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Articles

Serum nesfatin-1, ghrelin, and lipid levels in adolescents with first episode drug naïve unipolar depression

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Pages 613-619 | Received 02 Mar 2020, Accepted 18 May 2020, Published online: 04 Jun 2020

References

  • American Psychiatric Association. 2013. Diagnostic and statistical manual of mental disorders. (5th ed.). Arlington (VA): Author.
  • Brent DA. Depressive disorders. In: Martin A, Volkmar F, editors. Lewis’s child and adolescent psychiatry: a comprehensive textbook. 4th ed. Philadelphia (PA): Wolters Kluwers; 2007. p. 503–512.
  • Colich NL, Kircanski K, Foland-Ross LC, et al. HPA-axis reactivity interacts with stage of pubertal development to predict the onset of depression. Psychoneuroendocrinology 2015;55:94–101.
  • Hacimusalar Y, Eşel E. Suggested biomarkers for major depressive disorder. Noropsikiyatri Ars 2018;55(3):280-290.
  • Oh-I S, Shimizu H, Satoh T, et al. Identification of nesfatin-1 as a satiety molecule in the hypothalamus. Nature. 2006;443(7112):709–712.
  • Stengel A. Nesfatin-1 - more than a food intake regulatory peptide. Peptides. 2015;72:175–183.
  • Merali Z, Cayer C, Kent P, et al. Nesfatin-1 increases anxiety- and fear-related behaviors in the rat. Psychopharmacology (Berl). 2008;201(1):115–123.
  • Ge JF, Xu YY, Qin G, et al. Depression-like behavior induced by nesfatin-1 in rats: Involvement of increased immune activation and imbalance of synaptic vesicle proteins. Front Neurosci. 2015;9:429.
  • Dore R, Levata L, Lehnert H, et al. Nesfatin-1: functions and physiology of a novel regulatory peptide. J Endocrinol. 2017;232(1):45–65.
  • Kojima M, Hosoda H, Date Y, et al. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature. 1999;402(6762):656–660.
  • Kluge M, Schüssler P, Bleninger P, et al. Ghrelin alone or co-administered with GHRH or CRH increases non-REM sleep and decreases REM sleep in young males. Psychoneuroendocrinology. 2008;33(4):497–506.
  • Andrews ZB. The extra-hypothalamic actions of ghrelin on neuronal function. Trends Neurosci. 2011;34:31–40.
  • Chuang JC, Zigman JM. Ghrelin’s roles in stress, mood, and anxiety regulation. Int J Pept. 2010;2010:1–5.
  • Jerlhag E, Egecioglu E, Landgren S, et al. Requirement of central ghrelin signaling for alcohol reward. Proc Natl Acad Sci USA. 2009;106(27):11318–11323.
  • Ozsoy S, Besirli A, Abdulrezzak U, et al. Serum ghrelin and leptin levels in patients with depression and the effects of treatment. Psychiatry Investig. 2014;11(2):167–172.
  • Tunçel ÖK, Akbaş S, Bilgici B. Increased ghrelin levels and unchanged adipocytokine levels in major depressive disorder. J Child Adolesc Psychopharmacol. 2016;26(8):733–739.
  • Pae C-U. Comment on: the relationship between statins and depression: a review of the literature. Expert Opin Pharmacother. 2013;14(17):2449–2451.
  • Enko D, Brandmayr W, Halwachs-Baumann G, et al. Prospective plasma lipid profiling in individuals with and without depression. Lipids Health Dis. 2018;17(1):149.
  • Rao U. Biomarkers in pediatric depression. Depress Anxiety. 2013;30(9):787–791.
  • Kovacs M. The Children’s Depression, Inventory (CDI). Psychopharmacol Bull. 1985;21:995–998.
  • Oy B. Children’s Depression Inventory: validity and reliability study. Turk J Psychiatry. 1991;2:132–136.
