Treatment of agitation in the acute psychiatric setting. An observational study of the effectiveness of intramuscular psychotropic medication

References

• Zeller S, Rhoades RW. Systematic reviews of assessment measures and pharmacologic treatments for agitation. Clin Ther 2010;32:403–25.
   PubMed Web of Science ®Google Scholar
• Zimbroff DL. Pharmacological control of acute agitation: focus on intramuscular preparations. CNS Drugs 2008;22:199–212.
   PubMed Web of Science ®Google Scholar
• Gates DM, Ross CS, McQueen L. Violence against emergency department workers. J Emerg Med 2006;31:331–7.
   PubMed Web of Science ®Google Scholar
• Duhart DT. Violence in the Workplace, 1993–99. Washington, DC: US Department of Justice Programs; 2001.
   Google Scholar
• Richmond JS, Berlin JS, Fishkind AB, Holloman GH, Jr., Zeller SL, Wilson MP, et al. Verbal de-escalation of the agitated patient: consensus statement of the American association for emergency psychiatry project BETA de-escalation workgroup. West J Emerg Med 2012;13:17–25.
   PubMedGoogle Scholar
• Stowell KR, Florence P, Harman HJ, Glick RL. Psychiatric evaluation of the agitated patient: consensus statement of the American association for emergency psychiatry project Beta psychiatric evaluation workgroup. West J Emerg Med 2012;13:11–6.
   PubMedGoogle Scholar
• Meehan K, Zhang F, David S, Tohen M, Janicak P, Small J, et al. A double-blind, randomized comparison of the efficacy and safety of intramuscular injections of olanzapine, lorazepam, or placebo in treating acutely agitated patients diagnosed with bipolar mania. J Clin Psychopharmacol 2001;21:389–97.
   PubMed Web of Science ®Google Scholar
• Currier GW, Chou JC, Feifel D, Bossie CA, Turkoz I, Mahmoud RA, et al. Acute treatment of psychotic agitation: a randomized comparison of oral treatment with risperidone and lorazepam versus intramuscular treatment with haloperiodol and lorazepam. J Clin Psychiatry 2004;65:386–94.
   PubMed Web of Science ®Google Scholar
• Citrome L. Comparison of intramuscular ziprasidone, olanzapine or aripiprazole for agitation: A quantitative review of efficacy and safety. J Clin Psychiatry 2007;68:1876–85.
   PubMed Web of Science ®Google Scholar
• Breier A, Meehan K, Birkett M, David S, Ferchland I, Sutton V, et al. A double-blind, placebo-controlled dose-response comparison of intramuscular olanzapine and haloperidol in the treatment of acute agitation in schizophrenia. Arc Gen Psychiatry 2002;59:441–8.
   PubMed Web of Science ®Google Scholar
• Chaichan W. Evaluation of the use of the positive and negative syndrome scale-excited component as a criterion for administration of p.r.n. medication. J Psychiatr Pract 2008;14:105–13.
   PubMed Web of Science ®Google Scholar
• Damsa C, Ikelheimer D, Adam E, Maris S, Andreoli A, Lazignac C, et al. Heisenberg in the ER: Observation appears to reduce involuntary intramuscular injections in psychiatric emergency service. Gen Hosp Psychiatry 2006;28:431–3.
   PubMed Web of Science ®Google Scholar
• Almvik R, Woods P, Rasmussen K. The Broeset violence checklist. Sensitivity, specificity and interrater realibilify. J Interpers Violence 2000;15:1284–96.
   Web of Science ®Google Scholar
• Daniel DG, Potkin SG, Reeves KR, Swift RH, Harrigan EP. Intramuscular (IM) ziprasidone 20 mg is efective in reducing acute agitation associated with psychosis: A double-blind, randomized trial. Psychopharmacology 2001;155:128–34.
   PubMed Web of Science ®Google Scholar
• Tran-Johnson TK, Sack DA, Marcus RN, Auby P, McQuade R, Oren DA. Efficacy and safety of intramuscular aripiprazole in patients with acute agitation: A randomized, double-blind, placebo-controlled trial. J Clin Psychiatry 2007;68:111–9.
