74
Views
29
CrossRef citations to date
0
Altmetric
Article

Central obesity and hypertensive renal disease: association between higher levels of BMI, circulating transforming growth factor Β1 and urinary albumin excretion

, , , , , , & show all
Pages 269-276 | Received 28 May 2003, Accepted 12 Aug 2003, Published online: 08 Jul 2009

References

  • Must A, Spadano J, Coakley EH, et al. The disease burden associated with overweight and obesity. JAMA 1999; 282: 1523–9.
  • Doll S, Paccaud F, Bovel P, et al. Body mass index, abdominal adiposity and blood pressure: consistency of their association across developing and developed countries. Int J Obes 2002; 26: 48–57.
  • National Institutes of Health: United States Renal Data System: 1994 Annual Report, Ann Arbor, Michigan: University of Michigan, 1995.
  • Henegar JR, Bigler SA, Henegar LK, Tyagi SC, Hall JE. Functional and structural changes in the kidney in the early stages of obesity. J Am Soc Nephrol 2001; 12: 1211–17.
  • Licata G, Volpe M, Scaglione R, et al. Salt regulating hormones in young obese subjects. Effect of saline load. Hypertension 1994; 23 Suppl 1: 20–4.
  • Scaglione R, Ganguzza A, Corrao S, et al. Central obesity and hypertension: pathophysiologic role of renal haemody-namics and function. Int J Obesity 1995; 19: 403–9.
  • Weinstock W, Keane WF. Proteinuria and cardiovascular disease. Am J Kidney Dis 2001; 38 Suppl 1: S8–13.
  • Roberts AM, Sporn MB. Transforming growth factor #. Adv Cancer Res 1988; 51: 107–45.
  • Roberts AB, Mc Cune BK, Sporn MB. TGF-#: regulation of extracellular matrix. Kidney Int 1992; 41: 557–9.
  • Border WA, Nobel NA. Transforming growth factor-fl in tissue fibrosis. N Engl J Med 1994; 331: 1286–92.
  • Bottinger EP, Letterio JJ, Roberts AB. Biology of TGF-# in knockout and transgenic mouse models. Kidney Int 1997; 51: 1255–360.
  • Tamaki K, Okuda S, Nakayama M, et al. Transforming growth factor-beta 1 in hypertensive renal injury in Dahl salt sensitive rats. J Am Soc Nephrol 1996; 7: 2578–89.
  • Villarreal FJ, Dillmann WH. Cardiac hypertrophy-induced changes in mRNA levels for TGFS, fibronectin, and collagen. Am J Physiol 1992; 262: H1861–6.
  • Gibbons GH, Dzau VJ. The emerging concept of vascular remodeling. N Engl J Med 1994; 330: 1431–8.
  • Laviades C, Varo N, Diez J. Transforming growth factor # in hypertensives with cardiorenal damage. Hypertension 2000; 36: 517–22.
  • Porreca E, Di Febbo C, Vitacolonna E, et al. Transforming growth factor-#1 levels in hypertensive patients: association with body mass index and leptin. Am J Hyper 2002; 15: 759–65.
  • Joint National Committee on Prevention, Detection, Evalu-ation, and Treatment of High Blood Pressure. The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Arch Intern Med 1997; 157: 2413–46.
  • Crepaldi G, Belfiore F, Bosello 0, et al. Special report: Italian Consensus Conference - Overweight, Obesity and Health. Int J Obesity 1991; 15: 781–90.
  • Khanna A, Li B, Stenzel KH, et al. Regulation of new DNA synthesis in mammalian cells by cyclosporine: demonstra-tion of a transforming growth # factor dependent mechanism of inhibition of cell growth. Transplantation 1994; 57: 577–82.
  • de Simone G, Devereux RB, Daniels SR, et al. Effect of growth on variability of left ventricular mass: assessment of allometric signals in adults and children and their capacity to predict cardiovascular risk. J Am Coll Cardiol 1995; 25: 1056–62.
  • de Simone G, Daniels SR, Devereux RB, et al. Left ventricular mass and body size in normotensive children and adults: assessment of allometric relations and impact of overweight. J Am Coll Cardiol 1992; 20: 1251–60.
  • de Simone G, Devereux RB, Roman MJ, et al. Relation of obesity and gender to left ventricular hypertrophy in normotensive and hypertensive adults. Hypertension 1994; 23: 600–6.
  • Urbina EM, Gidding SS, Bao W, et al. Effects of body size, ponderosity and blood pressure on left ventricular growth in children and young adults in the Bogalusa Heart Study. Circulation 1995; 25: 1056–62.
  • Wyatt HL, Meerbaum S, Heng MK, et al. Cross sectional echocardiography III. Analysis of mathematic models for quantifying volume of symmetric and asymmetric left ventricular. Am Heart J 1980; 100: 821–8.
  • Corrao S, Scaglione R, Arnone S, et al. Left ventricular diastolic filling alterations in subjects with mitral valve prolapse: a Doppler echocardiography study. Eur Heart J 1993; 14: 369–72.
  • Watchtell K, Bella JN, Lieb son PR, et al. Impact of different partition values on prevalences of left ventricular hyper-trophy and concentric geometry in a large hypertensive population: the LIFE study. Hypertension 2000; 35: 6–12.
  • Suthanthiran M, Li B, Song JO, et al. Transforming growth factor #1 hyperexpression in African-American hyperten-sives: a novel mediator of hypertension and/or target organ damage. Proc Natl Acad Sci USA 2000; 97: 3479–84.
  • Ketteler M, Noble NA, Border WA. Increased expression of transforming growth factor beta in renal disease. Curr Opin Nephrol Hypert 1994; 3: 446–52.
  • Grainger DJ, Heathcote K, Chiano M, et al. Genetic control of the circulating concentration of transforming growth factor type #1. Hum Mol Genet 1999; 8: 93–7.
  • Kim S, Ohta K, Hamaguchi A, et al. Angiotensin II type 1 receptor antagonist inhibits the gene expression of trans-forming growth factor-betal and extracellular matrix in cardiac and vascular tissues of hypertensive rats. J Pharmacol Exp Ther 1995; 273: 509–15.
  • Negishi M, Lu D, Zhang Y-Q, et al. Up-regulatory expression of furin and transforming growth factor # by fluid shear stress in vascular endothelial cells. Arterioscl Thromb Vase Biol 2001; 21: 785–90.
  • Samad F, Yamamoto K, Pandey M, et al. Elevated expression transforming growth factor type beta in adipose tissue from obese mice. Mol Med 1997; 3: 37–48.
  • Alessi MC, Bastelica D, Morange P, et al. Plasminogen activator inhibitor, transforming growth factor-fl, and BMI are closely associated in human adipose tissue during morbid obesity. Diabetes 2000; 49: 1374–1380.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.