Eisman J. A. Multiple promoters direct the tissue‐specific expression of novel N‐terminal variant human vitamin D receptor gene transcripts. Proc Natl Acad Sci U S A 1998; 95: 10529–34
  • Miyamoto K., Kesterson R. A., Yamamoto H., Taketani Y., Nishiwaki E., Tatsumi S., et al. Structural organization of the human vitamin D receptor chromosomal gene and its promoter. Mol Endocrinol 1997; 11: 1165–79
  • Kiel D. P., Myers R. H., Cupples L. A., Kong X. F., Zhu X. H., Ordovas J., et al. The BsmI vitamin D receptor restriction fragment length polymorphism (bb) influences the effect of calcium intake on bone mineral density. J Bone Miner Res 1997; 12: 1049–57
  • Kurabayashi T., Matsushita H., Kato N., Nagata H., Kikuchi M., Tomita M., et al. Effect of vitamin D receptor and estrogen receptor gene polymorphism on the relationship between dietary calcium and bone mineral density in Japanese women. J Bone Miner Metab 2004; 22: 139–47
  • Lorentzon M., Lorentzon R., Nordström P. Vitamin D receptor gene polymorphism is associated with birth height, growth to adolescence, and adult stature in healthy Caucasian men: A cross‐sectional and longitudinal study. J Clin Endocrinol Metab 2000; 85: 1666–70
  • Suarez F., Zeghoud F., Rossignol C., Walrant O., Garabédian M. Association between vitamin D receptor gene polymorphism and sex‐dependent growth during the first two years of life. J Clin Endocrinol Metab 1997; 82: 2966–70
  • Schwartz Z., Schlader D. L., Ramirez V., Kennedy M. B., Boyan B. D. Effects of vitamin D metabolites on collagen production and cell proliferation of growth zone and resting zone cartilage cells in vitro. J Bone Miner Res 1989; 4: 199–207
  • Van Pottelbergh I., Goemaere S., De Bacquer D., De Paepe A., Kaufman M. Vitamin D receptor gene allelic variants, bone density, and bone turnover in community‐dwelling men. Bone 2002; 31: 631–7
  • Halleen J. M., Alatalo S. L., Suominen H., Cheng S., Janckila A. J., Väänänen H. K. Tartrate‐resistant acid phosphatase 5b: A novel serum marker of bone resorption. J Bone Miner Res 2000; 15: 1337–45
  • Morrison N. A., Yeoman R., Kelly P. J., Eisman J. A. Contribution of trans‐acting factor alleles to normal physiological variability: Vitamin D receptor gene polymorphisms and circulating osteocalcin. Proc Natl Acad Sci U S A 1992; 89: 6665–9
  • Pocock N. A., Eisman J. A., Hopper J. L., Yeates M. G., Sambrook P. N., Eberl S. Genetic determinants of bone mass in adults: A twin study. J Clin Invest 1987; 80: 706–10
  • Guéguen R., Jouanny P., Guillemin F., Kuntz C., Pourel J., Siest G. Segregation analysis and variance components analysis of bone mineral density in healthy families. J Bone Miner Res 1995; 10: 2017–22
  • Eliakim A., Raisz L. G., Brasel J. A., Cooper D. M. Evidence for increased bone formation following a brief endurance‐type training intervention in adolescent males. J Bone Miner Res 1997; 12: 1708–13
  • Menkes A., Mazel S., Redmond R. A., Koffler K., Libanati C. R., Gundberg C. M., et al. Strength training increases regional bone mineral density and bone remodeling in middle‐aged and older men. J Appl Physiol 1993; 74: 2478–84
  • Grisso J. A., Kelsey J. L., O'Brien L. A., Miles C. G., Sidney S., Maislin G., et al. Risk factors for hip fracture in men. Hip Fracture Study Group. Am J Epidemiol 1997; 145: 786–93
  • Brahm H., Mallmin H., Michaelsson K., Strom H., Ljunghall S. Relationships between bone mass measurements and lifetime physical activity in a Swedish population. Calcif Tissue Int 1998; 62: 400–12
