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Research Articles

Cross-sectional analysis of depressive symptom profiles and serum C-reactive protein levels: data from the Northern Finland 1966 birth cohort

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Pages 95-102 | Received 23 May 2023, Accepted 15 Oct 2023, Published online: 31 Oct 2023

References

  • Howren MB, Lamkin DM, Suls J. Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis. Psychosom Med. 2009;71(2):171–186. doi: 10.1097/PSY.0b013e3181907c1b.
  • Dowlati Y, Herrmann N, Swardfager W, et al. A meta-analysis of cytokines in major depression. Biol Psychiatry. 2010;67(5):446–457. doi: 10.1016/j.biopsych.2009.09.033.
  • Osimo EF, Baxter LJ, Lewis G, et al. Prevalence of low-grade inflammation in depression: a systematic review and meta-analysis of CRP levels. Psychol Med. 2019;49(12):1958–1970. doi: 10.1017/S0033291719001454.
  • Osimo EF, Pillinger T, Rodriguez IM, et al. Inflammatory markers in depression: a meta-analysis of mean differences and variability in 5,166 patients and 5,083 controls. Brain Behav Immun. 2020;87:901–909. doi: 10.1016/j.bbi.2020.02.010.
  • Lamers F, Vogelzangs N, Merikangas KR, et al. Evidence for a differential role of HPA-axis function, inflammation, and metabolic syndrome in melancholic versus atypical depression. Mol Psychiatry. 2013;18(6):692–699. doi: 10.1038/mp.2012.144.
  • Karlović D, Serretti A, Vrkić N, et al. Serum concentrations of CRP, IL-6, TNF-α, and cortisol in major depressive disorder with melancholic or atypical features. Psychiatry Res. 2012;198(1):74–80. doi: 10.1016/j.psychres.2011.12.007.
  • Hickman RJ, Khambaty T, Stewart JC. C-reactive protein is elevated in atypical but not nonatypical depression: data from the national health and nutrition examination survey (NHANES) 1999-2004. J Behav Med. 2014;37(4):621–629. doi: 10.1007/s10865-013-9510-0.
  • Rudolf S, Greggersen W, Kahl KG, et al. Elevated IL-6 levels in patients with atypical depression but not in patients with typical depression. Psychiatry Res. 2014;217(1-2):34–38. doi: 10.1016/j.psychres.2014.02.016.
  • Lamers F, Bot M, Jansen R, et al. Serum proteomic profiles of depressive subtypes. Transl Psychiatry. 2016;6(7):e851–e851. doi: 10.1038/tp.2016.115.
  • Křenek P, Hořínková J, Bartečků E. Peripheral inflammatory markers in subtypes and core features of depression: a systematized review. Psychopathology. 2023;56(5):403–416. doi: 10.1159/000528907.
  • Benazzi F. Can only reversed vegetative symptoms define atypical depression? Eur Arch Psychiatry Clin Neurosci. 2002;252(6):288–293. doi: 10.1007/s00406-002-0395-0.
  • Levitan RD, Lesage A, Parikh SV, et al. Reversed neurovegetative symptoms of depression: a community study of Ontario. Am J Psychiatry. 1997;154(7):934–940. doi: 10.1176/ajp.154.7.934.
  • Sullivan PF, Kessler RC, Kendler KS. Latent class analysis of lifetime depressive symptoms in the national comorbidity survey. Am J Psychiatry. 1998;155(10):1398–1406. doi: 10.1176/ajp.155.10.1398.
  • Nordström T, Miettunen J, Auvinen J, et al. Cohort profile: 46 years of follow-up of the Northern Finland birth cohort 1966 (NFBC1966). Int J Epidemiol. 2022;50(6):1786–1787j. doi: pc124152.oulu.fi:9443/10.1093/ije/dyab109.
  • Beck AT, Steer RA, Brown G. Beck depression inventory–II. [Database record]. APA PsycTests, 1996. doi: 10.1037/t00742-000.
  • Beck AT, Steer RA, Ball R, et al. Comparison of beck depression Inventories-IA and-II in psychiatric outpatients. J Pers Assess. 1996;67(3):588–597. doi: 10.1207/s15327752jpa6703_13.
  • Liukkonen T, Silvennoinen-Kassinen S, Jokelainen J, et al. The association between C-reactive protein levels and depression: results from the Northern Finland 1966 birth cohort study. Biol Psychiatry. 2006;60(8):825–830. doi: 10.1016/j.biopsych.2006.02.016.
  • Liukkonen T, Räsänen P, Ruokonen A, et al. C-reactive protein levels and sleep disturbances: observations based on the Northern Finland 1966 birth cohort study. Psychosom Med. 2007;69(8):756–761. doi: 10.1097/PSY.0b013e318157cb96.
  • Pearson TA, Mensah GA, Alexander RW, et al. Markers of inflammation and cardiovascular disease: application to clinical and public health practice. A statement for healthcare professionals from the centers for disease control and prevention and the American heart association. Circulation. 2003;107(3):499–511. doi: 10.1161/01.cir.0000052939.59093.45.