  • Birmaher B, Khetarpal S, Brent D, et al. The Screen for Child Anxiety Related Emotional Disorders (SCARED): scale construction and psychometric characteristics. J Am Acad Child Adolesc Psychiatry. 1997;36:545–553.
  • Karaceylan F.[Reliability and validity of SCARED in Turkish children][PhD dissertation]. Kocaeli: Kocaeli University; 2005.
  • Cull JG, Gill WS. Suicide probability scale. West Psychol Serv. 1982.
  • Kaufman J, Birmaher B, Brent D, et al. Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): initial reliability and validity data. J Am Acad Child Adolesc Psychiatry. 1997;36(7):980–988.
  • Gokler B, Unal F, Pehlivanturk B, et al. Reliability and validity of schedule for affective disorders and schizophrenia for school age children-present and lifetime version-Turkish version (K-SADS-PL-T). Turk J Child Adolesc Ment Heal. 2004;11:109–116.
  • Gok YD, Minbay Z, Eyigor O. Besin Alımının Kontrolündeki Anoreksijenik Peptit: Nesfatin-1. Uludağ Üniversitesi Tıp Fakültesi Derg. 2018;44:135–142.
  • Ari M, Ozturk OH, Bez Y, et al. High plasma nesfatin-1 level in patients with major depressive disorder. Prog Neuro-Psychopharmacology Biol Psychiatry. 2011;35(2):497–500.
  • Gunay H, Tutuncu R, Aydin S, et al. Decreased plasma nesfatin-1 levels in patients with generalized anxiety disorder. Psychoneuroendocrinology. 2012;37(12):1949–1953.
  • Korucu CÇ, Atay İM, Zayıf SS, et al. May nesfatin-1 be a state marker in major depressive disorder with suicidal ideation? Psychiatry Res. 2018;267:272–276.
  • Wei Y, Li J, Wang H, et al. NUCB2/nesfatin-1: expression and functions in the regulation of emotion and stress. Prog Neuro-Psychopharmacol Biol Psychiatry. 2018;81:221–227.
  • Ishitobi Y, Kohno K, Kanehisa M, et al. Serum ghrelin levels and the effects of antidepressants in major depressive disorder and panic disorder. Neuropsychobiology. 2012;66(3):185–192.
  • Algul S, Ozcelik O. Evaluating the levels of nesfatin-1 and ghrelin hormones in patients with moderate and severe major depressive disorders. Psychiatry Investig. 2018;15(2):214–218.
  • Kristensson E, Sundqvist M, Håkanson R, et al. High gastrin cell activity and low ghrelin cell activity in high-anxiety Wistar Kyoto rats. J Endocrinol. 2007;193(2):245–250.
  • Kageyama H, Takenoya F, Shioda S. Morphological analysis of ghrelin neurons in the hypothalamus. Methods Enzymol. 2012;514:91–99.
  • Carlini VP, Gaydou RC, Schiöth HB, et al. Selective serotonin reuptake inhibitor (fluoxetine) decreases the effects of ghrelin on memory retention and food intake. Regul Pept. 2007;5;140(1-2):65–73.
  • Wittekind DA, Kluge M. Ghrelin in psychiatric disorders - A review. Psychoneuroendocrinology. 2015;52:176–194.
  • Pompili M, Longo L, Dominici G, et al. Polyunsaturated fatty acids and suicide risk in mood disorders: A systematic review. Prog Neuro-Psychopharmacol Biol Psychiatry. 2017;74:43–56.
  • Muldoon MF, Manuck SB, Mendelsohn AB, et al. Cholesterol reduction and non-illness mortality: meta-analysis of randomised clinical trials. BMJ. 2001;322(7277):11–15.
  • Wu S, Ding Y, Wu F, et al. Serum lipid levels and suicidality: a meta-analysis of 65 epidemiological studies. J Psychiatry Neurosci. 2016;41(1):56–69.
  • Daray FM, Mann JJ, Sublette ME. How lipids may affect risk for suicidal behavior. J Psychiatr Res. 2018;104:16–23.

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