  • Greendale G. A., Barrett‐Connor E., Edelstein S., Ingles S., Haile R. Lifetime leisure exercise and osteoporosis. The Rancho Bernardo study. Am J Epidemiol 1995; 141: 951–9
  • Huuskonen J., Väisänen S. B., Kröger H., Jurvelin J., Alhava E., Rauramaa R. Regular physical exercise and bone mineral density: A four year controlled randomised trial in middle‐aged men. Osteoporosis Int 2001; 12: 349–55
  • Rauramaa R., Kuhanen R., Lakka T. A., Väisänen S. B., Halonen P., Alén M., et al. Physical exercise and blood pressure with reference to the angiotensinogen M235T polymorphism. Physiol Genomics 2002; 10: 71–7
  • Huuskonen J., Väisänen S. B., Kröger H., Jurvelin J., Bouchard C., Alhava E., et al. Determinants of bone mineral density in middle‐aged men ‐ A population‐based study. Osteoporosis Int 2000; 11: 702–8
  • Glüer C. C., Blake G., Lu Y., Blunt B. A., Jergas M., Genant H. K. Accurate assessment of precision errors: How to measure the reproducibility of bone densitometry techniques. Osteoporosis Int 1995; 5: 262–70
  • Kröger H. Measurement of bone mass and density in children. Paediatric osteology: new developments in diagnostics and therapy, E Schönau. Elsevier Science, Amsterdam 1996; 103–8
  • Halleen J. M., Hentunen T. A., Hellman J., Väänänen H. K. Human bone tartrate‐resistant acid phosphatase: purification and development of an immunoassay. J Bone Miner Res 1996; 11: 1444–52
  • Weir B. S. Genetic data analysis. Methods for discrete population genetic data. Sinauer Associates, Inc, Sunderland, Massachusetts 1990
  • Hustmyer F. G., Peacock M., Hui S., Johnston C. C., Christian J. Bone mineral density in relation to polymorphism at the vitamin D receptor gene locus. J Clin Invest 1994; 94: 2130–4
  • Bonjour J. P., Carrié A. L., Ferrari S., Clavien H., Slosman D., Theintz G., et al. Calcium enriched foods and bone mass growth in prepubertal girls: a randomized, double‐blind, placebo‐controlled trial. J Clin Invest 1997; 99: 1287–94
  • Arai H., Miyamoto K. ‐I., Taketani Y., Yamamoto H., Iemori Y., Morita K., et al. A vitamin D receptor gene polymorphism in the translation initiation codon: effect on protein activity and relation to bone mineral density in Japanese women. J Bone Miner Res 1997; 12: 915–21
  • Jurutka P. W., Remus L. S., Whitfield G. K., Thompson P. D., Hsieh J. ‐C., Zitzer H., et al. The polymorphic N terminus in human vitamin D receptor isoforms influences transcriptional activity by modulating interaction with transcription factor IIB. Mol Endocrinol 2000; 14: 401–20
  • Whitfield G. K., Remus L. S., Jurutka P. W., Zitzer H., Oza A. K., Dang H. T. L., et al. Functionally relevant polymorphisms in the human nuclear vitamin D receptor gene. Mol Cell Endocrinol 2001; 177: 145–59
  • Fassbender W. J., Goertz B., Weismuller K., Steinhauer B., Stracke H., Au D., et al. VDR gene polymorphisms are overrepresented in German patients with type 1 diabetes compared to healthy controls without effect on biochemical parameters of bone metabolism. Horm Metab Res 2002; 34: 330–7
  • Järvinen T. L. N., Järvinen T. A. H., Sievänen H., Heinonen A., Tanner M., Huang X. ‐. H., et al. Vitamin D receptor alleles and bone's response to physical activity. Calcif Tissue Int 1998; 62: 413–7
  • Tsuritani I., Brooke‐Wavell K. S., Mastana S. S., Jones P. R., Hardman A. E., Yamada Y. Does vitamin D receptor polymorphism influence the response of bone to brisk walking in postmenopausal women?. Horm Res 1998; 50: 315–9

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