  • Roy A, DeJong J, Lamparski D, et al. Depression among alcoholics: relationship to clinical and cerebrospinal fluid variables. Arch Gen Psychiatry. 1991;48(5):428–432. doi: 10.1001/archpsyc.1991.01810290040007.
  • Volpato S, Pahor M, Ferrucci L, et al. Relationship of alcohol intake with inflammatory markers and plasminogen activator inhibitor-1 in well-functioning older adults: the health, aging, and body composition study. Circulation. 2004;109(5):607–612. doi: 10.1161/01.CIR.0000109503.13955.00.
  • Pan A, Keum N, Okereke OI, et al. Bidirectional association between depression and metabolic syndrome: a systematic review and meta-analysis of epidemiological studies. Diabetes Care. 2012;35(5):1171–1180. doi: 10.2337/dc11-2055.
  • Voils SA, Cooper-DeHoff RM. Association between high sensitivity C-reactive protein and metabolic syndrome in subjects completing the national health and nutrition examination survey (NHANES) 2009-10. Diabetes Metab Syndr. 2014;8(2):88–90. doi: 10.1016/j.dsx.2014.04.021.
  • Luger TM, Suls J, Vander Weg MW. How robust is the association between smoking and depression in adults? A meta-analysis using linear mixed-effects models. Addict Behav. 2014;39(10):1418–1429. doi: 10.1016/j.addbeh.2014.05.011.
  • Gallus S, Lugo A, Suatoni P, et al. Effect of tobacco smoking cessation on C-reactive protein levels in a cohort of low-dose computed tomography screening participants. Sci Rep. 2018;8(1):12908. doi: 10.1038/s41598-018-29867-9.
  • Goodwin RD. Association between physical activity and mental disorders among adults in the United States. Prev Med. 2003;36(6):698–703. doi: 10.1016/S0091-7435(03)00042-2.
  • Lee DH, de Rezende LFM, Eluf-Neto J, et al. Association of type and intensity of physical activity with plasma biomarkers of inflammation and insulin response. Int J Cancer. 2019;145(2):360–369. doi: 10.1002/ijc.32111.
  • Hiles SA, Baker AL, de Malmanche T, et al. Interleukin-6, C-reactive protein, and interleukin-10 after antidepressant treatment in people with depression: a meta-analysis. Psychol Med. 2012b;42(10):2015–2026. doi: 10.1017/S0033291712000128.
  • Domènech-Abella J, Mundó J, Leonardi M, et al. The association between socioeconomic status and depression among older adults in Finland, Poland, and Spain: a comparative cross-sectional study of distinct measures and pathways. J Affect Disord. 2018;241:311–318. doi: 10.1016/j.jad.2018.08.077.
  • Muscatell KA, Brosso SN, Humphreys KL. Socioeconomic status and inflammation: a meta-analysis. Mol Psychiatry. 2020;25(9):2189–2199. doi: 10.1038/s41380-018-0259-2.
  • Joffe H, Cohen LS. Estrogen, serotonin, and mood disturbance: where is the therapeutic bridge? Biol Psychiatry. 1998;44(9):798–811. doi: 10.1016/S0006-3223(98)00169-3.
  • Skovlund CW, Mørch LS, Kessing LV, et al. Association of hormonal contraception with depression. JAMA Psychiatry. 2016;73(11):1154–1162. doi: 10.1001/jamapsychiatry.2016.2387.
  • Dreon DM, Slavin JL, Phinney SD. Oral contraceptive use and increased plasma concentration of C-reactive protein. Life Sci. 2003;73(10):1245–1252. doi: 10.1016/s0024-3205(03)00425-9.
  • Sundell L, Salomaa V, Vartiainen E, et al. Increased stroke risk is related to a binge-drinking habit. Stroke. 2008;39(12):3179–3184. doi: 10.1161/STROKEAHA.108.520817.
  • Alberti KG, Zimmet P, Shaw J, IDF Epidemiology Task Force Consensus Group. The metabolic syndrome: a new worldwide definition. Lancet. 2005;366(9491):1059–1062. doi: 10.1016/S0140-6736(05)67402-8.
  • Jokela M, Virtanen M, Batty GD, et al. Inflammation and specific symptoms of depression. JAMA Psychiatry. 2016;73(1):87–88. doi: 10.1001/jamapsychiatry.2015.1977.
  • Lamers F, Milaneschi Y, de Jonge P, et al. Metabolic and inflammatory markers: associations with individual depressive symptoms. Psychol Med. 2018;48(7):1102–1110. doi: 10.1017/S0033291717002483.
  • Valkanova V, Ebmeier KP, Allan CL. CRP, IL-6, and depression: a systematic review and meta-analysis of longitudinal studies. J Affect Disord. 2013;150(3):736–744. doi: 10.1016/j.jad.2013.06.004.
  • Wium-Andersen MK, Ørsted DD, Nielsen SF, et al. Elevated C-reactive protein levels, psychological distress, and depression in 73,131 individuals. JAMA Psychiatry. 2013;70(2):176–184. doi: 10.1001/2013.jamapsychiatry.102.
