956
Views
46
CrossRef citations to date
0
Altmetric
Original Article

Overexpression of visfatin/PBEF/Nampt alters whole-body insulin sensitivity and lipid profile in rats

, , , , , , , & show all
Pages 311-320 | Received 29 Jul 2008, Published online: 08 Jul 2009

References

  • Kahn CR. Insulin action, diabetogenes, and the cause of type II diabetes. Diabetes. 1994; 43: 1066–84
  • Polonsky KS, Sturis J, Bell GI. Non-insulin-dependent diabetes mellitus––a genetically programmed failure of the beta cell to compensate for insulin resistance. N Engl J Med. 1996; 334: 777–83
  • Taylor SI. Insulin resistance or insulin deficiency: which is the primary cause of NIDDM?. Diabetes. 1994; 43: 735–40
  • Staiger H, Haring HU. Adipocytokines: fat-derived humoral mediators of metabolic homeostasis. Exp Clin Endocrinol Diab. 2005; 113: 67–79
  • Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedmen JM. Positional cloning of the mouse obese gene and its human homologue. Nature. 1994; 372: 425–32
  • Steppen CM, Bailey ST, Bhat S, Brown EJ, Banerjee RR, Wright CM, et al. The hormone resistin links obesity to diabetes. Nature. 2001; 409: 307–12
  • Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nature Med. 2001; 7: 941–6
  • Hug C, Lodish HF. Visfatin: A new adipokine. Science. 2005; 307: 366–7
  • Boucher J, Masri B, Daviaud D, Gesta S, Guigne C, Mazzucotelli A, et al. Apelin, a newly identified adipokine up-regulated by insulin and obesity. Endocrinology. 2005; 146: 1764–71
  • Fukuhara A, Matsuda M, Nishizawa M, Segawa K, Tanaka M, Kishimoto K, et al. Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science. 2005; 307: 426–30
  • Samal B, Sun Y, Stearns G, Xie C, Suggs S, McNiece I. Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor. Mol Cell Biol. 1994; 14: 1431–7
  • Fukuhara, A, Matsuda, M, Nishizawa, M, Segawa, K, Tanaka, M, Kishimoto, K, , et al. Science. 2007;318:565. Retraction of: Fukuhara A, Matsuda M, Nishizawa M, Segawa K, Tanaka M, Kishimoto K, et al. Science. 2005;307:426–30.
  • Beltowski J. Apelin and visfatin: Unique ‘beneficial’ adipokines upregulated in obesity?. Med Sci Monit. 2006; 12: RA112–9
  • Berndt J, Kloting N, Kralisch S. Plasma visfatin concentrations and fat depot-specific mRNA expression in humans. Diabetes. 2005; 54: 2911–16
  • Hammarstedt A, Pihlajamaki J, Sopasakis VR, Gogg S, Jansson PA, Laakso M, et al. Visfatin is an adipokine but it is not regulated by thiazolidinediones. J Clin Endocrinol Metab. 2006; 91: 1181–4
  • Chen MP, Chung FM, Chang DM, Tsai JR, Huang HF, Shin SJ, et al. Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab. 2006; 91: 295–9
  • Pagano C, Pilon C, Olivieri M, Mason P, Fabris R, Serra R, et al. Reduced plasma visfatin/pre-B cell colony- enhancing factor in obesity is not related to insulin resistance in humans. J Clin Endocrinol Metab. 2006; 91: 3165–70
  • Oki K, Yamane K, Kamei N, Nojima H, Kohno N. Circulating visfatin level is correlated with inflammation, but not with insulin resistance. Clin Endocrinol (Oxf) 2007; 67: 796–800
  • Yang G, Li L, Tang Y, Boden G. Short-term pioglitazone treatment prevents free fatty acid-induced hepatic insulin resistance in normal rats: Possible role of the resistin and adiponectin. Biochem Biophys Res Commun. 2006; 339: 1190–6
  • Hua Z, Xi Y, Naili W, Yaou Z, Guoping C. Macrostemonoside A promotes visfatin expression in 3T3-L1 cells. Biol Pharm Bull. 2007; 30: 279–83
  • Scribner KB, McGrane MM. RNA Polymerase II association with the phosphoenolpyruvate carboxykinase (PEPCK) promoter is reduced in vitamin A-deficient mice. J Nutr. 2003; 33: 4112–7
  • Miyazaki M, Kim YC, Ntambi JM. A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis. J Lipid Res. 2001; 42: 1018–24
  • Schweiger M, Schreiber R, Haemmerle G, Lass A, Fledelius C, Jacobsen P, et al. Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism. J Bio Chem. 2006; 286: 40236–41
  • Shin DJ, Osborne TF. Thyroid hormone regulation and cholesterol metabolism are connected through sterol regulatory element-binding protein-2 (SREBP-2). J Bio Chem. 2003; 278: 34114–8
  • Zeng L, Liao H, Liu Y, Lee TS, Zhu M, Wang X, et al. Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells. J Bio Chem. 2004; 279: 48801–7
  • Wahli W, Braissant O, Desvergne B. Peroxisome proliferators activated receptors: transcriptional regulation of adipogenesis, lipid metabolism and more. Chem Biol. 1995; 2: 261–6
  • Schoonjans K, Peinado Onsurbe J, Lefebvre AM, Heyman RA, Briggs M, Deeb S, et al. PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J. 1996; 15: 5336–48
  • Yamauchi T, Kamon J, Waki H, Murakami K, Motojima K, Komeda K, et al. The mechanisms by which both heterozygous peroxisome proliferator-activated receptor γ (PPARγ) deficiency and PPARγ agonist improve insulin resistance. J Biol Chem. 2001; 276: 41245–54
  • Berthiaume M, Sell H, Lalonde J, Gelinas Y, Tchernof A, Richard D, et al. Actions of PPARγ agonism on adipose tissue remodeling, insulin sensitivity, and lipemia in absence of glucocorticoids. Am J Physiol Regul Integr Comp Physiol. 2004; 287: R1116–23
  • Kharitonenkov A, Shiyanova TL, Koester A, Ford AM, Micanovic R, Galbreath EJ, et al. FGF-21 as a novel metabolic regulator. J Clin Invest. 2005; 115: 1627–35
  • Wente W, Efanov AM, Brenner M, Kharitonenkov M, Köster A, Sandusky GE, et al. Fibroblast growth factor-21 improves pancreatic ß-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways. Diabetes. 2006; 55: 2470–8

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.