   PubMed Web of Science ®Google Scholar
• Wright P, Birkett M, David S, Meehan K, Ferchland I, Alaka KJ, et al. Double-blind, placebo-controlled comparison of intramuscular olanzapine and intramuscular haloperidol in the treatment of acute agitation in schizophrenia. Am J Psychiatry 2001;158:1149–51.
   PubMed Web of Science ®Google Scholar
• Chan HY, Ree SC, Su LW, Chen JJ, Chou SY, Chen CK, et al. A. double-blind randomized comparison study of efficacy and safety of intramuscular olanzapine and intramuscular haloperidol in patients with schizophrenia and acute agitated behavior. J Clin Psychopharmacol 2014;34:355–8.
   PubMed Web of Science ®Google Scholar
• Huang CL, Hwang TJ, Chen YH, Huang GH, Hsieh MH, Chen HH, et al. Intramuscular olanzapine versus intramuscular haloperidol plus lorazepam for the treatment of acute schizophrenia with agitation: An open-label, randomized controlled trial. J Formos Med Assoc 2015;114:438–45.
   PubMed Web of Science ®Google Scholar
• Psykiatriloven. LBK NR. 1729. Bekendtgørelse af lov om anvendelse af tvang i psykiatrien. 2001.
   Google Scholar
• Gardner DM, Murphy AL, ÓDonnel H, Centurrino F, Baldessarini RJ. International consensus study of antipsychotic dosing. Am J Psychiatry 2001;167:686–93.
   Google Scholar
• Ashton C. Benzo.org-uk. [Internet] Newcastle University. 2002. [Revised August 2002, cited June 2015]. Available from: http://www.benzo.org.uk/manual/bzcha01.htm#24
   Google Scholar
• Damsa C, Adam E, Lazignac C, Mihai A, DE Gregorio F, Lejeune J, et al. A naturalistic study of consecutive agitated emergency department patients treated with intramuscular olanzapine prior to consent. Am J Psychiatry 2008;165:535–6.
   PubMed Web of Science ®Google Scholar
• Centorrino F, Meyers AL, Ahl J, Cincotta SL, Zun L, Gulliver AH, et al. An observational study of the effectiveness and safety of intramuscular olanzapine in the treatment of acute agitation in patients with bipolar mania or schizophrenia/schizoaffective disorder. Hum Psychopharmacol 2007;22:455–62.
   PubMed Web of Science ®Google Scholar
• Perrin E, Anand E, Dyachkova Y, Wagner T, Frediani S, Ballerini A, OBS-IM investigators group. A prospective observational study of the safety and effectiveness of intramuscular psychotropic treatment in acutely agitated patients with schizphrenia and bipolar mania. Eur Psychiatry 2012;27:234–9.
   PubMed Web of Science ®Google Scholar
• Preval H, Klotz SG, Southard R, Francis A. Rapid-acting IM ziprasidone in a psychiatric emergency service: a naturalistic study. Gen Hosp Psychiatry 2005;27:140–4.
   PubMed Web of Science ®Google Scholar
• De Filippis S, Cuomo I, Lionetto L, Janiri D, Simmaco M, Caloro M, et al. Intramuscular aripiprazole in the acute management of psychomotor agitation. Pharmacotherapy 2013;33:603–14.
   PubMed Web of Science ®Google Scholar
• San L, Arranz B, Querejeta I, Barrio S, De la Gándara J, Pérez V. A naturalistic multicenter study of intramuscular olanzapine in the treatment of acutely agitated manic or schizophrenic patients. Eur Psychiatry 2006;21:539–43.
   PubMed Web of Science ®Google Scholar
• Suzuki H, Gen K, Takahashi Y. A naturalistic comparison study of the efficacy and safety of intramuscular olanzapine, intramuscular haloperidol, and intramuscular levomepromazine in acute agitated patients with schizophrenia. Hum Psychomarcol 2014;29:83–8.
   Web of Science ®Google Scholar
• Allen MH, Currier GW, Carpenter D, Ross RW, Docherty JP. Expert consensus panel for behavioral emergencies 2005. J Psychiatr Pract 2005;11:5–108.
   PubMedGoogle Scholar
• Battaglia J, Lindborg SR, Alaka K, Meehan K, Wright P. Calming versus sedative effects of intramuscular olanzapine in agitated patients. Am J Emerg Med 2003;21:192–8.
   PubMed Web of Science ®Google Scholar