  • Zalli A, Jovanova O, Hoogendijk WJG, et al. Low-grade inflammation predicts persistence of depressive symptoms. Psychopharmacology (Berl). 2016;233(9):1669–1678. doi: 10.1007/s00213-015-3919-9.
  • Smith KJ, Au B, Ollis L, et al. The association between C-reactive protein, interleukin-6 and depression among older adults in the community: a systematic review and meta-analysis. Exp Gerontol. 2018;102:109–132. doi: 10.1016/j.exger.2017.12.005.
  • Osimo EF, Stochl J, Zammit S, et al. Longitudinal population subgroups of CRP and risk of depression in the ALSPAC birth cohort. Compr Psychiatry. 2020;96:152143. doi: 10.1016/j.comppsych.2019.152143.
  • Khandaker GM, Pearson RM, Zammit S, et al. Association of serum interleukin 6 and C-reactive protein in childhood with depression and psychosis in young adult life: a population-based longitudinal study. JAMA Psychiatry. 2014;71(10):1121–1128. doi: 10.1001/jamapsychiatry.2014.1332.
  • Chocano-Bedoya PO, Mirzaei F, O’Reilly EJ, et al. C-reactive protein, interleukin-6, soluble tumor necrosis factor α receptor 2, and incident clinical depression. J Affect Disord. 2014;163:25–32. doi: 10.1016/j.jad.2014.03.023.
  • Rudaz DA, Vandeleur CL, Gebreab SZ, et al. Partially distinct combinations of psychological, metabolic, and inflammatory risk factors are prospectively associated with the onset of the subtypes of major depressive disorder in midlife. J Affect Disord. 2017;222:195–203. doi: 10.1016/j.jad.2017.07.016.
  • Lamers F, Milaneschi Y, Smit JH, et al. Longitudinal association between depression and inflammatory markers: results from The Netherlands study of depression and anxiety. Biol Psychiatry. 2019;85(10):829–837. doi: 10.1016/j.biopsych.2018.12.020.
  • Au B, Smith KJ, Gariépy G, et al. The longitudinal associations between C-reactive protein and depressive symptoms: evidence from the english longitudinal study of ageing (ELSA). Int J Geriatr Psychiatry. 2015;30(9):976–984. doi: 10.1002/gps.4250.
  • Glaus J, von Känel R, Lasserre AM, et al. Mood disorders and circulating levels of inflammatory markers in a longitudinal population-based study. Psychol Med. 2018;48(6):961–973. doi: 10.1017/S0033291717002744.
  • Huang M, Su S, Goldberg J, et al. Longitudinal association of inflammation with depressive symptoms: a 7-year cross-lagged twin difference study. Brain Behav Immun. 2019;75:200–207. doi: 10.1016/j.bbi.2018.10.007.
  • Wium-Andersen MK, Orsted DD, Nordestgaard BG. Elevated C-reactive protein, depression, somatic diseases, and all-cause mortality: a mendelian randomization study. Biol Psychiatry. 2014;76(3):249–257. doi: 10.1016/j.biopsych.2013.10.009.
  • Pitharouli MC, Hagenaars SP, Glanville KP, et al. Elevated C-Reactive protein in patients With depression, independent of genetic, health, and psychosocial factors: results From the UK biobank. Am J Psychiatry. 2021;178(6):522–529. doi: 10.1176/appi.ajp.2020.20060947.
  • Ballesio A. Inflammatory hypotheses of sleep disturbance - depression link: update and research agenda. Brain Behav Immun Health. 2023;31:100647. doi: 10.1016/j.bbih.2023.100647.
  • Kappelmann N, Czamara D, Rost N, et al. Polygenic risk for immuno-metabolic markers and specific depressive symptoms: a multi-sample network analysis study. Brain Behav Immun. 2021;95:256–268. doi: 10.1016/j.bbi.2021.03.024.
  • Simmons WK, Burrows K, Avery JA, et al. Appetite changes reveal depression subgroups with distinct endocrine, metabolic, and immune states. Mol Psychiatry. 2020;25(7):1457–1468. doi: 10.1038/s41380-018-0093-6.
  • Cosgrove KT, Burrows K, Avery JA, et al. Appetite change profiles in depression exhibit differential relationships between systemic inflammation and activity in reward and interoceptive neurocircuitry. Brain Behav Immun. 2020;83:163–171. doi: 10.1016/j.bbi.2019.10.006.
  • American Psychiatric Association. Diagnostic and statistical manual of mental disorders (5th ed.). Arlington: American Psychiatric Publishing; 2013.
  • Wium-Andersen MK, Ørsted DD, Nordestgaard BG. Elevated C-reactive protein and late-onset bipolar disorder in 78 809 individuals from the general population. Br J Psychiatry. 2016;208(2):138–145. doi: 10.1192/bjp.bp.114.150870.
  • Penninx BWJH. Using the power of a giant wisely: confirming inflammation in depression. Am J Psychiatry. 2021;178(6):480–482. doi: 10.1176/appi.ajp.2021.21040332.

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